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The map label for this gene is trpS [H]

Identifier: 193214236

GI number: 193214236

Start: 613948

End: 614946

Strand: Direct

Name: trpS [H]

Synonym: Ctha_0517

Alternate gene names: 193214236

Gene position: 613948-614946 (Clockwise)

Preceding gene: 193214235

Following gene: 193214237

Centisome position: 18.64

GC content: 48.85

Gene sequence:

>999_bases
ATGGAAAAAATTGCCCTAACGGGAATTAAACCAACCGGAACGCCTCACGTTGGAAACTACCTCGGCGCTATTTTGCCGGC
GCTTGAACTTGCTGAAAAATACCGTGCTTTTTATTTCATCGCTGATTACCACGCGCTCACCACCGTTCGCGATGGCAAGC
AGCTTCAAGAACTCACCTACGAGGTTGCGGCCACTTGGCTGGCGCTGGGTCTCGATCATGAAAAAGTCACTTTTTTCCGC
CAATCCGAAGTACCGGAACTTTTCGAGTTGCAATGGATTCTTTCGTGCAACACACCCAAAGGGCTTTTGAATCGCGCACA
TGCCTACAAGGCCGCCGTAGATCAAAACGTGGCTGCCGAAAAAGACCCAGACTTCGGCGTGAACGCCGGCCTTTTCAACT
ATCCCGTTTTGATGGCAAGCGATATTTTGATGTTTGGGACAAACATTGTTCCCGTCGGCTTAGACCAAAAGCAGCACATC
GAAATCGCCCGTGATATTGCTGAAAATTTCAATAACACGTTTGGCGACATTTTGACCATGCCGGAAGGATTGATTCAAGA
AGATTTGATGACCATTCCGGGCACAGATGGCCGCAAAATGAGCAAGAATTATAACAACACTTTGCCGCTCTTTTTTCCAT
CGAAGCAATTGCGCAAGCGCGTGATGCAAATTCAAACGGATTCAAAAACGGTTGAAGAGCCGAAAAATCCTGATGAATGT
AATGTGTTTGCCATTTATCGGCGATTTGCCACGCCGGAGCAAATCGCAGACATGCGCGCGCGCTACGAAAAAGGTGGCTT
GGGTTATGGAACGGCCAAGCAAGAATTGTTTGAACTTCTGGAAGCGCGTTTTGGCCAGCAGCGCGAAAAATACGAGTCGC
TCATGGCAAACAAAGCTGAGATAGATAGCATCCTGTTAGCTGGCGCTGAAAAAGCACGCGCCGTTTCTCGCCCAATGATA
CACAAAGTCCGACAAGCGATTGGGGCACGGCCTCGCTAA

Upstream 100 bases:

>100_bases
GCAAAAAGTTACTTTTATTTGAACCCTGTTAGATGGACGAACATGGAGAAAAATCACATAAAAACGGCTGCTCCTTTGCC
GCAACGAATTAACTTTTCAA

Downstream 100 bases:

>100_bases
ACACAACCAAAAGGCGTTCCATTTTAGAGCGCCACGCTTGCATAAGGACAAAATGCGTTTGCTTTTCATCTTTGAAATCA
TTGCAAGAAAAAATCATTTA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MEKIALTGIKPTGTPHVGNYLGAILPALELAEKYRAFYFIADYHALTTVRDGKQLQELTYEVAATWLALGLDHEKVTFFR
QSEVPELFELQWILSCNTPKGLLNRAHAYKAAVDQNVAAEKDPDFGVNAGLFNYPVLMASDILMFGTNIVPVGLDQKQHI
EIARDIAENFNNTFGDILTMPEGLIQEDLMTIPGTDGRKMSKNYNNTLPLFFPSKQLRKRVMQIQTDSKTVEEPKNPDEC
NVFAIYRRFATPEQIADMRARYEKGGLGYGTAKQELFELLEARFGQQREKYESLMANKAEIDSILLAGAEKARAVSRPMI
HKVRQAIGARPR

Sequences:

>Translated_332_residues
MEKIALTGIKPTGTPHVGNYLGAILPALELAEKYRAFYFIADYHALTTVRDGKQLQELTYEVAATWLALGLDHEKVTFFR
QSEVPELFELQWILSCNTPKGLLNRAHAYKAAVDQNVAAEKDPDFGVNAGLFNYPVLMASDILMFGTNIVPVGLDQKQHI
EIARDIAENFNNTFGDILTMPEGLIQEDLMTIPGTDGRKMSKNYNNTLPLFFPSKQLRKRVMQIQTDSKTVEEPKNPDEC
NVFAIYRRFATPEQIADMRARYEKGGLGYGTAKQELFELLEARFGQQREKYESLMANKAEIDSILLAGAEKARAVSRPMI
HKVRQAIGARPR
>Mature_332_residues
MEKIALTGIKPTGTPHVGNYLGAILPALELAEKYRAFYFIADYHALTTVRDGKQLQELTYEVAATWLALGLDHEKVTFFR
QSEVPELFELQWILSCNTPKGLLNRAHAYKAAVDQNVAAEKDPDFGVNAGLFNYPVLMASDILMFGTNIVPVGLDQKQHI
EIARDIAENFNNTFGDILTMPEGLIQEDLMTIPGTDGRKMSKNYNNTLPLFFPSKQLRKRVMQIQTDSKTVEEPKNPDEC
NVFAIYRRFATPEQIADMRARYEKGGLGYGTAKQELFELLEARFGQQREKYESLMANKAEIDSILLAGAEKARAVSRPMI
HKVRQAIGARPR

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=336, Percent_Identity=28.5714285714286, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI41352700, Length=185, Percent_Identity=38.9189189189189, Blast_Score=135, Evalue=6e-32,
Organism=Escherichia coli, GI1789786, Length=342, Percent_Identity=34.5029239766082, Blast_Score=189, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71982800, Length=344, Percent_Identity=28.4883720930233, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71982793, Length=339, Percent_Identity=28.023598820059, Blast_Score=126, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320474, Length=344, Percent_Identity=32.2674418604651, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24666151, Length=334, Percent_Identity=30.5389221556886, Blast_Score=121, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37389; Mature: 37389

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIALTGIKPTGTPHVGNYLGAILPALELAEKYRAFYFIADYHALTTVRDGKQLQELTY
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHCHHHHHHHHH
EVAATWLALGLDHEKVTFFRQSEVPELFELQWILSCNTPKGLLNRAHAYKAAVDQNVAAE
HHHHHHHHHCCCCHHHEEECCCCCCHHHHEEEEEECCCCHHHHHHHHHHHHHHHCCCCCC
KDPDFGVNAGLFNYPVLMASDILMFGTNIVPVGLDQKQHIEIARDIAENFNNTFGDILTM
CCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHC
PEGLIQEDLMTIPGTDGRKMSKNYNNTLPLFFPSKQLRKRVMQIQTDSKTVEEPKNPDEC
CHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEECCHHHHHHHHHHHCCCHHHCCCCCCCCC
NVFAIYRRFATPEQIADMRARYEKGGLGYGTAKQELFELLEARFGQQREKYESLMANKAE
CHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCHHH
IDSILLAGAEKARAVSRPMIHKVRQAIGARPR
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEKIALTGIKPTGTPHVGNYLGAILPALELAEKYRAFYFIADYHALTTVRDGKQLQELTY
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHCHHHHHHHHH
EVAATWLALGLDHEKVTFFRQSEVPELFELQWILSCNTPKGLLNRAHAYKAAVDQNVAAE
HHHHHHHHHCCCCHHHEEECCCCCCHHHHEEEEEECCCCHHHHHHHHHHHHHHHCCCCCC
KDPDFGVNAGLFNYPVLMASDILMFGTNIVPVGLDQKQHIEIARDIAENFNNTFGDILTM
CCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHC
PEGLIQEDLMTIPGTDGRKMSKNYNNTLPLFFPSKQLRKRVMQIQTDSKTVEEPKNPDEC
CHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEECCHHHHHHHHHHHCCCHHHCCCCCCCCC
NVFAIYRRFATPEQIADMRARYEKGGLGYGTAKQELFELLEARFGQQREKYESLMANKAE
CHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCHHH
IDSILLAGAEKARAVSRPMIHKVRQAIGARPR
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]