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The map label for this gene is prc [H]

Identifier: 193212639

GI number: 193212639

Start: 1086725

End: 1088836

Strand: Direct

Name: prc [H]

Synonym: Cpar_0984

Alternate gene names: 193212639

Gene position: 1086725-1088836 (Clockwise)

Preceding gene: 193212637

Following gene: 193212647

Centisome position: 47.47

GC content: 53.93

Gene sequence:

>2112_bases
ATGAAATCGCTACGTACGGCACTGTTTCCCGTTTTCCTGATTTTCTCGATCCTGACGATGTCATGGGGTCAATCACAGGC
AGTTCCAGCGAAAGCCGCCGCACCGCCAGCCTTGCTCGCACCGACTCCTGAACAGATGGAGGCCTCGCGCCATCTGGCCC
AGTATCTTATCCAGAACCATTACCGGAAAGTTCCGCTGAACGATTCGCTTTCCCAGCAGATCTTCGACCGCTTCCTGGAT
AATATCGACAACAACCGGAGCTACTTTACGGCCTCAGACGTCGAAAGACTCAGAAAGGAGTACGGCAACCGCCTCGACGA
CGATTTCATAACCGGTAATCCGGAGGGCGGGTTCGCCATCTACAATCAGTTCCTGAAACGGGCTCGTCAGAAGATGGCGT
TCATGATGAAGGCGCTCAAAACTTCGACATTCGATTTCACCAAGCCCGAAACGCTTGAACTCGAACGAAGCAAAACCGCT
CCCTGGTCGGTTGATCTTGCCGCCCTGCAGGATCAGTGGCGTAAAGAGTTGAAGTATCAGTACCTGAACATGAAGTTCAC
CGGCGAAAAGGGAAAAAGCATCAAGAGCGCGCTTGAAAAGAGTTTCCGGAACCGCCTGAACCTCTTCAACCAGCAGAAGC
CCGAAGACGCTTTCGTGGCCTACATGAATGCCGTGACCACCTCGTTCGATCCCCATACGGACTATTTCTCGCCCGATATG
TATGAGAACTTTCAGATCGACATGAGCCGCTCGCTCGAAGGTATCGGAGCGAAGTTGCAGATGGAGAACGAATACACGGT
GGTGAATGAAATCATTCCCGGCGGGCCGGCTTTCAAGGGCAACCAGCTCAAGAAAGGGGATCAGATTATCGGCGTCGGTC
AGGGCGAGAATGGTGAAATTATCGATGTGGTCGGATGGCGGATCAACGACGTGGTCAAAAAAATCAGGGGTCCCAAAGGA
ACCGTGGTGCGGCTCAAGGTGCTTCCGGCCAGCCAGGCCAACAAGGGGCCGGCCCGCATCATCAGGATTGTCAGAGCCAA
AGTCGATCTGCAGGAGCAGGCAGCCCAGAAGAAGATTATCATCGAAAAAGGTAAAAAGATCGGCGTGATCGTGCTGCCCT
CGTTCTATCTCGATTTCGAAGGTGAACGACAGAATAAAACGAATTACACCAGCACCACACGCGATGTCATCAAGATTCTT
AATGAGCTGAACGCTGCGAAGGTGGATGGTATTATTCTCGACCTGCGTGATAATGGCGGGGGTTCGCTCGAAGAGGCGGT
CAACGTGACCGGCCTGTTCGTTGGACAGGGCCCGGTCGTGCAGGTCAGCAACGCTCTTGGCGGCAAGATGGTGCTCAAGG
ACGAAGAGTATCCGGCATTGTACACCGGGCCGCTTGTTGTGCTGGTCAACCGCTACAGCGCTTCGGCTTCGGAAATTTTT
GCCGCAGCCATTCAGGATTACGGACGTGGCGTCATTGTCGGCGATCGCACGTTCGGCAAGGGCACCGTGCAGAGCATCGT
ATCGATCAAGCGCCCCTTCAGCATGTTCACGAACCAGCCCGATCTTGGCCAGCTCAAGCTGACCGTGGCAAAGTTCTACC
GCATCTCTGGCGGAAGCACCCAGCATATCGGCGTGTTGCCCGACATCGTGCTGCCCTCGATGATCGATCCGGAGGTTGTC
GGCGAAGATACCTACACCAGCAGTCTGCCCTGGACAACCATTTCAAGGGCGGACTACACTCCGGTCGGTTCGGTCAGCCG
CGCCGATATTTCGATGTTGAAAAGCGAGTTCAAAGCGCGGGCTGCAAAGGATAGTCAATACCAGGCCTACCTTGCCGATC
TGGCAACCCTGAACCGTATCAGAAACAAGAAGAGCGTCTCGCTTCAGGAAAAGAACTTCGAGACGGAGAGCAAGACCCTG
AAGCAGATTCAGGATCGCTGGGGTGACGAGAATCTTGAAACCGGCAAGAAAAAGAAAACCGACTTTATCATTCAGGAAAC
CGCCGGTATCATGGATGATCTGATTGACCTCAAAGCTCAGGAGACAGATGCGCCGATGCTTCAGAAACCGGCAGCACAGC
TCATCAAGGCTATGCCGCTAGGGAAGAAATGA

