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The map label for this gene is zwf [H]

Identifier: 193212006

GI number: 193212006

Start: 355416

End: 356837

Strand: Direct

Name: zwf [H]

Synonym: Cpar_0335

Alternate gene names: 193212006

Gene position: 355416-356837 (Clockwise)

Preceding gene: 193212005

Following gene: 193212010

Centisome position: 15.53

GC content: 60.55

Gene sequence:

>1422_bases
ATGAACGGCAAACCGGGCAACTTGACGATCGTCATCTTCGGCGCGGACGGCGATCTTGCGTCGCGCAAGCTCTTTCCCTC
GATCTTCCAGCTCGACCGCTGGGGCCACATGCCGGAGCATTTCCGGGTGATCGGCGTCGGGCGGCGCGACCTGACCCACG
GAGTGTTCCGCGATTTCGTGCGCGACCGCCTGCTCGAACACTCGCCCGAAGCTGCCGGGGACGATGAGCAGCTGAAAGCG
TTCTGCGACCTTTTTTTCTACGTGAACGTCGATCTGCGCAAACCGGAAGCGTATCAGGAGTTGCGCGAAAAAATCATGGA
GGACGAGACCTCGAGCAACCTGCTCTTTTACCTCTCGATTCCCCCGAGCCTCGCCCCGCCGGTGGTGCGCAACCTTGCGG
AAGCCGGACTCGGCGGACGCGAGCCGAACGTGCCCGGCTGGCGCAAGCTCGTTGCCGAAAAGCCCTACGGCCACGACCTC
GAAAGCGCCCACGAACTGAACCGAGTCATCGACGAGGCGTTCGACGAAAGCCAGGTCTATCGCATCGACCACTACCTCGG
CAAGGAGCCGGTGCAGAACATCATGGTGTTCCGTTTCTCCAACGGTATCTTCGAGCCGCTCTGGAACCGGCAGTACATCG
CGCAGGTGCAGATCACCATCGCCGAGGATTTCGGCATCCGGGATCGCGGCGGCTACTACGAGGAGGCGGGATTGCTGCGC
GACATCATCCAGAACCACGGCTTGCAGCTTCTGGCGGCTATCGCGATGGAGCCGCCGGTCGATCTCAGCGCTGATGGCAT
CCGCGACGAAAAGTCCAAAATCCTGCGTTCGATTCGCCATTTTTCTCCCGATACGATTAGCGATACGGCGGTGGTGGGTC
AGTACGAAGGGTATCACAGCGAAAAGGGCGTTGCGCCCGATTCACGGGTCGAGACCTTTGCCGCTGTCAAATTCCACATC
GACAACTGGCGCTGGTCGGGCGTGCCGTTCTACATGAAGGCCGGGAAGAATCTCGCCAAGCACGTGACCGAAATCATCAT
TACCTTCAAATGCCCGCCGCAGAACTACTACGGTGCCTCCGCAGCAGCGTGCAGCACGCCGAACCAGGTGGTGCTCGGCA
TCCAGCCCGACGAAACCGTCGCCATTCGCTTCGGCACCAAGCGCCCCGGCGAGCAGATGGTCACCGACCCGGTTTTCATG
AAATTCGATTACCGCGAAACCTTCCCCGGCGAGCAGTTGACCCCGTATCACCGATTGTTGCTCGACGCTATCGAAGGCAA
CCAGATGAACTTCATCCGCAAAGACAGCGTCGAAACCTCCTGGCAAATCATCGACAGCCTGCGCGACTCGCTCGACGGCA
TCACGCCCGAGCGCTATCCACCCCACTCCTGGGGGCCTGATGCGTCGCATTTGTATGGGTGA

Upstream 100 bases:

>100_bases
CGCAGAGCGAGGAGAATTTTTCGGACAAGGTGGTCGCCGCGTTGCGCCACGAGTTCGGCGGGCACGCCTATGAGAAACCC
GGCGATGGGGAGGGGAAGGC

Downstream 100 bases:

>100_bases
GATGAATTTTGAGGAGGGTTGAAAATTCTGTCATGGACACTCAATCTTACATTGCCATGTTCAATTGTCCCGGTTTCTTT
CACTCAGGAGGGTTTCAACC

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MNGKPGNLTIVIFGADGDLASRKLFPSIFQLDRWGHMPEHFRVIGVGRRDLTHGVFRDFVRDRLLEHSPEAAGDDEQLKA
FCDLFFYVNVDLRKPEAYQELREKIMEDETSSNLLFYLSIPPSLAPPVVRNLAEAGLGGREPNVPGWRKLVAEKPYGHDL
ESAHELNRVIDEAFDESQVYRIDHYLGKEPVQNIMVFRFSNGIFEPLWNRQYIAQVQITIAEDFGIRDRGGYYEEAGLLR
DIIQNHGLQLLAAIAMEPPVDLSADGIRDEKSKILRSIRHFSPDTISDTAVVGQYEGYHSEKGVAPDSRVETFAAVKFHI
DNWRWSGVPFYMKAGKNLAKHVTEIIITFKCPPQNYYGASAAACSTPNQVVLGIQPDETVAIRFGTKRPGEQMVTDPVFM
KFDYRETFPGEQLTPYHRLLLDAIEGNQMNFIRKDSVETSWQIIDSLRDSLDGITPERYPPHSWGPDASHLYG

Sequences:

>Translated_473_residues
MNGKPGNLTIVIFGADGDLASRKLFPSIFQLDRWGHMPEHFRVIGVGRRDLTHGVFRDFVRDRLLEHSPEAAGDDEQLKA
FCDLFFYVNVDLRKPEAYQELREKIMEDETSSNLLFYLSIPPSLAPPVVRNLAEAGLGGREPNVPGWRKLVAEKPYGHDL
ESAHELNRVIDEAFDESQVYRIDHYLGKEPVQNIMVFRFSNGIFEPLWNRQYIAQVQITIAEDFGIRDRGGYYEEAGLLR
DIIQNHGLQLLAAIAMEPPVDLSADGIRDEKSKILRSIRHFSPDTISDTAVVGQYEGYHSEKGVAPDSRVETFAAVKFHI
DNWRWSGVPFYMKAGKNLAKHVTEIIITFKCPPQNYYGASAAACSTPNQVVLGIQPDETVAIRFGTKRPGEQMVTDPVFM
KFDYRETFPGEQLTPYHRLLLDAIEGNQMNFIRKDSVETSWQIIDSLRDSLDGITPERYPPHSWGPDASHLYG
>Mature_473_residues
MNGKPGNLTIVIFGADGDLASRKLFPSIFQLDRWGHMPEHFRVIGVGRRDLTHGVFRDFVRDRLLEHSPEAAGDDEQLKA
FCDLFFYVNVDLRKPEAYQELREKIMEDETSSNLLFYLSIPPSLAPPVVRNLAEAGLGGREPNVPGWRKLVAEKPYGHDL
ESAHELNRVIDEAFDESQVYRIDHYLGKEPVQNIMVFRFSNGIFEPLWNRQYIAQVQITIAEDFGIRDRGGYYEEAGLLR
DIIQNHGLQLLAAIAMEPPVDLSADGIRDEKSKILRSIRHFSPDTISDTAVVGQYEGYHSEKGVAPDSRVETFAAVKFHI
DNWRWSGVPFYMKAGKNLAKHVTEIIITFKCPPQNYYGASAAACSTPNQVVLGIQPDETVAIRFGTKRPGEQMVTDPVFM
KFDYRETFPGEQLTPYHRLLLDAIEGNQMNFIRKDSVETSWQIIDSLRDSLDGITPERYPPHSWGPDASHLYG

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI109389365, Length=464, Percent_Identity=35.3448275862069, Blast_Score=284, Evalue=1e-76,
Organism=Homo sapiens, GI108773793, Length=464, Percent_Identity=35.3448275862069, Blast_Score=284, Evalue=1e-76,
Organism=Homo sapiens, GI52145310, Length=495, Percent_Identity=30.1010101010101, Blast_Score=189, Evalue=6e-48,
Organism=Escherichia coli, GI1788158, Length=477, Percent_Identity=39.832285115304, Blast_Score=340, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17538218, Length=479, Percent_Identity=36.3256784968685, Blast_Score=298, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6324088, Length=486, Percent_Identity=35.8024691358025, Blast_Score=294, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24643350, Length=475, Percent_Identity=34.7368421052632, Blast_Score=279, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24643352, Length=475, Percent_Identity=34.7368421052632, Blast_Score=278, Evalue=6e-75,
Organism=Drosophila melanogaster, GI221513548, Length=467, Percent_Identity=29.7644539614561, Blast_Score=206, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 53685; Mature: 53685

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00069 G6P_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGKPGNLTIVIFGADGDLASRKLFPSIFQLDRWGHMPEHFRVIGVGRRDLTHGVFRDFV
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHH
RDRLLEHSPEAAGDDEQLKAFCDLFFYVNVDLRKPEAYQELREKIMEDETSSNLLFYLSI
HHHHHHCCCCCCCCHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEC
PPSLAPPVVRNLAEAGLGGREPNVPGWRKLVAEKPYGHDLESAHELNRVIDEAFDESQVY
CCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEE
RIDHYLGKEPVQNIMVFRFSNGIFEPLWNRQYIAQVQITIAEDFGIRDRGGYYEEAGLLR
EHHHHHCCCHHHHEEEEEECCCCCCHHCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHH
DIIQNHGLQLLAAIAMEPPVDLSADGIRDEKSKILRSIRHFSPDTISDTAVVGQYEGYHS
HHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCC
EKGVAPDSRVETFAAVKFHIDNWRWSGVPFYMKAGKNLAKHVTEIIITFKCPPQNYYGAS
CCCCCCCHHHHEEEEEEEEECCEEECCCCHHHHCCCHHHHHHHHEEEEEECCCCCCCCCC
AAACSTPNQVVLGIQPDETVAIRFGTKRPGEQMVTDPVFMKFDYRETFPGEQLTPYHRLL
CCCCCCCCEEEEEECCCCEEEEEECCCCCCCHHCCCCEEEEECCHHCCCCCCCCHHHHHH
LDAIEGNQMNFIRKDSVETSWQIIDSLRDSLDGITPERYPPHSWGPDASHLYG
HHHHCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure
MNGKPGNLTIVIFGADGDLASRKLFPSIFQLDRWGHMPEHFRVIGVGRRDLTHGVFRDFV
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHH
RDRLLEHSPEAAGDDEQLKAFCDLFFYVNVDLRKPEAYQELREKIMEDETSSNLLFYLSI
HHHHHHCCCCCCCCHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEC
PPSLAPPVVRNLAEAGLGGREPNVPGWRKLVAEKPYGHDLESAHELNRVIDEAFDESQVY
CCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEE
RIDHYLGKEPVQNIMVFRFSNGIFEPLWNRQYIAQVQITIAEDFGIRDRGGYYEEAGLLR
EHHHHHCCCHHHHEEEEEECCCCCCHHCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHH
DIIQNHGLQLLAAIAMEPPVDLSADGIRDEKSKILRSIRHFSPDTISDTAVVGQYEGYHS
HHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCC
EKGVAPDSRVETFAAVKFHIDNWRWSGVPFYMKAGKNLAKHVTEIIITFKCPPQNYYGAS
CCCCCCCHHHHEEEEEEEEECCEEECCCCHHHHCCCHHHHHHHHEEEEEECCCCCCCCCC
AAACSTPNQVVLGIQPDETVAIRFGTKRPGEQMVTDPVFMKFDYRETFPGEQLTPYHRLL
CCCCCCCCEEEEEECCCCEEEEEECCCCCCCHHCCCCEEEEECCHHCCCCCCCCHHHHHH
LDAIEGNQMNFIRKDSVETSWQIIDSLRDSLDGITPERYPPHSWGPDASHLYG
HHHHCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]