Click here to switch to the map view.

The map label for this gene is dtd

Identifier: 193212042

GI number: 193212042

Start: 397763

End: 398212

Strand: Direct

Name: dtd

Synonym: Cpar_0371

Alternate gene names: 193212042

Gene position: 397763-398212 (Clockwise)

Preceding gene: 193212041

Following gene: 193212043

Centisome position: 17.38

GC content: 61.56

Gene sequence:

>450_bases
ATGAGGTGTGTTGTGCAGCGGGTGCGCGAGGCGAGCGTTACCATCGGCGGTGAACGTTTCAGCTCTATCGGCGCGGGGCT
GCTCGTGCTGGCCGGAATCTCGCGCGAGGATACGGAAGCCGATCTCGCCTGGATGAGCCGCAAGCTCCCCAACCTGCGCA
TTTTCGAGGACGATGAAGGCAGAATGAACCGCTCGGTCAAAGAGATCGGCGGCGAACTCCTCGTCGTCTCGCAATTTACG
CTCTACGCTGACGCTAGCCGCGGCAACCGTCCCGGCTTCACCGAATCCGCGCCCTCCGAAGTCGCCCAGCCGCTTTTCGA
CCGCTTCGTCGAACTGCTCCGCCGCGAGTCCGGTCTGCCGGTTGAAACCGGAAGCTTCGGTGCGGACATGCAGGTCTCGC
TCATCAACGACGGGCCGGTCACCATTATTCTCGAATCACCGAAAAAGTAA

Upstream 100 bases:

>100_bases
AGACCTCGCGCAGCAAGGTGCTGAAGGTGGAGGGCATGACGCCCTCCGAGCTTCGCAAAGCGCTCGCTCCCGTGCTCGGC
GATGAATCGGAGGCGGGCGC

Downstream 100 bases:

>100_bases
GGGGCATGGCGTGCGCCTGTTGTGTGCTGTCATTTTTCGATGCTCCCAAAAACGGGCGACCGCAAGGGATCGTCCCTACA
TCATTGAAATCGAGTTCTGA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MRCVVQRVREASVTIGGERFSSIGAGLLVLAGISREDTEADLAWMSRKLPNLRIFEDDEGRMNRSVKEIGGELLVVSQFT
LYADASRGNRPGFTESAPSEVAQPLFDRFVELLRRESGLPVETGSFGADMQVSLINDGPVTIILESPKK

Sequences:

>Translated_149_residues
MRCVVQRVREASVTIGGERFSSIGAGLLVLAGISREDTEADLAWMSRKLPNLRIFEDDEGRMNRSVKEIGGELLVVSQFT
LYADASRGNRPGFTESAPSEVAQPLFDRFVELLRRESGLPVETGSFGADMQVSLINDGPVTIILESPKK
>Mature_149_residues
MRCVVQRVREASVTIGGERFSSIGAGLLVLAGISREDTEADLAWMSRKLPNLRIFEDDEGRMNRSVKEIGGELLVVSQFT
LYADASRGNRPGFTESAPSEVAQPLFDRFVELLRRESGLPVETGSFGADMQVSLINDGPVTIILESPKK

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=150, Percent_Identity=50.6666666666667, Blast_Score=137, Evalue=4e-33,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=49.6551724137931, Blast_Score=139, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI115533292, Length=152, Percent_Identity=42.1052631578947, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319982, Length=150, Percent_Identity=42.6666666666667, Blast_Score=124, Evalue=7e-30,
Organism=Drosophila melanogaster, GI281361569, Length=150, Percent_Identity=47.3333333333333, Blast_Score=132, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_CHLP8 (B3QL07)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001997995.1
- GeneID:   6419285
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_0371
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16329; Mature: 16329

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCVVQRVREASVTIGGERFSSIGAGLLVLAGISREDTEADLAWMSRKLPNLRIFEDDEG
CHHHHHHHHHHHEEECCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCC
RMNRSVKEIGGELLVVSQFTLYADASRGNRPGFTESAPSEVAQPLFDRFVELLRRESGLP
HHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
VETGSFGADMQVSLINDGPVTIILESPKK
CCCCCCCCCEEEEEECCCCEEEEEECCCC
>Mature Secondary Structure
MRCVVQRVREASVTIGGERFSSIGAGLLVLAGISREDTEADLAWMSRKLPNLRIFEDDEG
CHHHHHHHHHHHEEECCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCC
RMNRSVKEIGGELLVVSQFTLYADASRGNRPGFTESAPSEVAQPLFDRFVELLRRESGLP
HHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
VETGSFGADMQVSLINDGPVTIILESPKK
CCCCCCCCCEEEEEECCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA