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The map label for this gene is pdxH [H]

Identifier: 193214326

GI number: 193214326

Start: 713897

End: 714532

Strand: Direct

Name: pdxH [H]

Synonym: Ctha_0608

Alternate gene names: 193214326

Gene position: 713897-714532 (Clockwise)

Preceding gene: 193214324

Following gene: 193214327

Centisome position: 21.68

GC content: 49.37

Gene sequence:

>636_bases
ATGACCTTAGCAGAAAAACGAAAAGAGTATGGCGAAAAAAATTTGGCGCGCGGCGATCTGGCATCAGATCCCATTTCGCA
GTTTGGCGTGTGGCTTCAGCAAGCCATTGACACCAATTTGAGCGAGCCAAATGCAATGACGCTGGCCACCGTTGGAAAAA
GCGCAAAGCCAACTGCGAGAACCGTTTTATTAAAAGGATTTGACCATCGCGGATTCTTTTTTTTCACGAACTACGAAAGC
CGAAAAGGCCAAGATCTTTCGGAGAATCCTTATGCTGCGATTGTCTTTTTTTGGAGAGAGCTGGAAAGGCAAGTAACCGC
TACCGGGAAAGTGTCCAAAATTAGCCGTGAGGAATCGGCGGAATACTTTGCGAAAAGACCGCTTGGCAGCCGATTGGGCG
CTTGGGCATCGAGGCAAAGCACGCCAATCGAAACTCGCGACATCTTGGAAGCGCGCTTTGACGCATATCAAAAACAGTTT
GGCGAGGCCGTTCCGCTACCTGATTTTTGGGGCGGATTTTGCCTTGAGCCCGAAACCGTTGAGTTTTGGCAAGGCCGTGC
AAACCGCTTGCACGATCGGTTTCAATATGCCCGAATTGCACCCGAAATTTGGAAGCTGGAAAGACTTTCGCCTTAA

Upstream 100 bases:

>100_bases
TTATGCTAAACTTATGCTGAGGCGCAAAACCTATGCTGTTTCTCACAAATAGATTGACCTTTGTCTCTGTATATTTTCCA
CAGTTTTGATCGTTTGACCA

Downstream 100 bases:

>100_bases
ATGCACGCTTTTCCTTTTCACCCAAAAAAGATACATAACGGTTTCTGGAGGTTTATTTTCCAAACTGATTGCGTTGGCAT
TGGGGTCAAACGCGGCTGTC

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MTLAEKRKEYGEKNLARGDLASDPISQFGVWLQQAIDTNLSEPNAMTLATVGKSAKPTARTVLLKGFDHRGFFFFTNYES
RKGQDLSENPYAAIVFFWRELERQVTATGKVSKISREESAEYFAKRPLGSRLGAWASRQSTPIETRDILEARFDAYQKQF
GEAVPLPDFWGGFCLEPETVEFWQGRANRLHDRFQYARIAPEIWKLERLSP

Sequences:

>Translated_211_residues
MTLAEKRKEYGEKNLARGDLASDPISQFGVWLQQAIDTNLSEPNAMTLATVGKSAKPTARTVLLKGFDHRGFFFFTNYES
RKGQDLSENPYAAIVFFWRELERQVTATGKVSKISREESAEYFAKRPLGSRLGAWASRQSTPIETRDILEARFDAYQKQF
GEAVPLPDFWGGFCLEPETVEFWQGRANRLHDRFQYARIAPEIWKLERLSP
>Mature_210_residues
TLAEKRKEYGEKNLARGDLASDPISQFGVWLQQAIDTNLSEPNAMTLATVGKSAKPTARTVLLKGFDHRGFFFFTNYESR
KGQDLSENPYAAIVFFWRELERQVTATGKVSKISREESAEYFAKRPLGSRLGAWASRQSTPIETRDILEARFDAYQKQFG
EAVPLPDFWGGFCLEPETVEFWQGRANRLHDRFQYARIAPEIWKLERLSP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=236, Percent_Identity=41.1016949152542, Blast_Score=176, Evalue=2e-44,
Organism=Escherichia coli, GI1787926, Length=210, Percent_Identity=45.2380952380952, Blast_Score=196, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI17553712, Length=198, Percent_Identity=39.8989898989899, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6319509, Length=217, Percent_Identity=41.4746543778802, Blast_Score=167, Evalue=9e-43,
Organism=Drosophila melanogaster, GI45551845, Length=228, Percent_Identity=39.4736842105263, Blast_Score=153, Evalue=8e-38,
Organism=Drosophila melanogaster, GI24644901, Length=228, Percent_Identity=39.4736842105263, Blast_Score=153, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24644903, Length=171, Percent_Identity=28.0701754385965, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 24207; Mature: 24075

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAEKRKEYGEKNLARGDLASDPISQFGVWLQQAIDTNLSEPNAMTLATVGKSAKPTAR
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHH
TVLLKGFDHRGFFFFTNYESRKGQDLSENPYAAIVFFWRELERQVTATGKVSKISREESA
HHEEECCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EYFAKRPLGSRLGAWASRQSTPIETRDILEARFDAYQKQFGEAVPLPDFWGGFCLEPETV
HHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
EFWQGRANRLHDRFQYARIAPEIWKLERLSP
HHHCCHHHHHHHHHHHHHHCHHHHHHHCCCC
>Mature Secondary Structure 
TLAEKRKEYGEKNLARGDLASDPISQFGVWLQQAIDTNLSEPNAMTLATVGKSAKPTAR
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHH
TVLLKGFDHRGFFFFTNYESRKGQDLSENPYAAIVFFWRELERQVTATGKVSKISREESA
HHEEECCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EYFAKRPLGSRLGAWASRQSTPIETRDILEARFDAYQKQFGEAVPLPDFWGGFCLEPETV
HHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
EFWQGRANRLHDRFQYARIAPEIWKLERLSP
HHHCCHHHHHHHHHHHHHHCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA