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The map label for this gene is htpG [H]

Identifier: 193212515

GI number: 193212515

Start: 930652

End: 932538

Strand: Direct

Name: htpG [H]

Synonym: Cpar_0853

Alternate gene names: 193212515

Gene position: 930652-932538 (Clockwise)

Preceding gene: 193212514

Following gene: 193212516

Centisome position: 40.65

GC content: 58.13

Gene sequence:

>1887_bases
ATGAGTGAACATACTTCCTCGGCAAAGCAATTTGAATACAAGGCCGAAATGAAACAGCTTCTGGACCTGATCGTCCATTC
GCTGTACACCCACCCTGAAATTTTTCTCCGCGAGCTGATCTCCAACGCCTCCGATGCGCTCGGCAAGGCGCGTTTCCGGA
TGCTTTCGTCCGACGAGGGCATTGACAAGTCGGGTGACCTGAAGATCACGATCACCGTCGATAAAGAGTCCGGCAACTTC
GTGATCGAGGACACCGGCATCGGCATGAGCGAGGAGGAGTTGATTGCCAACCTCGGCACGGTGGCCAAATCGGGTACGCT
CGGCTTCATGGAGTCGCTCAAGGCGCAGCAGAAAGAGGGGCAGCCGCTCGACGCAAACCTCATCGGCCAGTTCGGCGTCG
GCTTCTACTCGGTTTTCATGGTGACCGACGAGGTGACCGTCGAGACCAAAAGCGCCGAGGCCGGTTCGCAGGGGTGGCGC
TGGGTTTCGTCCGGTCAGGGCACCTACACCATCGAGCCGATCGAGCGCGAGGCTCGCGGTACGAAAATTTCGTTCACCCT
CAAGGAGGAGTTCAAGGAGTTTGCCGAGGAGTATCGCGTCGAGCAGATCATCAAGAAGTACTCCAACTTTGTGGAATATC
CGATCATGCTCGGCAGCCGCCAGATCAACAGCATGACCGCCCTCTGGCAGCGCCCGAAGAGCGAGCTGAAAGAGGAGGAG
GTCAACGAGTTCTACAAGTTCATCTCCAACGACTACAAGGAGCCGCTCGACTACCTGCACGTGTCGGTCGAGGGCGTGGT
AAGCTTCAAGGCGCTGCTTTTCATTCCTTCCGAAGCGCCGATGGAGCTGCTCTATCAGCAGGGTGCACTTGAAAAACGCG
GCCCGCAGCTCTACGTCAAAAAGGTCCTGATCCAGCACGAGTGCCGCGATCTTCTGCCGGAATATCTCCGTTTCGTGAGT
GGCGTGGTCGATACCGAAGACCTGTCGCTGAACGTTTCGCGGGAGCTGGTGCAGTCGAGCCCGGTGATGGCGAAGATTCG
CCAGATTCTTACCAGCAAGCTGCTCGGCTGGTTCGACACGCTCGCCAAGGAGCAGCCGGAAAAATTCCGCACCTTCTACA
AGGCGTTCGGCACCATCCTGAAAATCGGTCTCAACACCGATTTTACGAATCGTGACAAGCTCATCGAGCTGCTGCGCTTC
GAGACCACCAAGACTGGCGAGGGCGAATACGTCACGCTCAAGCAGTATGTGGGGCGCATGGCCGAGGGGCAGGAGGAGAT
CTACTACCACTCCGGCAACAGCCGCGCCCAGATGCTGGCGCACCCGAACCTCGAGTACTTCCGCAAGAAGGACATCGAGG
TGCTCTTGCTCTCCGACCCGGTCGATGTGTTCGTGATTCCCTCACTCTTCGAGTATGAGAAGAAGCCGCTCAAGTCGATC
GAGAAAGCCGAGATCGATGCCAGCACCATCGAGCCCGAGGCCGAAAAGCTCGGCGCGGAGGGAACCGTCGGCGTGATTTC
GCTTTTCAAAGAGGTGCTCGGTGAGCGCGTGGCCGACGTCGTAGAGTCCAAACGCCTCGTCAGCTCGCCCGTGACGCTGG
TGAGCGCCAAGGACGCGATGGACAGTCAGATGGAGAAGGTGATGAAGATGATGCAGCAGGATGCCGACATGCCTGGCGCC
AAGAAGGTGCTCGAAGTCAACACCGCGCACCCGATCATCAGGAACCTCGCCGGCAAGCAGGCGGTCGGTATGTCATCCGA
TCCGATCGTGCGTGCTGCTGTCATGCAGCTTTTCGACAGCGCCATGCTGCTTGAGGGTGATCTCGAGTCGGTTTCTGATT
ATGTGTCGCGCATGAACGAACTGGTCGAGGCGGCTACCAGAGCCTGA

Upstream 100 bases:

>100_bases
GCTCCTCACCCTTAAATTTACCCCGAAAATTCTCCCATTCGCCATCGTTCCAGGTCTTGGCCTGCAGGCGAAATCCGATT
AATTCCAAACGATGACTGCA

Downstream 100 bases:

>100_bases
TCGTTCCGCGTCTATTGTAAGTCCTTTGTCAGCCTGCTGCGACGTCCGCGGTAGGCTGATTTGTAATTCACTAACGCCAC
GCTATCCGTGAATACACTCA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MSEHTSSAKQFEYKAEMKQLLDLIVHSLYTHPEIFLRELISNASDALGKARFRMLSSDEGIDKSGDLKITITVDKESGNF
VIEDTGIGMSEEELIANLGTVAKSGTLGFMESLKAQQKEGQPLDANLIGQFGVGFYSVFMVTDEVTVETKSAEAGSQGWR
WVSSGQGTYTIEPIEREARGTKISFTLKEEFKEFAEEYRVEQIIKKYSNFVEYPIMLGSRQINSMTALWQRPKSELKEEE
VNEFYKFISNDYKEPLDYLHVSVEGVVSFKALLFIPSEAPMELLYQQGALEKRGPQLYVKKVLIQHECRDLLPEYLRFVS
GVVDTEDLSLNVSRELVQSSPVMAKIRQILTSKLLGWFDTLAKEQPEKFRTFYKAFGTILKIGLNTDFTNRDKLIELLRF
ETTKTGEGEYVTLKQYVGRMAEGQEEIYYHSGNSRAQMLAHPNLEYFRKKDIEVLLLSDPVDVFVIPSLFEYEKKPLKSI
EKAEIDASTIEPEAEKLGAEGTVGVISLFKEVLGERVADVVESKRLVSSPVTLVSAKDAMDSQMEKVMKMMQQDADMPGA
KKVLEVNTAHPIIRNLAGKQAVGMSSDPIVRAAVMQLFDSAMLLEGDLESVSDYVSRMNELVEAATRA

Sequences:

>Translated_628_residues
MSEHTSSAKQFEYKAEMKQLLDLIVHSLYTHPEIFLRELISNASDALGKARFRMLSSDEGIDKSGDLKITITVDKESGNF
VIEDTGIGMSEEELIANLGTVAKSGTLGFMESLKAQQKEGQPLDANLIGQFGVGFYSVFMVTDEVTVETKSAEAGSQGWR
WVSSGQGTYTIEPIEREARGTKISFTLKEEFKEFAEEYRVEQIIKKYSNFVEYPIMLGSRQINSMTALWQRPKSELKEEE
VNEFYKFISNDYKEPLDYLHVSVEGVVSFKALLFIPSEAPMELLYQQGALEKRGPQLYVKKVLIQHECRDLLPEYLRFVS
GVVDTEDLSLNVSRELVQSSPVMAKIRQILTSKLLGWFDTLAKEQPEKFRTFYKAFGTILKIGLNTDFTNRDKLIELLRF
ETTKTGEGEYVTLKQYVGRMAEGQEEIYYHSGNSRAQMLAHPNLEYFRKKDIEVLLLSDPVDVFVIPSLFEYEKKPLKSI
EKAEIDASTIEPEAEKLGAEGTVGVISLFKEVLGERVADVVESKRLVSSPVTLVSAKDAMDSQMEKVMKMMQQDADMPGA
KKVLEVNTAHPIIRNLAGKQAVGMSSDPIVRAAVMQLFDSAMLLEGDLESVSDYVSRMNELVEAATRA
>Mature_627_residues
SEHTSSAKQFEYKAEMKQLLDLIVHSLYTHPEIFLRELISNASDALGKARFRMLSSDEGIDKSGDLKITITVDKESGNFV
IEDTGIGMSEEELIANLGTVAKSGTLGFMESLKAQQKEGQPLDANLIGQFGVGFYSVFMVTDEVTVETKSAEAGSQGWRW
VSSGQGTYTIEPIEREARGTKISFTLKEEFKEFAEEYRVEQIIKKYSNFVEYPIMLGSRQINSMTALWQRPKSELKEEEV
NEFYKFISNDYKEPLDYLHVSVEGVVSFKALLFIPSEAPMELLYQQGALEKRGPQLYVKKVLIQHECRDLLPEYLRFVSG
VVDTEDLSLNVSRELVQSSPVMAKIRQILTSKLLGWFDTLAKEQPEKFRTFYKAFGTILKIGLNTDFTNRDKLIELLRFE
TTKTGEGEYVTLKQYVGRMAEGQEEIYYHSGNSRAQMLAHPNLEYFRKKDIEVLLLSDPVDVFVIPSLFEYEKKPLKSIE
KAEIDASTIEPEAEKLGAEGTVGVISLFKEVLGERVADVVESKRLVSSPVTLVSAKDAMDSQMEKVMKMMQQDADMPGAK
KVLEVNTAHPIIRNLAGKQAVGMSSDPIVRAAVMQLFDSAMLLEGDLESVSDYVSRMNELVEAATRA

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=634, Percent_Identity=34.7003154574132, Blast_Score=383, Evalue=1e-106,
Organism=Homo sapiens, GI4507677, Length=677, Percent_Identity=33.97341211226, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI20149594, Length=415, Percent_Identity=37.5903614457831, Blast_Score=257, Evalue=2e-68,
Organism=Homo sapiens, GI154146191, Length=414, Percent_Identity=35.7487922705314, Blast_Score=250, Evalue=3e-66,
Organism=Homo sapiens, GI153792590, Length=410, Percent_Identity=35.8536585365854, Blast_Score=248, Evalue=1e-65,
Organism=Escherichia coli, GI1786679, Length=628, Percent_Identity=41.0828025477707, Blast_Score=469, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI17559162, Length=680, Percent_Identity=36.7647058823529, Blast_Score=414, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17542208, Length=663, Percent_Identity=34.2383107088989, Blast_Score=347, Evalue=8e-96,
Organism=Caenorhabditis elegans, GI115535205, Length=644, Percent_Identity=34.0062111801242, Blast_Score=338, Evalue=6e-93,
Organism=Caenorhabditis elegans, GI115535167, Length=424, Percent_Identity=37.9716981132075, Blast_Score=278, Evalue=5e-75,
Organism=Saccharomyces cerevisiae, GI6323840, Length=411, Percent_Identity=37.2262773722628, Blast_Score=255, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6325016, Length=411, Percent_Identity=36.9829683698297, Blast_Score=253, Evalue=5e-68,
Organism=Drosophila melanogaster, GI24586016, Length=638, Percent_Identity=36.2068965517241, Blast_Score=378, Evalue=1e-105,
Organism=Drosophila melanogaster, GI21357739, Length=663, Percent_Identity=35.1432880844646, Blast_Score=344, Evalue=1e-94,
Organism=Drosophila melanogaster, GI17647529, Length=410, Percent_Identity=35.3658536585366, Blast_Score=251, Evalue=8e-67,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 70702; Mature: 70571

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHTSSAKQFEYKAEMKQLLDLIVHSLYTHPEIFLRELISNASDALGKARFRMLSSDEG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IDKSGDLKITITVDKESGNFVIEDTGIGMSEEELIANLGTVAKSGTLGFMESLKAQQKEG
CCCCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
QPLDANLIGQFGVGFYSVFMVTDEVTVETKSAEAGSQGWRWVSSGQGTYTIEPIEREARG
CCCCHHHHHHHHHHHHHHEEEECCEEEEECCCCCCCCCCEEEECCCCCEEECCHHHCCCC
TKISFTLKEEFKEFAEEYRVEQIIKKYSNFVEYPIMLGSRQINSMTALWQRPKSELKEEE
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHH
VNEFYKFISNDYKEPLDYLHVSVEGVVSFKALLFIPSEAPMELLYQQGALEKRGPQLYVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHEEEECCCCHHHHHHHHCCCHHCCHHHHHH
KVLIQHECRDLLPEYLRFVSGVVDTEDLSLNVSRELVQSSPVMAKIRQILTSKLLGWFDT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LAKEQPEKFRTFYKAFGTILKIGLNTDFTNRDKLIELLRFETTKTGEGEYVTLKQYVGRM
HHHCCHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEHHHHHHHH
AEGQEEIYYHSGNSRAQMLAHPNLEYFRKKDIEVLLLSDPVDVFVIPSLFEYEKKPLKSI
HCCCHHEEEECCCCCEEEEECCCHHHHHCCCCEEEEECCCCCEEECCHHHHHHHHHHHHH
EKAEIDASTIEPEAEKLGAEGTVGVISLFKEVLGERVADVVESKRLVSSPVTLVSAKDAM
HHHHCCHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHH
DSQMEKVMKMMQQDADMPGAKKVLEVNTAHPIIRNLAGKQAVGMSSDPIVRAAVMQLFDS
HHHHHHHHHHHHHCCCCCCCHHHEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
AMLLEGDLESVSDYVSRMNELVEAATRA
HHHHCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEHTSSAKQFEYKAEMKQLLDLIVHSLYTHPEIFLRELISNASDALGKARFRMLSSDEG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IDKSGDLKITITVDKESGNFVIEDTGIGMSEEELIANLGTVAKSGTLGFMESLKAQQKEG
CCCCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
QPLDANLIGQFGVGFYSVFMVTDEVTVETKSAEAGSQGWRWVSSGQGTYTIEPIEREARG
CCCCHHHHHHHHHHHHHHEEEECCEEEEECCCCCCCCCCEEEECCCCCEEECCHHHCCCC
TKISFTLKEEFKEFAEEYRVEQIIKKYSNFVEYPIMLGSRQINSMTALWQRPKSELKEEE
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHH
VNEFYKFISNDYKEPLDYLHVSVEGVVSFKALLFIPSEAPMELLYQQGALEKRGPQLYVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHEEEECCCCHHHHHHHHCCCHHCCHHHHHH
KVLIQHECRDLLPEYLRFVSGVVDTEDLSLNVSRELVQSSPVMAKIRQILTSKLLGWFDT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LAKEQPEKFRTFYKAFGTILKIGLNTDFTNRDKLIELLRFETTKTGEGEYVTLKQYVGRM
HHHCCHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEHHHHHHHH
AEGQEEIYYHSGNSRAQMLAHPNLEYFRKKDIEVLLLSDPVDVFVIPSLFEYEKKPLKSI
HCCCHHEEEECCCCCEEEEECCCHHHHHCCCCEEEEECCCCCEEECCHHHHHHHHHHHHH
EKAEIDASTIEPEAEKLGAEGTVGVISLFKEVLGERVADVVESKRLVSSPVTLVSAKDAM
HHHHCCHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHH
DSQMEKVMKMMQQDADMPGAKKVLEVNTAHPIIRNLAGKQAVGMSSDPIVRAAVMQLFDS
HHHHHHHHHHHHHCCCCCCCHHHEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
AMLLEGDLESVSDYVSRMNELVEAATRA
HHHHCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]