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The map label for this gene is 193212083

Identifier: 193212083

GI number: 193212083

Start: 447677

End: 448699

Strand: Direct

Name: 193212083

Synonym: Cpar_0413

Alternate gene names: NA

Gene position: 447677-448699 (Clockwise)

Preceding gene: 193212082

Following gene: 193212085

Centisome position: 19.56

GC content: 57.77

Gene sequence:

>1023_bases
ATGGACAGCGAGAAACTTCGTGCAGTAGCATCAGCTATTGTGTCGAACGGAAAAGGTGTTCTGGCGGCTGATGAGAGTAC
CCCGACCATCAAAAAGCGGCTTGATTCGATCAATGTCGAGTCCACTGAGCCCACCCGGCGTCGGTATCGTGAACTTCTTT
TTACCACCGATGGCATCGAGAGCTACATTGGTGGTGTAATCCTTTTCGATGAAACGATTCGCCAATCCACAATTGACGGT
GTTCCTTTCGCGAGAGTGCTTTCCGAACGGGGGATTGTGCCCGGAATCAAGGTTGACAAAGGGGCAAAAGCGCTGGCACA
GTATCCCGGCGAAAAGGTCACCGAGGGGCTGGATGGCCTGCGTGACCGGCTGATCGAGTATCGGGAACTTGGCGCAGGAT
TTGCGAAGTGGCGGGCAGTGATCCAGATCGATGAACACGATATTCCGTCGCCGTCCGGCATCCGTGCGAATGCCCATGCG
CTGGCTCGTTACGCCGCGCTTTGCCAGGAGCAGGACCTTGTGCCGATCGTCGAGCCCGAGGTGCTCATGGACGGCGCCCA
CGGCATCGAGCGGTGCGAGGAGGTGACTTCAAGGGTGCTTGAGGCTGTGTTTTCCGAACTTGACGCGCATCGCGTACTGT
TCGAGGGGATGTTGCTGAAGCCGAATATGGTGATCGCCGGCAAAAAATGCGCTCGCCAGAATAGCCCGGAAGAGGTTGCC
GAAGCTACGATCCGCTGCTTGAACCGTTACGTTCCGGCTGCCGTGCCGGGCATCGTGTTTCTTTCCGGCGGTCAGAGCGC
CGAGGAGGCCACCGCCAACCTGAATGCCATGAACGCGATGGGTTCGCATCCGTGGGAGGTCAGCTTCTCGTACGGACGCG
CATTGCAGACCCCCGTGCTTGCTGCCTGGCAAGGACAGGAGAGAAATGTGGCCGCTGCACAGCAAGCGCTCTTCAAACGT
AGCCGCCTGAACGGTCTTGCCCGATATGGCAAATACTCACAGGAGATGGAAGCTGAAGCGTGA

Upstream 100 bases:

>100_bases
ATAACGGAGCTTTTCGGGAATCAAGGCGTATCGTTCATTGTTGGTGAAACGAATGGGGGAATTTCAGGATGTAAGGAATG
CAAAACGAGAGGAGGAGTGT

Downstream 100 bases:

>100_bases
ACTTGTTTTTTTATGTTCAACTTTCCCCTGTCGGTTCAGCAATGATCTGATTTTACCAGCCCGCCTCCAGCCCGAACGAG
CTGGTCGTGCCGAGGTCAAG

Product: Fructose-bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MDSEKLRAVASAIVSNGKGVLAADESTPTIKKRLDSINVESTEPTRRRYRELLFTTDGIESYIGGVILFDETIRQSTIDG
VPFARVLSERGIVPGIKVDKGAKALAQYPGEKVTEGLDGLRDRLIEYRELGAGFAKWRAVIQIDEHDIPSPSGIRANAHA
LARYAALCQEQDLVPIVEPEVLMDGAHGIERCEEVTSRVLEAVFSELDAHRVLFEGMLLKPNMVIAGKKCARQNSPEEVA
EATIRCLNRYVPAAVPGIVFLSGGQSAEEATANLNAMNAMGSHPWEVSFSYGRALQTPVLAAWQGQERNVAAAQQALFKR
SRLNGLARYGKYSQEMEAEA

Sequences:

>Translated_340_residues
MDSEKLRAVASAIVSNGKGVLAADESTPTIKKRLDSINVESTEPTRRRYRELLFTTDGIESYIGGVILFDETIRQSTIDG
VPFARVLSERGIVPGIKVDKGAKALAQYPGEKVTEGLDGLRDRLIEYRELGAGFAKWRAVIQIDEHDIPSPSGIRANAHA
LARYAALCQEQDLVPIVEPEVLMDGAHGIERCEEVTSRVLEAVFSELDAHRVLFEGMLLKPNMVIAGKKCARQNSPEEVA
EATIRCLNRYVPAAVPGIVFLSGGQSAEEATANLNAMNAMGSHPWEVSFSYGRALQTPVLAAWQGQERNVAAAQQALFKR
SRLNGLARYGKYSQEMEAEA
>Mature_340_residues
MDSEKLRAVASAIVSNGKGVLAADESTPTIKKRLDSINVESTEPTRRRYRELLFTTDGIESYIGGVILFDETIRQSTIDG
VPFARVLSERGIVPGIKVDKGAKALAQYPGEKVTEGLDGLRDRLIEYRELGAGFAKWRAVIQIDEHDIPSPSGIRANAHA
LARYAALCQEQDLVPIVEPEVLMDGAHGIERCEEVTSRVLEAVFSELDAHRVLFEGMLLKPNMVIAGKKCARQNSPEEVA
EATIRCLNRYVPAAVPGIVFLSGGQSAEEATANLNAMNAMGSHPWEVSFSYGRALQTPVLAAWQGQERNVAAAQQALFKR
SRLNGLARYGKYSQEMEAEA

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI4885063, Length=331, Percent_Identity=52.8700906344411, Blast_Score=343, Evalue=1e-94,
Organism=Homo sapiens, GI34577112, Length=339, Percent_Identity=52.8023598820059, Blast_Score=340, Evalue=8e-94,
Organism=Homo sapiens, GI34577110, Length=339, Percent_Identity=52.8023598820059, Blast_Score=340, Evalue=8e-94,
Organism=Homo sapiens, GI4557305, Length=339, Percent_Identity=52.8023598820059, Blast_Score=340, Evalue=8e-94,
Organism=Homo sapiens, GI193794814, Length=339, Percent_Identity=52.8023598820059, Blast_Score=340, Evalue=8e-94,
Organism=Homo sapiens, GI40354205, Length=331, Percent_Identity=52.5679758308157, Blast_Score=340, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI71983985, Length=330, Percent_Identity=53.6363636363636, Blast_Score=348, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI25150450, Length=333, Percent_Identity=51.6516516516517, Blast_Score=343, Evalue=9e-95,
Organism=Caenorhabditis elegans, GI71983990, Length=236, Percent_Identity=51.271186440678, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI24650282, Length=331, Percent_Identity=54.0785498489426, Blast_Score=343, Evalue=1e-94,
Organism=Drosophila melanogaster, GI24650280, Length=331, Percent_Identity=54.0785498489426, Blast_Score=343, Evalue=1e-94,
Organism=Drosophila melanogaster, GI24650278, Length=331, Percent_Identity=54.0785498489426, Blast_Score=343, Evalue=1e-94,
Organism=Drosophila melanogaster, GI221459619, Length=332, Percent_Identity=53.6144578313253, Blast_Score=342, Evalue=3e-94,
Organism=Drosophila melanogaster, GI24650288, Length=332, Percent_Identity=53.6144578313253, Blast_Score=342, Evalue=3e-94,
Organism=Drosophila melanogaster, GI45553577, Length=331, Percent_Identity=53.4743202416918, Blast_Score=338, Evalue=4e-93,
Organism=Drosophila melanogaster, GI24650304, Length=331, Percent_Identity=45.9214501510574, Blast_Score=305, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 37154; Mature: 37154

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00158 ALDOLASE_CLASS_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSEKLRAVASAIVSNGKGVLAADESTPTIKKRLDSINVESTEPTRRRYRELLFTTDGIE
CCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHH
SYIGGVILFDETIRQSTIDGVPFARVLSERGIVPGIKVDKGAKALAQYPGEKVTEGLDGL
HHHCCEEEEHHHHHHHHCCCCHHHHHHHHCCCCCCCEECCCHHHHHHCCCHHHHHHHHHH
RDRLIEYRELGAGFAKWRAVIQIDEHDIPSPSGIRANAHALARYAALCQEQDLVPIVEPE
HHHHHHHHHHCCCHHHHEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHH
VLMDGAHGIERCEEVTSRVLEAVFSELDAHRVLFEGMLLKPNMVIAGKKCARQNSPEEVA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCEEEECHHHHCCCCHHHHH
EATIRCLNRYVPAAVPGIVFLSGGQSAEEATANLNAMNAMGSHPWEVSFSYGRALQTPVL
HHHHHHHHHHCCHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEHHCCHHCCCHH
AAWQGQERNVAAAQQALFKRSRLNGLARYGKYSQEMEAEA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCC
>Mature Secondary Structure
MDSEKLRAVASAIVSNGKGVLAADESTPTIKKRLDSINVESTEPTRRRYRELLFTTDGIE
CCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHH
SYIGGVILFDETIRQSTIDGVPFARVLSERGIVPGIKVDKGAKALAQYPGEKVTEGLDGL
HHHCCEEEEHHHHHHHHCCCCHHHHHHHHCCCCCCCEECCCHHHHHHCCCHHHHHHHHHH
RDRLIEYRELGAGFAKWRAVIQIDEHDIPSPSGIRANAHALARYAALCQEQDLVPIVEPE
HHHHHHHHHHCCCHHHHEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHH
VLMDGAHGIERCEEVTSRVLEAVFSELDAHRVLFEGMLLKPNMVIAGKKCARQNSPEEVA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCEEEECHHHHCCCCHHHHH
EATIRCLNRYVPAAVPGIVFLSGGQSAEEATANLNAMNAMGSHPWEVSFSYGRALQTPVL
HHHHHHHHHHCCHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEHHCCHHCCCHH
AAWQGQERNVAAAQQALFKRSRLNGLARYGKYSQEMEAEA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]