Upstream 100 bases:

>100_bases
AGTTAAATACTATGTTTAGCAAATATAATATATTGAACCAAGATTTGAGGCTCTCGTTACTTTAAAGGTTCTTTTTACCA
ATACGTCATAGTTTATAAAT

Downstream 100 bases:

>100_bases
GTGCTGAGTATGAATAGTTGATCGTTGCCAGGGCGGGCTAGAGATGTCCGCCCTGTCTCTTCTTGTGGGCGATAAAGTAC
TTTACAAGGCAAAATATCTT

Product: carboxyl-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; Protease Re [H]

Number of amino acids: Translated: 703; Mature: 703

Protein sequence:

>703_residues
MKSLRTALFPVFLIFSILTMSWGQSQAVPAKAAAPPALLAPTPEQMEASRHLAQYLIQNHYRKVPLNDSLSQQIFDRFLD
NIDNNRSYFTASDVERLRKEYGNRLDDDFITGNPEGGFAIYNQFLKRARQKMAFMMKALKTSTFDFTKPETLELERSKTA
PWSVDLAALQDQWRKELKYQYLNMKFTGEKGKSIKSALEKSFRNRLNLFNQQKPEDAFVAYMNAVTTSFDPHTDYFSPDM
YENFQIDMSRSLEGIGAKLQMENEYTVVNEIIPGGPAFKGNQLKKGDQIIGVGQGENGEIIDVVGWRINDVVKKIRGPKG
TVVRLKVLPASQANKGPARIIRIVRAKVDLQEQAAQKKIIIEKGKKIGVIVLPSFYLDFEGERQNKTNYTSTTRDVIKIL
NELNAAKVDGIILDLRDNGGGSLEEAVNVTGLFVGQGPVVQVSNALGGKMVLKDEEYPALYTGPLVVLVNRYSASASEIF
AAAIQDYGRGVIVGDRTFGKGTVQSIVSIKRPFSMFTNQPDLGQLKLTVAKFYRISGGSTQHIGVLPDIVLPSMIDPEVV
GEDTYTSSLPWTTISRADYTPVGSVSRADISMLKSEFKARAAKDSQYQAYLADLATLNRIRNKKSVSLQEKNFETESKTL
KQIQDRWGDENLETGKKKKTDFIIQETAGIMDDLIDLKAQETDAPMLQKPAAQLIKAMPLGKK

Sequences:

>Translated_703_residues
MKSLRTALFPVFLIFSILTMSWGQSQAVPAKAAAPPALLAPTPEQMEASRHLAQYLIQNHYRKVPLNDSLSQQIFDRFLD
NIDNNRSYFTASDVERLRKEYGNRLDDDFITGNPEGGFAIYNQFLKRARQKMAFMMKALKTSTFDFTKPETLELERSKTA
PWSVDLAALQDQWRKELKYQYLNMKFTGEKGKSIKSALEKSFRNRLNLFNQQKPEDAFVAYMNAVTTSFDPHTDYFSPDM
YENFQIDMSRSLEGIGAKLQMENEYTVVNEIIPGGPAFKGNQLKKGDQIIGVGQGENGEIIDVVGWRINDVVKKIRGPKG
TVVRLKVLPASQANKGPARIIRIVRAKVDLQEQAAQKKIIIEKGKKIGVIVLPSFYLDFEGERQNKTNYTSTTRDVIKIL
NELNAAKVDGIILDLRDNGGGSLEEAVNVTGLFVGQGPVVQVSNALGGKMVLKDEEYPALYTGPLVVLVNRYSASASEIF
AAAIQDYGRGVIVGDRTFGKGTVQSIVSIKRPFSMFTNQPDLGQLKLTVAKFYRISGGSTQHIGVLPDIVLPSMIDPEVV
GEDTYTSSLPWTTISRADYTPVGSVSRADISMLKSEFKARAAKDSQYQAYLADLATLNRIRNKKSVSLQEKNFETESKTL
KQIQDRWGDENLETGKKKKTDFIIQETAGIMDDLIDLKAQETDAPMLQKPAAQLIKAMPLGKK
>Mature_703_residues
MKSLRTALFPVFLIFSILTMSWGQSQAVPAKAAAPPALLAPTPEQMEASRHLAQYLIQNHYRKVPLNDSLSQQIFDRFLD
NIDNNRSYFTASDVERLRKEYGNRLDDDFITGNPEGGFAIYNQFLKRARQKMAFMMKALKTSTFDFTKPETLELERSKTA
PWSVDLAALQDQWRKELKYQYLNMKFTGEKGKSIKSALEKSFRNRLNLFNQQKPEDAFVAYMNAVTTSFDPHTDYFSPDM
YENFQIDMSRSLEGIGAKLQMENEYTVVNEIIPGGPAFKGNQLKKGDQIIGVGQGENGEIIDVVGWRINDVVKKIRGPKG
TVVRLKVLPASQANKGPARIIRIVRAKVDLQEQAAQKKIIIEKGKKIGVIVLPSFYLDFEGERQNKTNYTSTTRDVIKIL
NELNAAKVDGIILDLRDNGGGSLEEAVNVTGLFVGQGPVVQVSNALGGKMVLKDEEYPALYTGPLVVLVNRYSASASEIF
AAAIQDYGRGVIVGDRTFGKGTVQSIVSIKRPFSMFTNQPDLGQLKLTVAKFYRISGGSTQHIGVLPDIVLPSMIDPEVV
GEDTYTSSLPWTTISRADYTPVGSVSRADISMLKSEFKARAAKDSQYQAYLADLATLNRIRNKKSVSLQEKNFETESKTL
KQIQDRWGDENLETGKKKKTDFIIQETAGIMDDLIDLKAQETDAPMLQKPAAQLIKAMPLGKK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=682, Percent_Identity=37.3900293255132, Blast_Score=422, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 78485; Mature: 78485

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50106 PDZ ; PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLRTALFPVFLIFSILTMSWGQSQAVPAKAAAPPALLAPTPEQMEASRHLAQYLIQNH
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHC
YRKVPLNDSLSQQIFDRFLDNIDNNRSYFTASDVERLRKEYGNRLDDDFITGNPEGGFAI
CEECCCCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
YNQFLKRARQKMAFMMKALKTSTFDFTKPETLELERSKTAPWSVDLAALQDQWRKELKYQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCEEHHHHHHHHHHHHHHHH
YLNMKFTGEKGKSIKSALEKSFRNRLNLFNQQKPEDAFVAYMNAVTTSFDPHTDYFSPDM
HCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
YENFQIDMSRSLEGIGAKLQMENEYTVVNEIIPGGPAFKGNQLKKGDQIIGVGQGENGEI
CCCEEEEHHHCCCCCCCEEEECCCEEEHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCE
IDVVGWRINDVVKKIRGPKGTVVRLKVLPASQANKGPARIIRIVRAKVDLQEQAAQKKII
EEEECCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHH
IEKGKKIGVIVLPSFYLDFEGERQNKTNYTSTTRDVIKILNELNAAKVDGIILDLRDNGG
EECCCEEEEEEECCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEECEEEEEEECCCC
GSLEEAVNVTGLFVGQGPVVQVSNALGGKMVLKDEEYPALYTGPLVVLVNRYSASASEIF
CCHHHHCCEEEEEECCCCEEEECCCCCCEEEEECCCCCEEECCCEEEEEECCCCCHHHHH
AAAIQDYGRGVIVGDRTFGKGTVQSIVSIKRPFSMFTNQPDLGQLKLTVAKFYRISGGST
HHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCHHHHCCCCCCCCEEEEEHHHHEECCCCC
QHIGVLPDIVLPSMIDPEVVGEDTYTSSLPWTTISRADYTPVGSVSRADISMLKSEFKAR
CCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHH
AAKDSQYQAYLADLATLNRIRNKKSVSLQEKNFETESKTLKQIQDRWGDENLETGKKKKT
HCCCHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCH
DFIIQETAGIMDDLIDLKAQETDAPMLQKPAAQLIKAMPLGKK
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKSLRTALFPVFLIFSILTMSWGQSQAVPAKAAAPPALLAPTPEQMEASRHLAQYLIQNH
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHC
YRKVPLNDSLSQQIFDRFLDNIDNNRSYFTASDVERLRKEYGNRLDDDFITGNPEGGFAI
CEECCCCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
YNQFLKRARQKMAFMMKALKTSTFDFTKPETLELERSKTAPWSVDLAALQDQWRKELKYQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCEEHHHHHHHHHHHHHHHH
YLNMKFTGEKGKSIKSALEKSFRNRLNLFNQQKPEDAFVAYMNAVTTSFDPHTDYFSPDM
HCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
YENFQIDMSRSLEGIGAKLQMENEYTVVNEIIPGGPAFKGNQLKKGDQIIGVGQGENGEI
CCCEEEEHHHCCCCCCCEEEECCCEEEHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCE
IDVVGWRINDVVKKIRGPKGTVVRLKVLPASQANKGPARIIRIVRAKVDLQEQAAQKKII
EEEECCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHH
IEKGKKIGVIVLPSFYLDFEGERQNKTNYTSTTRDVIKILNELNAAKVDGIILDLRDNGG
EECCCEEEEEEECCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEECEEEEEEECCCC
GSLEEAVNVTGLFVGQGPVVQVSNALGGKMVLKDEEYPALYTGPLVVLVNRYSASASEIF
CCHHHHCCEEEEEECCCCEEEECCCCCCEEEEECCCCCEEECCCEEEEEECCCCCHHHHH
AAAIQDYGRGVIVGDRTFGKGTVQSIVSIKRPFSMFTNQPDLGQLKLTVAKFYRISGGST
HHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCHHHHCCCCCCCCEEEEEHHHHEECCCCC
QHIGVLPDIVLPSMIDPEVVGEDTYTSSLPWTTISRADYTPVGSVSRADISMLKSEFKAR
CCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHH
AAKDSQYQAYLADLATLNRIRNKKSVSLQEKNFETESKTLKQIQDRWGDENLETGKKKKT
HCCCHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCH
DFIIQETAGIMDDLIDLKAQETDAPMLQKPAAQLIKAMPLGKK
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]