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The map label for this gene is feaR [H]

Identifier: 192290537

GI number: 192290537

Start: 2318997

End: 2320019

Strand: Reverse

Name: feaR [H]

Synonym: Rpal_2146

Alternate gene names: 192290537

Gene position: 2320019-2318997 (Counterclockwise)

Preceding gene: 192290539

Following gene: 192290536

Centisome position: 40.39

GC content: 69.6

Gene sequence:

>1023_bases
ATGGCGTCCCTTCCCCGACTCTATTACGTCACCTCCGGCCTCGACGAGGCCAACGCGTTCGCGACCTGGCGTGCGGTGAT
CTCACCGCTGTTCGAGCCGCGGCCCTGCGGGCCGAGCCGGAAGACGCCGACCGGATCGGCCTACGGCATCATCATCGGCG
ACCTGGTGGTCGCCAAGGTTGCGTTCAACGCCCAGGATTTCGTCCGCGACGCCCAGCGCATCGCGGTGACGCCGGATCAC
CTGCTGCTGCACCTCTACGTGTCCGGCGGCTTCAACGGTGAAGTGACGCGGCAGCAGACCGTGATCGGCCCCGGCAAGGT
GGCGCTGATCGATCTTGCCTGCCCGCTCTCGACCCGCGCGTTCGCGTCGAACACGATGTGCCTGATCGTGCCGCGCAAGC
TGCTCGCGGGGCTGCCGCTGGACGCGCTCAAGCCGAAGCTCGATCCGCTGCGCAACGACCTGCTCGCGGCCTATATCCGC
TCGCTGCAGGAGCGCAGCGCGCAGCTCACCGAGGCCGACGTGGCGACGACGGTGGCGGAGACCGCCGATTTCCTGCGCCG
CCTGCTGGCACCGTCCGCCGAGGCCGACCTCGCCCCTGAGCGCAGCGCCGACGAGACCATTCTGGCGCTGACCGAGGCGC
TGATCCGCGACAACCTCGCGCTGCCGGAACTGTCGCCTGACTGGCTGGCGCAGCAACTCGACGTGTCGCGCGCCTCGCTG
TACCGGCTGTTCGCCGATCGCGGCGGGGTGATGCGTTATGTCCAGGAACGCCGGCTGCTCGCGGTCCAGGCCGCGCTCGC
CGATCCGCTGGAGACGCGGCGGCTGTCGCGCCTCGCTTCCGATCTCGGCTTCAAGAGCGAGGCGCATTTCAGCCGCTCGT
TCCGCGCCCGTTTCGGCATCACCGCCAGCGCCTATCGCAAGGCACAGCTCGATGCCTCGGCCGCGATCCAGCTCACCAGC
CCCGCAGTGGTGCAGCAATGGTGGACCGCTGTCGCGCGCGATCCGCTCCGGCACGCCGGCTGA

Upstream 100 bases:

>100_bases
CGTCTTTCTCGGAAAAAACCGCTAAGCTGAAAGCACTTGGCCGCGGGCGCAGCGAAATACCGATGACCTGATCGAGCCGG
CTTGAAGATCAATCGACCCG

Downstream 100 bases:

>100_bases
ACGAGAACGATTCAAGCGAAGCTCTAGCCTAAAATCCGGCTTGTCCGCGTTCGGAACGGCCGTGTAAGAGCGAACCGACG
ATTGATGCGAGGAGCCCAGC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MASLPRLYYVTSGLDEANAFATWRAVISPLFEPRPCGPSRKTPTGSAYGIIIGDLVVAKVAFNAQDFVRDAQRIAVTPDH
LLLHLYVSGGFNGEVTRQQTVIGPGKVALIDLACPLSTRAFASNTMCLIVPRKLLAGLPLDALKPKLDPLRNDLLAAYIR
SLQERSAQLTEADVATTVAETADFLRRLLAPSAEADLAPERSADETILALTEALIRDNLALPELSPDWLAQQLDVSRASL
YRLFADRGGVMRYVQERRLLAVQAALADPLETRRLSRLASDLGFKSEAHFSRSFRARFGITASAYRKAQLDASAAIQLTS
PAVVQQWWTAVARDPLRHAG

Sequences:

>Translated_340_residues
MASLPRLYYVTSGLDEANAFATWRAVISPLFEPRPCGPSRKTPTGSAYGIIIGDLVVAKVAFNAQDFVRDAQRIAVTPDH
LLLHLYVSGGFNGEVTRQQTVIGPGKVALIDLACPLSTRAFASNTMCLIVPRKLLAGLPLDALKPKLDPLRNDLLAAYIR
SLQERSAQLTEADVATTVAETADFLRRLLAPSAEADLAPERSADETILALTEALIRDNLALPELSPDWLAQQLDVSRASL
YRLFADRGGVMRYVQERRLLAVQAALADPLETRRLSRLASDLGFKSEAHFSRSFRARFGITASAYRKAQLDASAAIQLTS
PAVVQQWWTAVARDPLRHAG
>Mature_339_residues
ASLPRLYYVTSGLDEANAFATWRAVISPLFEPRPCGPSRKTPTGSAYGIIIGDLVVAKVAFNAQDFVRDAQRIAVTPDHL
LLHLYVSGGFNGEVTRQQTVIGPGKVALIDLACPLSTRAFASNTMCLIVPRKLLAGLPLDALKPKLDPLRNDLLAAYIRS
LQERSAQLTEADVATTVAETADFLRRLLAPSAEADLAPERSADETILALTEALIRDNLALPELSPDWLAQQLDVSRASLY
RLFADRGGVMRYVQERRLLAVQAALADPLETRRLSRLASDLGFKSEAHFSRSFRARFGITASAYRKAQLDASAAIQLTSP
AVVQQWWTAVARDPLRHAG

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=307, Percent_Identity=26.3843648208469, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37116; Mature: 36985

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLPRLYYVTSGLDEANAFATWRAVISPLFEPRPCGPSRKTPTGSAYGIIIGDLVVAKV
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AFNAQDFVRDAQRIAVTPDHLLLHLYVSGGFNGEVTRQQTVIGPGKVALIDLACPLSTRA
HCCHHHHHHHHHHEECCCCCEEEEEEEECCCCCCCCCCEEEECCCCEEEEEEECCCCHHH
FASNTMCLIVPRKLLAGLPLDALKPKLDPLRNDLLAAYIRSLQERSAQLTEADVATTVAE
HCCCCEEEEECHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TADFLRRLLAPSAEADLAPERSADETILALTEALIRDNLALPELSPDWLAQQLDVSRASL
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
YRLFADRGGVMRYVQERRLLAVQAALADPLETRRLSRLASDLGFKSEAHFSRSFRARFGI
HHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
TASAYRKAQLDASAAIQLTSPAVVQQWWTAVARDPLRHAG
CHHHHHHHHCCCHHEEEECCHHHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure 
ASLPRLYYVTSGLDEANAFATWRAVISPLFEPRPCGPSRKTPTGSAYGIIIGDLVVAKV
CCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AFNAQDFVRDAQRIAVTPDHLLLHLYVSGGFNGEVTRQQTVIGPGKVALIDLACPLSTRA
HCCHHHHHHHHHHEECCCCCEEEEEEEECCCCCCCCCCEEEECCCCEEEEEEECCCCHHH
FASNTMCLIVPRKLLAGLPLDALKPKLDPLRNDLLAAYIRSLQERSAQLTEADVATTVAE
HCCCCEEEEECHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TADFLRRLLAPSAEADLAPERSADETILALTEALIRDNLALPELSPDWLAQQLDVSRASL
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
YRLFADRGGVMRYVQERRLLAVQAALADPLETRRLSRLASDLGFKSEAHFSRSFRARFGI
HHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
TASAYRKAQLDASAAIQLTSPAVVQQWWTAVARDPLRHAG
CHHHHHHHHCCCHHEEEECCHHHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]