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The map label for this gene is hfaC [H]

Identifier: 192290868

GI number: 192290868

Start: 2678778

End: 2680595

Strand: Reverse

Name: hfaC [H]

Synonym: Rpal_2484

Alternate gene names: 192290868

Gene position: 2680595-2678778 (Counterclockwise)

Preceding gene: 192290869

Following gene: 192290867

Centisome position: 46.67

GC content: 68.48

Gene sequence:

>1818_bases
ATGGCGCCGCCGCTGATCCAACTGAAAGACATCGCGCTGACGTTTGGCGGCGCCGCGCTGTTCGACGGCGTCGAACTCGC
CGTCTCCGCCGGCGACCGGCTGTGCCTGATCGGCCGCAACGGCTCCGGCAAGTCGACGCTGCTCAAGATCGTCGCCGGCC
TGATCGAGCCCGATCGCGGCAGCCGCTTCGTGCAGCCCGGCGCCACCGTGCGCTATCTGCCGCAGGAGCCGGATTTCGAC
GGCTTCGCCACCACGCTGGCCTATGTCGAGGCCGGGCTCGCGCCGGGCGACGATCACTATCAGGCCGCCTATCTGCTCGA
ACAGCTCGGCCTGCACGGCGACGAGAACCCCGCTCATCTGTCCGGCGGCGAGGCCCGTCGCGCGGCGCTGGCGCGGATTC
TGGCACCCGATCCCGACATCCTGCTGCTCGACGAGCCGACCAACCATCTCGACCTGACGACGATCGAATGGCTGGAAAAC
GATCTCGCCCAGCGCAGATGCGCGATCGTGATGATCAGCCACGACCGCCGTTTCCTGAGCAATCTGTCGCGCGCCACCGC
CTGGCTCGACCGCGGCGTGATCCGCCAGATCGACCGCGGCTTCTCGCAGTTCGAAAGCTGGCGCGACGACGTGCTGGCCG
AGGAAGAGCGCGATCAGCACAAGCTCGACCGCAAGATCGTGATGGAAGAGCACTGGCTGCGCTACGGCGTCTCCGGCCGC
CGCAAGCGCAACGTCAAGCGGCTGGCCGGCCTGCACGAGCTGCGCGCCCAGCGCCGCGACTATCGCGGACCGACCGGGGC
GGCTTCGCTCGCCGCGGCCGAGGCCGACAAGTCCGGCAAGCTGGTGATCGAAGCCAAGTCGATCAGCAAGGCCTGGGGCG
ACCGCCCGATCGTCGACGCCTTCTCGATAAGGATCAATCGCGGCGACCGCGTCGGCATCGTCGGGCCGAACGGCGCCGGC
AAGACCACGCTGATCAGCCTGCTGACCGGCGCGCTTGCCCCCGACAGCGGCACGGTGCGGCTCGGCACCAATCTGGAGAT
CGCCACGCTGGACCAGAGCCGCGACAGCTTGGATCCGAAATCGACGCTGAGCGACGCGCTGACCGGCGGCCGCGGCGACC
AGGTGATGGTCGGCGGCAAGCCTCGCCATGTGATCGGCTACATGAAGGACTTCCTGTTCACCCAGGAGCAGGCGCGCACG
CCGCTGGAGGCGCTATCCGGCGGCGAACGCGGCCGGCTGATGCTTGCGCGCTCGCTAGCCAACCCGTCGAACCTGCTCGT
GCTCGACGAGCCGACCAACGACCTCGATCTCGAAACCCTCGACGTGCTCGAGGAGATGCTCGGCGACTACGACGGCACGG
TGATCCTGATCAGCCACGACCGCGACTTTCTCGACCGGGTCGTCACCTCGGTGATCGCGCCGGACGGCGGCGGCAAATGG
ATCGAATACGCCGGCGGCTATTCCGACATGCTGGCGCAGCGCGGCGCCGACCTGAGCCGGCAGCCGGCCAAGGCCGCCGC
GGCCGAGCCGGCCGCCGCGAAGGCAGCTCCCTCGCCCGCCACCGCGCCGGCGCCGAAGCGCAAGCTGAGCTTCAACGAGA
AGCACGCTCTCGAAACCCTGCCCAAGACCATCGCCAAGCTGGAGGCCGAGATCGCCGACCTGCAGAAGCAGCTTGATGAT
CCGCAGCTGTTCGCCCGCGACCGCGCCAAGTTCGACAAGGTCTCGGCCGCGATGGCCAAGGCTCACGACGCGCTGCACGC
CTCCGAGCATCGCTGGCTCGAGCTGGAAATGCTGCGCGAAGAGATCGAAAGCGCCTGA

Upstream 100 bases:

>100_bases
GCGTTTTCGCCGCGCGACCGCTCCACCTTTCTTTCGGCGCTCGATAGCGCGATCCGCAGGATCGCGCGCCGCAGGGCCGC
TCCGACCTGATGGACCGAAT

Downstream 100 bases:

>100_bases
TAAGGCCTGTTCCGAAGCTTTGAACGGTACTTAATCACCACGTCGACTGAGCGGATTGACTCGGCGCGTGCCTGAGTTTA
TATCTACACTTGTGGATATA

Product: ABC transporter

Products: NA

Alternate protein names: Protein HfaC [H]

Number of amino acids: Translated: 605; Mature: 604

Protein sequence:

>605_residues
MAPPLIQLKDIALTFGGAALFDGVELAVSAGDRLCLIGRNGSGKSTLLKIVAGLIEPDRGSRFVQPGATVRYLPQEPDFD
GFATTLAYVEAGLAPGDDHYQAAYLLEQLGLHGDENPAHLSGGEARRAALARILAPDPDILLLDEPTNHLDLTTIEWLEN
DLAQRRCAIVMISHDRRFLSNLSRATAWLDRGVIRQIDRGFSQFESWRDDVLAEEERDQHKLDRKIVMEEHWLRYGVSGR
RKRNVKRLAGLHELRAQRRDYRGPTGAASLAAAEADKSGKLVIEAKSISKAWGDRPIVDAFSIRINRGDRVGIVGPNGAG
KTTLISLLTGALAPDSGTVRLGTNLEIATLDQSRDSLDPKSTLSDALTGGRGDQVMVGGKPRHVIGYMKDFLFTQEQART
PLEALSGGERGRLMLARSLANPSNLLVLDEPTNDLDLETLDVLEEMLGDYDGTVILISHDRDFLDRVVTSVIAPDGGGKW
IEYAGGYSDMLAQRGADLSRQPAKAAAAEPAAAKAAPSPATAPAPKRKLSFNEKHALETLPKTIAKLEAEIADLQKQLDD
PQLFARDRAKFDKVSAAMAKAHDALHASEHRWLELEMLREEIESA

Sequences:

>Translated_605_residues
MAPPLIQLKDIALTFGGAALFDGVELAVSAGDRLCLIGRNGSGKSTLLKIVAGLIEPDRGSRFVQPGATVRYLPQEPDFD
GFATTLAYVEAGLAPGDDHYQAAYLLEQLGLHGDENPAHLSGGEARRAALARILAPDPDILLLDEPTNHLDLTTIEWLEN
DLAQRRCAIVMISHDRRFLSNLSRATAWLDRGVIRQIDRGFSQFESWRDDVLAEEERDQHKLDRKIVMEEHWLRYGVSGR
RKRNVKRLAGLHELRAQRRDYRGPTGAASLAAAEADKSGKLVIEAKSISKAWGDRPIVDAFSIRINRGDRVGIVGPNGAG
KTTLISLLTGALAPDSGTVRLGTNLEIATLDQSRDSLDPKSTLSDALTGGRGDQVMVGGKPRHVIGYMKDFLFTQEQART
PLEALSGGERGRLMLARSLANPSNLLVLDEPTNDLDLETLDVLEEMLGDYDGTVILISHDRDFLDRVVTSVIAPDGGGKW
IEYAGGYSDMLAQRGADLSRQPAKAAAAEPAAAKAAPSPATAPAPKRKLSFNEKHALETLPKTIAKLEAEIADLQKQLDD
PQLFARDRAKFDKVSAAMAKAHDALHASEHRWLELEMLREEIESA
>Mature_604_residues
APPLIQLKDIALTFGGAALFDGVELAVSAGDRLCLIGRNGSGKSTLLKIVAGLIEPDRGSRFVQPGATVRYLPQEPDFDG
FATTLAYVEAGLAPGDDHYQAAYLLEQLGLHGDENPAHLSGGEARRAALARILAPDPDILLLDEPTNHLDLTTIEWLEND
LAQRRCAIVMISHDRRFLSNLSRATAWLDRGVIRQIDRGFSQFESWRDDVLAEEERDQHKLDRKIVMEEHWLRYGVSGRR
KRNVKRLAGLHELRAQRRDYRGPTGAASLAAAEADKSGKLVIEAKSISKAWGDRPIVDAFSIRINRGDRVGIVGPNGAGK
TTLISLLTGALAPDSGTVRLGTNLEIATLDQSRDSLDPKSTLSDALTGGRGDQVMVGGKPRHVIGYMKDFLFTQEQARTP
LEALSGGERGRLMLARSLANPSNLLVLDEPTNDLDLETLDVLEEMLGDYDGTVILISHDRDFLDRVVTSVIAPDGGGKWI
EYAGGYSDMLAQRGADLSRQPAKAAAAEPAAAKAAPSPATAPAPKRKLSFNEKHALETLPKTIAKLEAEIADLQKQLDDP
QLFARDRAKFDKVSAAMAKAHDALHASEHRWLELEMLREEIESA

Specific function: Involved in attachment of the holdfast to the cell. The holdfast is a structure that allows the bacteria to firmly adhere to surfaces [H]

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=531, Percent_Identity=28.060263653484, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI27881506, Length=548, Percent_Identity=27.9197080291971, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI10947137, Length=548, Percent_Identity=27.9197080291971, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI10947135, Length=515, Percent_Identity=27.5728155339806, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI69354671, Length=515, Percent_Identity=27.5728155339806, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI105990541, Length=263, Percent_Identity=28.1368821292776, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI21536376, Length=200, Percent_Identity=29.5, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1787182, Length=634, Percent_Identity=39.7476340694006, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI2367384, Length=537, Percent_Identity=35.195530726257, Blast_Score=285, Evalue=6e-78,
Organism=Escherichia coli, GI1787041, Length=542, Percent_Identity=28.4132841328413, Blast_Score=219, Evalue=5e-58,
Organism=Escherichia coli, GI1789751, Length=647, Percent_Identity=27.8207109737249, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI87081782, Length=469, Percent_Identity=25.1599147121535, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788225, Length=219, Percent_Identity=30.5936073059361, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI48994943, Length=592, Percent_Identity=23.8175675675676, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788165, Length=226, Percent_Identity=28.3185840707965, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787712, Length=215, Percent_Identity=29.3023255813954, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1788761, Length=220, Percent_Identity=31.8181818181818, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787029, Length=214, Percent_Identity=28.9719626168224, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081791, Length=207, Percent_Identity=29.4685990338164, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787370, Length=214, Percent_Identity=29.9065420560748, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1786319, Length=208, Percent_Identity=29.8076923076923, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786253, Length=199, Percent_Identity=32.1608040201005, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787758, Length=196, Percent_Identity=30.6122448979592, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1787112, Length=221, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786563, Length=188, Percent_Identity=29.7872340425532, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081709, Length=218, Percent_Identity=26.1467889908257, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789032, Length=198, Percent_Identity=30.3030303030303, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786872, Length=216, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081834, Length=197, Percent_Identity=27.4111675126904, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787164, Length=185, Percent_Identity=30.2702702702703, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787105, Length=222, Percent_Identity=28.8288288288288, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786398, Length=217, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790739, Length=214, Percent_Identity=26.6355140186916, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789873, Length=215, Percent_Identity=26.9767441860465, Blast_Score=63, Evalue=7e-11,
Organism=Escherichia coli, GI87082267, Length=214, Percent_Identity=28.5046728971963, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI48995001, Length=205, Percent_Identity=26.8292682926829, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17555318, Length=531, Percent_Identity=26.7419962335217, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17559834, Length=528, Percent_Identity=25.3787878787879, Blast_Score=150, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17553372, Length=513, Percent_Identity=27.8752436647173, Blast_Score=134, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320874, Length=540, Percent_Identity=26.2962962962963, Blast_Score=153, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6321121, Length=393, Percent_Identity=28.498727735369, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324314, Length=354, Percent_Identity=27.683615819209, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6323278, Length=354, Percent_Identity=28.2485875706215, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6325030, Length=353, Percent_Identity=29.1784702549575, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24642252, Length=554, Percent_Identity=28.7003610108303, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI18859989, Length=554, Percent_Identity=28.7003610108303, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24666836, Length=516, Percent_Identity=28.4883720930233, Blast_Score=165, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24641342, Length=513, Percent_Identity=26.9005847953216, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI116007184, Length=182, Percent_Identity=30.2197802197802, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221500365, Length=182, Percent_Identity=30.2197802197802, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI85725262, Length=150, Percent_Identity=32.6666666666667, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24666092, Length=169, Percent_Identity=32.5443786982249, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR007406 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 65955; Mature: 65824

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPPLIQLKDIALTFGGAALFDGVELAVSAGDRLCLIGRNGSGKSTLLKIVAGLIEPDRG
CCCCCEEHHHHHEEECCHHHHCCHHHEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCC
SRFVQPGATVRYLPQEPDFDGFATTLAYVEAGLAPGDDHYQAAYLLEQLGLHGDENPAHL
CEEECCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
SGGEARRAALARILAPDPDILLLDEPTNHLDLTTIEWLENDLAQRRCAIVMISHDRRFLS
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEEEECCHHHHH
NLSRATAWLDRGVIRQIDRGFSQFESWRDDVLAEEERDQHKLDRKIVMEEHWLRYGVSGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
RKRNVKRLAGLHELRAQRRDYRGPTGAASLAAAEADKSGKLVIEAKSISKAWGDRPIVDA
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEECHHHHHHCCCCCEEE
FSIRINRGDRVGIVGPNGAGKTTLISLLTGALAPDSGTVRLGTNLEIATLDQSRDSLDPK
EEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCEEEEEECCCCCCCCHH
STLSDALTGGRGDQVMVGGKPRHVIGYMKDFLFTQEQARTPLEALSGGERGRLMLARSLA
HHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEHHCC
NPSNLLVLDEPTNDLDLETLDVLEEMLGDYDGTVILISHDRDFLDRVVTSVIAPDGGGKW
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCC
IEYAGGYSDMLAQRGADLSRQPAKAAAAEPAAAKAAPSPATAPAPKRKLSFNEKHALETL
EEECCCHHHHHHHCCCCCCCCCCHHHCCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
PKTIAKLEAEIADLQKQLDDPQLFARDRAKFDKVSAAMAKAHDALHASEHRWLELEMLRE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
EIESA
HHHCC
>Mature Secondary Structure 
APPLIQLKDIALTFGGAALFDGVELAVSAGDRLCLIGRNGSGKSTLLKIVAGLIEPDRG
CCCCEEHHHHHEEECCHHHHCCHHHEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCC
SRFVQPGATVRYLPQEPDFDGFATTLAYVEAGLAPGDDHYQAAYLLEQLGLHGDENPAHL
CEEECCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
SGGEARRAALARILAPDPDILLLDEPTNHLDLTTIEWLENDLAQRRCAIVMISHDRRFLS
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEEEECCHHHHH
NLSRATAWLDRGVIRQIDRGFSQFESWRDDVLAEEERDQHKLDRKIVMEEHWLRYGVSGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
RKRNVKRLAGLHELRAQRRDYRGPTGAASLAAAEADKSGKLVIEAKSISKAWGDRPIVDA
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEECHHHHHHCCCCCEEE
FSIRINRGDRVGIVGPNGAGKTTLISLLTGALAPDSGTVRLGTNLEIATLDQSRDSLDPK
EEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCEEEEEECCCCCCCCHH
STLSDALTGGRGDQVMVGGKPRHVIGYMKDFLFTQEQARTPLEALSGGERGRLMLARSLA
HHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEHHCC
NPSNLLVLDEPTNDLDLETLDVLEEMLGDYDGTVILISHDRDFLDRVVTSVIAPDGGGKW
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCC
IEYAGGYSDMLAQRGADLSRQPAKAAAAEPAAAKAAPSPATAPAPKRKLSFNEKHALETL
EEECCCHHHHHHHCCCCCCCCCCHHHCCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
PKTIAKLEAEIADLQKQLDDPQLFARDRAKFDKVSAAMAKAHDALHASEHRWLELEMLRE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
EIESA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647; 8150261 [H]