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The map label for this gene is fruA [H]

Identifier: 193213733

GI number: 193213733

Start: 17017

End: 17526

Strand: Direct

Name: fruA [H]

Synonym: Ctha_0013

Alternate gene names: 193213733

Gene position: 17017-17526 (Clockwise)

Preceding gene: 193213732

Following gene: 193213734

Centisome position: 0.52

GC content: 38.43

Gene sequence:

>510_bases
ATGAGCGTAAACTTCTTGAACTTTAACTTGCATTTTACAATGAAGCTCTCAGACCTTTTGTCCAAAGAATATATTTTACT
TGGGCTGGATATTAATACAAAAGAAGGCGTCATTGAAAAAATGCTCTCTCTTGTTTCTAATCATCCCAATTTGGTGGATA
ATGAAAAATTAAGAGAAGATGTGTTGAAACGCGAAGAAGAAATGTCTACCGGAATTGGCAAAAATATTGCGTTGCCCCAT
GCAAAAACAGAAGCAGTTACTCAGCCAATTTTAGCATTTGCTTTGCTTAAAAAAGCCGTTGAATTTGACGCGATTGACAG
CCAACCCGTTCGATTTGTGTTTTTGCTTGCAACACCGGAACAGATGCTTGCCCAACACTTGAAGTTGCTGAGCAGAATTT
CCAGAGTTGCTAGCAAAGAAGAAATCCGAAATAGACTTTTGGAGACCAAAGACCCAGCTTCTGTGCTTTCTGTCTTTATT
GAAGAAGAAAAAGCCTTCCCTGAAATTTAG

Upstream 100 bases:

>100_bases
TACAGATTTAAAATCGCTCAGAAAATGCAAAAGGGTTTCGTATATTTCGCCCCTTGTTTTGTCACTACAGGACGATAATT
AGCAGGCTTGACCAGCCGCC

Downstream 100 bases:

>100_bases
TTGTTAAAAAAGTCCAGTATGAAGTTTCAGACCATCAAAGGGACCAAAGACATCCTACCTTCAGAAATTCACAAATGGCA
TTACGTAGAAAACACTGTTC

Product: putative PTS IIA-like nitrogen-regulatory protein PtsN

Products: NA

Alternate protein names: EIIABC-Fru; Fructose-specific phosphotransferase enzyme IIA component; EII-Fru; PTS system fructose-specific EIIA component; Fructose-specific phosphotransferase enzyme IIB component; EIII-Fru; PTS system fructose-specific EIIB component; Fructose permease IIC component; PTS system fructose-specific EIIC component [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MSVNFLNFNLHFTMKLSDLLSKEYILLGLDINTKEGVIEKMLSLVSNHPNLVDNEKLREDVLKREEEMSTGIGKNIALPH
AKTEAVTQPILAFALLKKAVEFDAIDSQPVRFVFLLATPEQMLAQHLKLLSRISRVASKEEIRNRLLETKDPASVLSVFI
EEEKAFPEI

Sequences:

>Translated_169_residues
MSVNFLNFNLHFTMKLSDLLSKEYILLGLDINTKEGVIEKMLSLVSNHPNLVDNEKLREDVLKREEEMSTGIGKNIALPH
AKTEAVTQPILAFALLKKAVEFDAIDSQPVRFVFLLATPEQMLAQHLKLLSRISRVASKEEIRNRLLETKDPASVLSVFI
EEEKAFPEI
>Mature_168_residues
SVNFLNFNLHFTMKLSDLLSKEYILLGLDINTKEGVIEKMLSLVSNHPNLVDNEKLREDVLKREEEMSTGIGKNIALPHA
KTEAVTQPILAFALLKKAVEFDAIDSQPVRFVFLLATPEQMLAQHLKLLSRISRVASKEEIRNRLLETKDPASVLSVFIE
EEKAFPEI

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1762

COG function: function code GT; Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1786951, Length=158, Percent_Identity=25.9493670886076, Blast_Score=71, Evalue=4e-14,
Organism=Escherichia coli, GI1789597, Length=139, Percent_Identity=33.0935251798561, Blast_Score=67, Evalue=5e-13,
Organism=Escherichia coli, GI48994992, Length=163, Percent_Identity=27.6073619631902, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 19158; Mature: 19026

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNFLNFNLHFTMKLSDLLSKEYILLGLDINTKEGVIEKMLSLVSNHPNLVDNEKLRED
CCCEEEEEEEEEEEEHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
VLKREEEMSTGIGKNIALPHAKTEAVTQPILAFALLKKAVEFDAIDSQPVRFVFLLATPE
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECHH
QMLAQHLKLLSRISRVASKEEIRNRLLETKDPASVLSVFIEEEKAFPEI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SVNFLNFNLHFTMKLSDLLSKEYILLGLDINTKEGVIEKMLSLVSNHPNLVDNEKLRED
CCEEEEEEEEEEEEHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
VLKREEEMSTGIGKNIALPHAKTEAVTQPILAFALLKKAVEFDAIDSQPVRFVFLLATPE
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECHH
QMLAQHLKLLSRISRVASKEEIRNRLLETKDPASVLSVFIEEEKAFPEI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]