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The map label for this gene is dgdR [H]

Identifier: 192291329

GI number: 192291329

Start: 3224676

End: 3225590

Strand: Reverse

Name: dgdR [H]

Synonym: Rpal_2951

Alternate gene names: 192291329

Gene position: 3225590-3224676 (Counterclockwise)

Preceding gene: 192291334

Following gene: 192291328

Centisome position: 56.16

GC content: 65.25

Gene sequence:

>915_bases
ATGCTCGCCCCACTCGACCTCCGCCTGCTGCAGACCTTCATCGTGCTGGTTCAGACCGGCAGCTTCTCCGAAACGTCGCG
GCGGCTGGGCCGGACCCAGCCGGCCGTCAGCCTGCAGCTCAACCGGCTCGAGGAAGCAACCGGGGCACCGCTGTTCACCA
AGGTCGGCCGCAAGCTGGTGCTGACTAATCATGGTGAGCTCGTACTCGGCTATGCGCGTACCATCATGGGCCTGCAGGAC
GAACTACGCGCCCGCCTCGCCGCACCGAAGCTCGACGGCGTGGTCGTGCTCGGGATGCCCGATCTCTACGCCGCCTATCT
GCTGCCCGGCATCCTGGCGGACTTCCGCAGCGCTTACCCCAATGTCGATGTCGAGCTGAAATGCGCGCTGTCGAGCAAGT
TGATGGCTTCGGTCGAACGCGCGGAGATCGATCTGGCGATCGTCACAGGCATGCCCGCGTTCAAGGTCGGGGAGTTGGTG
GCGCAAGAGGAACTGGTGTGGGTCGCCTCAGAGCGAAGCTCAGTGCACCTCGAAAACCCCGTGCCGCTGGCGATGCTGCC
GCCCGGCAACATCTTCCGCGATTTCGGTCTCGCGGCGCTCGAGAGCATCGGCCGGATCTGGCGGCTGAGCTGCATCAGCG
AGAGCATCAGCGGCATTCAGGCGGCGGTGTTCTCAGGGATCGCGGTCAGCGTCGTCGGCAAAAGCTCGGTGCTGCCGGGG
ATGCGCATACTCGGACGCGGTGACACCTTCCCCGCATTGCCCAAGGTCGATCTGGTGTTGTACCGCTCGGCCCGTAGCTC
CAATCCCGCAGCAGAGGCCCTCGCCAGCGTGATCGTGCGGCACTTCGCGAATTCAGCGCTCGCTCCAGCGGCGCGTTTCG
TGCGAACCCAGGCTGGCAGCGGATCGCACGAGTAA

Upstream 100 bases:

>100_bases
GCTTCCTCGCTGCTGATCCCGGCAAGCCACTGTAGGTGCGACGCAACAACATCAGAAATTTATTGTTTATATCGGTTTTA
TAAGCTGGCTTAATAGAACG

Downstream 100 bases:

>100_bases
CAATATCGCTGCCGATCAGGGCAGCCGCAGATGCGGGGCGGCGATCACGATCGCTCCGATCAGACCGAACGCTGCACCGA
GCATCAGGACGTGAATATCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MLAPLDLRLLQTFIVLVQTGSFSETSRRLGRTQPAVSLQLNRLEEATGAPLFTKVGRKLVLTNHGELVLGYARTIMGLQD
ELRARLAAPKLDGVVVLGMPDLYAAYLLPGILADFRSAYPNVDVELKCALSSKLMASVERAEIDLAIVTGMPAFKVGELV
AQEELVWVASERSSVHLENPVPLAMLPPGNIFRDFGLAALESIGRIWRLSCISESISGIQAAVFSGIAVSVVGKSSVLPG
MRILGRGDTFPALPKVDLVLYRSARSSNPAAEALASVIVRHFANSALAPAARFVRTQAGSGSHE

Sequences:

>Translated_304_residues
MLAPLDLRLLQTFIVLVQTGSFSETSRRLGRTQPAVSLQLNRLEEATGAPLFTKVGRKLVLTNHGELVLGYARTIMGLQD
ELRARLAAPKLDGVVVLGMPDLYAAYLLPGILADFRSAYPNVDVELKCALSSKLMASVERAEIDLAIVTGMPAFKVGELV
AQEELVWVASERSSVHLENPVPLAMLPPGNIFRDFGLAALESIGRIWRLSCISESISGIQAAVFSGIAVSVVGKSSVLPG
MRILGRGDTFPALPKVDLVLYRSARSSNPAAEALASVIVRHFANSALAPAARFVRTQAGSGSHE
>Mature_304_residues
MLAPLDLRLLQTFIVLVQTGSFSETSRRLGRTQPAVSLQLNRLEEATGAPLFTKVGRKLVLTNHGELVLGYARTIMGLQD
ELRARLAAPKLDGVVVLGMPDLYAAYLLPGILADFRSAYPNVDVELKCALSSKLMASVERAEIDLAIVTGMPAFKVGELV
AQEELVWVASERSSVHLENPVPLAMLPPGNIFRDFGLAALESIGRIWRLSCISESISGIQAAVFSGIAVSVVGKSSVLPG
MRILGRGDTFPALPKVDLVLYRSARSSNPAAEALASVIVRHFANSALAPAARFVRTQAGSGSHE

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=271, Percent_Identity=32.4723247232472, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788481, Length=281, Percent_Identity=24.5551601423488, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI157672245, Length=142, Percent_Identity=30.9859154929577, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787806, Length=146, Percent_Identity=27.3972602739726, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=32.4137931034483, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788748, Length=300, Percent_Identity=27, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788887, Length=147, Percent_Identity=29.9319727891156, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693105, Length=144, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082132, Length=249, Percent_Identity=27.3092369477912, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787601, Length=154, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1790399, Length=248, Percent_Identity=22.9838709677419, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32511; Mature: 32511

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAPLDLRLLQTFIVLVQTGSFSETSRRLGRTQPAVSLQLNRLEEATGAPLFTKVGRKLV
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHCCCEEE
LTNHGELVLGYARTIMGLQDELRARLAAPKLDGVVVLGMPDLYAAYLLPGILADFRSAYP
EECCCCEEEHHHHHHHCHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCC
NVDVELKCALSSKLMASVERAEIDLAIVTGMPAFKVGELVAQEELVWVASERSSVHLENP
CCCEEEEEHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHEEEEECCCCEEEECCC
VPLAMLPPGNIFRDFGLAALESIGRIWRLSCISESISGIQAAVFSGIAVSVVGKSSVLPG
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCC
MRILGRGDTFPALPKVDLVLYRSARSSNPAAEALASVIVRHFANSALAPAARFVRTQAGS
HHEEECCCCCCCCCCHHHEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
GSHE
CCCC
>Mature Secondary Structure
MLAPLDLRLLQTFIVLVQTGSFSETSRRLGRTQPAVSLQLNRLEEATGAPLFTKVGRKLV
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHCCCEEE
LTNHGELVLGYARTIMGLQDELRARLAAPKLDGVVVLGMPDLYAAYLLPGILADFRSAYP
EECCCCEEEHHHHHHHCHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCC
NVDVELKCALSSKLMASVERAEIDLAIVTGMPAFKVGELVAQEELVWVASERSSVHLENP
CCCEEEEEHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHEEEEECCCCEEEECCC
VPLAMLPPGNIFRDFGLAALESIGRIWRLSCISESISGIQAAVFSGIAVSVVGKSSVLPG
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCC
MRILGRGDTFPALPKVDLVLYRSARSSNPAAEALASVIVRHFANSALAPAARFVRTQAGS
HHEEECCCCCCCCCCHHHEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
GSHE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]