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The map label for this gene is etfD [H]

Identifier: 193214191

GI number: 193214191

Start: 554786

End: 556489

Strand: Direct

Name: etfD [H]

Synonym: Ctha_0472

Alternate gene names: 193214191

Gene position: 554786-556489 (Clockwise)

Preceding gene: 193214187

Following gene: 193214195

Centisome position: 16.85

GC content: 47.83

Gene sequence:

>1704_bases
ATGAGTCTTCAACCACAGATAGAACGAGAAACTTTGGAAATGGACGTGCTATTTGTCGGTGCAGGACCGGCAAATTTAGC
GGCGGCCATTCGTCTAAAGCAATTGATTGATAAACATAACGAAACGGCATCGGAAAAACTCGACCCGGAAATTGCACTTA
TAGAAAAAGGAAAGTCCGTTGGTGCGCATTTGCTCTCCGGCGCGATTTTGGACACGCGCGCGCTCAAAGAGCTCATTCCC
GATTACATAGAAAAAAATTGCCCGATTGAAGCAACAGTCGAACAGGAACGCGTGTTTTTCCTCACGGAGGAAAAAAAGTT
CAACATGCCTTTTTTACCCGCGAGTTTCAAAAATCATGGCTCACCGCTTATTTCTTTAAGCAAGTTTGGAAAATGGCTTG
GAAAAATGGCTGAGGAAATGGGAATTAACCTGTTTGAAGGCATTGCAGGAGCAGAACCCATCATTGAAAACGGGCAGGTG
CTGGGCGTTCGCACCGACGACAAAGGACGCGACAAAAACGGCCAGCCGAAACCAAACTTTGAGCCAGGCATGAACATTCA
TGCCAAAGTGACCGTTTTGGGCGAAGGCGCGCGCGGCTCGCTGACGAAAAAAATCGCGCGGCAGCTCAGCCTCGAAGCCG
ATGCAACGCCGCAAGCCTACGAAACTGGCGTGAAAGAAATTTGGGAAATTCCATCGGGACGAATAAAAAAAGGAACGGCG
ATTCATAGCTTTGGATTTCCGCTGCCCGCCACGATTTACGGCGGCGGCTGGATTTATGCCCTGTCTGAAACGCGCCTTTC
CATTGGCTTTGTCACGGCGCTCGACGCTGCCGATCCAACAAACGATCCGCACTTCAATTTGCAACGCTTCAAAACACATC
CTTTTGTTCGCGAGCTTTTGAACGGCGGAACCTTGATCGGCTATGGCGCAAAGGCAATTTCCGGCGGCGGCTATGCGTCG
ATACCAAAGCTGTTTGCAAACGGCCTTTTGCTTACAGGCGAATCAGGCGGATTTTTAAATTCCATGCGGCTAAAAGGCAT
TCATCTCAGCATGAAATCAGGCATGCTCGCCGCCGAAACCATTTTCGACGCATTGAAAAAAAAGGATTTCTCAGAGGAAA
CGTTGAAAACCTATCGAGAGGCTTTTGAACAATCCTGGGCGAAAGAGGAACTCTATGAAGTTCGCAATTTTCGGCAAGCA
TTTAATTATGGGCTTTATTCGGGCGCGATTCGCGTTGGCTTGCAGCAACTCTTCAGCGGACGCTTGGTGGCGAAGCAACT
GGATCACGATCCCGATCACATGCAAATGGAGCATTTCCATCGATTGCATCGCGCTCGCTATCTTGAAGTAAAAGCTGATT
TCAAATATGATGGGAAATTAACCTTCGATAAGCTCACGGATTTGTATGAATCAGGCACGACTCACGAGGAAAATCAACCG
TGCCATTTGTTCATTGTCCCGGATCTCATCACCGATATTTGCAATACCAAATGTACTGTTGAATATGGGAATCCTTGCCA
ATTTTTTTGTCCGGCAAAAGTCTACGAAATGGTGGTAACTGACGAAAAAATGGGGACAAAAAAGCTACATCTTAATCCGG
CTAATTGCGTGCATTGCAAAACTTGCGACATCGCCGATCCTTATCAAGTCATCACTTGGAAAGTGCCGGAAGGCGGCGGC
GGGCCTAATTATAACAAGGGCTGA

Upstream 100 bases:

>100_bases
TTTAAAATATAACAAACCCCTCTCAAAATCTTTTGGATTCCACTGGGTTCAATTATTTTTCACCCCAATTTCCTAAATCA
ATAAAAAATAAACGTTAGTC

Downstream 100 bases:

>100_bases
TGCTTATTTTTTGAGATAAAAAAGGCGAAGCGACCAGGAAAAGTCGCTTCGCCCCAAAAAAAGAGAAAGAGAAAAGCAAA
TTGCGCTTTTTAGAAGCCGT

Product: electron-transferring-flavoprotein dehydrogenase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MSLQPQIERETLEMDVLFVGAGPANLAAAIRLKQLIDKHNETASEKLDPEIALIEKGKSVGAHLLSGAILDTRALKELIP
DYIEKNCPIEATVEQERVFFLTEEKKFNMPFLPASFKNHGSPLISLSKFGKWLGKMAEEMGINLFEGIAGAEPIIENGQV
LGVRTDDKGRDKNGQPKPNFEPGMNIHAKVTVLGEGARGSLTKKIARQLSLEADATPQAYETGVKEIWEIPSGRIKKGTA
IHSFGFPLPATIYGGGWIYALSETRLSIGFVTALDAADPTNDPHFNLQRFKTHPFVRELLNGGTLIGYGAKAISGGGYAS
IPKLFANGLLLTGESGGFLNSMRLKGIHLSMKSGMLAAETIFDALKKKDFSEETLKTYREAFEQSWAKEELYEVRNFRQA
FNYGLYSGAIRVGLQQLFSGRLVAKQLDHDPDHMQMEHFHRLHRARYLEVKADFKYDGKLTFDKLTDLYESGTTHEENQP
CHLFIVPDLITDICNTKCTVEYGNPCQFFCPAKVYEMVVTDEKMGTKKLHLNPANCVHCKTCDIADPYQVITWKVPEGGG
GPNYNKG

Sequences:

>Translated_567_residues
MSLQPQIERETLEMDVLFVGAGPANLAAAIRLKQLIDKHNETASEKLDPEIALIEKGKSVGAHLLSGAILDTRALKELIP
DYIEKNCPIEATVEQERVFFLTEEKKFNMPFLPASFKNHGSPLISLSKFGKWLGKMAEEMGINLFEGIAGAEPIIENGQV
LGVRTDDKGRDKNGQPKPNFEPGMNIHAKVTVLGEGARGSLTKKIARQLSLEADATPQAYETGVKEIWEIPSGRIKKGTA
IHSFGFPLPATIYGGGWIYALSETRLSIGFVTALDAADPTNDPHFNLQRFKTHPFVRELLNGGTLIGYGAKAISGGGYAS
IPKLFANGLLLTGESGGFLNSMRLKGIHLSMKSGMLAAETIFDALKKKDFSEETLKTYREAFEQSWAKEELYEVRNFRQA
FNYGLYSGAIRVGLQQLFSGRLVAKQLDHDPDHMQMEHFHRLHRARYLEVKADFKYDGKLTFDKLTDLYESGTTHEENQP
CHLFIVPDLITDICNTKCTVEYGNPCQFFCPAKVYEMVVTDEKMGTKKLHLNPANCVHCKTCDIADPYQVITWKVPEGGG
GPNYNKG
>Mature_566_residues
SLQPQIERETLEMDVLFVGAGPANLAAAIRLKQLIDKHNETASEKLDPEIALIEKGKSVGAHLLSGAILDTRALKELIPD
YIEKNCPIEATVEQERVFFLTEEKKFNMPFLPASFKNHGSPLISLSKFGKWLGKMAEEMGINLFEGIAGAEPIIENGQVL
GVRTDDKGRDKNGQPKPNFEPGMNIHAKVTVLGEGARGSLTKKIARQLSLEADATPQAYETGVKEIWEIPSGRIKKGTAI
HSFGFPLPATIYGGGWIYALSETRLSIGFVTALDAADPTNDPHFNLQRFKTHPFVRELLNGGTLIGYGAKAISGGGYASI
PKLFANGLLLTGESGGFLNSMRLKGIHLSMKSGMLAAETIFDALKKKDFSEETLKTYREAFEQSWAKEELYEVRNFRQAF
NYGLYSGAIRVGLQQLFSGRLVAKQLDHDPDHMQMEHFHRLHRARYLEVKADFKYDGKLTFDKLTDLYESGTTHEENQPC
HLFIVPDLITDICNTKCTVEYGNPCQFFCPAKVYEMVVTDEKMGTKKLHLNPANCVHCKTCDIADPYQVITWKVPEGGGG
PNYNKG

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=570, Percent_Identity=41.4035087719298, Blast_Score=418, Evalue=1e-117,
Organism=Escherichia coli, GI1786227, Length=383, Percent_Identity=29.5039164490862, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1787991, Length=396, Percent_Identity=27.7777777777778, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87082155, Length=348, Percent_Identity=26.7241379310345, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25144720, Length=567, Percent_Identity=40.5643738977072, Blast_Score=403, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6324932, Length=580, Percent_Identity=38.1034482758621, Blast_Score=353, Evalue=5e-98,
Organism=Drosophila melanogaster, GI24652256, Length=569, Percent_Identity=41.4762741652021, Blast_Score=405, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 62909; Mature: 62778

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQPQIERETLEMDVLFVGAGPANLAAAIRLKQLIDKHNETASEKLDPEIALIEKGKSV
CCCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEECCCHH
GAHLLSGAILDTRALKELIPDYIEKNCPIEATVEQERVFFLTEEKKFNMPFLPASFKNHG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCC
SPLISLSKFGKWLGKMAEEMGINLFEGIAGAEPIIENGQVLGVRTDDKGRDKNGQPKPNF
CCEEEHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHCCCEEEEEECCCCCCCCCCCCCCCC
EPGMNIHAKVTVLGEGARGSLTKKIARQLSLEADATPQAYETGVKEIWEIPSGRIKKGTA
CCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCE
IHSFGFPLPATIYGGGWIYALSETRLSIGFVTALDAADPTNDPHFNLQRFKTHPFVRELL
EEECCCCCCCEEECCEEEEEEECCEEEEEEEEEECCCCCCCCCCCCHHHHCCCHHHHHHH
NGGTLIGYGAKAISGGGYASIPKLFANGLLLTGESGGFLNSMRLKGIHLSMKSGMLAAET
CCCEEEECCCCEECCCCCHHHHHHHHCCEEEECCCCCCEECEEEEEEEEEHHCCCHHHHH
IFDALKKKDFSEETLKTYREAFEQSWAKEELYEVRNFRQAFNYGLYSGAIRVGLQQLFSG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
RLVAKQLDHDPDHMQMEHFHRLHRARYLEVKADFKYDGKLTFDKLTDLYESGTTHEENQP
CHHHHHCCCCCCHHHHHHHHHHHHCEEEEEEECCEECCEEEHHHHHHHHHCCCCCCCCCC
CHLFIVPDLITDICNTKCTVEYGNPCQFFCPAKVYEMVVTDEKMGTKKLHLNPANCVHCK
EEEEECHHHHHHHHCCEEEEEECCCCEEECHHHHHHHHCCCCCCCCEEEECCCCCEEEEE
TCDIADPYQVITWKVPEGGGGPNYNKG
ECCCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SLQPQIERETLEMDVLFVGAGPANLAAAIRLKQLIDKHNETASEKLDPEIALIEKGKSV
CCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEECCCHH
GAHLLSGAILDTRALKELIPDYIEKNCPIEATVEQERVFFLTEEKKFNMPFLPASFKNHG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCC
SPLISLSKFGKWLGKMAEEMGINLFEGIAGAEPIIENGQVLGVRTDDKGRDKNGQPKPNF
CCEEEHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHCCCEEEEEECCCCCCCCCCCCCCCC
EPGMNIHAKVTVLGEGARGSLTKKIARQLSLEADATPQAYETGVKEIWEIPSGRIKKGTA
CCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCE
IHSFGFPLPATIYGGGWIYALSETRLSIGFVTALDAADPTNDPHFNLQRFKTHPFVRELL
EEECCCCCCCEEECCEEEEEEECCEEEEEEEEEECCCCCCCCCCCCHHHHCCCHHHHHHH
NGGTLIGYGAKAISGGGYASIPKLFANGLLLTGESGGFLNSMRLKGIHLSMKSGMLAAET
CCCEEEECCCCEECCCCCHHHHHHHHCCEEEECCCCCCEECEEEEEEEEEHHCCCHHHHH
IFDALKKKDFSEETLKTYREAFEQSWAKEELYEVRNFRQAFNYGLYSGAIRVGLQQLFSG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
RLVAKQLDHDPDHMQMEHFHRLHRARYLEVKADFKYDGKLTFDKLTDLYESGTTHEENQP
CHHHHHCCCCCCHHHHHHHHHHHHCEEEEEEECCEECCEEEHHHHHHHHHCCCCCCCCCC
CHLFIVPDLITDICNTKCTVEYGNPCQFFCPAKVYEMVVTDEKMGTKKLHLNPANCVHCK
EEEEECHHHHHHHHCCEEEEEECCCCEEECHHHHHHHHCCCCCCCCEEEECCCCCEEEEE
TCDIADPYQVITWKVPEGGGGPNYNKG
ECCCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]