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The map label for this gene is siaT [H]

Identifier: 192291496

GI number: 192291496

Start: 3364659

End: 3366542

Strand: Reverse

Name: siaT [H]

Synonym: Rpal_3120

Alternate gene names: 192291496

Gene position: 3366542-3364659 (Counterclockwise)

Preceding gene: 192291497

Following gene: 192291495

Centisome position: 58.61

GC content: 67.41

Gene sequence:

>1884_bases
ATGGCGAGCGCCGACGCTTCCCAGCTCACAGCCGGTGAACGGCTCCACGCGCCGCAGCGTAAAACGCTGATCGGCGCGCT
GGAGGCTGCGCTCGGCCTGATGGTCGAGATTCCGGCGGCGATCCTGGTGGTCGTCGAGATTGTCGTGCTGTTCGCCGGCG
TGGTATCTCGCTACGTCTTCCACAGCCCGCTGATCTGGTCCGACGAACTGGCGTCGATCCTGTTTCTGTGGCTGGCGATG
TTCGGCGCGGCGGTCGCGTTCCGCCGCGGCGAGCACATGCGGATGACCGCGATGGTGGCCGGGGCCTCCCCGCGCCTGCG
CGCCTGGCTCGATCTGGTCGGCATCTGTGCGGCGCTGGCGTTCCTGCTGCTGATCGCGGCACCGGCCTACGAATACGCCT
ACGAGGAAAGCTACATCACCACGCCGGCTCTCTCGATCGCCAACAGCTGGCGCGCCGCGGCGCTGCCGGTCGGCATTGCG
CTGATGGCGCTGTTCGCAGCTCTGCGGCTGATCCGGTTCGGCGATCTCAAGCTGGTCGTTGGCGCTGCGCTGACGGTCGC
GCTGCTGATCGGCGCGTTCTGGCTGGCGCAGCCGCTGTTCAAGCCGCTCGGCAACATCAATCTGGTGATCTTCTTCGTCG
GCGTGGTGGCTTGTTGCGTGTTCGCCGGCGTGCCAATCGCGTTCGGATTTGGCCTCGCGATCTACGGTTATCTGGCGCTG
ACGACGACGACGCCGCTCTTGATCCTGGTCGGCCGGATGGACGAGGGCATGAGCCACCTCATCCTGCTGTCGGTGCCGCT
GTTCGTCTTCCTCGGCCTGTTGATCGAGATGACCGGGATGGCGCGGGCGATGGTGGCGTTTCTCGCCAGCCTGCTCGGCC
ACGTCCGCGGCGGCCTGCACTACGTGCTGGTCGGCGCAATGTACCTGGTGTCCGGCATCTCCGGCTCGAAGGCCGCCGAC
ATGGCCGCGGTCGCGCCGGTGCTGTTTCCGGAGATGAAGGAGCGCGGGGCCAAGCCCGGCGATCTGGTCGCCCTGCTCTC
CGCCACCGGCGCCCAGACCGAAACCATTCCGCCGAGCTTGGTGCTGATCACCATCGGCTCGGTCACCGGCGTGTCGATCT
CGGCGCTGTTCACCGGCGGCCTGCTGCCCGGCGTGGTGCTGGCGATCATGCTGAGCGCCCTGGTGTGGTGGCGCTATCGC
GGCGAGGATCTCAGCCACGTCAAGCGCGCACGCGGCAGCGAGATCGGCAAGGCGTTCATCGTCGCCCTGCCCGCGCTGGC
GCTGCCGTTCGTGATCCGCGCCGCCGTGGTCGAAGGCGTCGCCACCGCCACCGAAGTTTCGACCATCGGCATCGTCTATG
CCGTGGTGGTCGGCATCCTGGTGTACCGCAAGTTCGACTTGCGCCGGCTGCGGCCGATGCTGGTCGAGACCGCGGCGCTG
TCGGGTGCGATCCTGTTGATCATCGGCACCGCGACCGGCATGGCCTGGGGCCTGACGCAGTCCGGCTTCTCGCGGGCGCT
GGCGGCGGCGATGACCGGCCTGCCCGGTGGCTCCGCCACCTTCCTGGCGGTGTCGATCGTCGCCTTCGTCATCCTCGGCA
GCGTGCTGGAGGGCATTCCGGCGATCGTGCTATTCGGGCCGCTGTTGTTTCCGATCGCCCGCGCCGTCGGCATCCACGAG
GTGCACTACGCCATGGTGGTGATCCTGGCGATGGGCATCGGATTGTTCGCGCCGCCGTTCGGCGTCGGCTATTATGCAGC
CTGCGCGATTGGCCGGGTCGATCCCGCCGAAGGCATGCGCCCGATCTGGGGATATATGCTGGCGCTACTGATCGGCTTGA
TCGTCGTCGCGGCGATCCCGTGGATCTCGATTGGATTCTTGTAG

Upstream 100 bases:

>100_bases
CAGCGCCGGCTTCTATGCCGAGTGGAAAGGCAAATACGGCGATCAGGCGTGGTCGCTGCTCGAGAAGTCAGTCGGCAAGC
TGGCGTAACGGCTGGCCGAC

Downstream 100 bases:

>100_bases
AGGCGCTGCGGGGAGATTGCAGCGGCGCCGTCGTGAAGTGAGAGGCAGATCGTCATGAGCACCCCGCAAGGTCACTACAG
CATCGGTCTGGACAAGACCC

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 627; Mature: 626

Protein sequence:

>627_residues
MASADASQLTAGERLHAPQRKTLIGALEAALGLMVEIPAAILVVVEIVVLFAGVVSRYVFHSPLIWSDELASILFLWLAM
FGAAVAFRRGEHMRMTAMVAGASPRLRAWLDLVGICAALAFLLLIAAPAYEYAYEESYITTPALSIANSWRAAALPVGIA
LMALFAALRLIRFGDLKLVVGAALTVALLIGAFWLAQPLFKPLGNINLVIFFVGVVACCVFAGVPIAFGFGLAIYGYLAL
TTTTPLLILVGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVAFLASLLGHVRGGLHYVLVGAMYLVSGISGSKAAD
MAAVAPVLFPEMKERGAKPGDLVALLSATGAQTETIPPSLVLITIGSVTGVSISALFTGGLLPGVVLAIMLSALVWWRYR
GEDLSHVKRARGSEIGKAFIVALPALALPFVIRAAVVEGVATATEVSTIGIVYAVVVGILVYRKFDLRRLRPMLVETAAL
SGAILLIIGTATGMAWGLTQSGFSRALAAAMTGLPGGSATFLAVSIVAFVILGSVLEGIPAIVLFGPLLFPIARAVGIHE
VHYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPAEGMRPIWGYMLALLIGLIVVAAIPWISIGFL

Sequences:

>Translated_627_residues
MASADASQLTAGERLHAPQRKTLIGALEAALGLMVEIPAAILVVVEIVVLFAGVVSRYVFHSPLIWSDELASILFLWLAM
FGAAVAFRRGEHMRMTAMVAGASPRLRAWLDLVGICAALAFLLLIAAPAYEYAYEESYITTPALSIANSWRAAALPVGIA
LMALFAALRLIRFGDLKLVVGAALTVALLIGAFWLAQPLFKPLGNINLVIFFVGVVACCVFAGVPIAFGFGLAIYGYLAL
TTTTPLLILVGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVAFLASLLGHVRGGLHYVLVGAMYLVSGISGSKAAD
MAAVAPVLFPEMKERGAKPGDLVALLSATGAQTETIPPSLVLITIGSVTGVSISALFTGGLLPGVVLAIMLSALVWWRYR
GEDLSHVKRARGSEIGKAFIVALPALALPFVIRAAVVEGVATATEVSTIGIVYAVVVGILVYRKFDLRRLRPMLVETAAL
SGAILLIIGTATGMAWGLTQSGFSRALAAAMTGLPGGSATFLAVSIVAFVILGSVLEGIPAIVLFGPLLFPIARAVGIHE
VHYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPAEGMRPIWGYMLALLIGLIVVAAIPWISIGFL
>Mature_626_residues
ASADASQLTAGERLHAPQRKTLIGALEAALGLMVEIPAAILVVVEIVVLFAGVVSRYVFHSPLIWSDELASILFLWLAMF
GAAVAFRRGEHMRMTAMVAGASPRLRAWLDLVGICAALAFLLLIAAPAYEYAYEESYITTPALSIANSWRAAALPVGIAL
MALFAALRLIRFGDLKLVVGAALTVALLIGAFWLAQPLFKPLGNINLVIFFVGVVACCVFAGVPIAFGFGLAIYGYLALT
TTTPLLILVGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVAFLASLLGHVRGGLHYVLVGAMYLVSGISGSKAADM
AAVAPVLFPEMKERGAKPGDLVALLSATGAQTETIPPSLVLITIGSVTGVSISALFTGGLLPGVVLAIMLSALVWWRYRG
EDLSHVKRARGSEIGKAFIVALPALALPFVIRAAVVEGVATATEVSTIGIVYAVVVGILVYRKFDLRRLRPMLVETAALS
GAILLIIGTATGMAWGLTQSGFSRALAAAMTGLPGGSATFLAVSIVAFVILGSVLEGIPAIVLFGPLLFPIARAVGIHEV
HYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPAEGMRPIWGYMLALLIGLIVVAAIPWISIGFL

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=392, Percent_Identity=27.2959183673469, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 65734; Mature: 65603

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASADASQLTAGERLHAPQRKTLIGALEAALGLMVEIPAAILVVVEIVVLFAGVVSRYVF
CCCCCCHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSPLIWSDELASILFLWLAMFGAAVAFRRGEHMRMTAMVAGASPRLRAWLDLVGICAALA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
FLLLIAAPAYEYAYEESYITTPALSIANSWRAAALPVGIALMALFAALRLIRFGDLKLVV
HHHHHHCCHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GAALTVALLIGAFWLAQPLFKPLGNINLVIFFVGVVACCVFAGVPIAFGFGLAIYGYLAL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TTTTPLLILVGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVAFLASLLGHVRGGLH
HHCCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YVLVGAMYLVSGISGSKAADMAAVAPVLFPEMKERGAKPGDLVALLSATGAQTETIPPSL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCE
VLITIGSVTGVSISALFTGGLLPGVVLAIMLSALVWWRYRGEDLSHVKRARGSEIGKAFI
EEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHH
VALPALALPFVIRAAVVEGVATATEVSTIGIVYAVVVGILVYRKFDLRRLRPMLVETAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGAILLIIGTATGMAWGLTQSGFSRALAAAMTGLPGGSATFLAVSIVAFVILGSVLEGIP
CCEEEEEEECCCCHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AIVLFGPLLFPIARAVGIHEVHYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPAEGMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHCCCC
PIWGYMLALLIGLIVVAAIPWISIGFL
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASADASQLTAGERLHAPQRKTLIGALEAALGLMVEIPAAILVVVEIVVLFAGVVSRYVF
CCCCCHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSPLIWSDELASILFLWLAMFGAAVAFRRGEHMRMTAMVAGASPRLRAWLDLVGICAALA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
FLLLIAAPAYEYAYEESYITTPALSIANSWRAAALPVGIALMALFAALRLIRFGDLKLVV
HHHHHHCCHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GAALTVALLIGAFWLAQPLFKPLGNINLVIFFVGVVACCVFAGVPIAFGFGLAIYGYLAL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TTTTPLLILVGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVAFLASLLGHVRGGLH
HHCCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YVLVGAMYLVSGISGSKAADMAAVAPVLFPEMKERGAKPGDLVALLSATGAQTETIPPSL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCE
VLITIGSVTGVSISALFTGGLLPGVVLAIMLSALVWWRYRGEDLSHVKRARGSEIGKAFI
EEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHH
VALPALALPFVIRAAVVEGVATATEVSTIGIVYAVVVGILVYRKFDLRRLRPMLVETAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGAILLIIGTATGMAWGLTQSGFSRALAAAMTGLPGGSATFLAVSIVAFVILGSVLEGIP
CCEEEEEEECCCCHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AIVLFGPLLFPIARAVGIHEVHYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPAEGMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHCCCC
PIWGYMLALLIGLIVVAAIPWISIGFL
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]