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The map label for this gene is obgE

Identifier: 193211829

GI number: 193211829

Start: 168007

End: 169014

Strand: Direct

Name: obgE

Synonym: Cpar_0155

Alternate gene names: 193211829

Gene position: 168007-169014 (Clockwise)

Preceding gene: 193211827

Following gene: 193211830

Centisome position: 7.34

GC content: 59.13

Gene sequence:

>1008_bases
GTGAAGTTTGTCGATAGTGCGAAAATCTCGGTCAAGGCTGGTGACGGCGGACGGGGATGCGTGAGTTTCAGAAGAGAAAA
GTTCGTGCCCAAGGGAGGCCCCGATGGCGGTGATGGCGGGCGCGGCGGCCATGTTTATCTGCGTGCCAACCGGCAGCTCT
CCACTCTGCTCGACTTCAAGTACCGCAAGTCCTACATCGCCGGTCGTGGCGAACACGGCATGGGCGCGCGCAAGAGTGGC
AAGAACGGCAATGACGTCGTGATCGGCGTTCCCTGCGGTACGGTGGTGCGCAATGCCGAAACCGGTGAAGTGCTCTGCGA
TATGGTCGAAGACGGCCAGGAGATCATGATCGCCAAGGGCGGACGTGGCGGCCAGGGCAACCAGCATTTTGCCACGGCCA
CCCGTCAGGCACCGCGATTCGCACAGCCCGGTGAAAAGGGCGATGAGATCGAGCTTGAGATGGAACTGAAGCTGATGGCC
GACGTTGGCCTCGTGGGCTTCCCGAACGCGGGTAAATCGACCCTGATCTCGGTGTTCAGCGCCGCACGTCCGAAGATCGC
CGATTATCCTTTCACCACGCTGGTGCCCAATCTCGGCATCGTACGTTACGATGACTACAAGTCGTTCGTGATGGCCGACA
TTCCCGGCATTATCGAGGGGGCTGCCGAAGGGCGCGGTCTTGGAATTCAGTTTCTGCGCCATATCCAGCGCACCAAAACC
CTGCTCGTCATGGTGCCGTCCGATTCGGCCGATATTGCCGCCGAGTACGCAACCCTGCTTCGTGAGCTCGAGAAGTTCGA
TGCCTCGCTGCTCTCCAAACCGAGGCTTGCGGTGATCACCAAGATGGACATCGCGCCGGAAGATTTTGCCATACCGGAGC
TTGAGCCGGGCATCAAGGTTATCGCTATTTCAAGCGTGGCCGGTCAGGGGCTCAAAGCGCTCAAGGATGAATTGTGGAGA
CAGATTTCCACTTCAACCCAGATCACCGTTGACGATGCCGGCAACTGA

Upstream 100 bases:

>100_bases
TTACGTGCAGCAGGCATTGTTAGTGCAGGGTTAAGTTCAGAATAACTTAGGTAACGATGGCGATTCCTACAAAAAGGATT
CTTACAAAAAGGACGGAAGC

Downstream 100 bases:

>100_bases
GACCATCATCCGCAACGCGCGGCTGAATGAGGCTGAACAGATTTCCCGGATGACGGACGCTTATGCCGGGAAGGGCATCA
TGCTCAAGCGGCCTGTCGAG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKFVDSAKISVKAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHVYLRANRQLSTLLDFKYRKSYIAGRGEHGMGARKSG
KNGNDVVIGVPCGTVVRNAETGEVLCDMVEDGQEIMIAKGGRGGQGNQHFATATRQAPRFAQPGEKGDEIELEMELKLMA
DVGLVGFPNAGKSTLISVFSAARPKIADYPFTTLVPNLGIVRYDDYKSFVMADIPGIIEGAAEGRGLGIQFLRHIQRTKT
LLVMVPSDSADIAAEYATLLRELEKFDASLLSKPRLAVITKMDIAPEDFAIPELEPGIKVIAISSVAGQGLKALKDELWR
QISTSTQITVDDAGN

Sequences:

