Click here to switch to the map view.

The map label for this gene is 193212514

Identifier: 193212514

GI number: 193212514

Start: 929628

End: 930497

Strand: Direct

Name: 193212514

Synonym: Cpar_0852

Alternate gene names: NA

Gene position: 929628-930497 (Clockwise)

Preceding gene: 193212513

Following gene: 193212515

Centisome position: 40.61

GC content: 60.0

Gene sequence:

>870_bases
ATGGCTGAAGTGAAAATGGGAAATCGGATGGTCGGCGACGGCCATCGGGTTTACGTTATTGCAGAGATTGGCATCAACCA
TAACGGTTCGCTCGAAGTGGCCAAAAAGCTGATCGATGGCGCCGCCCAGGCCGGTTGCGATGCGGTCAAGTTCCAGAAAC
GGACGCCGGAGCTGTGCGTTCCGATGGATCAGCGGCAGATCGAGCGCGATACTCCGTGGGGGCGCATGACCTACATGGAT
TATCGTTACAAGGTGGAGTTCGGTTTCGACGAGTATTCGGAAATCGACGAATACTGCCGTGAGAAAGGGATTGCCTGGTT
CGCTTCGTGCTGGGACGAAGAGGCGGTCGATTTCATGGAGCAGTTCAACCCGCCGTGCTACAAGGCGGCTTCGGCATCGC
TGACCGACCTGACGTTGCTTAAGAAGACTAGGGCGACTGGTCGTCCGCTGATGATTTCGACCGGCATGTCAACCATGGAG
GAGGTCGATGCGGCGGTTACAGAGCTGGGCAGGGAGAACCTGCTGATCGCGCACACCAACTCGACCTACCCCTGCCCGGT
CGAGGAGCTGAACCTTCGCATGATCCACACGCTTCAGCAGCGCTATCCCGACAATCCCATCGGCTACTCGGGCCACGAGG
TCGGGCTGGCTACGACGTGGGCGGCCGTGGCGCTTGGTGCAACCTTCATCGAGCGCCACGTGACGCTCGACCGCGCCATG
TGGGGCTCCGATCAGGCGGCGTCTGTGGAAATTTCCGGTATGGCGCGCCTGGTTGCCAACATCCGCGACATCGAAAAAGC
GCTCGGCGACGGCGTCAAGCGTGTCTACGAGGGCGAGGCGGCAGCACGCAAAAAGCTGCGCCGCGTTTGA

Upstream 100 bases:

>100_bases
AGCTTCATAATCGCACGTTCGTTCCAGAGAACTCATCATTCTTTATTATAAATCCGAGGGCGTGCAGTGCGCGCTTTCCA
CTATCTGATCGGTGTTATTT

Downstream 100 bases:

>100_bases
GCTTCCTTTCTTTTTTACTACCAAGTGCCCGTGTTTCGGGCACTTGCGTTATTTGCTCCTCACCCTTAAATTTACCCCGA
AAATTCTCCCATTCGCCATC

Product: N-acetylneuraminate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MAEVKMGNRMVGDGHRVYVIAEIGINHNGSLEVAKKLIDGAAQAGCDAVKFQKRTPELCVPMDQRQIERDTPWGRMTYMD
YRYKVEFGFDEYSEIDEYCREKGIAWFASCWDEEAVDFMEQFNPPCYKAASASLTDLTLLKKTRATGRPLMISTGMSTME
EVDAAVTELGRENLLIAHTNSTYPCPVEELNLRMIHTLQQRYPDNPIGYSGHEVGLATTWAAVALGATFIERHVTLDRAM
WGSDQAASVEISGMARLVANIRDIEKALGDGVKRVYEGEAAARKKLRRV

Sequences:

>Translated_289_residues
MAEVKMGNRMVGDGHRVYVIAEIGINHNGSLEVAKKLIDGAAQAGCDAVKFQKRTPELCVPMDQRQIERDTPWGRMTYMD
YRYKVEFGFDEYSEIDEYCREKGIAWFASCWDEEAVDFMEQFNPPCYKAASASLTDLTLLKKTRATGRPLMISTGMSTME
EVDAAVTELGRENLLIAHTNSTYPCPVEELNLRMIHTLQQRYPDNPIGYSGHEVGLATTWAAVALGATFIERHVTLDRAM
WGSDQAASVEISGMARLVANIRDIEKALGDGVKRVYEGEAAARKKLRRV
>Mature_288_residues
AEVKMGNRMVGDGHRVYVIAEIGINHNGSLEVAKKLIDGAAQAGCDAVKFQKRTPELCVPMDQRQIERDTPWGRMTYMDY
RYKVEFGFDEYSEIDEYCREKGIAWFASCWDEEAVDFMEQFNPPCYKAASASLTDLTLLKKTRATGRPLMISTGMSTMEE
VDAAVTELGRENLLIAHTNSTYPCPVEELNLRMIHTLQQRYPDNPIGYSGHEVGLATTWAAVALGATFIERHVTLDRAMW
GSDQAASVEISGMARLVANIRDIEKALGDGVKRVYEGEAAARKKLRRV

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=287, Percent_Identity=42.1602787456446, Blast_Score=218, Evalue=5e-57,
Organism=Drosophila melanogaster, GI21357081, Length=256, Percent_Identity=39.0625, Blast_Score=184, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 32369; Mature: 32238

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVKMGNRMVGDGHRVYVIAEIGINHNGSLEVAKKLIDGAAQAGCDAVKFQKRTPELCV
CCCCCCCCEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCC
PMDQRQIERDTPWGRMTYMDYRYKVEFGFDEYSEIDEYCREKGIAWFASCWDEEAVDFME
CCHHHHHHCCCCCCEEEEEEEEEEEEECCCHHHHHHHHHHHCCCEEEHHHCCHHHHHHHH
QFNPPCYKAASASLTDLTLLKKTRATGRPLMISTGMSTMEEVDAAVTELGRENLLIAHTN
HCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECC
STYPCPVEELNLRMIHTLQQRYPDNPIGYSGHEVGLATTWAAVALGATFIERHVTLDRAM
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WGSDQAASVEISGMARLVANIRDIEKALGDGVKRVYEGEAAARKKLRRV
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
AEVKMGNRMVGDGHRVYVIAEIGINHNGSLEVAKKLIDGAAQAGCDAVKFQKRTPELCV
CCCCCCCEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCC
PMDQRQIERDTPWGRMTYMDYRYKVEFGFDEYSEIDEYCREKGIAWFASCWDEEAVDFME
CCHHHHHHCCCCCCEEEEEEEEEEEEECCCHHHHHHHHHHHCCCEEEHHHCCHHHHHHHH
QFNPPCYKAASASLTDLTLLKKTRATGRPLMISTGMSTMEEVDAAVTELGRENLLIAHTN
HCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECC
STYPCPVEELNLRMIHTLQQRYPDNPIGYSGHEVGLATTWAAVALGATFIERHVTLDRAM
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WGSDQAASVEISGMARLVANIRDIEKALGDGVKRVYEGEAAARKKLRRV
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]