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The map label for this gene is kdsB

Identifier: 193212043

GI number: 193212043

Start: 398331

End: 399077

Strand: Direct

Name: kdsB

Synonym: Cpar_0372

Alternate gene names: 193212043

Gene position: 398331-399077 (Clockwise)

Preceding gene: 193212042

Following gene: 193212045

Centisome position: 17.4

GC content: 62.12

Gene sequence:

>747_bases
ATGAACGTCGTCATCGTCATCCCCGCGCGTCTCTCATCCAACCGCCTGAAAGAAAAAATGCTGGCCGATCTGGAAGGCGC
TCCGCTGATCGTGCGCACCTGGCAGCAGGCGATGAAGTCGCGCCTTGCCAACCGTGTGGTGGTGGCGACCGACAGCGAGC
GCATTTTCGCGGTGCTGCGTGACGCCGGGGCCGAGGTGGTGATGACCTCGCCCGACCTCACCTGTGGCACCGACCGCATC
GCCGAGGCCGCCGAGCAGGTCGGTGGCGACGTCTTCGTCAATCTCCAGGGCGACGAGCCGCTCATCGACCCGGCGACCAT
CGACCTCGCCATCGCGCCTTTCTTTGAAGATGGTCCGATGCCAGACTGCACCACGCTGGTCTTCCCGCTGAAGCCGGATG
AGCGGCACATCATCGACGACCCACACGTCGTCAAGGCTGTGCTCGACGCCAAAGGCAATGCGCTCTACTTCTCCCGCTGC
CCGATACCCTATCGCCGCGAAACCCTGCCCGACACCCGCTATTATCGTCACATCGGCCTCTACGCTTTCCGTGCCGACGT
GCTCAAAGCGTTCGTCGCACTTCCCCCCTCGATGCTCGAACGCACCGAATCCCTCGAACAGCTTCGCCTGCTCGAAAACG
GCTACCGCATCCGCTGCATCGAAACGACAACGGATACGCCGGGCGTCAATACCGAGGAGGAGCTGGAAGAGGTAAGGAGG
TTGTTCAGGGAAAGGTTTGGTTCGTAA

Upstream 100 bases:

>100_bases
GTTGTGTGCTGTCATTTTTCGATGCTCCCAAAAACGGGCGACCGCAAGGGATCGTCCCTACATCATTGAAATCGAGTTCT
GATAACGCTACTATCCGCCC

Downstream 100 bases:

>100_bases
CCTTCGCCTCTCGCCGCCCGTCGTGGAATGTGATGCCGATCTTCGCCCCTTCTTCGAGCGCTTTTGCTGAGGTCACGTAA
CGATCATCCTGCGATACCAG

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNVVIVIPARLSSNRLKEKMLADLEGAPLIVRTWQQAMKSRLANRVVVATDSERIFAVLRDAGAEVVMTSPDLTCGTDRI
AEAAEQVGGDVFVNLQGDEPLIDPATIDLAIAPFFEDGPMPDCTTLVFPLKPDERHIIDDPHVVKAVLDAKGNALYFSRC
PIPYRRETLPDTRYYRHIGLYAFRADVLKAFVALPPSMLERTESLEQLRLLENGYRIRCIETTTDTPGVNTEEELEEVRR
LFRERFGS

Sequences:

>Translated_248_residues
MNVVIVIPARLSSNRLKEKMLADLEGAPLIVRTWQQAMKSRLANRVVVATDSERIFAVLRDAGAEVVMTSPDLTCGTDRI
AEAAEQVGGDVFVNLQGDEPLIDPATIDLAIAPFFEDGPMPDCTTLVFPLKPDERHIIDDPHVVKAVLDAKGNALYFSRC
PIPYRRETLPDTRYYRHIGLYAFRADVLKAFVALPPSMLERTESLEQLRLLENGYRIRCIETTTDTPGVNTEEELEEVRR
LFRERFGS
>Mature_248_residues
MNVVIVIPARLSSNRLKEKMLADLEGAPLIVRTWQQAMKSRLANRVVVATDSERIFAVLRDAGAEVVMTSPDLTCGTDRI
AEAAEQVGGDVFVNLQGDEPLIDPATIDLAIAPFFEDGPMPDCTTLVFPLKPDERHIIDDPHVVKAVLDAKGNALYFSRC
PIPYRRETLPDTRYYRHIGLYAFRADVLKAFVALPPSMLERTESLEQLRLLENGYRIRCIETTTDTPGVNTEEELEEVRR
LFRERFGS

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=255, Percent_Identity=41.5686274509804, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_CHLP8 (B3QL08)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001997996.1
- GeneID:   6419286
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_0372
- HOGENOM:   HBG637773
- OMA:   FSRAPLP
- ProtClustDB:   PRK05450
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 27887; Mature: 27887

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVVIVIPARLSSNRLKEKMLADLEGAPLIVRTWQQAMKSRLANRVVVATDSERIFAVLR
CCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEEEECCHHHHHHHH
DAGAEVVMTSPDLTCGTDRIAEAAEQVGGDVFVNLQGDEPLIDPATIDLAIAPFFEDGPM
HCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCC
PDCTTLVFPLKPDERHIIDDPHVVKAVLDAKGNALYFSRCPIPYRRETLPDTRYYRHIGL
CCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHH
YAFRADVLKAFVALPPSMLERTESLEQLRLLENGYRIRCIETTTDTPGVNTEEELEEVRR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHH
LFRERFGS
HHHHHHCC
>Mature Secondary Structure
MNVVIVIPARLSSNRLKEKMLADLEGAPLIVRTWQQAMKSRLANRVVVATDSERIFAVLR
CCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEEEECCHHHHHHHH
DAGAEVVMTSPDLTCGTDRIAEAAEQVGGDVFVNLQGDEPLIDPATIDLAIAPFFEDGPM
HCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCC
PDCTTLVFPLKPDERHIIDDPHVVKAVLDAKGNALYFSRCPIPYRRETLPDTRYYRHIGL
CCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHH
YAFRADVLKAFVALPPSMLERTESLEQLRLLENGYRIRCIETTTDTPGVNTEEELEEVRR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHH
LFRERFGS
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA