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The map label for this gene is udg [H]

Identifier: 193213923

GI number: 193213923

Start: 238037

End: 239359

Strand: Direct

Name: udg [H]

Synonym: Ctha_0204

Alternate gene names: 193213923

Gene position: 238037-239359 (Clockwise)

Preceding gene: 193213922

Following gene: 193213924

Centisome position: 7.23

GC content: 44.82

Gene sequence:

>1323_bases
ATGAAACATGTTGCAGTTGTAGGAACCGGCTATGTTGGCTTAGTTGCCGGAACCTGTTTTGCCGAAACCGGCAACCAAGT
GATCTGTGTCGATATCGATAAAGCGAAAGTTGAGAAACTCAGAAATAACGTGGTTACGATATATGAACCAGGTCTTGAGG
TGCTTTTCAAACGGAATTTGCGTGAAAAACGCCTTCACTTCACCACAGAACTTGCTGAGGCAATGGAAAGTTGCGACATT
ATTTTTCTTGCCTTGCCAACACCTCCAGGAGAAGACGGCTCTGCAGATTTGAAGTACGTGCTCGGCGTTGCAAAAGAAAT
CGGAAAATTAATCAAGTCATATAAAGTGGTTGTCAACAAAAGCACCGTTCCTGTGGGAACAGCCGATAAGGTTCGCGCGG
CTATTGCTGAACATGCAACCTGTGATTTTGATGTGGTTAGCAACCCAGAATTTTTGCGCGAAGGTGTTGCGGTTGATGAT
TTTCTTAAACCGGATCGTGTTGTTATCGGCAGTTCTTCCGAGAGAGCAACTGAAGTCATGCAGCAACTTTACGAACCGTT
TGTTCGCCAAGGCAACCCTATTTTGGTGATGGACGAACGCAGCGCTGAAATGACAAAATACGCGGCCAATTCCATGCTCG
CCCTTCGCATTTCATTTATGAATGAAATTGCAAATCTTTGCGATAAAGTTGGCGCAAATGTAGATATGGTTCGCCGCGGC
ATCGGGACCGATTTTCGTATTGGAAAGCATTTTCTCTATCCAGGCGTGGGCTACGGCGGAAGCTGCTTCCCAAAAGATGT
GAAAGCACTTATTAAAACGGCTCAAGATTATGAGTATAACTTCCAAATTTTGAAATCAGTCGAGTGCGTCAATGAAAGCC
AAAAGCATTTGTTAGTTCAAAAAATAGAAGCTTACTACGGCGGACGCGAACACATCGCGGGCAAAAAATTTGCCATGTGG
GGACTTTCCTTTAAACCAAACACCGACGATATTCGCGAAGCGCCATCGCTTGTCGTTATCCATGCGTTGCTTGAAATGGG
CGCTGAAATTGTCGCTTACGATCCAGAAGCAATGGGACATGTGAAGCAAATTGTTGGCGATAAAGTAACCTTCGCTTCTT
TAGCAGAGGATGCGCTGAACGACGCCGACGCGCTCATCATTGTCACAGAGTGGAATGAGTTCCGAAATCCTGATTTCAAT
TCAGTGAAGAAGCGCTTGAAACATCATCTCATTTTTGATGGCCGCAACGTTTTCGATAACCACAAAATGAAAGAATTAGG
CTTTGAATATTATAGCATTGGCCGCCCAACTTGCCAGCTATAA

Upstream 100 bases:

>100_bases
GAAATAGAGTAGGAATCCGCAGGTGTTACAAATGTGTGTGTTTTATTATTTCATTACCCCATAAGAAAATTCATCACCAT
CAATCAAAAAATCAAAAGAC

Downstream 100 bases:

>100_bases
TTTTATTAACCAACTTTCTACTGTTTTTTTCATGCTGCTGCTTGGCTCAAGCAAACGGCAGCAGCATGAAATTTTTCTGG
CAAAAAAAAAGCTGCTCACA

Product: nucleotide sugar dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKHVAVVGTGYVGLVAGTCFAETGNQVICVDIDKAKVEKLRNNVVTIYEPGLEVLFKRNLREKRLHFTTELAEAMESCDI
IFLALPTPPGEDGSADLKYVLGVAKEIGKLIKSYKVVVNKSTVPVGTADKVRAAIAEHATCDFDVVSNPEFLREGVAVDD
FLKPDRVVIGSSSERATEVMQQLYEPFVRQGNPILVMDERSAEMTKYAANSMLALRISFMNEIANLCDKVGANVDMVRRG
IGTDFRIGKHFLYPGVGYGGSCFPKDVKALIKTAQDYEYNFQILKSVECVNESQKHLLVQKIEAYYGGREHIAGKKFAMW
GLSFKPNTDDIREAPSLVVIHALLEMGAEIVAYDPEAMGHVKQIVGDKVTFASLAEDALNDADALIIVTEWNEFRNPDFN
SVKKRLKHHLIFDGRNVFDNHKMKELGFEYYSIGRPTCQL

Sequences:

>Translated_440_residues
MKHVAVVGTGYVGLVAGTCFAETGNQVICVDIDKAKVEKLRNNVVTIYEPGLEVLFKRNLREKRLHFTTELAEAMESCDI
IFLALPTPPGEDGSADLKYVLGVAKEIGKLIKSYKVVVNKSTVPVGTADKVRAAIAEHATCDFDVVSNPEFLREGVAVDD
FLKPDRVVIGSSSERATEVMQQLYEPFVRQGNPILVMDERSAEMTKYAANSMLALRISFMNEIANLCDKVGANVDMVRRG
IGTDFRIGKHFLYPGVGYGGSCFPKDVKALIKTAQDYEYNFQILKSVECVNESQKHLLVQKIEAYYGGREHIAGKKFAMW
GLSFKPNTDDIREAPSLVVIHALLEMGAEIVAYDPEAMGHVKQIVGDKVTFASLAEDALNDADALIIVTEWNEFRNPDFN
SVKKRLKHHLIFDGRNVFDNHKMKELGFEYYSIGRPTCQL
>Mature_440_residues
MKHVAVVGTGYVGLVAGTCFAETGNQVICVDIDKAKVEKLRNNVVTIYEPGLEVLFKRNLREKRLHFTTELAEAMESCDI
IFLALPTPPGEDGSADLKYVLGVAKEIGKLIKSYKVVVNKSTVPVGTADKVRAAIAEHATCDFDVVSNPEFLREGVAVDD
FLKPDRVVIGSSSERATEVMQQLYEPFVRQGNPILVMDERSAEMTKYAANSMLALRISFMNEIANLCDKVGANVDMVRRG
IGTDFRIGKHFLYPGVGYGGSCFPKDVKALIKTAQDYEYNFQILKSVECVNESQKHLLVQKIEAYYGGREHIAGKKFAMW
GLSFKPNTDDIREAPSLVVIHALLEMGAEIVAYDPEAMGHVKQIVGDKVTFASLAEDALNDADALIIVTEWNEFRNPDFN
SVKKRLKHHLIFDGRNVFDNHKMKELGFEYYSIGRPTCQL

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=466, Percent_Identity=33.6909871244635, Blast_Score=241, Evalue=9e-64,
Organism=Homo sapiens, GI296040438, Length=370, Percent_Identity=35.4054054054054, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI296040443, Length=459, Percent_Identity=29.8474945533769, Blast_Score=177, Evalue=2e-44,
Organism=Escherichia coli, GI1788340, Length=355, Percent_Identity=30.7042253521127, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI48994968, Length=435, Percent_Identity=28.0459770114943, Blast_Score=151, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17560350, Length=469, Percent_Identity=34.3283582089552, Blast_Score=245, Evalue=3e-65,
Organism=Drosophila melanogaster, GI17136908, Length=469, Percent_Identity=34.7547974413646, Blast_Score=259, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48970; Mature: 48970

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHVAVVGTGYVGLVAGTCFAETGNQVICVDIDKAKVEKLRNNVVTIYEPGLEVLFKRNL
CCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCEEEEECCCHHHHHHHCH
REKRLHFTTELAEAMESCDIIFLALPTPPGEDGSADLKYVLGVAKEIGKLIKSYKVVVNK
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEC
STVPVGTADKVRAAIAEHATCDFDVVSNPEFLREGVAVDDFLKPDRVVIGSSSERATEVM
CCCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHCCCCHHHCCCCCEEEECCCCHHHHHHH
QQLYEPFVRQGNPILVMDERSAEMTKYAANSMLALRISFMNEIANLCDKVGANVDMVRRG
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHC
IGTDFRIGKHFLYPGVGYGGSCFPKDVKALIKTAQDYEYNFQILKSVECVNESQKHLLVQ
CCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHH
KIEAYYGGREHIAGKKFAMWGLSFKPNTDDIREAPSLVVIHALLEMGAEIVAYDPEAMGH
HHHHHHCCHHHCCCCEEEEEECCCCCCCHHHHHCCHHHHHHHHHHCCCEEEEECCHHHHH
VKQIVGDKVTFASLAEDALNDADALIIVTEWNEFRNPDFNSVKKRLKHHLIFDGRNVFDN
HHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHEEECCCCCCCC
HKMKELGFEYYSIGRPTCQL
CHHHHHCCHHEECCCCCCCC
>Mature Secondary Structure
MKHVAVVGTGYVGLVAGTCFAETGNQVICVDIDKAKVEKLRNNVVTIYEPGLEVLFKRNL
CCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCEEEEECCCHHHHHHHCH
REKRLHFTTELAEAMESCDIIFLALPTPPGEDGSADLKYVLGVAKEIGKLIKSYKVVVNK
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEC
STVPVGTADKVRAAIAEHATCDFDVVSNPEFLREGVAVDDFLKPDRVVIGSSSERATEVM
CCCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHCCCCHHHCCCCCEEEECCCCHHHHHHH
QQLYEPFVRQGNPILVMDERSAEMTKYAANSMLALRISFMNEIANLCDKVGANVDMVRRG
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHC
IGTDFRIGKHFLYPGVGYGGSCFPKDVKALIKTAQDYEYNFQILKSVECVNESQKHLLVQ
CCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHH
KIEAYYGGREHIAGKKFAMWGLSFKPNTDDIREAPSLVVIHALLEMGAEIVAYDPEAMGH
HHHHHHCCHHHCCCCEEEEEECCCCCCCHHHHHCCHHHHHHHHHHCCCEEEEECCHHHHH
VKQIVGDKVTFASLAEDALNDADALIIVTEWNEFRNPDFNSVKKRLKHHLIFDGRNVFDN
HHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHEEECCCCCCCC
HKMKELGFEYYSIGRPTCQL
CHHHHHCCHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]