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The map label for this gene is asbF [H]

Identifier: 192291009

GI number: 192291009

Start: 2845198

End: 2846067

Strand: Reverse

Name: asbF [H]

Synonym: Rpal_2628

Alternate gene names: 192291009

Gene position: 2846067-2845198 (Counterclockwise)

Preceding gene: 192291010

Following gene: 192291008

Centisome position: 49.55

GC content: 62.87

Gene sequence:

>870_bases
ATGAAACTCTCGGTCTGCACCATCACATTCCGCCATCACCTGCTCTGCTTCAGCGAGATCGTCGAGTGGACGCGACGCAA
CGGCTTCGACGGCGTCGAACTGTGGGGCGCTCATGCGCGCGGCCTAATGCGGACGCACCCGGAATACGATGCAGACTGGC
TTCGCAGTTACGGCCTGTCGGTGCCGATGCTGAGCGATTACCTGCCGACCGACGTCGACATCACGGACACTCGCCACCGT
GCAATCGAGCTCTGCCGGATTGCACAGCATTGGTCGGCGCGAAAGATCCGCACCTTCGCCGGTAACAGACCGAGCGCCCA
GCTGGCGCGCGAGCAGCGCAGAGCGCTGGCCGGCCGGATCGGTGAGATCGCCGGCATCGTCCATGATCACGGCATCCGGC
TGTTGGTCGAGACACACCCGAACACGCTGGCCGACAGCGTCGACTCGACACTGGGCCTGTTGGCGGATGCCAACCACCCA
GGTCTCGGTATTAACTTCGATGCTCTGCACGTCTGGGAAGGTGGCGATGATCCCGTTCTGGCGCGCCGCACGCTCGCGGA
CTTCATCGGGCACTATCATCTCAAGAATGTTCGATCACGCGACGAGCTCCACGTGTTCTTCCCGGACAACGTCTATTCCG
CCGCCGGCTCCCGTGACGGCATGGTGCCGCTGTTTGACGGCGCGATGGATTACGAAGGTTTCCTCGCATCCTTGGCGGAC
GAAAGTAACGCGGAGGCATCACTCGAATGGTTCGGCAACGACGGCTTCGAGACGTTGACCCGCGATCGGCTGGCCATTCT
CTCACACTTCACTTCGGCAAGGGGCGGCGCCGGATCCGCACGCGATCGCCGGCCACGTCGCCTCAGCTAA

Upstream 100 bases:

>100_bases
CCGCGATCAAGGTCAAGCTGCACGAGGTGTTCGTCGCCTGGTGCGCCCATCAAGGTCTCACCGGGGCGACGCCCCGCGAA
CGCCTTGTCGGTGTACGGTG

Downstream 100 bases:

>100_bases
AGGACAATCATGTATGTGATCCGCATAATCGCCGTGCTGGCAGCCCTCGCTCTGCCTGCGTCGGCCGTCGCTGAAACGAT
CGATATCCAGACCGCACAGG

Product: xylose isomerase

Products: NA

Alternate protein names: 3-DHS dehydratase; DHSase; Petrobactin biosynthesis protein AsbF [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MKLSVCTITFRHHLLCFSEIVEWTRRNGFDGVELWGAHARGLMRTHPEYDADWLRSYGLSVPMLSDYLPTDVDITDTRHR
AIELCRIAQHWSARKIRTFAGNRPSAQLAREQRRALAGRIGEIAGIVHDHGIRLLVETHPNTLADSVDSTLGLLADANHP
GLGINFDALHVWEGGDDPVLARRTLADFIGHYHLKNVRSRDELHVFFPDNVYSAAGSRDGMVPLFDGAMDYEGFLASLAD
ESNAEASLEWFGNDGFETLTRDRLAILSHFTSARGGAGSARDRRPRRLS

Sequences:

>Translated_289_residues
MKLSVCTITFRHHLLCFSEIVEWTRRNGFDGVELWGAHARGLMRTHPEYDADWLRSYGLSVPMLSDYLPTDVDITDTRHR
AIELCRIAQHWSARKIRTFAGNRPSAQLAREQRRALAGRIGEIAGIVHDHGIRLLVETHPNTLADSVDSTLGLLADANHP
GLGINFDALHVWEGGDDPVLARRTLADFIGHYHLKNVRSRDELHVFFPDNVYSAAGSRDGMVPLFDGAMDYEGFLASLAD
ESNAEASLEWFGNDGFETLTRDRLAILSHFTSARGGAGSARDRRPRRLS
>Mature_289_residues
MKLSVCTITFRHHLLCFSEIVEWTRRNGFDGVELWGAHARGLMRTHPEYDADWLRSYGLSVPMLSDYLPTDVDITDTRHR
AIELCRIAQHWSARKIRTFAGNRPSAQLAREQRRALAGRIGEIAGIVHDHGIRLLVETHPNTLADSVDSTLGLLADANHP
GLGINFDALHVWEGGDDPVLARRTLADFIGHYHLKNVRSRDELHVFFPDNVYSAAGSRDGMVPLFDGAMDYEGFLASLAD
ESNAEASLEWFGNDGFETLTRDRLAILSHFTSARGGAGSARDRRPRRLS

Specific function: Converts 3-dehydroshikimate to protocatechuate (3,4- dihydroxybenzoate), a biosynthetic unit required for the biosynthesis of petrobactin which is a virulence-associated siderophore produced by B.anthracis [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.118 [H]

Molecular weight: Translated: 32341; Mature: 32341

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSVCTITFRHHLLCFSEIVEWTRRNGFDGVELWGAHARGLMRTHPEYDADWLRSYGLS
CCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHCCCCCCHHHHHHCCCC
VPMLSDYLPTDVDITDTRHRAIELCRIAQHWSARKIRTFAGNRPSAQLAREQRRALAGRI
CCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GEIAGIVHDHGIRLLVETHPNTLADSVDSTLGLLADANHPGLGINFDALHVWEGGDDPVL
HHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHH
ARRTLADFIGHYHLKNVRSRDELHVFFPDNVYSAAGSRDGMVPLFDGAMDYEGFLASLAD
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHCCCCCCCCCEEECCCCCHHHHHHHHHC
ESNAEASLEWFGNDGFETLTRDRLAILSHFTSARGGAGSARDRRPRRLS
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLSVCTITFRHHLLCFSEIVEWTRRNGFDGVELWGAHARGLMRTHPEYDADWLRSYGLS
CCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHCCCCCCHHHHHHCCCC
VPMLSDYLPTDVDITDTRHRAIELCRIAQHWSARKIRTFAGNRPSAQLAREQRRALAGRI
CCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GEIAGIVHDHGIRLLVETHPNTLADSVDSTLGLLADANHPGLGINFDALHVWEGGDDPVL
HHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHH
ARRTLADFIGHYHLKNVRSRDELHVFFPDNVYSAAGSRDGMVPLFDGAMDYEGFLASLAD
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHCCCCCCCCCEEECCCCCHHHHHHHHHC
ESNAEASLEWFGNDGFETLTRDRLAILSHFTSARGGAGSARDRRPRRLS
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]