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The map label for this gene is ppa [H]

Identifier: 193212512

GI number: 193212512

Start: 927960

End: 928493

Strand: Direct

Name: ppa [H]

Synonym: Cpar_0850

Alternate gene names: 193212512

Gene position: 927960-928493 (Clockwise)

Preceding gene: 193212511

Following gene: 193212513

Centisome position: 40.54

GC content: 50.75

Gene sequence:

>534_bases
ATGAATTTTAACCCGTGGCACCACGTCGAAATCGGTGAAGAGTGTCCGAATGTCGTTAATGCGATCATCGAAATTGCCAA
AGACAGCAAAACCAAGTACGAGCTGGACAAAAAGACCGGCATGCTGAAGCTCGACCGCGTGTTGTTCTCCTCCGTTCTTT
ATCCCGAAAATTATGGCTTTATCCCCAAAACCCTCGGTGAAGACCATGATCCGCTCGACATCGTCGTTGTTTCGCAGTGC
TCCATTGTGCCGATGTGCATGGTGAAGGCCAGAGTGATCGGCGTGATGCGCATGATCGACCATGGCGAGGGCGACGACAA
GATCATCGCGGTGGCTGAAGACGATATGAGCGTCAGCGGCATCAACGATATTGGTGATCTCGGCAAGCACTTCAAGATGG
AGCTTCAGCACTTCTTCGAAGAGTACAAGGCGCTCGAAAACAAAACTGTTCTGGTCGAGAATTTCCAGGACGCTGCAACC
GCAAAGCGGATTCTGCTCGAATCGATCGATAGATACAGCAAGACCTTCGTCTGA

Upstream 100 bases:

>100_bases
CAGCTGCGAGGGCTGCCCCTACTTTTTTCTGGAAGGTTTGAAAAAAAATTCTATTTTGGCTCACCTTCCATCAACACCAT
CAAGATAAGGACAGTCAACT

Downstream 100 bases:

>100_bases
GGGGCCTCGCATCGCGATTGTCCATTTTTCAGGGCGGCATAAAACCTGTGTTTTATGCCGCCTTTTTGATTGCATCATCC
GATATTGAGACTCGATCAGT

Product: Inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MNFNPWHHVEIGEECPNVVNAIIEIAKDSKTKYELDKKTGMLKLDRVLFSSVLYPENYGFIPKTLGEDHDPLDIVVVSQC
SIVPMCMVKARVIGVMRMIDHGEGDDKIIAVAEDDMSVSGINDIGDLGKHFKMELQHFFEEYKALENKTVLVENFQDAAT
AKRILLESIDRYSKTFV

Sequences:

>Translated_177_residues
MNFNPWHHVEIGEECPNVVNAIIEIAKDSKTKYELDKKTGMLKLDRVLFSSVLYPENYGFIPKTLGEDHDPLDIVVVSQC
SIVPMCMVKARVIGVMRMIDHGEGDDKIIAVAEDDMSVSGINDIGDLGKHFKMELQHFFEEYKALENKTVLVENFQDAAT
AKRILLESIDRYSKTFV
>Mature_177_residues
MNFNPWHHVEIGEECPNVVNAIIEIAKDSKTKYELDKKTGMLKLDRVLFSSVLYPENYGFIPKTLGEDHDPLDIVVVSQC
SIVPMCMVKARVIGVMRMIDHGEGDDKIIAVAEDDMSVSGINDIGDLGKHFKMELQHFFEEYKALENKTVLVENFQDAAT
AKRILLESIDRYSKTFV

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Homo sapiens, GI11056044, Length=179, Percent_Identity=30.1675977653631, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1790673, Length=168, Percent_Identity=36.3095238095238, Blast_Score=112, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71984895, Length=205, Percent_Identity=24.8780487804878, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71984880, Length=205, Percent_Identity=24.8780487804878, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71984889, Length=205, Percent_Identity=24.8780487804878, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71984883, Length=205, Percent_Identity=24.8780487804878, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319483, Length=172, Percent_Identity=28.4883720930233, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 20080; Mature: 20080

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFNPWHHVEIGEECPNVVNAIIEIAKDSKTKYELDKKTGMLKLDRVLFSSVLYPENYGF
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
IPKTLGEDHDPLDIVVVSQCSIVPMCMVKARVIGVMRMIDHGEGDDKIIAVAEDDMSVSG
CCHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
INDIGDLGKHFKMELQHFFEEYKALENKTVLVENFQDAATAKRILLESIDRYSKTFV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFNPWHHVEIGEECPNVVNAIIEIAKDSKTKYELDKKTGMLKLDRVLFSSVLYPENYGF
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
IPKTLGEDHDPLDIVVVSQCSIVPMCMVKARVIGVMRMIDHGEGDDKIIAVAEDDMSVSG
CCHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
INDIGDLGKHFKMELQHFFEEYKALENKTVLVENFQDAATAKRILLESIDRYSKTFV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA