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The map label for this gene is msrB [H]

Identifier: 193211728

GI number: 193211728

Start: 60012

End: 60455

Strand: Direct

Name: msrB [H]

Synonym: Cpar_0053

Alternate gene names: 193211728

Gene position: 60012-60455 (Clockwise)

Preceding gene: 193211727

Following gene: 193211733

Centisome position: 2.62

GC content: 60.14

Gene sequence:

>444_bases
ATGAGCAGCAACCATTCGCAGAATCCCTACTACTCGCGTACCGACACTACCAAGCTCGATCTCCCGGACGAGGTTTGGAA
AAAGGTGCTCTCGCCCGAACTGTACGCCGTGGCGCGCAAGGGCGAGACCGAGCGGGCATTCACCGGCAAGTATTGGAATT
ACGAGGGGCTCGGCACCTACTACTGCGCGGCCTGTGGGAACGCACTTTTCCGCTCCGACGCCAAGTTTGCCAGCACCTGC
GGCTGGCCGAGCTTTTTCGAGACCGTGCGTCCCGGCAGCGTCGAATATCGGGAAGACAACTCCTACGGCATGATGCGCAC
CGAAGTGCTCTGCGGAAGGTGCGATGCCCATCTCGGCCACGTTTTTGACGATGGCCCGCCGCCCACTGGCAAACGCTTCT
GCATGAACTCGGTCTCGCTGGACTTTGAGCCGGACAGCAATTGA

Upstream 100 bases:

>100_bases
CATGAAACGAATCATTTTACATGTTCCGCTGATCCTGTTTGCGCTTGCCGCTTGCCAGGCTGCGCCGCAAGGATCGACGG
TAACCCAATCCGGAGCCGCC

Downstream 100 bases:

>100_bases
TCATTGACAGTTGATAATGGATAATTGAAAAGGCCGAGCACGGGTTTCGTCCGTTATCCAACTCGTCCGCGCTGTTCAAC
GACACTATTTGCAGGGGCGG

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MSSNHSQNPYYSRTDTTKLDLPDEVWKKVLSPELYAVARKGETERAFTGKYWNYEGLGTYYCAACGNALFRSDAKFASTC
GWPSFFETVRPGSVEYREDNSYGMMRTEVLCGRCDAHLGHVFDDGPPPTGKRFCMNSVSLDFEPDSN

Sequences:

>Translated_147_residues
MSSNHSQNPYYSRTDTTKLDLPDEVWKKVLSPELYAVARKGETERAFTGKYWNYEGLGTYYCAACGNALFRSDAKFASTC
GWPSFFETVRPGSVEYREDNSYGMMRTEVLCGRCDAHLGHVFDDGPPPTGKRFCMNSVSLDFEPDSN
>Mature_146_residues
SSNHSQNPYYSRTDTTKLDLPDEVWKKVLSPELYAVARKGETERAFTGKYWNYEGLGTYYCAACGNALFRSDAKFASTCG
WPSFFETVRPGSVEYREDNSYGMMRTEVLCGRCDAHLGHVFDDGPPPTGKRFCMNSVSLDFEPDSN

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=127, Percent_Identity=45.6692913385827, Blast_Score=131, Evalue=3e-31,
Organism=Homo sapiens, GI301336162, Length=127, Percent_Identity=45.6692913385827, Blast_Score=131, Evalue=3e-31,
Organism=Homo sapiens, GI73089054, Length=127, Percent_Identity=45.6692913385827, Blast_Score=131, Evalue=3e-31,
Organism=Homo sapiens, GI37620216, Length=127, Percent_Identity=45.6692913385827, Blast_Score=130, Evalue=3e-31,
Organism=Homo sapiens, GI117606353, Length=136, Percent_Identity=47.7941176470588, Blast_Score=122, Evalue=8e-29,
Organism=Homo sapiens, GI7706511, Length=99, Percent_Identity=41.4141414141414, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788077, Length=124, Percent_Identity=49.1935483870968, Blast_Score=124, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17553450, Length=126, Percent_Identity=50, Blast_Score=122, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI115532676, Length=126, Percent_Identity=50, Blast_Score=122, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6319816, Length=142, Percent_Identity=38.7323943661972, Blast_Score=109, Evalue=2e-25,
Organism=Drosophila melanogaster, GI221378664, Length=126, Percent_Identity=48.4126984126984, Blast_Score=129, Evalue=9e-31,
Organism=Drosophila melanogaster, GI221378662, Length=133, Percent_Identity=45.8646616541353, Blast_Score=126, Evalue=5e-30,
Organism=Drosophila melanogaster, GI45553335, Length=126, Percent_Identity=45.2380952380952, Blast_Score=119, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21356369, Length=126, Percent_Identity=45.2380952380952, Blast_Score=119, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24645799, Length=126, Percent_Identity=45.2380952380952, Blast_Score=119, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24645804, Length=137, Percent_Identity=41.6058394160584, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24645801, Length=137, Percent_Identity=41.6058394160584, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16602; Mature: 16471

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNHSQNPYYSRTDTTKLDLPDEVWKKVLSPELYAVARKGETERAFTGKYWNYEGLGTY
CCCCCCCCCCCCCCCCEECCCCHHHHHHHHCCHHEEHHCCCCCCCEECCCCCCCCCCCHH
YCAACGNALFRSDAKFASTCGWPSFFETVRPGSVEYREDNSYGMMRTEVLCGRCDAHLGH
HHHHHCHHHHHCCCCHHHHCCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCC
VFDDGPPPTGKRFCMNSVSLDFEPDSN
CCCCCCCCCCHHHHHCCCEEECCCCCC
>Mature Secondary Structure 
SSNHSQNPYYSRTDTTKLDLPDEVWKKVLSPELYAVARKGETERAFTGKYWNYEGLGTY
CCCCCCCCCCCCCCCEECCCCHHHHHHHHCCHHEEHHCCCCCCCEECCCCCCCCCCCHH
YCAACGNALFRSDAKFASTCGWPSFFETVRPGSVEYREDNSYGMMRTEVLCGRCDAHLGH
HHHHHCHHHHHCCCCHHHHCCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCC
VFDDGPPPTGKRFCMNSVSLDFEPDSN
CCCCCCCCCCHHHHHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]