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The map label for this gene is sucC [H]

Identifier: 193212663

GI number: 193212663

Start: 1113570

End: 1114766

Strand: Direct

Name: sucC [H]

Synonym: Cpar_1008

Alternate gene names: 193212663

Gene position: 1113570-1114766 (Clockwise)

Preceding gene: 193212661

Following gene: 193212664

Centisome position: 48.64

GC content: 56.06

Gene sequence:

>1197_bases
ATGGCTAAAATTCTTGAAGGGCCGGCCATGAAGTTGTTCAACAAATGGGGCATTCCTGTGCCTAATTATGTTGTCATCAT
GGACCCTGACCGTCTTGCACAGCTTGGTGAAGCTAATAAATGGCTGCGTGAATCGAAACTCGTCGTCAAGGCACACGAAG
CCATCGGCGGCCGTTTCAAACTCGGTCTCGTTAAAATTGGTCTTAATCTCGAACAGGCCATCGAAGCTGCCAAAGAGATG
CTTGGCGCCAAAGTCGGCACGGCTGAAATCGGCCAGGTCATCATCGCTGAAATGCTCGAGCATGACGCGGAGTTCTACGT
TTCGATTATCGGTAACAAAGATGGCGCTGAACTGCTGATTTCCAAGCACGGCGGCGTCGATATCGAAGACAACTGGGACA
GCGTCCGCCGTATCCAGATCGAACTCGACGAGAATCCCACCATCGAGCGACTCACCGAGCTTGCCAAGGATGCCGGTTTC
GAAGGCGAAATCGCCGAGCGCGTCGGCAAGATCTGCTCCCGTCTCATTCTCTGTTTCGACAACGAGGACGCACAGTCCAT
CGAAATCAACCCGCTGGTTATCCGCAAGAGCGACATGCGCTTCGCCGCGCTTGACGCCGTTATGAACGTGGACTATGATG
CCCGGTTCCGCCATGCCGACTGGGATTTCAAGCCGGTTTCCGAAATCGGCCGTCCGTTCACCGAAGCCGAGCAGCAGATC
ATGGAGATCGACTCCAGGATCAAGGGTTCGGTCAAGTTCGTTGAGGTTCCCGGTGGTGAAATCGCTCTGCTGACCGCAGG
CGGCGGCGCATCGGTCTTCTATGCCGACGCAGTCGTGGCTCGCGGCGGAACCATCGCCAACTATGCAGAATATTCGGGCG
ACCCGGCCGACTGGGCTGTGGAAGCGCTCACCGAAACCATCTGCCGTCTGCCCAACATCAAGCACATCATTGTCGGCGGC
GCTATCGCCAACTTTACCGACGTGAAGGCTACCTTCAGCGGTATCATCAACGGCTTCCGCGAAAGCAAGTCGAAGGGCTA
CCTCGAAGGCGTAAAAATCTGGGTGCGCCGTGGCGGCCCGAACGAAGCTCAGGGCCTTGCCGCTATCAAGCAGCTCCAGG
AGGAAGGCTTCGACATTCACGTCTACGACCGCAGCATGCCGATGACCGATATCGTCGATATGGCGATGAAGTCTTGA

Upstream 100 bases:

>100_bases
AACGAGTCTTAACGTCTTGGTAACAAGACAGAATATAGCTATATTTAAACTTTGCACTTTTCTTTTCGCACAATTACCTG
AAAACGTAAACACATAGAGC

Downstream 100 bases:

>100_bases
GGGATGTCCTTGTAAGATGTTGAAATTTAAGACTATAGAAACTCATTAAATCTGATTGAACCGTGAGCATTCTCGCAAAT
AAAGATACCCGGGCAGTCAT

Product: ATP-grasp domain-containing protein

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAKILEGPAMKLFNKWGIPVPNYVVIMDPDRLAQLGEANKWLRESKLVVKAHEAIGGRFKLGLVKIGLNLEQAIEAAKEM
LGAKVGTAEIGQVIIAEMLEHDAEFYVSIIGNKDGAELLISKHGGVDIEDNWDSVRRIQIELDENPTIERLTELAKDAGF
EGEIAERVGKICSRLILCFDNEDAQSIEINPLVIRKSDMRFAALDAVMNVDYDARFRHADWDFKPVSEIGRPFTEAEQQI
MEIDSRIKGSVKFVEVPGGEIALLTAGGGASVFYADAVVARGGTIANYAEYSGDPADWAVEALTETICRLPNIKHIIVGG
AIANFTDVKATFSGIINGFRESKSKGYLEGVKIWVRRGGPNEAQGLAAIKQLQEEGFDIHVYDRSMPMTDIVDMAMKS

Sequences:

>Translated_398_residues
MAKILEGPAMKLFNKWGIPVPNYVVIMDPDRLAQLGEANKWLRESKLVVKAHEAIGGRFKLGLVKIGLNLEQAIEAAKEM
LGAKVGTAEIGQVIIAEMLEHDAEFYVSIIGNKDGAELLISKHGGVDIEDNWDSVRRIQIELDENPTIERLTELAKDAGF
EGEIAERVGKICSRLILCFDNEDAQSIEINPLVIRKSDMRFAALDAVMNVDYDARFRHADWDFKPVSEIGRPFTEAEQQI
MEIDSRIKGSVKFVEVPGGEIALLTAGGGASVFYADAVVARGGTIANYAEYSGDPADWAVEALTETICRLPNIKHIIVGG
AIANFTDVKATFSGIINGFRESKSKGYLEGVKIWVRRGGPNEAQGLAAIKQLQEEGFDIHVYDRSMPMTDIVDMAMKS
>Mature_397_residues
AKILEGPAMKLFNKWGIPVPNYVVIMDPDRLAQLGEANKWLRESKLVVKAHEAIGGRFKLGLVKIGLNLEQAIEAAKEML
GAKVGTAEIGQVIIAEMLEHDAEFYVSIIGNKDGAELLISKHGGVDIEDNWDSVRRIQIELDENPTIERLTELAKDAGFE
GEIAERVGKICSRLILCFDNEDAQSIEINPLVIRKSDMRFAALDAVMNVDYDARFRHADWDFKPVSEIGRPFTEAEQQIM
EIDSRIKGSVKFVEVPGGEIALLTAGGGASVFYADAVVARGGTIANYAEYSGDPADWAVEALTETICRLPNIKHIIVGGA
IANFTDVKATFSGIINGFRESKSKGYLEGVKIWVRRGGPNEAQGLAAIKQLQEEGFDIHVYDRSMPMTDIVDMAMKS

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI38569421, Length=382, Percent_Identity=33.7696335078534, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI38569423, Length=382, Percent_Identity=33.7696335078534, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI11321583, Length=305, Percent_Identity=28.5245901639344, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI157779135, Length=409, Percent_Identity=25.6723716381418, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=26.1838440111421, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1786948, Length=324, Percent_Identity=25.6172839506173, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551266, Length=400, Percent_Identity=33.5, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17557344, Length=418, Percent_Identity=30.8612440191388, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17539378, Length=349, Percent_Identity=26.9340974212034, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17567829, Length=396, Percent_Identity=26.5151515151515, Blast_Score=75, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321683, Length=339, Percent_Identity=26.5486725663717, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281363475, Length=387, Percent_Identity=32.8165374677003, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI281363473, Length=387, Percent_Identity=32.8165374677003, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI281363477, Length=387, Percent_Identity=32.8165374677003, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI21356231, Length=391, Percent_Identity=25.8312020460358, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281361397, Length=338, Percent_Identity=26.6272189349112, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI281361395, Length=338, Percent_Identity=26.6272189349112, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI161078106, Length=338, Percent_Identity=26.6272189349112, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24645208, Length=338, Percent_Identity=26.6272189349112, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 43725; Mature: 43593

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKILEGPAMKLFNKWGIPVPNYVVIMDPDRLAQLGEANKWLRESKLVVKAHEAIGGRFK
CCCCCCCHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHEEEHHHCCCEEE
LGLVKIGLNLEQAIEAAKEMLGAKVGTAEIGQVIIAEMLEHDAEFYVSIIGNKDGAELLI
EEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEE
SKHGGVDIEDNWDSVRRIQIELDENPTIERLTELAKDAGFEGEIAERVGKICSRLILCFD
ECCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEC
NEDAQSIEINPLVIRKSDMRFAALDAVMNVDYDARFRHADWDFKPVSEIGRPFTEAEQQI
CCCCCEEECCEEEEEECCCHHHHHHHHHCCCCCCCEECCCCCCCCHHHHCCCHHHHHHHH
MEIDSRIKGSVKFVEVPGGEIALLTAGGGASVFYADAVVARGGTIANYAEYSGDPADWAV
HHHHHHCCCCEEEEECCCCCEEEEEECCCCEEEEEHHHHHCCCCEECHHHCCCCHHHHHH
EALTETICRLPNIKHIIVGGAIANFTDVKATFSGIINGFRESKSKGYLEGVKIWVRRGGP
HHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEECCCC
NEAQGLAAIKQLQEEGFDIHVYDRSMPMTDIVDMAMKS
CHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure 
AKILEGPAMKLFNKWGIPVPNYVVIMDPDRLAQLGEANKWLRESKLVVKAHEAIGGRFK
CCCCCCHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHEEEHHHCCCEEE
LGLVKIGLNLEQAIEAAKEMLGAKVGTAEIGQVIIAEMLEHDAEFYVSIIGNKDGAELLI
EEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEE
SKHGGVDIEDNWDSVRRIQIELDENPTIERLTELAKDAGFEGEIAERVGKICSRLILCFD
ECCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEC
NEDAQSIEINPLVIRKSDMRFAALDAVMNVDYDARFRHADWDFKPVSEIGRPFTEAEQQI
CCCCCEEECCEEEEEECCCHHHHHHHHHCCCCCCCEECCCCCCCCHHHHCCCHHHHHHHH
MEIDSRIKGSVKFVEVPGGEIALLTAGGGASVFYADAVVARGGTIANYAEYSGDPADWAV
HHHHHHCCCCEEEEECCCCCEEEEEECCCCEEEEEHHHHHCCCCEECHHHCCCCHHHHHH
EALTETICRLPNIKHIIVGGAIANFTDVKATFSGIINGFRESKSKGYLEGVKIWVRRGGP
HHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEECCCC
NEAQGLAAIKQLQEEGFDIHVYDRSMPMTDIVDMAMKS
CHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]