>Translated_335_residues
MKFVDSAKISVKAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHVYLRANRQLSTLLDFKYRKSYIAGRGEHGMGARKSG
KNGNDVVIGVPCGTVVRNAETGEVLCDMVEDGQEIMIAKGGRGGQGNQHFATATRQAPRFAQPGEKGDEIELEMELKLMA
DVGLVGFPNAGKSTLISVFSAARPKIADYPFTTLVPNLGIVRYDDYKSFVMADIPGIIEGAAEGRGLGIQFLRHIQRTKT
LLVMVPSDSADIAAEYATLLRELEKFDASLLSKPRLAVITKMDIAPEDFAIPELEPGIKVIAISSVAGQGLKALKDELWR
QISTSTQITVDDAGN
>Mature_335_residues
MKFVDSAKISVKAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHVYLRANRQLSTLLDFKYRKSYIAGRGEHGMGARKSG
KNGNDVVIGVPCGTVVRNAETGEVLCDMVEDGQEIMIAKGGRGGQGNQHFATATRQAPRFAQPGEKGDEIELEMELKLMA
DVGLVGFPNAGKSTLISVFSAARPKIADYPFTTLVPNLGIVRYDDYKSFVMADIPGIIEGAAEGRGLGIQFLRHIQRTKT
LLVMVPSDSADIAAEYATLLRELEKFDASLLSKPRLAVITKMDIAPEDFAIPELEPGIKVIAISSVAGQGLKALKDELWR
QISTSTQITVDDAGN

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=314, Percent_Identity=41.4012738853503, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI111955139, Length=346, Percent_Identity=36.1271676300578, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI111955063, Length=182, Percent_Identity=39.5604395604396, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI4758796, Length=115, Percent_Identity=40.8695652173913, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI4557537, Length=105, Percent_Identity=38.0952380952381, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1789574, Length=328, Percent_Identity=50.9146341463415, Blast_Score=277, Evalue=6e-76,
Organism=Escherichia coli, GI1787454, Length=96, Percent_Identity=37.5, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=327, Percent_Identity=38.5321100917431, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17552324, Length=339, Percent_Identity=30.0884955752212, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI71981008, Length=115, Percent_Identity=37.3913043478261, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17555344, Length=115, Percent_Identity=40, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=162, Percent_Identity=40.1234567901235, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6319281, Length=87, Percent_Identity=47.1264367816092, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321612, Length=105, Percent_Identity=38.0952380952381, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129375, Length=321, Percent_Identity=39.5638629283489, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24585318, Length=292, Percent_Identity=35.6164383561644, Blast_Score=147, Evalue=7e-36,
Organism=Drosophila melanogaster, GI21356473, Length=125, Percent_Identity=37.6, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_CHLP8 (B3QRD8)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001997782.1
- GeneID:   6419062
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_0155
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- ProtClustDB:   PRK12299
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 35900; Mature: 35900

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDSAKISVKAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHVYLRANRQLSTLLDFK
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
YRKSYIAGRGEHGMGARKSGKNGNDVVIGVPCGTVVRNAETGEVLCDMVEDGQEIMIAKG
HHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCCHHHHHHHHHCCCEEEEEEC
GRGGQGNQHFATATRQAPRFAQPGEKGDEIELEMELKLMADVGLVGFPNAGKSTLISVFS
CCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHHH
AARPKIADYPFTTLVPNLGIVRYDDYKSFVMADIPGIIEGAAEGRGLGIQFLRHIQRTKT
HCCCCCCCCCHHHHCCCCCEEEECCCHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHCCE
LLVMVPSDSADIAAEYATLLRELEKFDASLLSKPRLAVITKMDIAPEDFAIPELEPGIKV
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEE
IAISSVAGQGLKALKDELWRQISTSTQITVDDAGN
EEEECHHCCCHHHHHHHHHHHHCCCCEEEEECCCC
>Mature Secondary Structure
MKFVDSAKISVKAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHVYLRANRQLSTLLDFK
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
YRKSYIAGRGEHGMGARKSGKNGNDVVIGVPCGTVVRNAETGEVLCDMVEDGQEIMIAKG
HHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCCHHHHHHHHHCCCEEEEEEC
GRGGQGNQHFATATRQAPRFAQPGEKGDEIELEMELKLMADVGLVGFPNAGKSTLISVFS
CCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHHH
AARPKIADYPFTTLVPNLGIVRYDDYKSFVMADIPGIIEGAAEGRGLGIQFLRHIQRTKT
HCCCCCCCCCHHHHCCCCCEEEECCCHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHCCE
LLVMVPSDSADIAAEYATLLRELEKFDASLLSKPRLAVITKMDIAPEDFAIPELEPGIKV
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEE
IAISSVAGQGLKALKDELWRQISTSTQITVDDAGN
EEEECHHCCCHHHHHHHHHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA