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The map label for this gene is aaeB [H]

Identifier: 192290555

GI number: 192290555

Start: 2341102

End: 2343114

Strand: Reverse

Name: aaeB [H]

Synonym: Rpal_2164

Alternate gene names: 192290555

Gene position: 2343114-2341102 (Counterclockwise)

Preceding gene: 192290557

Following gene: 192290554

Centisome position: 40.79

GC content: 68.7

Gene sequence:

>2013_bases
ATGTCGCTGCCCGACGAGCAGCAATGGCTGTTTGCGTTCAAGACGTTCGCCGCTGCGATGCTGGCGATGGCGATTGGGCT
GTGGCTCGATCTGCCGCGGCCGTATTGGGCGGTGGCGACGGTCTACATCACCTCGCATCCGCTCTCCGGCACGACGCGGT
CGAAGGCGGTGTTCCGCGTCATCGGCACGCTGATCGGCGCCTGCGTCGCGGTGGCGATCGTGCCCAATCTCGCCGGTGCG
CCGCCGCTGCTGGTGCTCGCCATCGCGCTGTGGTCGGCACTGTGCATCTACGTCTCGGTGCTCGACCGTTCGCCGCGCAG
CTACGTGGCGATGCTGGCAGGCTACACCACCGCGCTGATCGGCTTTCCGACCGTCGATACGCCGAACCAGATCTTCGACA
TCGCGCTGGCGCGAACCGAGGAGATCGTGCTCGGCATCACCTGCGCGGCCGTGGTCTCCAGCGTGGTGTTTCCGCGCTCG
GTCGGCCCGCTCGCGGCGCAGCGGGTCAAGGCGTGGTTCAAGCACGCCCATGCCAGCGTTCGCGACGCCGTCAGCCTGAA
CAAGAGCCCGGCGGCCGAAACCCATCGTCTGCAGGTCGCCGCCGACTCCGCCGACATCGAGAACCTCGTCACCTTCCTCA
GCTACGACACCAATCTCGACCAGAGCGCGACGCGTTGGATCAAGCAATTGCAGCCGCGAATGCTGCTGCTGTTGCCGGTG
ATGTCATCGGTCGCCGATCGCCTCGACGAGCTGCAGCCCCTCGGCGGCCCTTCGGCCCCGGTGGCGGCGTTGGTGGAGCG
CACCCGCGTGTGGATGGAAGGCGACGAGCCCGGCGATGGCGCGGTCCGCGATGCCTTGCTGGCGGACGTTCAGGCCGAGA
TCGACCAGCGCCCGCATTGCGGCGCCTGGCGCGACCTCGTCGAGCTCGGCCTCCTGATGCGGCTTCGGGATCTGCTCAAC
ATCCAGTCCGACTGCATCGCGCTCGCCGCCGCAACCACCGGCAACGCCACGACGCTCGATGCGCCGCTGCACTATCCGAT
CGAACAGCATGTCGCGGTGGTGAAGCATCAGGACCACGGCATGGCGCTGCTCGCCGCCTTCGTCACGCTGTTCACCGTGA
TCACCTGCTGCACCTTCTGGATCGTGTGCGCCTGGCCGGCCGGTGGCACCGCTGCGATGATGGCGACGATCGGTACCAGC
CTGTTCGCGGCGCGCGACGATCCTTATCCGTCGATCGTCGGTCTCACCAAATGGACCATCGTGGCCGCCTTTGCGGCGGC
GGCCTATCTGCTGATGATCCTGCCGGCGGTGCACAATTTCGAGAGTCTGGCGCTGGTACTGGCGCCGGCGTTCATTCTGT
ACGGCGTGCTGATGGGCGCGCCCGCGACCTACCCAATCGGCCTCGGCCTCGCCGTCAACACCGCCAGTCTGATCGCGCTG
CAGGAGATGTACACGTTCGACACCGCAAGCTTCCTGAACTCGACTGTGGCCGTGGTCACCGGCACCGGCCTGGCCGCGCT
GGTCACTGCCGTACTGCGGCCTGTCGGCGCCGAATGGAGCGCGCTGCGCCTGATCAACGCCAACCGCGCCACGCTGGCGC
AGGCCGCCGATATCAGCAGCGAGAACCAGCGCGCCAGCGTCGCGGGACTGATGATCGACCGGATGATGCTGCTGGCGCCG
CGCGCCGCCGCCGCCGGCCACACCATGCCGGAAGCGCTGCGCGAGCTGCGCGCCGGCTTCAACATTCTCGACCTGCACCG
GGCCCGACGTGAGCTGCGGCGCGGCGCTCGTCGCCGGCTGGAACTGCTGCTGATCCGGCTGGAGCGGCACTACGCTTCAG
CTTCATCGGCGCCGCCGGCCGGACTGCTCAGAACGCTCGACCGCGCCCTCGCCGCGGTTCGCGACGAGCCGAGCGCCACC
GCGCGGCGCGCGGTGCTCGGCCTCGTCGGCCTGCGCCGCTGCCTGTTTCCGGCCGCCAAGCCGCCGCAGCTCGCCCCTCA
GGAAGCCGCATGA

Upstream 100 bases:

>100_bases
CCCCATGGTCATTTATGTAAAGGTCGCGTCAGACACCAGCCCTCGTCATCAAGAAGGCCGCGCGCGCACCCTCCTCATTC
GGATCCTGGGATTTCCGCCG

Downstream 100 bases:

>100_bases
TGACTGCTGAACTCAACATCCTCGGCGTGTTCGTGCCGACCATCCTGATCTGCGCCGCCGCGGCCTTCATTCTCACCAGC
CTGGTGTCGCGCCTGCTGGT

Product: fusaric acid resistance protein

Products: NA

Alternate protein names: pHBA efflux pump protein B [H]

Number of amino acids: Translated: 670; Mature: 669

Protein sequence:

>670_residues
MSLPDEQQWLFAFKTFAAAMLAMAIGLWLDLPRPYWAVATVYITSHPLSGTTRSKAVFRVIGTLIGACVAVAIVPNLAGA
PPLLVLAIALWSALCIYVSVLDRSPRSYVAMLAGYTTALIGFPTVDTPNQIFDIALARTEEIVLGITCAAVVSSVVFPRS
VGPLAAQRVKAWFKHAHASVRDAVSLNKSPAAETHRLQVAADSADIENLVTFLSYDTNLDQSATRWIKQLQPRMLLLLPV
MSSVADRLDELQPLGGPSAPVAALVERTRVWMEGDEPGDGAVRDALLADVQAEIDQRPHCGAWRDLVELGLLMRLRDLLN
IQSDCIALAAATTGNATTLDAPLHYPIEQHVAVVKHQDHGMALLAAFVTLFTVITCCTFWIVCAWPAGGTAAMMATIGTS
LFAARDDPYPSIVGLTKWTIVAAFAAAAYLLMILPAVHNFESLALVLAPAFILYGVLMGAPATYPIGLGLAVNTASLIAL
QEMYTFDTASFLNSTVAVVTGTGLAALVTAVLRPVGAEWSALRLINANRATLAQAADISSENQRASVAGLMIDRMMLLAP
RAAAAGHTMPEALRELRAGFNILDLHRARRELRRGARRRLELLLIRLERHYASASSAPPAGLLRTLDRALAAVRDEPSAT
ARRAVLGLVGLRRCLFPAAKPPQLAPQEAA

Sequences:

>Translated_670_residues
MSLPDEQQWLFAFKTFAAAMLAMAIGLWLDLPRPYWAVATVYITSHPLSGTTRSKAVFRVIGTLIGACVAVAIVPNLAGA
PPLLVLAIALWSALCIYVSVLDRSPRSYVAMLAGYTTALIGFPTVDTPNQIFDIALARTEEIVLGITCAAVVSSVVFPRS
VGPLAAQRVKAWFKHAHASVRDAVSLNKSPAAETHRLQVAADSADIENLVTFLSYDTNLDQSATRWIKQLQPRMLLLLPV
MSSVADRLDELQPLGGPSAPVAALVERTRVWMEGDEPGDGAVRDALLADVQAEIDQRPHCGAWRDLVELGLLMRLRDLLN
IQSDCIALAAATTGNATTLDAPLHYPIEQHVAVVKHQDHGMALLAAFVTLFTVITCCTFWIVCAWPAGGTAAMMATIGTS
LFAARDDPYPSIVGLTKWTIVAAFAAAAYLLMILPAVHNFESLALVLAPAFILYGVLMGAPATYPIGLGLAVNTASLIAL
QEMYTFDTASFLNSTVAVVTGTGLAALVTAVLRPVGAEWSALRLINANRATLAQAADISSENQRASVAGLMIDRMMLLAP
RAAAAGHTMPEALRELRAGFNILDLHRARRELRRGARRRLELLLIRLERHYASASSAPPAGLLRTLDRALAAVRDEPSAT
ARRAVLGLVGLRRCLFPAAKPPQLAPQEAA
>Mature_669_residues
SLPDEQQWLFAFKTFAAAMLAMAIGLWLDLPRPYWAVATVYITSHPLSGTTRSKAVFRVIGTLIGACVAVAIVPNLAGAP
PLLVLAIALWSALCIYVSVLDRSPRSYVAMLAGYTTALIGFPTVDTPNQIFDIALARTEEIVLGITCAAVVSSVVFPRSV
GPLAAQRVKAWFKHAHASVRDAVSLNKSPAAETHRLQVAADSADIENLVTFLSYDTNLDQSATRWIKQLQPRMLLLLPVM
SSVADRLDELQPLGGPSAPVAALVERTRVWMEGDEPGDGAVRDALLADVQAEIDQRPHCGAWRDLVELGLLMRLRDLLNI
QSDCIALAAATTGNATTLDAPLHYPIEQHVAVVKHQDHGMALLAAFVTLFTVITCCTFWIVCAWPAGGTAAMMATIGTSL
FAARDDPYPSIVGLTKWTIVAAFAAAAYLLMILPAVHNFESLALVLAPAFILYGVLMGAPATYPIGLGLAVNTASLIALQ
EMYTFDTASFLNSTVAVVTGTGLAALVTAVLRPVGAEWSALRLINANRATLAQAADISSENQRASVAGLMIDRMMLLAPR
AAAAGHTMPEALRELRAGFNILDLHRARRELRRGARRRLELLLIRLERHYASASSAPPAGLLRTLDRALAAVRDEPSATA
RRAVLGLVGLRRCLFPAAKPPQLAPQEAA

Specific function: Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family [H]

Homologues:

Organism=Escherichia coli, GI1787933, Length=532, Percent_Identity=24.812030075188, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1789636, Length=540, Percent_Identity=23.3333333333333, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 71779; Mature: 71647

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPDEQQWLFAFKTFAAAMLAMAIGLWLDLPRPYWAVATVYITSHPLSGTTRSKAVFRV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEEECCCCCCCHHHHHHHHH
IGTLIGACVAVAIVPNLAGAPPLLVLAIALWSALCIYVSVLDRSPRSYVAMLAGYTTALI
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GFPTVDTPNQIFDIALARTEEIVLGITCAAVVSSVVFPRSVGPLAAQRVKAWFKHAHASV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
RDAVSLNKSPAAETHRLQVAADSADIENLVTFLSYDTNLDQSATRWIKQLQPRMLLLLPV
HHHHHCCCCCCCCHHEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHH
MSSVADRLDELQPLGGPSAPVAALVERTRVWMEGDEPGDGAVRDALLADVQAEIDQRPHC
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
GAWRDLVELGLLMRLRDLLNIQSDCIALAAATTGNATTLDAPLHYPIEQHVAVVKHQDHG
CHHHHHHHHHHHHHHHHHHCCHHHHHEEEEECCCCCEEECCCCCCCHHHHHHHHEECCCC
MALLAAFVTLFTVITCCTFWIVCAWPAGGTAAMMATIGTSLFAARDDPYPSIVGLTKWTI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VAAFAAAAYLLMILPAVHNFESLALVLAPAFILYGVLMGAPATYPIGLGLAVNTASLIAL
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHH
QEMYTFDTASFLNSTVAVVTGTGLAALVTAVLRPVGAEWSALRLINANRATLAQAADISS
HHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCHHEEEECCCHHHHHHHHCCCC
ENQRASVAGLMIDRMMLLAPRAAAAGHTMPEALRELRAGFNILDLHRARRELRRGARRRL
CCCHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ELLLIRLERHYASASSAPPAGLLRTLDRALAAVRDEPSATARRAVLGLVGLRRCLFPAAK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
PPQLAPQEAA
CCCCCCCCCC
>Mature Secondary Structure 
SLPDEQQWLFAFKTFAAAMLAMAIGLWLDLPRPYWAVATVYITSHPLSGTTRSKAVFRV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEEECCCCCCCHHHHHHHHH
IGTLIGACVAVAIVPNLAGAPPLLVLAIALWSALCIYVSVLDRSPRSYVAMLAGYTTALI
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GFPTVDTPNQIFDIALARTEEIVLGITCAAVVSSVVFPRSVGPLAAQRVKAWFKHAHASV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
RDAVSLNKSPAAETHRLQVAADSADIENLVTFLSYDTNLDQSATRWIKQLQPRMLLLLPV
HHHHHCCCCCCCCHHEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHH
MSSVADRLDELQPLGGPSAPVAALVERTRVWMEGDEPGDGAVRDALLADVQAEIDQRPHC
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
GAWRDLVELGLLMRLRDLLNIQSDCIALAAATTGNATTLDAPLHYPIEQHVAVVKHQDHG
CHHHHHHHHHHHHHHHHHHCCHHHHHEEEEECCCCCEEECCCCCCCHHHHHHHHEECCCC
MALLAAFVTLFTVITCCTFWIVCAWPAGGTAAMMATIGTSLFAARDDPYPSIVGLTKWTI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VAAFAAAAYLLMILPAVHNFESLALVLAPAFILYGVLMGAPATYPIGLGLAVNTASLIAL
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHH
QEMYTFDTASFLNSTVAVVTGTGLAALVTAVLRPVGAEWSALRLINANRATLAQAADISS
HHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCHHEEEECCCHHHHHHHHCCCC
ENQRASVAGLMIDRMMLLAPRAAAAGHTMPEALRELRAGFNILDLHRARRELRRGARRRL
CCCHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ELLLIRLERHYASASSAPPAGLLRTLDRALAAVRDEPSATARRAVLGLVGLRRCLFPAAK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
PPQLAPQEAA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA