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The map label for this gene is tsf

Identifier: 193212095

GI number: 193212095

Start: 460604

End: 461470

Strand: Direct

Name: tsf

Synonym: Cpar_0426

Alternate gene names: 193212095

Gene position: 460604-461470 (Clockwise)

Preceding gene: 193212094

Following gene: 193212096

Centisome position: 20.12

GC content: 55.13

Gene sequence:

>867_bases
ATGAGCCAGATTTCTGCCAAGGACGTCAAGGAACTCAGGGACACCACCGGCGTCGGCATGATGGAGTGCAAGAAAGCCCT
CGAAGAGACCGGGGGAGATATGCAGAAAGCCGTCGAATACCTTCGCAAGAAAGGCGCAGCTATGGCTGCAAAGCGTGCTG
ATCGCGAAGCTTCCGAAGGCGCCGTCTGCATTCTGATGAGCGACGACCAGAAAACCGGCGTCATTCTCGAACTCAACTGC
GAAACCGACTTCGTGGCTCGCGGTGAAGTGTTTACCGGTTTTGCCAATGAGCTTGCCGAACTGGCACTCGCCAACAACTG
TGAGTCCAGAGAGGATCTGCTTGCCATCAATCTCGGTGAAGCCTACGGCAACGAGAAGGTCGAAGACGCCCTCAAGTCGA
TGACCGGTAAGGTCGGCGAGAAGCTCGAACTCAAGCGTCTTGCGATGCTCAAGGCCGAAGATGGCGTGCTTGAAAGCTAT
ATTCACCCCGGCTCGCAGCTCGGTGCTCTGATCGCTGTCGAAACCGACAAGCCGGAAGAGACCAAGGCGCTCGCCAAAGA
CCTCGCCATGCAGGTTGCTGCCGCTTCCCCGATCGAAGTCGGTCGTGATGCTGTGCCGGCAGAACTCGTTGAGAAGGAGA
AAGAGATTTACCGTCAGCAGGCTCTTGCCGAAGGCAAGAAAGAGGAGTTCGTTGATAAAATCGTCATGGGCCGTATCAAC
AAGTACTACCAGGAGGTGGTGCTGACCGAGCAGACCTTCATCAAGGATCAGAACGCCCGCGTTTCCGGCGTGCTTGACGA
CTTTATGAAGAAGAACCAGGCGCAAGTCAAAATCAAAGCCTTTGTCAGGTATCAGTTAGGAGCCTGA

Upstream 100 bases:

>100_bases
AAGCTTCCAACGACTGATCTTAACGCTTGACGCGGCCGGAACCCCCGCTGTTCCGGTCGCGCCTTTCGCAACATTCACGA
TATAATTTCTACAGACTACT

Downstream 100 bases:

>100_bases
AGCTGAAAAAAGCCTCGTTGATACGAGGCTTTTTTTTTTGCTTATTACTTATTAAGAGCAGTTAAGTTTGTCGCTTAGCC
AACCAGTAGAAGGAGATGCA

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSQISAKDVKELRDTTGVGMMECKKALEETGGDMQKAVEYLRKKGAAMAAKRADREASEGAVCILMSDDQKTGVILELNC
ETDFVARGEVFTGFANELAELALANNCESREDLLAINLGEAYGNEKVEDALKSMTGKVGEKLELKRLAMLKAEDGVLESY
IHPGSQLGALIAVETDKPEETKALAKDLAMQVAAASPIEVGRDAVPAELVEKEKEIYRQQALAEGKKEEFVDKIVMGRIN
KYYQEVVLTEQTFIKDQNARVSGVLDDFMKKNQAQVKIKAFVRYQLGA

Sequences:

>Translated_288_residues
MSQISAKDVKELRDTTGVGMMECKKALEETGGDMQKAVEYLRKKGAAMAAKRADREASEGAVCILMSDDQKTGVILELNC
ETDFVARGEVFTGFANELAELALANNCESREDLLAINLGEAYGNEKVEDALKSMTGKVGEKLELKRLAMLKAEDGVLESY
IHPGSQLGALIAVETDKPEETKALAKDLAMQVAAASPIEVGRDAVPAELVEKEKEIYRQQALAEGKKEEFVDKIVMGRIN
KYYQEVVLTEQTFIKDQNARVSGVLDDFMKKNQAQVKIKAFVRYQLGA
>Mature_287_residues
SQISAKDVKELRDTTGVGMMECKKALEETGGDMQKAVEYLRKKGAAMAAKRADREASEGAVCILMSDDQKTGVILELNCE
TDFVARGEVFTGFANELAELALANNCESREDLLAINLGEAYGNEKVEDALKSMTGKVGEKLELKRLAMLKAEDGVLESYI
HPGSQLGALIAVETDKPEETKALAKDLAMQVAAASPIEVGRDAVPAELVEKEKEIYRQQALAEGKKEEFVDKIVMGRINK
YYQEVVLTEQTFIKDQNARVSGVLDDFMKKNQAQVKIKAFVRYQLGA

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=221, Percent_Identity=31.2217194570136, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI291084500, Length=242, Percent_Identity=29.3388429752066, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI291084498, Length=106, Percent_Identity=37.7358490566038, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI291084502, Length=106, Percent_Identity=37.7358490566038, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1786366, Length=287, Percent_Identity=38.3275261324042, Blast_Score=165, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17561440, Length=310, Percent_Identity=28.7096774193548, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19921466, Length=246, Percent_Identity=28.4552845528455, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_CHLP8 (B3QLF8)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001998048.1
- GeneID:   6419340
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_0426
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- ProtClustDB:   PRK09377
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 31636; Mature: 31504

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQISAKDVKELRDTTGVGMMECKKALEETGGDMQKAVEYLRKKGAAMAAKRADREASEG
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCC
AVCILMSDDQKTGVILELNCETDFVARGEVFTGFANELAELALANNCESREDLLAINLGE
EEEEEEECCCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCH
AYGNEKVEDALKSMTGKVGEKLELKRLAMLKAEDGVLESYIHPGSQLGALIAVETDKPEE
HHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEECCCCHH
TKALAKDLAMQVAAASPIEVGRDAVPAELVEKEKEIYRQQALAEGKKEEFVDKIVMGRIN
HHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KYYQEVVLTEQTFIKDQNARVSGVLDDFMKKNQAQVKIKAFVRYQLGA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHEEHHHHEEHHCCC
>Mature Secondary Structure 
SQISAKDVKELRDTTGVGMMECKKALEETGGDMQKAVEYLRKKGAAMAAKRADREASEG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCC
AVCILMSDDQKTGVILELNCETDFVARGEVFTGFANELAELALANNCESREDLLAINLGE
EEEEEEECCCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCH
AYGNEKVEDALKSMTGKVGEKLELKRLAMLKAEDGVLESYIHPGSQLGALIAVETDKPEE
HHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEECCCCHH
TKALAKDLAMQVAAASPIEVGRDAVPAELVEKEKEIYRQQALAEGKKEEFVDKIVMGRIN
HHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KYYQEVVLTEQTFIKDQNARVSGVLDDFMKKNQAQVKIKAFVRYQLGA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHEEHHHHEEHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA