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The map label for this gene is pab [H]

Identifier: 193212149

GI number: 193212149

Start: 511742

End: 513562

Strand: Direct

Name: pab [H]

Synonym: Cpar_0480

Alternate gene names: 193212149

Gene position: 511742-513562 (Clockwise)

Preceding gene: 193212148

Following gene: 193212150

Centisome position: 22.35

GC content: 60.35

Gene sequence:

>1821_bases
ATGGCGCTGTACGATGAGCTTTCCAGACCGGGTTCGCTCTGGTTTGAATCCACCTGTCCGGACGCGCGCTACGGCGAATC
CCTCCTTTTTACCGATCCGGTCGAAATCCTGACGCTCCATTCCGGTGATGACATCCGGGCCTGGTTTGAAAGCCTTGAGT
CGCGGCTTGAAAAAGGGTATGCGCTGGCCGGATGGCTCGGTTACGAAGCGGGCTATCTGCTTGATTCGGCGCTTGACAGG
TGCGCCTGGCCTGACGAGGGGCGGACGCTGCTCGGATGGTTCGGTGTCTATCGTGCTCCGAAGCGGATCGGCCGTGAGCA
GATCGATGCAGCGGACGAGCAGGCGGCCGTGCGCAAGTGCGCGGTTTCCGGGTTCGGCTTCGAGTTTGACGAAGCTGAGT
ATTGCCAGCGCATCGACCGGCTCAAAGATGAAATTGCAGCGGGCAACGTCTATCAGGTCAACTTTACCGGGCGTTGCGGT
TTCACGTTTGACGGCTCTCCGGAGGCGCTCTACGTTGCCATGAAGCGCCGCCAACCCTCGCCGTGGTCGGCCATGCTCAA
CACCGGCGACCGGCTGGTGCTCTCCTTTTCGCCCGAGCTGTTTTTTGTTCGTGAGGGGCGCTTGATCGAAACCATGCCGA
TGAAGGGTACCGCGCCGAGAATGACAAGCGCTGAGGAGGATCGTGCCGCTCGTGAAGGGTTGGCGAAGTGCGAAAAGAAC
CGGGCGGAGAACCTGATGATTGTCGATCTTCTGCGCAACGATCTTGGGCGCATCTGCGAGACCGGGTCGGTACAGGCATC
CGACCTGTTCGAGACGCAGACCTATCCGACCCTGCACCAGATGGTTTCGACCATTCGTGGCGAGCTTCGCGACGAGACCC
GCCTGCACGACCTGTTCCGGGCGCTGTTCCCCTGCGGTTCGGTGACCGGTGCGCCGAAAGTGCGGGCGATGAAGCTGATC
CGCGAGCTGGAACGCAGCCCGCGAGGCGTCTATACCGGCGCGGTCGGTTTCATGCTGCCGGGCGGGCGAACGGCCTTCAA
CGTGGCGATCCGAACTATCGAGCTACAGGGACGGCGCGGCGTGTATGGCACTGGCAGCGGTATCGTCTGGGACTCGGAGC
CGCAGCAGGAGTTCCGGGAGTGTATGCTCAAGACCGAGATTCTCTCCGGACTTGTTCCATCATCCCCTGGCATTTTCGAG
ACTATCCAGTGGAATGGATTCGACTATCTGCTGCTCGACGACCATCTCGACCGGCTTTTTGCATCGGCACAAGCGCTTGG
GATCAAGGTTGACCAGAGTGCCGTGCTTGATGAGCTGGATGCAAAGGCGGAGGAGCTTCGGGCGCTTGGCGGTCGTCACC
GCGTCAGATTGACGCTTGGCCACAACGGCGACGTGCTGGTGGAATCGGAGCCATTTACGCTCGACTTGTCCGGCAACTCT
GTCCGGGTGTGCATCGCCAGCGAACGGGTCGATTCCGCCGATTCGCTGCTTCATTACAAGACGACGGCCCGTAATCGCTA
CGATCAGGCGCTGATGCAGGCGATGGGCAAAGGATTTGGCGAGGTGCTGTTCCTGAACGAGCGTGGAGAGTTGACCGAAG
GGGCCATCAGCAATGTGCTGCTTCGGATCGACGGTAGCTGGTTTACACCACCCGAATCATCCGGGCTGCTCAACGGCGTG
TTCCGGCGTTACCTCTTGCGCACTCGTCCCTGGATCAAAGAACGATCGCTTACCCTCGACGATCTTCGCCGTGCCGAGAT
CGTGTTGATCTGCAATTCTCTGCGGGGGATGCGCCGTGCCGAGGTCGATATTTCCGAATGA

Upstream 100 bases:

>100_bases
GCTATGAACCCGACATCGAGCTGTGGGCGGTGAGCGGCCACAAGGAGTGGCTCGAAGAGGTGCTTGGCAAGCCGATCGTG
ATCGAGGCTTCGCTGCAGTG

Downstream 100 bases:

>100_bases
TCGCTTCTCAGAGGTTGAAGCGCAACCAGCAGCGCCGTATATTGATACCAGAAATCGTTTTAGCAACCGCTAACCTCCTC
CAGCCATGAGAGACCACACG

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: P-aminobenzoic acid synthase; PABA synthase [H]

Number of amino acids: Translated: 606; Mature: 605

Protein sequence:

>606_residues
MALYDELSRPGSLWFESTCPDARYGESLLFTDPVEILTLHSGDDIRAWFESLESRLEKGYALAGWLGYEAGYLLDSALDR
CAWPDEGRTLLGWFGVYRAPKRIGREQIDAADEQAAVRKCAVSGFGFEFDEAEYCQRIDRLKDEIAAGNVYQVNFTGRCG
FTFDGSPEALYVAMKRRQPSPWSAMLNTGDRLVLSFSPELFFVREGRLIETMPMKGTAPRMTSAEEDRAAREGLAKCEKN
RAENLMIVDLLRNDLGRICETGSVQASDLFETQTYPTLHQMVSTIRGELRDETRLHDLFRALFPCGSVTGAPKVRAMKLI
RELERSPRGVYTGAVGFMLPGGRTAFNVAIRTIELQGRRGVYGTGSGIVWDSEPQQEFRECMLKTEILSGLVPSSPGIFE
TIQWNGFDYLLLDDHLDRLFASAQALGIKVDQSAVLDELDAKAEELRALGGRHRVRLTLGHNGDVLVESEPFTLDLSGNS
VRVCIASERVDSADSLLHYKTTARNRYDQALMQAMGKGFGEVLFLNERGELTEGAISNVLLRIDGSWFTPPESSGLLNGV
FRRYLLRTRPWIKERSLTLDDLRRAEIVLICNSLRGMRRAEVDISE

Sequences:

>Translated_606_residues
MALYDELSRPGSLWFESTCPDARYGESLLFTDPVEILTLHSGDDIRAWFESLESRLEKGYALAGWLGYEAGYLLDSALDR
CAWPDEGRTLLGWFGVYRAPKRIGREQIDAADEQAAVRKCAVSGFGFEFDEAEYCQRIDRLKDEIAAGNVYQVNFTGRCG
FTFDGSPEALYVAMKRRQPSPWSAMLNTGDRLVLSFSPELFFVREGRLIETMPMKGTAPRMTSAEEDRAAREGLAKCEKN
RAENLMIVDLLRNDLGRICETGSVQASDLFETQTYPTLHQMVSTIRGELRDETRLHDLFRALFPCGSVTGAPKVRAMKLI
RELERSPRGVYTGAVGFMLPGGRTAFNVAIRTIELQGRRGVYGTGSGIVWDSEPQQEFRECMLKTEILSGLVPSSPGIFE
TIQWNGFDYLLLDDHLDRLFASAQALGIKVDQSAVLDELDAKAEELRALGGRHRVRLTLGHNGDVLVESEPFTLDLSGNS
VRVCIASERVDSADSLLHYKTTARNRYDQALMQAMGKGFGEVLFLNERGELTEGAISNVLLRIDGSWFTPPESSGLLNGV
FRRYLLRTRPWIKERSLTLDDLRRAEIVLICNSLRGMRRAEVDISE
>Mature_605_residues
ALYDELSRPGSLWFESTCPDARYGESLLFTDPVEILTLHSGDDIRAWFESLESRLEKGYALAGWLGYEAGYLLDSALDRC
AWPDEGRTLLGWFGVYRAPKRIGREQIDAADEQAAVRKCAVSGFGFEFDEAEYCQRIDRLKDEIAAGNVYQVNFTGRCGF
TFDGSPEALYVAMKRRQPSPWSAMLNTGDRLVLSFSPELFFVREGRLIETMPMKGTAPRMTSAEEDRAAREGLAKCEKNR
AENLMIVDLLRNDLGRICETGSVQASDLFETQTYPTLHQMVSTIRGELRDETRLHDLFRALFPCGSVTGAPKVRAMKLIR
ELERSPRGVYTGAVGFMLPGGRTAFNVAIRTIELQGRRGVYGTGSGIVWDSEPQQEFRECMLKTEILSGLVPSSPGIFET
IQWNGFDYLLLDDHLDRLFASAQALGIKVDQSAVLDELDAKAEELRALGGRHRVRLTLGHNGDVLVESEPFTLDLSGNSV
RVCIASERVDSADSLLHYKTTARNRYDQALMQAMGKGFGEVLFLNERGELTEGAISNVLLRIDGSWFTPPESSGLLNGVF
RRYLLRTRPWIKERSLTLDDLRRAEIVLICNSLRGMRRAEVDISE

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=253, Percent_Identity=37.9446640316205, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI1787518, Length=248, Percent_Identity=36.6935483870968, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1786809, Length=193, Percent_Identity=28.4974093264249, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=253, Percent_Identity=36.7588932806324, Blast_Score=156, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6324361, Length=269, Percent_Identity=26.0223048327138, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR005802
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 67931; Mature: 67800

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALYDELSRPGSLWFESTCPDARYGESLLFTDPVEILTLHSGDDIRAWFESLESRLEKGY
CCCHHHHCCCCCEEECCCCCCCCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHHHHCCC
ALAGWLGYEAGYLLDSALDRCAWPDEGRTLLGWFGVYRAPKRIGREQIDAADEQAAVRKC
EEEEEHHCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCHHHHCHHHHCCCHHHHHHHHH
AVSGFGFEFDEAEYCQRIDRLKDEIAAGNVYQVNFTGRCGFTFDGSPEALYVAMKRRQPS
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECEECCEECCCCCEEEEEECCCCCC
PWSAMLNTGDRLVLSFSPELFFVREGRLIETMPMKGTAPRMTSAEEDRAAREGLAKCEKN
CHHHHHCCCCEEEEEECCCEEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RAENLMIVDLLRNDLGRICETGSVQASDLFETQTYPTLHQMVSTIRGELRDETRLHDLFR
CCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALFPCGSVTGAPKVRAMKLIRELERSPRGVYTGAVGFMLPGGRTAFNVAIRTIELQGRRG
HHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCEEECCCCCEEEEEEEEEEEECCCCC
VYGTGSGIVWDSEPQQEFRECMLKTEILSGLVPSSPGIFETIQWNGFDYLLLDDHLDRLF
CCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEEHHHHHHHH
ASAQALGIKVDQSAVLDELDAKAEELRALGGRHRVRLTLGHNGDVLVESEPFTLDLSGNS
HHHHHHEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCEEEEECCCE
VRVCIASERVDSADSLLHYKTTARNRYDQALMQAMGKGFGEVLFLNERGELTEGAISNVL
EEEEEECCCCCCHHHHEEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHCEEE
LRIDGSWFTPPESSGLLNGVFRRYLLRTRPWIKERSLTLDDLRRAEIVLICNSLRGMRRA
EEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCHHHHCCCEEEEEECHHCCCEEC
EVDISE
CCCCCC
>Mature Secondary Structure 
ALYDELSRPGSLWFESTCPDARYGESLLFTDPVEILTLHSGDDIRAWFESLESRLEKGY
CCHHHHCCCCCEEECCCCCCCCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHHHHCCC
ALAGWLGYEAGYLLDSALDRCAWPDEGRTLLGWFGVYRAPKRIGREQIDAADEQAAVRKC
EEEEEHHCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCHHHHCHHHHCCCHHHHHHHHH
AVSGFGFEFDEAEYCQRIDRLKDEIAAGNVYQVNFTGRCGFTFDGSPEALYVAMKRRQPS
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECEECCEECCCCCEEEEEECCCCCC
PWSAMLNTGDRLVLSFSPELFFVREGRLIETMPMKGTAPRMTSAEEDRAAREGLAKCEKN
CHHHHHCCCCEEEEEECCCEEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RAENLMIVDLLRNDLGRICETGSVQASDLFETQTYPTLHQMVSTIRGELRDETRLHDLFR
CCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALFPCGSVTGAPKVRAMKLIRELERSPRGVYTGAVGFMLPGGRTAFNVAIRTIELQGRRG
HHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCEEECCCCCEEEEEEEEEEEECCCCC
VYGTGSGIVWDSEPQQEFRECMLKTEILSGLVPSSPGIFETIQWNGFDYLLLDDHLDRLF
CCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEEHHHHHHHH
ASAQALGIKVDQSAVLDELDAKAEELRALGGRHRVRLTLGHNGDVLVESEPFTLDLSGNS
HHHHHHEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCEEEEECCCE
VRVCIASERVDSADSLLHYKTTARNRYDQALMQAMGKGFGEVLFLNERGELTEGAISNVL
EEEEEECCCCCCHHHHEEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHCEEE
LRIDGSWFTPPESSGLLNGVFRRYLLRTRPWIKERSLTLDDLRRAEIVLICNSLRGMRRA
EEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCHHHHCCCEEEEEECHHCCCEEC
EVDISE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]