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The map label for this gene is xerC

Identifier: 193212222

GI number: 193212222

Start: 594109

End: 595119

Strand: Direct

Name: xerC

Synonym: Cpar_0553

Alternate gene names: 193212222

Gene position: 594109-595119 (Clockwise)

Preceding gene: 193212221

Following gene: 193212223

Centisome position: 25.95

GC content: 53.02

Gene sequence:

>1011_bases
ATGACCATAAACCGTTCAAGGCAGCCGGAAGATCACGAAGTGGCAAGGTGCCGGTGGCTTGAACCTTTTCTTTCTCATCT
GCAGGCGGCCAGAAACGTTTCACCCAAAACGGTCACCGCTTACCGATGCGATCTTCTCCAGTATTTTTCCTTCCTGAAAG
AACAGGCCGGCCTTGACAGGCTTGAAGCTGTTGAACCTGAACGGGTGGAGGTTGCTGATGTCAGGCTCTTTATGGGTCAC
TTGCTCGACAAGGGGATACAGCCTCGCTCGATTGCCCGAAAGCTCGCCTCGGTCAAAAGCTTCTACCGTTTTCTCCTCGA
AACCGGAAGGATCAGTTCGTCGCCGCTCTCACTGGTCGTTACGCCACGTCTGGACAAAAAAGTGCCTCGCTTTGTAAGCG
AAGAGGAGGCCCGCCAGCTTTTCAGGCGTTTCGAATCGCAGGAGGATAATGCGGCTTTACAGGGTGATGGAAAAAAGGCT
GAAGTCCGGCAGTTTGAGACTTTTCGGGATCGTGCCGTGCTTGAGGTGCTCTACGGATGCGGCCTTCGCTTGTCGGAGCT
GATCGCGCTTGAACGGGCCGATGTCGACTTGGTGCACGGCTTTCTCAAAGTGACCGGAAAAGGGCGCAAGCAGCGTATCG
TGCCGCTTGGCGAACCCGCCGTGGAGGCGCTCAGAAAGTATTTTGAAGTCAGACGAAACTTCTTTAGAATACCTTTAGAG
AGGACAGGTGAATCGTCCAGGGTTTTCGTCACATCAAGAGGAAGACAGCTCTATCCTATGCTTGTCCAGAGAATGACAAA
GAGGTATCTCACCCCGGTTTCCGAGTCGGAAAAGAAGAATCCCCATATTCTCCGACACAGTTTTGCCACACATATGCTCA
ACGGCGGCGCAGATCTGAAAAGCGTCAGCGAAATGCTCGGTCACAGTAGCCTGACGACCACGGAGTTGTACACGCATGTG
ACGTTCAGCAGGCTGAAGGAGATTTACGATAAAGCCCATCCAGGGGCTTGA

Upstream 100 bases:

>100_bases
CCGCTGTTCAACAACTTTCTTGTCAGGGACCAGCGGCTCTATTACATCAAAGAGAGAGAAATGCTCGTCAGCATCGATCT
CTCATGAACGTAACCTTTTC

Downstream 100 bases:

>100_bases
TCTCTGTCGTTCGCCGAAAGTTGTTGACAAGGCAGAATTGATGCCGGTTTCGTTCTTTGCAAGTTTATAATTCTTTAATG
GAGGTAAGTATGACTAAATC

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTINRSRQPEDHEVARCRWLEPFLSHLQAARNVSPKTVTAYRCDLLQYFSFLKEQAGLDRLEAVEPERVEVADVRLFMGH
LLDKGIQPRSIARKLASVKSFYRFLLETGRISSSPLSLVVTPRLDKKVPRFVSEEEARQLFRRFESQEDNAALQGDGKKA
EVRQFETFRDRAVLEVLYGCGLRLSELIALERADVDLVHGFLKVTGKGRKQRIVPLGEPAVEALRKYFEVRRNFFRIPLE
RTGESSRVFVTSRGRQLYPMLVQRMTKRYLTPVSESEKKNPHILRHSFATHMLNGGADLKSVSEMLGHSSLTTTELYTHV
TFSRLKEIYDKAHPGA

Sequences:

>Translated_336_residues
MTINRSRQPEDHEVARCRWLEPFLSHLQAARNVSPKTVTAYRCDLLQYFSFLKEQAGLDRLEAVEPERVEVADVRLFMGH
LLDKGIQPRSIARKLASVKSFYRFLLETGRISSSPLSLVVTPRLDKKVPRFVSEEEARQLFRRFESQEDNAALQGDGKKA
EVRQFETFRDRAVLEVLYGCGLRLSELIALERADVDLVHGFLKVTGKGRKQRIVPLGEPAVEALRKYFEVRRNFFRIPLE
RTGESSRVFVTSRGRQLYPMLVQRMTKRYLTPVSESEKKNPHILRHSFATHMLNGGADLKSVSEMLGHSSLTTTELYTHV
TFSRLKEIYDKAHPGA
>Mature_335_residues
TINRSRQPEDHEVARCRWLEPFLSHLQAARNVSPKTVTAYRCDLLQYFSFLKEQAGLDRLEAVEPERVEVADVRLFMGHL
LDKGIQPRSIARKLASVKSFYRFLLETGRISSSPLSLVVTPRLDKKVPRFVSEEEARQLFRRFESQEDNAALQGDGKKAE
VRQFETFRDRAVLEVLYGCGLRLSELIALERADVDLVHGFLKVTGKGRKQRIVPLGEPAVEALRKYFEVRRNFFRIPLER
TGESSRVFVTSRGRQLYPMLVQRMTKRYLTPVSESEKKNPHILRHSFATHMLNGGADLKSVSEMLGHSSLTTTELYTHVT
FSRLKEIYDKAHPGA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=319, Percent_Identity=35.423197492163, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1790244, Length=317, Percent_Identity=31.5457413249211, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_CHLP8 (B3QM22)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001998175.1
- ProteinModelPortal:   B3QM22
- GeneID:   6419467
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_0553
- HOGENOM:   HBG727654
- OMA:   PMLVQRM
- ProtClustDB:   CLSK637863
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 38632; Mature: 38501

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: ACT_SITE 183-183 ACT_SITE 207-207 ACT_SITE 282-282 ACT_SITE 285-285 ACT_SITE 308-308 ACT_SITE 317-317

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTINRSRQPEDHEVARCRWLEPFLSHLQAARNVSPKTVTAYRCDLLQYFSFLKEQAGLDR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHH
LEAVEPERVEVADVRLFMGHLLDKGIQPRSIARKLASVKSFYRFLLETGRISSSPLSLVV
HHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
TPRLDKKVPRFVSEEEARQLFRRFESQEDNAALQGDGKKAEVRQFETFRDRAVLEVLYGC
CCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GLRLSELIALERADVDLVHGFLKVTGKGRKQRIVPLGEPAVEALRKYFEVRRNFFRIPLE
CCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCHH
RTGESSRVFVTSRGRQLYPMLVQRMTKRYLTPVSESEKKNPHILRHSFATHMLNGGADLK
HCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHH
SVSEMLGHSSLTTTELYTHVTFSRLKEIYDKAHPGA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TINRSRQPEDHEVARCRWLEPFLSHLQAARNVSPKTVTAYRCDLLQYFSFLKEQAGLDR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHH
LEAVEPERVEVADVRLFMGHLLDKGIQPRSIARKLASVKSFYRFLLETGRISSSPLSLVV
HHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
TPRLDKKVPRFVSEEEARQLFRRFESQEDNAALQGDGKKAEVRQFETFRDRAVLEVLYGC
CCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GLRLSELIALERADVDLVHGFLKVTGKGRKQRIVPLGEPAVEALRKYFEVRRNFFRIPLE
CCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCHH
RTGESSRVFVTSRGRQLYPMLVQRMTKRYLTPVSESEKKNPHILRHSFATHMLNGGADLK
HCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHH
SVSEMLGHSSLTTTELYTHVTFSRLKEIYDKAHPGA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA