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The map label for this gene is kdsC [H]

Identifier: 193212513

GI number: 193212513

Start: 929019

End: 929537

Strand: Direct

Name: kdsC [H]

Synonym: Cpar_0851

Alternate gene names: 193212513

Gene position: 929019-929537 (Clockwise)

Preceding gene: 193212512

Following gene: 193212514

Centisome position: 40.58

GC content: 54.72

Gene sequence:

>519_bases
ATGATAGAACTCTCCCCGCAGGAACTGAAGTCGAGGGCTTCACGCATCAGACTTGTCCTTTCGGACAATGACGGGGTTTT
TACCGATAACGGCGTGTATTACTCGGAGAGAGGCGAGGAGTTCAAGCGCTTTTCCATTCGTGACGGCATGGGTGTCGAGC
GCCTTCGTGCTCATGGCATTGAAACCGGCATTATGACGGGCGAGGTCTCTCCAAGTCTGGTCAAACGGGCCGAGAAGCTT
CATATCACGAGCCTTTATCTTGGCGTCAAGGACAAATTGGCCCGACTGGAGGACGTGCTTCGTGATACCGGCCTTGACGT
TTCCGAAATTGCCTATATCGGCGATGATGTCAACGATCTCGGTATCATGAACGCTATCGCACCATTTGGCCTGGTGGCCT
GCCCCGGTGACGGGATGCATCTGGTGGAGCCGAGCGTTCACTATCGATGCACCGTTTTCGGCGGGCGTGGCGCGTTCCGG
GAGTATGCCGAATTACTCATTTCCCTGCGAGCTTCATAA

Upstream 100 bases:

>100_bases
CGTGTCTGTGGTGCTTTCGCGTGGCATCCTCAAGAGAAAAGTGATATATTTGCGGTTCATTTTTTGATCAACAGTTTTTT
ACGGAAAAGACCAGATTCTC

Downstream 100 bases:

>100_bases
TCGCACGTTCGTTCCAGAGAACTCATCATTCTTTATTATAAATCCGAGGGCGTGCAGTGCGCGCTTTCCACTATCTGATC
GGTGTTATTTATGGCTGAAG

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MIELSPQELKSRASRIRLVLSDNDGVFTDNGVYYSERGEEFKRFSIRDGMGVERLRAHGIETGIMTGEVSPSLVKRAEKL
HITSLYLGVKDKLARLEDVLRDTGLDVSEIAYIGDDVNDLGIMNAIAPFGLVACPGDGMHLVEPSVHYRCTVFGGRGAFR
EYAELLISLRAS

Sequences:

>Translated_172_residues
MIELSPQELKSRASRIRLVLSDNDGVFTDNGVYYSERGEEFKRFSIRDGMGVERLRAHGIETGIMTGEVSPSLVKRAEKL
HITSLYLGVKDKLARLEDVLRDTGLDVSEIAYIGDDVNDLGIMNAIAPFGLVACPGDGMHLVEPSVHYRCTVFGGRGAFR
EYAELLISLRAS
>Mature_172_residues
MIELSPQELKSRASRIRLVLSDNDGVFTDNGVYYSERGEEFKRFSIRDGMGVERLRAHGIETGIMTGEVSPSLVKRAEKL
HITSLYLGVKDKLARLEDVLRDTGLDVSEIAYIGDDVNDLGIMNAIAPFGLVACPGDGMHLVEPSVHYRCTVFGGRGAFR
EYAELLISLRAS

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=160, Percent_Identity=29.375, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI2367202, Length=157, Percent_Identity=36.3057324840764, Blast_Score=100, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 18992; Mature: 18992

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELSPQELKSRASRIRLVLSDNDGVFTDNGVYYSERGEEFKRFSIRDGMGVERLRAHGI
CCCCCHHHHHHHHHHEEEEEECCCCEEECCCEEECCCCCHHHHHHCCCCCCHHHHHHCCC
ETGIMTGEVSPSLVKRAEKLHITSLYLGVKDKLARLEDVLRDTGLDVSEIAYIGDDVNDL
CCCEEECCCCHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHH
GIMNAIAPFGLVACPGDGMHLVEPSVHYRCTVFGGRGAFREYAELLISLRAS
HHHHHHHCCCEEECCCCCCEEECCCCEEEEEEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIELSPQELKSRASRIRLVLSDNDGVFTDNGVYYSERGEEFKRFSIRDGMGVERLRAHGI
CCCCCHHHHHHHHHHEEEEEECCCCEEECCCEEECCCCCHHHHHHCCCCCCHHHHHHCCC
ETGIMTGEVSPSLVKRAEKLHITSLYLGVKDKLARLEDVLRDTGLDVSEIAYIGDDVNDL
CCCEEECCCCHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHH
GIMNAIAPFGLVACPGDGMHLVEPSVHYRCTVFGGRGAFREYAELLISLRAS
HHHHHHHCCCEEECCCCCCEEECCCCEEEEEEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]