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The map label for this gene is yycG [H]

Identifier: 193214327

GI number: 193214327

Start: 714858

End: 716972

Strand: Direct

Name: yycG [H]

Synonym: Ctha_0609

Alternate gene names: 193214327

Gene position: 714858-716972 (Clockwise)

Preceding gene: 193214326

Following gene: 193214328

Centisome position: 21.71

GC content: 47.09

Gene sequence:

>2115_bases
ATGGAAGAGTTAGCAACCGCAATAAACCATATTGATCACCTTAACCGCCTGGCTTGGCAAGCCTTGCCAAACAATCTAAT
GGACGCGCTTCGCTTGAGCAAAGAAGCCCATTCGCTTTCAAAAAAGTTGAAGTACACCAAAGGTGAAGCTTATAGCCTTT
GCTACGAAGGCCTTGCCACACAATCGCTTGCTGATTTTCGAAAATCGTTACGCGCTTCCATGAGAGCGCTACGCTTATTC
AAACAGCTTGGCGACGATTTTGGCTGCGCGCTTGCGCTGCATAGCATTGGCAATACGTATTATAGCACAGGAAACTATCT
CCGTGCTGAAACCCATTTTGAGGAAAGTCTTCAAATACACAGGAAAACTCATGATGTGGCCGGACAAGCAGACGCCTTGA
ACTCAATTGGCATGGTTCACCAACAGTTAGGCAATTACGCTGAAGCACTTCGATATTATCATAATAGCTTTTTACTTCGC
GAGCAAATGAACGATGTTTTCGGCAAAGTCGCATCGCTCAATCGAATTGGCTCCGTTTTTCAAATGTTGGGCGAAAATCT
CAAAGCGCTTGACTATTTTTTAAAAGCCTTGTCTTTAATTCACGAAATGGAAGATTTGCAACTTGAAGCCGTCGCGCAAT
ACAACATCGGCGCGATTTACGATTCACTCGGCAACTACGATCAGGCTAAAAACTTTTACCTTCAAAGTCTTGAAAAAAAA
GTTCGCGCTTTAGACCACAAAGGCGAAGCGGATGTGCTCAGCAATCTTGGCCATCTCTTCTACGCTCAGAGAGATTATTC
CAGCGCTTTAGAAATGCTTCTCAGAAGCCAGGAACTCAAAAAACGCTTGGGCGACAAAACCGGCGCGGCTATTGCACGCA
AAGACATCGGCACAGTCTACATGGCGCTAAATGATTTTCAAGCGGCTGAAGCGCACTTAACCCAAAGCCTTCAAGAACTT
CAGGAAACCGAACACACGCTTGGCTTGGCGCAAAGCATTCGCGCGTTAGGGCAGCTCTACGCGGAAAGCCTGCAAGCAGA
ACGCGCGATCGCCTACTTTGAGCAAGCGTTGGAAAAGTTTAGCCAGCTTGGCGTTAAGGCTGAAATTCCAGCGACTGCCC
AAGCACTTGCCGAAGCATACGAGTCCATCGGCGATTACAAACAGGCGCTTCACTATTTCAAGATTTATCAAAATAGCCTC
GCACAAATTTCGAACGCGGAAATTGAGGAAAAGCTCAAAACATTGATGATTCAGTTCGATTTGGAAAAAGCACAGCGCGA
GGCTGACCTGTTTCGCACAACCAATCAACAGCTTTCCAAAACCAACCACGCGCTCGAAAAAGCGCTCAAAGAAGCCGAGC
TTCAACGCCAACATGCCATGGAAGCCGATTCGTTCAAAACGGAACTTTTGGGCATCGCCGCGCACGATTTGCGCAGCCCG
CTTCAATCGGTCATCGGATTCAACTCGCTCATCAAAGAGGAAATTGCCCGATTAACACTTGTTCAACCGGACGATCAATT
GCAGCATGTTATTGCGATGAACGGCATTATCGGCAAAACAGCGGCCAGAATGTTGGATTTAATCAACGAGCTCTTGGAAT
CCACCGCTATCGAGTCGGGGAGAATTCAATGCCATCCGCAACCGGTGGACGTGTGCGAAATCATCAAACTAAGCGTTTCG
AGCTTTGAGATTTTGGCGAAAGTCAAGCATCAATCGATCATTTGCCACAATGGCACCAACTGCATTGCCAATGTAGATGC
CAGCCAACTGCGCGAGGTGATCGATAATCTTATCAGCAATGCGATCAAATATTCTCCGCATCATACCACGATTCACATTC
ACGCGCTGAGCAGCGATGGCAACGTGATTTTTTCCATCAAAGACGAAGGGCTTGGCTTGAGCAAAATCGATCTGGAAAAA
GTATTTCAACAGTTCCAGCGACTCAGCGCCAGACCCACCGACAACGAACCATCATTCGGTCTGGGACTTTCCATCGCCAA
ACAACTCGTCGAGCTCAATGGCGGAGAGATTCATGTAGAAAGCGAAGGCAAAAATAAAGGCGCAACCTTTACAGTGAAAT
TCAAAGCGTGTGACGAAACGGTTTCTTTGGGCTAA

Upstream 100 bases:

>100_bases
GAATGACAATGCGCAACCAACAGGGCGTCCAAGCGCATTTTTTTGCTCAACTTTTCTGCGCCATAGGCATCAATTCTGTT
TAGAAACTATTGAGAGAGAA

Downstream 100 bases:

>100_bases
ATATTCACGAAACTGGTCAGAAATGCCTAAATTTTCGCGTGCATCATTTTTCGCATTTTAAACCAAACATCTTTCGGGAT
AAAAGCTTGATGGAGGAAAC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 704

Protein sequence:

>704_residues
MEELATAINHIDHLNRLAWQALPNNLMDALRLSKEAHSLSKKLKYTKGEAYSLCYEGLATQSLADFRKSLRASMRALRLF
KQLGDDFGCALALHSIGNTYYSTGNYLRAETHFEESLQIHRKTHDVAGQADALNSIGMVHQQLGNYAEALRYYHNSFLLR
EQMNDVFGKVASLNRIGSVFQMLGENLKALDYFLKALSLIHEMEDLQLEAVAQYNIGAIYDSLGNYDQAKNFYLQSLEKK
VRALDHKGEADVLSNLGHLFYAQRDYSSALEMLLRSQELKKRLGDKTGAAIARKDIGTVYMALNDFQAAEAHLTQSLQEL
QETEHTLGLAQSIRALGQLYAESLQAERAIAYFEQALEKFSQLGVKAEIPATAQALAEAYESIGDYKQALHYFKIYQNSL
AQISNAEIEEKLKTLMIQFDLEKAQREADLFRTTNQQLSKTNHALEKALKEAELQRQHAMEADSFKTELLGIAAHDLRSP
LQSVIGFNSLIKEEIARLTLVQPDDQLQHVIAMNGIIGKTAARMLDLINELLESTAIESGRIQCHPQPVDVCEIIKLSVS
SFEILAKVKHQSIICHNGTNCIANVDASQLREVIDNLISNAIKYSPHHTTIHIHALSSDGNVIFSIKDEGLGLSKIDLEK
VFQQFQRLSARPTDNEPSFGLGLSIAKQLVELNGGEIHVESEGKNKGATFTVKFKACDETVSLG

Sequences:

>Translated_704_residues
MEELATAINHIDHLNRLAWQALPNNLMDALRLSKEAHSLSKKLKYTKGEAYSLCYEGLATQSLADFRKSLRASMRALRLF
KQLGDDFGCALALHSIGNTYYSTGNYLRAETHFEESLQIHRKTHDVAGQADALNSIGMVHQQLGNYAEALRYYHNSFLLR
EQMNDVFGKVASLNRIGSVFQMLGENLKALDYFLKALSLIHEMEDLQLEAVAQYNIGAIYDSLGNYDQAKNFYLQSLEKK
VRALDHKGEADVLSNLGHLFYAQRDYSSALEMLLRSQELKKRLGDKTGAAIARKDIGTVYMALNDFQAAEAHLTQSLQEL
QETEHTLGLAQSIRALGQLYAESLQAERAIAYFEQALEKFSQLGVKAEIPATAQALAEAYESIGDYKQALHYFKIYQNSL
AQISNAEIEEKLKTLMIQFDLEKAQREADLFRTTNQQLSKTNHALEKALKEAELQRQHAMEADSFKTELLGIAAHDLRSP
LQSVIGFNSLIKEEIARLTLVQPDDQLQHVIAMNGIIGKTAARMLDLINELLESTAIESGRIQCHPQPVDVCEIIKLSVS
SFEILAKVKHQSIICHNGTNCIANVDASQLREVIDNLISNAIKYSPHHTTIHIHALSSDGNVIFSIKDEGLGLSKIDLEK
VFQQFQRLSARPTDNEPSFGLGLSIAKQLVELNGGEIHVESEGKNKGATFTVKFKACDETVSLG
>Mature_704_residues
MEELATAINHIDHLNRLAWQALPNNLMDALRLSKEAHSLSKKLKYTKGEAYSLCYEGLATQSLADFRKSLRASMRALRLF
KQLGDDFGCALALHSIGNTYYSTGNYLRAETHFEESLQIHRKTHDVAGQADALNSIGMVHQQLGNYAEALRYYHNSFLLR
EQMNDVFGKVASLNRIGSVFQMLGENLKALDYFLKALSLIHEMEDLQLEAVAQYNIGAIYDSLGNYDQAKNFYLQSLEKK
VRALDHKGEADVLSNLGHLFYAQRDYSSALEMLLRSQELKKRLGDKTGAAIARKDIGTVYMALNDFQAAEAHLTQSLQEL
QETEHTLGLAQSIRALGQLYAESLQAERAIAYFEQALEKFSQLGVKAEIPATAQALAEAYESIGDYKQALHYFKIYQNSL
AQISNAEIEEKLKTLMIQFDLEKAQREADLFRTTNQQLSKTNHALEKALKEAELQRQHAMEADSFKTELLGIAAHDLRSP
LQSVIGFNSLIKEEIARLTLVQPDDQLQHVIAMNGIIGKTAARMLDLINELLESTAIESGRIQCHPQPVDVCEIIKLSVS
SFEILAKVKHQSIICHNGTNCIANVDASQLREVIDNLISNAIKYSPHHTTIHIHALSSDGNVIFSIKDEGLGLSKIDLEK
VFQQFQRLSARPTDNEPSFGLGLSIAKQLVELNGGEIHVESEGKNKGATFTVKFKACDETVSLG

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Homo sapiens, GI224028289, Length=391, Percent_Identity=25.3196930946292, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI164519122, Length=286, Percent_Identity=25.5244755244755, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI224548927, Length=296, Percent_Identity=23.6486486486486, Blast_Score=90, Evalue=9e-18,
Organism=Homo sapiens, GI224548925, Length=296, Percent_Identity=23.6486486486486, Blast_Score=88, Evalue=3e-17,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=27.6, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1789149, Length=255, Percent_Identity=30.5882352941176, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI145693157, Length=255, Percent_Identity=27.843137254902, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI48994928, Length=259, Percent_Identity=25.0965250965251, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI87081816, Length=294, Percent_Identity=24.1496598639456, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1786912, Length=265, Percent_Identity=27.1698113207547, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=25.5605381165919, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=29.0909090909091, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24660950, Length=355, Percent_Identity=22.8169014084507, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24650658, Length=294, Percent_Identity=26.1904761904762, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78598; Mature: 78598

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEELATAINHIDHLNRLAWQALPNNLMDALRLSKEAHSLSKKLKYTKGEAYSLCYEGLAT
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QSLADFRKSLRASMRALRLFKQLGDDFGCALALHSIGNTYYSTGNYLRAETHFEESLQIH
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEECCCCEEEEHHHHHHHHHHH
RKTHDVAGQADALNSIGMVHQQLGNYAEALRYYHNSFLLREQMNDVFGKVASLNRIGSVF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMLGENLKALDYFLKALSLIHEMEDLQLEAVAQYNIGAIYDSLGNYDQAKNFYLQSLEKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHH
VRALDHKGEADVLSNLGHLFYAQRDYSSALEMLLRSQELKKRLGDKTGAAIARKDIGTVY
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCHHHHHHHHHHHE
MALNDFQAAEAHLTQSLQELQETEHTLGLAQSIRALGQLYAESLQAERAIAYFEQALEKF
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLGVKAEIPATAQALAEAYESIGDYKQALHYFKIYQNSLAQISNAEIEEKLKTLMIQFD
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LEKAQREADLFRTTNQQLSKTNHALEKALKEAELQRQHAMEADSFKTELLGIAAHDLRSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LQSVIGFNSLIKEEIARLTLVQPDDQLQHVIAMNGIIGKTAARMLDLINELLESTAIESG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
RIQCHPQPVDVCEIIKLSVSSFEILAKVKHQSIICHNGTNCIANVDASQLREVIDNLISN
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCEECCCHHHHHHHHHHHHHH
AIKYSPHHTTIHIHALSSDGNVIFSIKDEGLGLSKIDLEKVFQQFQRLSARPTDNEPSFG
HHCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
LGLSIAKQLVELNGGEIHVESEGKNKGATFTVKFKACDETVSLG
HHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEEECCCHHCCC
>Mature Secondary Structure
MEELATAINHIDHLNRLAWQALPNNLMDALRLSKEAHSLSKKLKYTKGEAYSLCYEGLAT
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QSLADFRKSLRASMRALRLFKQLGDDFGCALALHSIGNTYYSTGNYLRAETHFEESLQIH
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEECCCCEEEEHHHHHHHHHHH
RKTHDVAGQADALNSIGMVHQQLGNYAEALRYYHNSFLLREQMNDVFGKVASLNRIGSVF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMLGENLKALDYFLKALSLIHEMEDLQLEAVAQYNIGAIYDSLGNYDQAKNFYLQSLEKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHH
VRALDHKGEADVLSNLGHLFYAQRDYSSALEMLLRSQELKKRLGDKTGAAIARKDIGTVY
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCHHHHHHHHHHHE
MALNDFQAAEAHLTQSLQELQETEHTLGLAQSIRALGQLYAESLQAERAIAYFEQALEKF
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLGVKAEIPATAQALAEAYESIGDYKQALHYFKIYQNSLAQISNAEIEEKLKTLMIQFD
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LEKAQREADLFRTTNQQLSKTNHALEKALKEAELQRQHAMEADSFKTELLGIAAHDLRSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LQSVIGFNSLIKEEIARLTLVQPDDQLQHVIAMNGIIGKTAARMLDLINELLESTAIESG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
RIQCHPQPVDVCEIIKLSVSSFEILAKVKHQSIICHNGTNCIANVDASQLREVIDNLISN
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCEECCCHHHHHHHHHHHHHH
AIKYSPHHTTIHIHALSSDGNVIFSIKDEGLGLSKIDLEKVFQQFQRLSARPTDNEPSFG
HHCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
LGLSIAKQLVELNGGEIHVESEGKNKGATFTVKFKACDETVSLG
HHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]