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The map label for this gene is ctpC [H]

Identifier: 192290960

GI number: 192290960

Start: 2786836

End: 2788932

Strand: Reverse

Name: ctpC [H]

Synonym: Rpal_2577

Alternate gene names: 192290960

Gene position: 2788932-2786836 (Counterclockwise)

Preceding gene: 192290961

Following gene: 192290947

Centisome position: 48.55

GC content: 66.91

Gene sequence:

>2097_bases
ATGACCGATAAGCGGTGGCTGTCGGCAGTCGAGATCGTTCACCGCCTGCCCGGCCGCATCCGCTTGCGCTATCAGCGCCG
CTCCAAGACTTCGGACCCTGCTCTCCTCGCCGGCATCGTAAGGCTGATCGATGGCGTGACCGCAGCGCGCGTCAATTCCC
GCGCTGCGTCGCTGATCGTGTATTTCGATCCGGCGCGCACCGACGCCGACACCATCGTCACGACGATCGCAAGCCTCGAG
GCGTCGGAGGCAGGCGCGAATTCGCGAAGCGACGACGGCGGTTCGGACGTCGCCGCGACGCTCGCCGTCCTGCTCGGAAC
GAGCGCGCTGCCGATGCAGGCGCGACTTCCGGTCAGCCTCGCCGCTGCGCTTCCGCTGCTCCGCCATGCGGCGTCAGACC
TTCGCACCCATGGCGTCACCAGCCACGTGCTGGAGGCGATGGCCGTGTCGATCTCGCTGGCGCGCGCCGACTTCGTCGCC
GCCAACACCACGACGTTCATCCTGGCGCTCGGCGAAGCAATCGAAGATTCCATTGCGCGCCGTTCCGACGATCTGCTCAA
GCACCTGCTGCGCCCGACCAGCGACGGCGTCTGGGTTCTGCGCGACGGCGTCGAAGTGCAGATTTCCGCCGACGAGGTGA
CGGCCGGCGATACGGTGGTCGTCGGCGCCGGGGCGGTCGTTCCGATCGATGGCACCGTTCTGTCCGGCGAAGCCACCGTC
AATGAGGCGGCGATGACCGGCGAGAGCGCGCCGGTCGTCAAGAGCCGCGGCAGCAAGGTTCTGTCCGGCACCATGCTGGA
GGACGGCCGCCTGACGATCTATGCCGAGCAGGTCGGCCGCCGAACCTCCGCCGCGCGGATCGCAGACTATGTCGAGCAGT
CGCTGACCGCGAAAAGTGAGGCACAGATCGAAGCCGCCCGCCTCGCCGACCGTCTGGTGCCCACCGTGCTGAAGCTCGCC
GGCTTCTCCGTGCTGCTCACCGGCGACTGGCGCTCGGCCGCCTCGGTGCTGCAGGCGGACTACTCCTGCGCGTTGAAGCT
GGCGACGCCGGTCGCCTTCAAGTCCGCGATGTATCACGCCGGCCGGATCGGCATTCTGGTCAAGGGCGCGAGTGCGCTCG
AACGCCTCGCCCGGGCCGACACCTTCATCTTCGACAAGACCGGCACGCTGACCACCGGCACCTTGGAGGTCACGGACTCG
GTCACCTTCGACTCCGCCTACAGCGCAGACGACCTGATCTGCTTGGCCGCGTCGGTTGAAGAGCACTACTTCCATCCCTT
AGCGCTCGCGGTGGTGAACGCCGCCAAAGCCAGGCACGGCCACCATTTCGATCATGCGGAGGTGGAGTTCATCGTGGCCC
ACGGCGTCGCCAGTGTCATCAACGGCGAACGCATCGTCGTCGGCTCGCGCCATTTCGTCGAAGAAGACGAAGGCATCGAT
ATCTCGCTCCATCGAGATCCGATCGATCGTCTGTATCGCGAAGGCAAGACGCTGCTGTTCATCGGCTTCGGCGGGCGCCT
ACTCGGCGTCCTCGGACTGAAAGACACGGTTCGCCCGACCAGCGCCGCCACCATCGCACGCCTGCGCCGCGCCGGCGCCA
AGCGCATTCTGCTGCTGACCGGCGATCACCGCGACCGCGCGGCCGAAATGGCGCAGGAGCTCCGGCTCGACGGCTTTCAT
GCCGAGCTGCTGCCGACCGACAAGGCCGCGATCATTGCCGACCTCAATGCCAAGGGCGCCAAGATCGCGTTCGTCGGTGA
CGGCATCAACGACGCGCCGGCGCTGGCAGGCGCCCATGTCGGCATCGCCATGCACAAGGGCGCGGACATCGCGCGGCTCA
CCGCCGATATCGCCCTGCTCGAAGATGGCGTCGACCGCGTCGCCGACGCCAAGGAGCTCGCCAATCGCGCGATGGCTCGG
ATCGCCAGCAACTATAAACTGACGGTCGGCCTCAACACCACGATCCTGGGGCTCGCAGCGATGGGCGTGCTGGCTCCGAT
CACGACCGCCGTCCTGCACAACGGCACGACAATCGGAATCCTGCTGAACGCACTCCGGAATGCGATGCCGAGGGTGCCCG
CTGCCCCCAGTGTCTGA

Upstream 100 bases:

>100_bases
CAATCAAAGCCTACGCCAACATGATGGGCAGCGTCGCCGAGTTGAAGGAACAGTTCGCCGACCTGAGTGCGGAAGTCGAG
GCCGAACAGAGCGGCACCGT

Downstream 100 bases:

>100_bases
TCTCGTTCGCATCAAAGAAATGGCTCAGGCAGCACCCCGCCTGCGCCATCCGTCACGATCGATAGCAATGTCGAGTTCGT
GCAAGAACTCGCCGTCGGCG

Product: ATPase P

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 698; Mature: 697

Protein sequence:

>698_residues
MTDKRWLSAVEIVHRLPGRIRLRYQRRSKTSDPALLAGIVRLIDGVTAARVNSRAASLIVYFDPARTDADTIVTTIASLE
ASEAGANSRSDDGGSDVAATLAVLLGTSALPMQARLPVSLAAALPLLRHAASDLRTHGVTSHVLEAMAVSISLARADFVA
ANTTTFILALGEAIEDSIARRSDDLLKHLLRPTSDGVWVLRDGVEVQISADEVTAGDTVVVGAGAVVPIDGTVLSGEATV
NEAAMTGESAPVVKSRGSKVLSGTMLEDGRLTIYAEQVGRRTSAARIADYVEQSLTAKSEAQIEAARLADRLVPTVLKLA
GFSVLLTGDWRSAASVLQADYSCALKLATPVAFKSAMYHAGRIGILVKGASALERLARADTFIFDKTGTLTTGTLEVTDS
VTFDSAYSADDLICLAASVEEHYFHPLALAVVNAAKARHGHHFDHAEVEFIVAHGVASVINGERIVVGSRHFVEEDEGID
ISLHRDPIDRLYREGKTLLFIGFGGRLLGVLGLKDTVRPTSAATIARLRRAGAKRILLLTGDHRDRAAEMAQELRLDGFH
AELLPTDKAAIIADLNAKGAKIAFVGDGINDAPALAGAHVGIAMHKGADIARLTADIALLEDGVDRVADAKELANRAMAR
IASNYKLTVGLNTTILGLAAMGVLAPITTAVLHNGTTIGILLNALRNAMPRVPAAPSV

Sequences:

>Translated_698_residues
MTDKRWLSAVEIVHRLPGRIRLRYQRRSKTSDPALLAGIVRLIDGVTAARVNSRAASLIVYFDPARTDADTIVTTIASLE
ASEAGANSRSDDGGSDVAATLAVLLGTSALPMQARLPVSLAAALPLLRHAASDLRTHGVTSHVLEAMAVSISLARADFVA
ANTTTFILALGEAIEDSIARRSDDLLKHLLRPTSDGVWVLRDGVEVQISADEVTAGDTVVVGAGAVVPIDGTVLSGEATV
NEAAMTGESAPVVKSRGSKVLSGTMLEDGRLTIYAEQVGRRTSAARIADYVEQSLTAKSEAQIEAARLADRLVPTVLKLA
GFSVLLTGDWRSAASVLQADYSCALKLATPVAFKSAMYHAGRIGILVKGASALERLARADTFIFDKTGTLTTGTLEVTDS
VTFDSAYSADDLICLAASVEEHYFHPLALAVVNAAKARHGHHFDHAEVEFIVAHGVASVINGERIVVGSRHFVEEDEGID
ISLHRDPIDRLYREGKTLLFIGFGGRLLGVLGLKDTVRPTSAATIARLRRAGAKRILLLTGDHRDRAAEMAQELRLDGFH
AELLPTDKAAIIADLNAKGAKIAFVGDGINDAPALAGAHVGIAMHKGADIARLTADIALLEDGVDRVADAKELANRAMAR
IASNYKLTVGLNTTILGLAAMGVLAPITTAVLHNGTTIGILLNALRNAMPRVPAAPSV
>Mature_697_residues
TDKRWLSAVEIVHRLPGRIRLRYQRRSKTSDPALLAGIVRLIDGVTAARVNSRAASLIVYFDPARTDADTIVTTIASLEA
SEAGANSRSDDGGSDVAATLAVLLGTSALPMQARLPVSLAAALPLLRHAASDLRTHGVTSHVLEAMAVSISLARADFVAA
NTTTFILALGEAIEDSIARRSDDLLKHLLRPTSDGVWVLRDGVEVQISADEVTAGDTVVVGAGAVVPIDGTVLSGEATVN
EAAMTGESAPVVKSRGSKVLSGTMLEDGRLTIYAEQVGRRTSAARIADYVEQSLTAKSEAQIEAARLADRLVPTVLKLAG
FSVLLTGDWRSAASVLQADYSCALKLATPVAFKSAMYHAGRIGILVKGASALERLARADTFIFDKTGTLTTGTLEVTDSV
TFDSAYSADDLICLAASVEEHYFHPLALAVVNAAKARHGHHFDHAEVEFIVAHGVASVINGERIVVGSRHFVEEDEGIDI
SLHRDPIDRLYREGKTLLFIGFGGRLLGVLGLKDTVRPTSAATIARLRRAGAKRILLLTGDHRDRAAEMAQELRLDGFHA
ELLPTDKAAIIADLNAKGAKIAFVGDGINDAPALAGAHVGIAMHKGADIARLTADIALLEDGVDRVADAKELANRAMARI
ASNYKLTVGLNTTILGLAAMGVLAPITTAVLHNGTTIGILLNALRNAMPRVPAAPSV

Specific function: Involved In Export Of Lead, Cadmium, Zinc And Mercury. [C]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=533, Percent_Identity=29.0806754221388, Blast_Score=190, Evalue=5e-48,
Organism=Homo sapiens, GI115529486, Length=549, Percent_Identity=26.4116575591985, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI55743073, Length=503, Percent_Identity=29.4234592445328, Blast_Score=186, Evalue=7e-47,
Organism=Escherichia coli, GI1789879, Length=542, Percent_Identity=33.210332103321, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1786691, Length=521, Percent_Identity=31.8618042226488, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1786914, Length=435, Percent_Identity=32.183908045977, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI2367363, Length=171, Percent_Identity=30.4093567251462, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17556548, Length=593, Percent_Identity=27.8246205733558, Blast_Score=158, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6320475, Length=508, Percent_Identity=28.3464566929134, Blast_Score=183, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6319772, Length=506, Percent_Identity=26.4822134387352, Blast_Score=150, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6325221, Length=624, Percent_Identity=26.9230769230769, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321430, Length=600, Percent_Identity=27.3333333333333, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI221329854, Length=263, Percent_Identity=34.2205323193916, Blast_Score=126, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: 3.6.3.3 [C]

Molecular weight: Translated: 73571; Mature: 73440

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKRWLSAVEIVHRLPGRIRLRYQRRSKTSDPALLAGIVRLIDGVTAARVNSRAASLIV
CCCHHHHHHHHHHHHCCCCEEEEEHHCCCCCCHHHHHHHHHHHCCHHHHHHCCCEEEEEE
YFDPARTDADTIVTTIASLEASEAGANSRSDDGGSDVAATLAVLLGTSALPMQARLPVSL
EECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHH
AAALPLLRHAASDLRTHGVTSHVLEAMAVSISLARADFVAANTTTFILALGEAIEDSIAR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEHHHHHHHHHHH
RSDDLLKHLLRPTSDGVWVLRDGVEVQISADEVTAGDTVVVGAGAVVPIDGTVLSGEATV
CHHHHHHHHHCCCCCCEEEEECCEEEEEECCCCCCCCEEEEECCEEEECCCEEECCCCCC
NEAAMTGESAPVVKSRGSKVLSGTMLEDGRLTIYAEQVGRRTSAARIADYVEQSLTAKSE
CHHHHCCCCCCHHHCCCCEEEECEEECCCCEEEEEHHHCCCHHHHHHHHHHHHHHCCCHH
AQIEAARLADRLVPTVLKLAGFSVLLTGDWRSAASVLQADYSCALKLATPVAFKSAMYHA
HHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCEEEEECCHHHHHHHHHCC
GRIGILVKGASALERLARADTFIFDKTGTLTTGTLEVTDSVTFDSAYSADDLICLAASVE
CCEEEEEECHHHHHHHHHCCCEEEECCCCEEEEEEEEECCEEECCCCCCCCEEEEEEHHH
EHYFHPLALAVVNAAKARHGHHFDHAEVEFIVAHGVASVINGERIVVGSRHFVEEDEGID
HHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHCCCEEEECCCCCCCCCCCCE
ISLHRDPIDRLYREGKTLLFIGFGGRLLGVLGLKDTVRPTSAATIARLRRAGAKRILLLT
EEECCCHHHHHHHCCCEEEEEECCHHHHEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEE
GDHRDRAAEMAQELRLDGFHAELLPTDKAAIIADLNAKGAKIAFVGDGINDAPALAGAHV
CCCHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCEEEEEECCCCCCCHHCCCEE
GIAMHKGADIARLTADIALLEDGVDRVADAKELANRAMARIASNYKLTVGLNTTILGLAA
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHH
MGVLAPITTAVLHNGTTIGILLNALRNAMPRVPAAPSV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TDKRWLSAVEIVHRLPGRIRLRYQRRSKTSDPALLAGIVRLIDGVTAARVNSRAASLIV
CCHHHHHHHHHHHHCCCCEEEEEHHCCCCCCHHHHHHHHHHHCCHHHHHHCCCEEEEEE
YFDPARTDADTIVTTIASLEASEAGANSRSDDGGSDVAATLAVLLGTSALPMQARLPVSL
EECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHH
AAALPLLRHAASDLRTHGVTSHVLEAMAVSISLARADFVAANTTTFILALGEAIEDSIAR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEHHHHHHHHHHH
RSDDLLKHLLRPTSDGVWVLRDGVEVQISADEVTAGDTVVVGAGAVVPIDGTVLSGEATV
CHHHHHHHHHCCCCCCEEEEECCEEEEEECCCCCCCCEEEEECCEEEECCCEEECCCCCC
NEAAMTGESAPVVKSRGSKVLSGTMLEDGRLTIYAEQVGRRTSAARIADYVEQSLTAKSE
CHHHHCCCCCCHHHCCCCEEEECEEECCCCEEEEEHHHCCCHHHHHHHHHHHHHHCCCHH
AQIEAARLADRLVPTVLKLAGFSVLLTGDWRSAASVLQADYSCALKLATPVAFKSAMYHA
HHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCEEEEECCHHHHHHHHHCC
GRIGILVKGASALERLARADTFIFDKTGTLTTGTLEVTDSVTFDSAYSADDLICLAASVE
CCEEEEEECHHHHHHHHHCCCEEEECCCCEEEEEEEEECCEEECCCCCCCCEEEEEEHHH
EHYFHPLALAVVNAAKARHGHHFDHAEVEFIVAHGVASVINGERIVVGSRHFVEEDEGID
HHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHCCCEEEECCCCCCCCCCCCE
ISLHRDPIDRLYREGKTLLFIGFGGRLLGVLGLKDTVRPTSAATIARLRRAGAKRILLLT
EEECCCHHHHHHHCCCEEEEEECCHHHHEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEE
GDHRDRAAEMAQELRLDGFHAELLPTDKAAIIADLNAKGAKIAFVGDGINDAPALAGAHV
CCCHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCEEEEEECCCCCCCHHCCCEE
GIAMHKGADIARLTADIALLEDGVDRVADAKELANRAMARIASNYKLTVGLNTTILGLAA
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHH
MGVLAPITTAVLHNGTTIGILLNALRNAMPRVPAAPSV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]