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The map label for this gene is cobT [H]

Identifier: 193213826

GI number: 193213826

Start: 125311

End: 126399

Strand: Direct

Name: cobT [H]

Synonym: Ctha_0107

Alternate gene names: 193213826

Gene position: 125311-126399 (Clockwise)

Preceding gene: 193213825

Following gene: 193213827

Centisome position: 3.8

GC content: 50.32

Gene sequence:

>1089_bases
ATGCAAAAAGAAGTTTTTTCCGATTTGCTCAAACAAGCCCAACACAAGCTTGACCGCAAAACCAAGCCCGTTGGTTCGCT
TGGTAAACTTGAAACATTAGCCGCGCAACTTGCAGCCATTCAAGGTTCGCTCGAACCAAACATCGATAAAAAGCGAATGC
TCATATTCGCAGCAAGTCATGGCATTGCAGCCGAAGGCGTCAGCGCGTATCCACCGGAAGTAACCGGACAAATGGTGCTC
AATTTCCTCAACGGCGGAGCGGCGATTAATGTGCTTTCGCGCCACGGCAAAATGAATTTACATGTGATTGATGTTGGCGT
GGATGTCGATTTATCGGACTCAGCAAAAGAGGCGTCGAACTTCTTTTCGCGCCGTGTAACAAATGGCACCAAAAGCTTCC
TCCGTGAGCCTGCCATGACAGCAGAAGAATGCGAAGCTGCGCTGAAAGCTGGTTACGAGCAAGTTCAGCTCGCGCACGAG
CAGCAAGTTCGTTTATTAGGCATTGGTGAAATGGGCATTGGAAACACGACTGCCGCTGCCGCGCTTTTTTCCGCGCTGCT
AAATATTCATCCAGAGGAAATTGTAGGACCAGGAACCGGCCTGAATGAAGCAGGCGTTCGCCACAAAGCGTTGGTGATTC
AAAAGGCTTTAGATTTGCATCGCGAAAAATCTGGCGCTGATCCGGTTGCTTGGCTTCAGCATGTCGGCGGACTTGAAATC
GCTGCGATGACAGGCGTTATTTTGGAAGCTTACCGCTTGCAGATGCCCGTGGTCGTCGACGGGTTTATTGCCACATCTGC
AGCGATGGTTGCCTTACAAATCGAGCCAGCGGCAAAACAAATTTGTTTCTTTGGCCATCGTTCCAATGAAAAAGCGCACC
GTCTTGTACTCGAAAAACTCGATGCCAATCCGGTTTTAGATTTGGAAATGCGATTGGGCGAAGGCACCGGCGCGGCGCTG
GCCATGCACCTTTTGGATGCCGCTGCAAAAATCATGTGCGAAATGGCTACCTTCGACACCGCAGGCGTTTCCGATTCCGA
GCAAGATGCGAACAAACAAGCTCGCTCGGCTTCCGAAAAAAACGATTAA

Upstream 100 bases:

>100_bases
CTACAATCCAATTAACCGACGAAGCGGTATTTTTTCAACGAACAAAGTAAACGCACGTAGCAAGCATAACTGAGCTTGCA
ACCATAAAAATGACTCTGCG

Downstream 100 bases:

>100_bases
CCCGCTACTGTGAAAACCCAATTCAATGTTTTTTTGTCCGCTGTTATGTTTCTCACCCGTCTGCCGGTTGGCAGATGGGT
GCACTACAATGCTGAGCATC

Product: nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MQKEVFSDLLKQAQHKLDRKTKPVGSLGKLETLAAQLAAIQGSLEPNIDKKRMLIFAASHGIAAEGVSAYPPEVTGQMVL
NFLNGGAAINVLSRHGKMNLHVIDVGVDVDLSDSAKEASNFFSRRVTNGTKSFLREPAMTAEECEAALKAGYEQVQLAHE
QQVRLLGIGEMGIGNTTAAAALFSALLNIHPEEIVGPGTGLNEAGVRHKALVIQKALDLHREKSGADPVAWLQHVGGLEI
AAMTGVILEAYRLQMPVVVDGFIATSAAMVALQIEPAAKQICFFGHRSNEKAHRLVLEKLDANPVLDLEMRLGEGTGAAL
AMHLLDAAAKIMCEMATFDTAGVSDSEQDANKQARSASEKND

Sequences:

>Translated_362_residues
MQKEVFSDLLKQAQHKLDRKTKPVGSLGKLETLAAQLAAIQGSLEPNIDKKRMLIFAASHGIAAEGVSAYPPEVTGQMVL
NFLNGGAAINVLSRHGKMNLHVIDVGVDVDLSDSAKEASNFFSRRVTNGTKSFLREPAMTAEECEAALKAGYEQVQLAHE
QQVRLLGIGEMGIGNTTAAAALFSALLNIHPEEIVGPGTGLNEAGVRHKALVIQKALDLHREKSGADPVAWLQHVGGLEI
AAMTGVILEAYRLQMPVVVDGFIATSAAMVALQIEPAAKQICFFGHRSNEKAHRLVLEKLDANPVLDLEMRLGEGTGAAL
AMHLLDAAAKIMCEMATFDTAGVSDSEQDANKQARSASEKND
>Mature_362_residues
MQKEVFSDLLKQAQHKLDRKTKPVGSLGKLETLAAQLAAIQGSLEPNIDKKRMLIFAASHGIAAEGVSAYPPEVTGQMVL
NFLNGGAAINVLSRHGKMNLHVIDVGVDVDLSDSAKEASNFFSRRVTNGTKSFLREPAMTAEECEAALKAGYEQVQLAHE
QQVRLLGIGEMGIGNTTAAAALFSALLNIHPEEIVGPGTGLNEAGVRHKALVIQKALDLHREKSGADPVAWLQHVGGLEI
AAMTGVILEAYRLQMPVVVDGFIATSAAMVALQIEPAAKQICFFGHRSNEKAHRLVLEKLDANPVLDLEMRLGEGTGAAL
AMHLLDAAAKIMCEMATFDTAGVSDSEQDANKQARSASEKND

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=350, Percent_Identity=37.7142857142857, Blast_Score=212, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 38644; Mature: 38644

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKEVFSDLLKQAQHKLDRKTKPVGSLGKLETLAAQLAAIQGSLEPNIDKKRMLIFAASH
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECC
GIAAEGVSAYPPEVTGQMVLNFLNGGAAINVLSRHGKMNLHVIDVGVDVDLSDSAKEASN
CCCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHCCCEEEEEEEEEECCCCCCHHHHHHH
FFSRRVTNGTKSFLREPAMTAEECEAALKAGYEQVQLAHEQQVRLLGIGEMGIGNTTAAA
HHHHHHCCHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCEEEEEECCCCCCCHHHHH
ALFSALLNIHPEEIVGPGTGLNEAGVRHKALVIQKALDLHREKSGADPVAWLQHVGGLEI
HHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHH
AAMTGVILEAYRLQMPVVVDGFIATSAAMVALQIEPAAKQICFFGHRSNEKAHRLVLEKL
HHHHHHHHHHHHHCCCCEEHHHHHHHHEEEEEEECHHHHHHEEECCCCCCHHHHHHHHHC
DANPVLDLEMRLGEGTGAALAMHLLDAAAKIMCEMATFDTAGVSDSEQDANKQARSASEK
CCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCC
ND
CC
>Mature Secondary Structure
MQKEVFSDLLKQAQHKLDRKTKPVGSLGKLETLAAQLAAIQGSLEPNIDKKRMLIFAASH
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECC
GIAAEGVSAYPPEVTGQMVLNFLNGGAAINVLSRHGKMNLHVIDVGVDVDLSDSAKEASN
CCCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHCCCEEEEEEEEEECCCCCCHHHHHHH
FFSRRVTNGTKSFLREPAMTAEECEAALKAGYEQVQLAHEQQVRLLGIGEMGIGNTTAAA
HHHHHHCCHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCEEEEEECCCCCCCHHHHH
ALFSALLNIHPEEIVGPGTGLNEAGVRHKALVIQKALDLHREKSGADPVAWLQHVGGLEI
HHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHH
AAMTGVILEAYRLQMPVVVDGFIATSAAMVALQIEPAAKQICFFGHRSNEKAHRLVLEKL
HHHHHHHHHHHHHCCCCEEHHHHHHHHEEEEEEECHHHHHHEEECCCCCCHHHHHHHHHC
DANPVLDLEMRLGEGTGAALAMHLLDAAAKIMCEMATFDTAGVSDSEQDANKQARSASEK
CCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCC
ND
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA