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The map label for this gene is pyrH [H]

Identifier: 193212096

GI number: 193212096

Start: 461574

End: 462293

Strand: Direct

Name: pyrH [H]

Synonym: Cpar_0427

Alternate gene names: 193212096

Gene position: 461574-462293 (Clockwise)

Preceding gene: 193212095

Following gene: 193212099

Centisome position: 20.16

GC content: 52.5

Gene sequence:

>720_bases
ATGCTAAAGTACAGGAGAATCCTGTTCAAGATCAGCGGCGAGTCGCTTGCAGGAGAGAGTGGATACGGAATTGATGCCGG
TGTACTTGTAAAGTTTGCCGAAGAGATAAAGGAGGCCAGCGACCTCGGTGCTGAAATCGCACTGGTCATCGGTGGTGGCA
ATATCTTCAGGGGTTTGTCGAAAGCAGCCGCTTCGATGGACCGTGTTCAGGCCGATTATATGGGGATGCTTGCTACCGTC
ATCAACTCGCTTGCCCTTCAGGACGCTCTCGAACGGCAGGGAATTTACACTCGCCTGCTGACAGCTATCAAGATGGAGCA
GATCGCCGAGCCGTTCATAAGACGCCGTGCGGTAAGGCATCTCGAAAAAGGACGAGTTGTCATTTTTGGGGCAGGCACGG
GTAACCCCTATTTTACCACCGATACGGCGGCCTCTCTGCGAGCTATCGAAATCGAAGCCGACGTCATCATCAAGGGCACC
AGGGTCGAAGGTGTGTATGATTCAGATCCGGAGAAAAATCCCGATGCGGAGTTCTTCCCGAGAATCTCCTATTTCGACGT
GATCAGGAAAAATCTCAGGGTAATGGATATGACCGCCATCACGCTTTGCCGCGAAAACACCCTTCCAATTGTGGTGATGA
ACATGAACACGAAAGGCAATTTCACCCGCTTGCTCAAAGGCGAGCCGATCGGTACGCTCGTGCATATCGGGGAGGAGTAG

Upstream 100 bases:

>100_bases
TGAAAAAAGCCTCGTTGATACGAGGCTTTTTTTTTTGCTTATTACTTATTAAGAGCAGTTAAGTTTGTCGCTTAGCCAAC
CAGTAGAAGGAGATGCAGGT

Downstream 100 bases:

>100_bases
CAGTTGATACTGGATAATTGACAGTTGATAATTGAAAAAGGCGATCCAGATAAATCAGGGTCGCCTTTTTGCATTGGGGG
GAGCAGGTGGGTCGGTCTGA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MLKYRRILFKISGESLAGESGYGIDAGVLVKFAEEIKEASDLGAEIALVIGGGNIFRGLSKAAASMDRVQADYMGMLATV
INSLALQDALERQGIYTRLLTAIKMEQIAEPFIRRRAVRHLEKGRVVIFGAGTGNPYFTTDTAASLRAIEIEADVIIKGT
RVEGVYDSDPEKNPDAEFFPRISYFDVIRKNLRVMDMTAITLCRENTLPIVVMNMNTKGNFTRLLKGEPIGTLVHIGEE

Sequences:

>Translated_239_residues
MLKYRRILFKISGESLAGESGYGIDAGVLVKFAEEIKEASDLGAEIALVIGGGNIFRGLSKAAASMDRVQADYMGMLATV
INSLALQDALERQGIYTRLLTAIKMEQIAEPFIRRRAVRHLEKGRVVIFGAGTGNPYFTTDTAASLRAIEIEADVIIKGT
RVEGVYDSDPEKNPDAEFFPRISYFDVIRKNLRVMDMTAITLCRENTLPIVVMNMNTKGNFTRLLKGEPIGTLVHIGEE
>Mature_239_residues
MLKYRRILFKISGESLAGESGYGIDAGVLVKFAEEIKEASDLGAEIALVIGGGNIFRGLSKAAASMDRVQADYMGMLATV
INSLALQDALERQGIYTRLLTAIKMEQIAEPFIRRRAVRHLEKGRVVIFGAGTGNPYFTTDTAASLRAIEIEADVIIKGT
RVEGVYDSDPEKNPDAEFFPRISYFDVIRKNLRVMDMTAITLCRENTLPIVVMNMNTKGNFTRLLKGEPIGTLVHIGEE

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=231, Percent_Identity=51.0822510822511, Blast_Score=248, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26335; Mature: 26335

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKYRRILFKISGESLAGESGYGIDAGVLVKFAEEIKEASDLGAEIALVIGGGNIFRGLS
CCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHH
KAAASMDRVQADYMGMLATVINSLALQDALERQGIYTRLLTAIKMEQIAEPFIRRRAVRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKGRVVIFGAGTGNPYFTTDTAASLRAIEIEADVIIKGTRVEGVYDSDPEKNPDAEFFP
HHCCCEEEEECCCCCCEEEECCCCCEEEEEEEEEEEEECCEECCCCCCCCCCCCCHHHCC
RISYFDVIRKNLRVMDMTAITLCRENTLPIVVMNMNTKGNFTRLLKGEPIGTLVHIGEE
CHHHHHHHHHCCEEEHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCEEEEEECCC
>Mature Secondary Structure
MLKYRRILFKISGESLAGESGYGIDAGVLVKFAEEIKEASDLGAEIALVIGGGNIFRGLS
CCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHH
KAAASMDRVQADYMGMLATVINSLALQDALERQGIYTRLLTAIKMEQIAEPFIRRRAVRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKGRVVIFGAGTGNPYFTTDTAASLRAIEIEADVIIKGTRVEGVYDSDPEKNPDAEFFP
HHCCCEEEEECCCCCCEEEECCCCCEEEEEEEEEEEEECCEECCCCCCCCCCCCCHHHCC
RISYFDVIRKNLRVMDMTAITLCRENTLPIVVMNMNTKGNFTRLLKGEPIGTLVHIGEE
CHHHHHHHHHCCEEEHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]