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The map label for this gene is sucD1 [H]

Identifier: 193212664

GI number: 193212664

Start: 1114829

End: 1116655

Strand: Direct

Name: sucD1 [H]

Synonym: Cpar_1009

Alternate gene names: 193212664

Gene position: 1114829-1116655 (Clockwise)

Preceding gene: 193212663

Following gene: 193212666

Centisome position: 48.7

GC content: 58.13

Gene sequence:

>1827_bases
GTGAGCATTCTCGCAAATAAAGATACCCGGGCAGTCATCATCGGCGGCGTAGCAGGCGTCAATGCGGCAAAACGCATGGC
CCAGTTTGACTTTCTGGTCAACCGTCCGCTGACCGTCCAGGCTTTCGTGTATCCGCCCGAAGCCGGCCAGCAGAAAGAGA
TCTTCCGCGGCGGCGAACTCAAGAACGTCACCGTTTACGACTCCCTGGCTCCTGCTCTCGAAGAGCATCCGGATATCAAC
ACCGCACTTATCTACCTCGGCGCATCCCGCGCTGCCCAGGCTGCCAAAGAGGCGCTTGAGTCCCCGAACATTCAGCTGGT
CTCGATGATCACTGAAGGTGTTCCGGAAAAGGACGCCAAGCGTCTGAGAAAACTTGCCCAGAAGCTTGGCAAGATGCTGA
ATGGCCCGTCCTCCATCGGTATCATGTCTGCCGGCGAGTGCCGCCTTGGCGTGATCGGTGGTGAGTTCAAGAACCTGAAG
CTTTGCAACCTGTACCGTCAGGGTTCGTTCGGCGTTCTGACCAAGTCCGGTGGCCTGTCCAACGAAGCCATGTGGCTTTG
TGCCCAGAACGGCGACGGCATCACCTCTGCCGTGGCTATCGGTGGCGACGCCTATCCCGGCACCGACTTCGTGACCTACC
TCGAAATGTTCGAGAAGGATCCCGCAACCAAGGCGGTCGTCATGATCGGCGAGGTTGGTGGTAATCTCGAAGAAGAAGCC
GCAGAGTGGCTGGCCGCTGAGCCGCGCCGCATCAAGCTGATCGCCGCCATCGGTGGTACCTGCCAGGAAGTTCTGCCTCA
GGGTATGAAGTTCGGCCATGCCGGTGCCAAGGAAGGCAAGAAAGGTGCAGGCTCCGCCCGCTCCAAGATGAACGCACTCC
GCGACGCCGGTGCGTACGTTCCGGATACCTTCGGTGGTCTCAGCAAGGAGATCAAAAAAGTCTATGAAGAGCTGATCGCT
GCCGGTGAAATCAGCACCGAGATCGACGAGGCTGTGCTGCCTGAGCTGCCGCCGAGCGTTCAGGAGGTCATGAAGCAGGG
TGAAGTGATCGTTGAGCCGCTCATCCGCACCACCATTTCCGACGACCGTGGCGAAGAGCCGCGCTATGCCGGTTACGCCG
CTTCGGAGCTCTGCTCGAAAGGCTATGGCATCGAAGATGTCATCGGCCTGCTCTGGAACAAAAAGCTTCCGACCCGCGAA
GAGTCCGAAATTATCAAACGCATCGTCATGATTTCGGCAGACCACGGTCCTGCCGTGTCGGGTGCGTTTGGTTCGATTCT
CGCCGCTTGCGCAGGCATCGACATGCCGCAGGCTGTTTCGGCTGGCATGACCATGATCGGCCCCCGTTTCGGCGGCGCCG
TGACCAATGCCGGCAAATACTTCAAGATGGCTGTCGAGGACTACCCGAACGACATCCCCGGCTTCCTTTCCTGGATGAAG
AAGAATGTCGGCCCGGTTCCCGGTATCGGCCACAGGGTCAAGAGCGTCAAGAATCCCGACCAGCGCGTGAAGTATCTGGT
GAGCTACATCAAGAACGAAACGTCGCTGCACACTCCGTGCCTCGACTACGCGCTTGAGGTCGAGAAGGTCACTACGGCCA
AGAAGGGCAACCTGATTCTGAACGTTGATGGCACCATCGGCTGCATTCTGATGGACCTCGACTTCCCGGTGCACTCCCTG
AACGGCTTCTTCGTTCTGGCCCGTACCATCGGTATGATCGGCCACTGGATCGATCAGAACAACCAGAACTCGCGCCTCAT
CAGGCTCTACGACTACCTGATCAACTACGCAGTGAAACCTGAACAAGAGGTTCCTGAAAAGAAGTAA

Upstream 100 bases:

>100_bases
CGATGACCGATATCGTCGATATGGCGATGAAGTCTTGAGGGATGTCCTTGTAAGATGTTGAAATTTAAGACTATAGAAAC
TCATTAAATCTGATTGAACC

Downstream 100 bases:

>100_bases
GGTAATAGTATTACAGGACGGGACGTGGTGATCCCACGTTCCGTTTCAACAGTAAAAAAGCAGGCCAAAAGCCTGCTTTT
TCTGTTATTCTGAGGATAGC

Product: ATP-citrate lyase/succinyl-CoA ligase

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha 1; SCS-alpha 1 [H]

Number of amino acids: Translated: 608; Mature: 607

Protein sequence:

>608_residues
MSILANKDTRAVIIGGVAGVNAAKRMAQFDFLVNRPLTVQAFVYPPEAGQQKEIFRGGELKNVTVYDSLAPALEEHPDIN
TALIYLGASRAAQAAKEALESPNIQLVSMITEGVPEKDAKRLRKLAQKLGKMLNGPSSIGIMSAGECRLGVIGGEFKNLK
LCNLYRQGSFGVLTKSGGLSNEAMWLCAQNGDGITSAVAIGGDAYPGTDFVTYLEMFEKDPATKAVVMIGEVGGNLEEEA
AEWLAAEPRRIKLIAAIGGTCQEVLPQGMKFGHAGAKEGKKGAGSARSKMNALRDAGAYVPDTFGGLSKEIKKVYEELIA
AGEISTEIDEAVLPELPPSVQEVMKQGEVIVEPLIRTTISDDRGEEPRYAGYAASELCSKGYGIEDVIGLLWNKKLPTRE
ESEIIKRIVMISADHGPAVSGAFGSILAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKMAVEDYPNDIPGFLSWMK
KNVGPVPGIGHRVKSVKNPDQRVKYLVSYIKNETSLHTPCLDYALEVEKVTTAKKGNLILNVDGTIGCILMDLDFPVHSL
NGFFVLARTIGMIGHWIDQNNQNSRLIRLYDYLINYAVKPEQEVPEKK

Sequences:

>Translated_608_residues
MSILANKDTRAVIIGGVAGVNAAKRMAQFDFLVNRPLTVQAFVYPPEAGQQKEIFRGGELKNVTVYDSLAPALEEHPDIN
TALIYLGASRAAQAAKEALESPNIQLVSMITEGVPEKDAKRLRKLAQKLGKMLNGPSSIGIMSAGECRLGVIGGEFKNLK
LCNLYRQGSFGVLTKSGGLSNEAMWLCAQNGDGITSAVAIGGDAYPGTDFVTYLEMFEKDPATKAVVMIGEVGGNLEEEA
AEWLAAEPRRIKLIAAIGGTCQEVLPQGMKFGHAGAKEGKKGAGSARSKMNALRDAGAYVPDTFGGLSKEIKKVYEELIA
AGEISTEIDEAVLPELPPSVQEVMKQGEVIVEPLIRTTISDDRGEEPRYAGYAASELCSKGYGIEDVIGLLWNKKLPTRE
ESEIIKRIVMISADHGPAVSGAFGSILAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKMAVEDYPNDIPGFLSWMK
KNVGPVPGIGHRVKSVKNPDQRVKYLVSYIKNETSLHTPCLDYALEVEKVTTAKKGNLILNVDGTIGCILMDLDFPVHSL
NGFFVLARTIGMIGHWIDQNNQNSRLIRLYDYLINYAVKPEQEVPEKK
>Mature_607_residues
SILANKDTRAVIIGGVAGVNAAKRMAQFDFLVNRPLTVQAFVYPPEAGQQKEIFRGGELKNVTVYDSLAPALEEHPDINT
ALIYLGASRAAQAAKEALESPNIQLVSMITEGVPEKDAKRLRKLAQKLGKMLNGPSSIGIMSAGECRLGVIGGEFKNLKL
CNLYRQGSFGVLTKSGGLSNEAMWLCAQNGDGITSAVAIGGDAYPGTDFVTYLEMFEKDPATKAVVMIGEVGGNLEEEAA
EWLAAEPRRIKLIAAIGGTCQEVLPQGMKFGHAGAKEGKKGAGSARSKMNALRDAGAYVPDTFGGLSKEIKKVYEELIAA
GEISTEIDEAVLPELPPSVQEVMKQGEVIVEPLIRTTISDDRGEEPRYAGYAASELCSKGYGIEDVIGLLWNKKLPTREE
SEIIKRIVMISADHGPAVSGAFGSILAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKMAVEDYPNDIPGFLSWMKK
NVGPVPGIGHRVKSVKNPDQRVKYLVSYIKNETSLHTPCLDYALEVEKVTTAKKGNLILNVDGTIGCILMDLDFPVHSLN
GFFVLARTIGMIGHWIDQNNQNSRLIRLYDYLINYAVKPEQEVPEKK

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI38569423, Length=603, Percent_Identity=34.9917081260365, Blast_Score=358, Evalue=6e-99,
Organism=Homo sapiens, GI38569421, Length=603, Percent_Identity=34.9917081260365, Blast_Score=358, Evalue=7e-99,
Organism=Homo sapiens, GI109452591, Length=216, Percent_Identity=36.1111111111111, Blast_Score=101, Evalue=3e-21,
Organism=Escherichia coli, GI1786949, Length=237, Percent_Identity=33.7552742616034, Blast_Score=129, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17557344, Length=604, Percent_Identity=37.5827814569536, Blast_Score=373, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17551266, Length=607, Percent_Identity=36.7380560131796, Blast_Score=368, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17550194, Length=308, Percent_Identity=34.0909090909091, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17553126, Length=316, Percent_Identity=31.3291139240506, Blast_Score=121, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6324716, Length=254, Percent_Identity=32.2834645669291, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281363477, Length=609, Percent_Identity=35.9605911330049, Blast_Score=354, Evalue=8e-98,
Organism=Drosophila melanogaster, GI281363475, Length=611, Percent_Identity=36.0065466448445, Blast_Score=354, Evalue=1e-97,
Organism=Drosophila melanogaster, GI281363473, Length=611, Percent_Identity=36.0065466448445, Blast_Score=354, Evalue=1e-97,
Organism=Drosophila melanogaster, GI21356559, Length=236, Percent_Identity=33.8983050847458, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28574296, Length=214, Percent_Identity=35.5140186915888, Blast_Score=102, Evalue=7e-22,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 65530; Mature: 65399

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00238 OPSIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILANKDTRAVIIGGVAGVNAAKRMAQFDFLVNRPLTVQAFVYPPEAGQQKEIFRGGEL
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHCCCCC
KNVTVYDSLAPALEEHPDINTALIYLGASRAAQAAKEALESPNIQLVSMITEGVPEKDAK
CEEEEHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEHHHHCCCCCHHHH
RLRKLAQKLGKMLNGPSSIGIMSAGECRLGVIGGEFKNLKLCNLYRQGSFGVLTKSGGLS
HHHHHHHHHHHHHCCCCCCCEEECCCCEEEEECCCCCCEEEEEEEECCCCEEEECCCCCC
NEAMWLCAQNGDGITSAVAIGGDAYPGTDFVTYLEMFEKDPATKAVVMIGEVGGNLEEEA
CCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHH
AEWLAAEPRRIKLIAAIGGTCQEVLPQGMKFGHAGAKEGKKGAGSARSKMNALRDAGAYV
HHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PDTFGGLSKEIKKVYEELIAAGEISTEIDEAVLPELPPSVQEVMKQGEVIVEPLIRTTIS
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCC
DDRGEEPRYAGYAASELCSKGYGIEDVIGLLWNKKLPTREESEIIKRIVMISADHGPAVS
CCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHEECCCCCCCC
GAFGSILAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKMAVEDYPNDIPGFLSWMK
CHHHHHHHHHHCCCCHHHHHCCCHHCCCCCCCCCCCCCHHEEEEHHHCCCCCHHHHHHHH
KNVGPVPGIGHRVKSVKNPDQRVKYLVSYIKNETSLHTPCLDYALEVEKVTTAKKGNLIL
HCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEE
NVDGTIGCILMDLDFPVHSLNGFFVLARTIGMIGHWIDQNNQNSRLIRLYDYLINYAVKP
EECCCEEEEEEECCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
EQEVPEKK
HHCCCCCC
>Mature Secondary Structure 
SILANKDTRAVIIGGVAGVNAAKRMAQFDFLVNRPLTVQAFVYPPEAGQQKEIFRGGEL
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHCCCCC
KNVTVYDSLAPALEEHPDINTALIYLGASRAAQAAKEALESPNIQLVSMITEGVPEKDAK
CEEEEHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEHHHHCCCCCHHHH
RLRKLAQKLGKMLNGPSSIGIMSAGECRLGVIGGEFKNLKLCNLYRQGSFGVLTKSGGLS
HHHHHHHHHHHHHCCCCCCCEEECCCCEEEEECCCCCCEEEEEEEECCCCEEEECCCCCC
NEAMWLCAQNGDGITSAVAIGGDAYPGTDFVTYLEMFEKDPATKAVVMIGEVGGNLEEEA
CCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHH
AEWLAAEPRRIKLIAAIGGTCQEVLPQGMKFGHAGAKEGKKGAGSARSKMNALRDAGAYV
HHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PDTFGGLSKEIKKVYEELIAAGEISTEIDEAVLPELPPSVQEVMKQGEVIVEPLIRTTIS
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCC
DDRGEEPRYAGYAASELCSKGYGIEDVIGLLWNKKLPTREESEIIKRIVMISADHGPAVS
CCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHEECCCCCCCC
GAFGSILAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKMAVEDYPNDIPGFLSWMK
CHHHHHHHHHHCCCCHHHHHCCCHHCCCCCCCCCCCCCHHEEEEHHHCCCCCHHHHHHHH
KNVGPVPGIGHRVKSVKNPDQRVKYLVSYIKNETSLHTPCLDYALEVEKVTTAKKGNLIL
HCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEE
NVDGTIGCILMDLDFPVHSLNGFFVLARTIGMIGHWIDQNNQNSRLIRLYDYLINYAVKP
EECCCEEEEEEECCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
EQEVPEKK
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]