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The map label for this gene is fabZ [H]

Identifier: 192290623

GI number: 192290623

Start: 2422681

End: 2423151

Strand: Reverse

Name: fabZ [H]

Synonym: Rpal_2232

Alternate gene names: 192290623

Gene position: 2423151-2422681 (Counterclockwise)

Preceding gene: 192290624

Following gene: 192290622

Centisome position: 42.19

GC content: 61.36

Gene sequence:

>471_bases
ATGAACCTTGAATATTTCCACCTGATCGACCGAATCGCCGAGCTTCGCCTTGCTGACCGCAGCATCACGGTCGAGGCTCG
GGTGCCCGAGACCAGTACGATCTTCGAAGGCCACTTCCCCGGCTACCCGCTGATGCCGGGCGTGCTCTTGATCGAGACCA
TGGCCCAAAGCTCGGGCTGGCTCTTGATCGCGCTGATGCAGTTTCAGCGCATGCCGTTCCTGGCCGCGGTCAAGGAAGCC
AAGATGCGCACCTTCGTGACGCCCGGCGAGACGTTGTCGATCGACGTCTCGGTGGTGCACGAAGGCTCCGGCTTCACGGT
GACCGAAGCGAAGATCAAGAGCGGCGGCAAGCTGGCGTGCAATGCCACGCTGACGTTCCGCCACGTCCCGTTTCCGCATC
CCGATCTGCGCGGGCATATGGAAGCGATGGCGAAGCAAATCGGATTTCCGGAGCAGATGATCCATGGCTGA

Upstream 100 bases:

>100_bases
ACCACCGAGCAGTATTTCGTTCTCAAGAATCTCGCCGCCCGCATCGACGAACTGGTTGCCGCCAAGGGCGCGTAGTGGCG
GTTCGGAAGCCGCCCACGCC

Downstream 100 bases:

>100_bases
CACCACCACGTCCCGCGCCGAACCGATCGAAGCCTGGATTACCGGCATCGGCCTCGCCACCTCGCTGGCCGAGGGGCTCG
ACGCGCATTGGGATGCGCTG

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MNLEYFHLIDRIAELRLADRSITVEARVPETSTIFEGHFPGYPLMPGVLLIETMAQSSGWLLIALMQFQRMPFLAAVKEA
KMRTFVTPGETLSIDVSVVHEGSGFTVTEAKIKSGGKLACNATLTFRHVPFPHPDLRGHMEAMAKQIGFPEQMIHG

Sequences:

>Translated_156_residues
MNLEYFHLIDRIAELRLADRSITVEARVPETSTIFEGHFPGYPLMPGVLLIETMAQSSGWLLIALMQFQRMPFLAAVKEA
KMRTFVTPGETLSIDVSVVHEGSGFTVTEAKIKSGGKLACNATLTFRHVPFPHPDLRGHMEAMAKQIGFPEQMIHG
>Mature_156_residues
MNLEYFHLIDRIAELRLADRSITVEARVPETSTIFEGHFPGYPLMPGVLLIETMAQSSGWLLIALMQFQRMPFLAAVKEA
KMRTFVTPGETLSIDVSVVHEGSGFTVTEAKIKSGGKLACNATLTFRHVPFPHPDLRGHMEAMAKQIGFPEQMIHG

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=122, Percent_Identity=30.327868852459, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 17353; Mature: 17353

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLEYFHLIDRIAELRLADRSITVEARVPETSTIFEGHFPGYPLMPGVLLIETMAQSSGW
CCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCC
LLIALMQFQRMPFLAAVKEAKMRTFVTPGETLSIDVSVVHEGSGFTVTEAKIKSGGKLAC
EEEEEHHHHCCCHHHHHHHHHHHEEECCCCEEEEEEEEEECCCCEEEEEEEECCCCEEEE
NATLTFRHVPFPHPDLRGHMEAMAKQIGFPEQMIHG
EEEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MNLEYFHLIDRIAELRLADRSITVEARVPETSTIFEGHFPGYPLMPGVLLIETMAQSSGW
CCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCC
LLIALMQFQRMPFLAAVKEAKMRTFVTPGETLSIDVSVVHEGSGFTVTEAKIKSGGKLAC
EEEEEHHHHCCCHHHHHHHHHHHEEECCCCEEEEEEEEEECCCCEEEEEEEECCCCEEEE
NATLTFRHVPFPHPDLRGHMEAMAKQIGFPEQMIHG
EEEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA