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The map label for this gene is pdtaS [H]

Identifier: 192291089

GI number: 192291089

Start: 2942093

End: 2943184

Strand: Reverse

Name: pdtaS [H]

Synonym: Rpal_2710

Alternate gene names: 192291089

Gene position: 2943184-2942093 (Counterclockwise)

Preceding gene: 192291090

Following gene: 192291088

Centisome position: 51.24

GC content: 66.76

Gene sequence:

>1092_bases
ATGACAGACGCCAAGCCGACCCTGCTCTACATCGACGACGACGAGGCGCTCGGCCGCCTCGTGTCGCGCGGCCTGCAGCG
GCAGGGATTCTGCGTCGAACACGTGCTGAGCGGCGAAGCCGGCCTGGAGCGGTTGCGCCAGGGCGGCATCGACGTGATCG
CGCTCGACCAGTACATGCCCGGCCTCGACGGGCTGGAGACGCTGGAGCAGATCCAGGCGATCCCGGATCCGCCGCCGGTG
GTGTTCGTCACCGCCTCGCAAGATTCAAAGATCGCCGTCACCGCGCTGAAAGCCGGTGCCGACGATTATCTGGTCAAGGA
CACGCAGGGCGAGTTCGTGCCGCTGCTGCAGGTCGCTGCCGATCAGGCGTTGAAGCAGGCGATGGTGCGCAAGGCGCGCG
ACGACGCCGAAGCCGAAGTGCGTGCCTCGCGCGACCGCTATGCCGCGCTCGCCGCCGAGCGCGAAATGCTGCTCCGTGAG
GTTAACCACCGCGTCGGCAATTCGCTGCAGATCATCGCCTCACTGCTGCATCTGCAGGCGTCGTCCAGCAAGCAGGACGA
GGTCAAGGCGGCGCTGACCAATGCGATGGGCCGCGTCGCCGCGGTGGCGCAGGTACACCGCCGACTCTACACCTCGCACG
ACCTCAAGAGCGTGATGCTCAACCAGTATCTCGAGTCGCTGCTCGAAGATCTGAGGCGCTCGGCCGAGGGCAACCGGATG
TCGCGCCTGACGCTGTCGGCGCAGCCGGTCGAAACCGATCCGGACCGCGCCGTGGCGATCGGCATCATCGTCAACGAACT
GGTGATGAACGCTGTCAAATACGCCTATCCGGAGGGCAAGGGGCCGATCCACGTCGAGCTGAAGGCCGACGGCGACGACC
TCGAACTGGTGATCGCCGACGAAGGCGTCGGCCTGAACGTCAAGGCCAATCCGCAATCGACCGGCATGGGCCAGCGCATT
GTCAGCGCGATGGCGGCCAAGCTCGAAGCCGATGTCGAGCGCGACCCCAACCATTCAGGCACCCGCATGGTGCTGCGGTT
TCGCCGTGCCAACGCGACCGCCGCAGCGGCGCCGGAGCCGGCGACTCCCTGA

Upstream 100 bases:

>100_bases
TCTACATCACCAAGCCGGTGAACTACGAAAGCTTCGCCAACGCGATCCGCCAACTCGGCCTGTTCTTTTCGGTCATCCAG
GTCCCCCAGCCCGACGCTCC

Downstream 100 bases:

>100_bases
TCTGGTCCTGCTCCGCCGCAGGGTGACACCGGCCCGCCTGCGCACTACACAAGCCGCGGGTTCTCCGGCCGGACGAACCG
CCGGTCCTCACCTTTTCTGC

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTDAKPTLLYIDDDEALGRLVSRGLQRQGFCVEHVLSGEAGLERLRQGGIDVIALDQYMPGLDGLETLEQIQAIPDPPPV
VFVTASQDSKIAVTALKAGADDYLVKDTQGEFVPLLQVAADQALKQAMVRKARDDAEAEVRASRDRYAALAAEREMLLRE
VNHRVGNSLQIIASLLHLQASSSKQDEVKAALTNAMGRVAAVAQVHRRLYTSHDLKSVMLNQYLESLLEDLRRSAEGNRM
SRLTLSAQPVETDPDRAVAIGIIVNELVMNAVKYAYPEGKGPIHVELKADGDDLELVIADEGVGLNVKANPQSTGMGQRI
VSAMAAKLEADVERDPNHSGTRMVLRFRRANATAAAAPEPATP

Sequences:

>Translated_363_residues
MTDAKPTLLYIDDDEALGRLVSRGLQRQGFCVEHVLSGEAGLERLRQGGIDVIALDQYMPGLDGLETLEQIQAIPDPPPV
VFVTASQDSKIAVTALKAGADDYLVKDTQGEFVPLLQVAADQALKQAMVRKARDDAEAEVRASRDRYAALAAEREMLLRE
VNHRVGNSLQIIASLLHLQASSSKQDEVKAALTNAMGRVAAVAQVHRRLYTSHDLKSVMLNQYLESLLEDLRRSAEGNRM
SRLTLSAQPVETDPDRAVAIGIIVNELVMNAVKYAYPEGKGPIHVELKADGDDLELVIADEGVGLNVKANPQSTGMGQRI
VSAMAAKLEADVERDPNHSGTRMVLRFRRANATAAAAPEPATP
>Mature_362_residues
TDAKPTLLYIDDDEALGRLVSRGLQRQGFCVEHVLSGEAGLERLRQGGIDVIALDQYMPGLDGLETLEQIQAIPDPPPVV
FVTASQDSKIAVTALKAGADDYLVKDTQGEFVPLLQVAADQALKQAMVRKARDDAEAEVRASRDRYAALAAEREMLLREV
NHRVGNSLQIIASLLHLQASSSKQDEVKAALTNAMGRVAAVAQVHRRLYTSHDLKSVMLNQYLESLLEDLRRSAEGNRMS
RLTLSAQPVETDPDRAVAIGIIVNELVMNAVKYAYPEGKGPIHVELKADGDDLELVIADEGVGLNVKANPQSTGMGQRIV
SAMAAKLEADVERDPNHSGTRMVLRFRRANATAAAAPEPATP

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=152, Percent_Identity=32.2368421052632, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790437, Length=106, Percent_Identity=35.8490566037736, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39341; Mature: 39210

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAKPTLLYIDDDEALGRLVSRGLQRQGFCVEHVLSGEAGLERLRQGGIDVIALDQYMP
CCCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHCCCCEEEECCCCC
GLDGLETLEQIQAIPDPPPVVFVTASQDSKIAVTALKAGADDYLVKDTQGEFVPLLQVAA
CCCHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEECCCCCCEEECCCCCHHHHHHHHH
DQALKQAMVRKARDDAEAEVRASRDRYAALAAEREMLLREVNHRVGNSLQIIASLLHLQA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
SSSKQDEVKAALTNAMGRVAAVAQVHRRLYTSHDLKSVMLNQYLESLLEDLRRSAEGNRM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
SRLTLSAQPVETDPDRAVAIGIIVNELVMNAVKYAYPEGKGPIHVELKADGDDLELVIAD
EEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEC
EGVGLNVKANPQSTGMGQRIVSAMAAKLEADVERDPNHSGTRMVLRFRRANATAAAAPEP
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEHEEEHHCCCCCCCCCCC
ATP
CCC
>Mature Secondary Structure 
TDAKPTLLYIDDDEALGRLVSRGLQRQGFCVEHVLSGEAGLERLRQGGIDVIALDQYMP
CCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHCCCCEEEECCCCC
GLDGLETLEQIQAIPDPPPVVFVTASQDSKIAVTALKAGADDYLVKDTQGEFVPLLQVAA
CCCHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEECCCCCCEEECCCCCHHHHHHHHH
DQALKQAMVRKARDDAEAEVRASRDRYAALAAEREMLLREVNHRVGNSLQIIASLLHLQA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
SSSKQDEVKAALTNAMGRVAAVAQVHRRLYTSHDLKSVMLNQYLESLLEDLRRSAEGNRM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
SRLTLSAQPVETDPDRAVAIGIIVNELVMNAVKYAYPEGKGPIHVELKADGDDLELVIAD
EEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEC
EGVGLNVKANPQSTGMGQRIVSAMAAKLEADVERDPNHSGTRMVLRFRRANATAAAAPEP
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEHEEEHHCCCCCCCCCCC
ATP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]