Click here to switch to the map view.

The map label for this gene is pleC [H]

Identifier: 192290539

GI number: 192290539

Start: 2324204

End: 2326513

Strand: Reverse

Name: pleC [H]

Synonym: Rpal_2148

Alternate gene names: 192290539

Gene position: 2326513-2324204 (Counterclockwise)

Preceding gene: 192290540

Following gene: 192290537

Centisome position: 40.5

GC content: 64.46

Gene sequence:

>2310_bases
ATGGCGCGCGTGCAGGCAGCGGACGCCTGCGCTCAATCCGATTCAATCAAAGGATTGGCGCAGTCGATCGCTAAACCCGC
CTATCATCGGCTGTTGAATGCAGAACCGGTGTTGCGGCGCGCGGTGCCTTTGCTGATCATCGCATTTCTGGTCACCATCT
TCTTCGGTGCCGCTGTTCAGATCATCGAGCAGAGCAAGCAGAAGCGCGGTGCGATGAACCGCGACCTCAGCGCGCTCGCC
GATCTGATCGCCGAACGTCTCGAACATATCGGCGTCGTCCGGCTCGACCGCCCCGCCTCGATCGAACGCCTGCAGAATCT
GTTGCCGGGCCTGATCCCGACTTGGGGTATTGCGCCGGGGCGGCACGTCATCGTCACCAGCGCCGATCAGCGAATTCTCG
CGCGCGTGCCGATCGGCACCGAACCGAGCGTCGACAACCGCTTTCTCGAAATCCTGGGCGCAGCGTCGCTGACCAAATCA
GGTCAGCAGAGCAGCATCAGCGAAATCACCCTGCCAGGCGGCGCTTCCGCGCTGGCCACGATGCACGTGGTGAAGTCGCT
GCCCGGTCAGGTCGTCATCATCCAGGAAGACACCGGCTCGCTGCTCCGATCGGACACCGCGCTGCAGGTGACGCTGTCGG
CGACCACCGGCTTCGTGGTGCTGATCCTCGGCTTCGCCTTCCATTGGCAATCGACCCGCGCCCGCGAGGGCGACCTGATC
AACGACGCCGTGCGCAGCCGGATCGACACCGCGCTTAATCGCGGCCGCTGCGGGCTGTGGGACTGGGACCTCAGCCGCGG
CCGGATCTTCTGGTCGCAATCGATGTTCACGATCCTCGGCCTGGAAAGCCGCAACGACCTCCTCACCTTCGGTGAGGTCA
ATGCGCTGGTGAAGGGCGAGGACATCGACCTGTTCGCGATCGCCGACGAACTGATGGCCGGCCGCGTCGATCACATCGAC
CACAGCTTCCAGATGCGTCACGCCCACGGCCACTGGATCTGGCTGCGGATGCGCTGCGAACTGACCCAAGAGGCCGGCGC
AACCGAGAAGCACCTGATCGGCATCGCGGTCGATATCACCGAACAGAAGAGCCTTGCCGAGCGTTCGGTCGAAGCCGATC
TGCGCCTGCGCGACGCGATCGAGACCATCCCGGAAGCCTTCGTGCTGTGGGACGCCGAGAACCGGCTGGTGCTGTGCAAT
TCGCACTTCCAGCGCCTGCACAAATTGCCGGACTCGGCGGTGACGCCCGGCACCTCGTACGAGACCATTCTCGAAGTCGG
CCGGATGCCGCAGCTTCGCACCCGGCTGTGCGACAACGGCGCGGTGATGCCCGGCGCCCGCACCTTCGAGGCGCAGCTCG
ACGACGGCAGCTGGCTGCACATCAGCGAGCGCCGCACCAAGGACGGCGGCTACGTCGCAGTCGGCACCGACATCACCAGG
ATCAAGGCGCACGAACAGAAGCTGGTCGACAACGACCTGCGTCTGCGCGCCACCGTCGCCGATCTCAAGATCACGCAGTC
GAAGCTGGAGAAGCAGGCGCTCGAACTCGCCGATCTCGCCCGCAAATATGCCGACGAAAAACGGCGGGCCGAGGAAGCCA
ATCAGACCAAGTCGAAATTCCTGGCCAATATGAGCCACGAGCTGCGCACGCCACTCAACGCCATCATCGGCTTCTCGGAG
ATCATGGGCAGCGGCATGTTCGGCACGCTGGGCTCGGAGAAGTATCAGGAATACTGCCACGACATCATGACCAGCGGTCA
CTATCTGCTGGAGGTGATCAACGACATTCTCGACATGTCGAAGATCGAAGCCGGACGGATGCGGCTGGAGATGGAGCCGC
TCGATCTCGCCAAGACCATCGGCGAGTCGGTCAAAGTCGTCGCCGGCCGCGCCGAGCATAAGCACCTCGAGCTGCGCTCC
GAGCTGAACGACCAGATTCCGATCGTCGCCGACCGCCGCGCCATCAAACAGATCCTGATCAACCTGCTGTCGAACGCGGT
GAAATTCACCCCCGACGCCGGCCGCGTCACCGTGCGCGGTCACGTCGCCGGCGGCTCGATCGTGCTGATGATCGCCGACA
CCGGCATCGGCATTCCGCCGCAATCGCTGCGCCGTCTCGGCCAGCCGTTCGAGCAGGTCGAGAGCCAGCTTACCAAGAGC
TATCACGGCTCGGGCCTCGGCCTCGCCATCGCCAAGTCGCTGGTCAATCTGCACGGCGGCTCGATGCGTCTGCGCTCCAC
CCTCGGCGCCGGCACCGTCGTGATGGTGAGCCTGCCCCGCACCTGCCAGCAGCGCCCCCTCGCCGCCTGA

Upstream 100 bases:

>100_bases
CTCTCGACAGCCCACTAAAAGTCGATTCAAATCCTAATCATGATTCGAACGGCGCTCGCTGCTCGAACGGGTGCTGACGG
ATACTTGGTGGGGGCCACGT

Downstream 100 bases:

>100_bases
TCTCGTCAGGCTTGGTCTCTTCACCGCTCGGTCTCTTTCACGCCTCGTCTGTCCCGCTGCGCTGGCGTGACTTCGCACTG
AGGAGGGAGATTCCGGGTTC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 769; Mature: 768

Protein sequence:

>769_residues
MARVQAADACAQSDSIKGLAQSIAKPAYHRLLNAEPVLRRAVPLLIIAFLVTIFFGAAVQIIEQSKQKRGAMNRDLSALA
DLIAERLEHIGVVRLDRPASIERLQNLLPGLIPTWGIAPGRHVIVTSADQRILARVPIGTEPSVDNRFLEILGAASLTKS
GQQSSISEITLPGGASALATMHVVKSLPGQVVIIQEDTGSLLRSDTALQVTLSATTGFVVLILGFAFHWQSTRAREGDLI
NDAVRSRIDTALNRGRCGLWDWDLSRGRIFWSQSMFTILGLESRNDLLTFGEVNALVKGEDIDLFAIADELMAGRVDHID
HSFQMRHAHGHWIWLRMRCELTQEAGATEKHLIGIAVDITEQKSLAERSVEADLRLRDAIETIPEAFVLWDAENRLVLCN
SHFQRLHKLPDSAVTPGTSYETILEVGRMPQLRTRLCDNGAVMPGARTFEAQLDDGSWLHISERRTKDGGYVAVGTDITR
IKAHEQKLVDNDLRLRATVADLKITQSKLEKQALELADLARKYADEKRRAEEANQTKSKFLANMSHELRTPLNAIIGFSE
IMGSGMFGTLGSEKYQEYCHDIMTSGHYLLEVINDILDMSKIEAGRMRLEMEPLDLAKTIGESVKVVAGRAEHKHLELRS
ELNDQIPIVADRRAIKQILINLLSNAVKFTPDAGRVTVRGHVAGGSIVLMIADTGIGIPPQSLRRLGQPFEQVESQLTKS
YHGSGLGLAIAKSLVNLHGGSMRLRSTLGAGTVVMVSLPRTCQQRPLAA

Sequences:

>Translated_769_residues
MARVQAADACAQSDSIKGLAQSIAKPAYHRLLNAEPVLRRAVPLLIIAFLVTIFFGAAVQIIEQSKQKRGAMNRDLSALA
DLIAERLEHIGVVRLDRPASIERLQNLLPGLIPTWGIAPGRHVIVTSADQRILARVPIGTEPSVDNRFLEILGAASLTKS
GQQSSISEITLPGGASALATMHVVKSLPGQVVIIQEDTGSLLRSDTALQVTLSATTGFVVLILGFAFHWQSTRAREGDLI
NDAVRSRIDTALNRGRCGLWDWDLSRGRIFWSQSMFTILGLESRNDLLTFGEVNALVKGEDIDLFAIADELMAGRVDHID
HSFQMRHAHGHWIWLRMRCELTQEAGATEKHLIGIAVDITEQKSLAERSVEADLRLRDAIETIPEAFVLWDAENRLVLCN
SHFQRLHKLPDSAVTPGTSYETILEVGRMPQLRTRLCDNGAVMPGARTFEAQLDDGSWLHISERRTKDGGYVAVGTDITR
IKAHEQKLVDNDLRLRATVADLKITQSKLEKQALELADLARKYADEKRRAEEANQTKSKFLANMSHELRTPLNAIIGFSE
IMGSGMFGTLGSEKYQEYCHDIMTSGHYLLEVINDILDMSKIEAGRMRLEMEPLDLAKTIGESVKVVAGRAEHKHLELRS
ELNDQIPIVADRRAIKQILINLLSNAVKFTPDAGRVTVRGHVAGGSIVLMIADTGIGIPPQSLRRLGQPFEQVESQLTKS
YHGSGLGLAIAKSLVNLHGGSMRLRSTLGAGTVVMVSLPRTCQQRPLAA
>Mature_768_residues
ARVQAADACAQSDSIKGLAQSIAKPAYHRLLNAEPVLRRAVPLLIIAFLVTIFFGAAVQIIEQSKQKRGAMNRDLSALAD
LIAERLEHIGVVRLDRPASIERLQNLLPGLIPTWGIAPGRHVIVTSADQRILARVPIGTEPSVDNRFLEILGAASLTKSG
QQSSISEITLPGGASALATMHVVKSLPGQVVIIQEDTGSLLRSDTALQVTLSATTGFVVLILGFAFHWQSTRAREGDLIN
DAVRSRIDTALNRGRCGLWDWDLSRGRIFWSQSMFTILGLESRNDLLTFGEVNALVKGEDIDLFAIADELMAGRVDHIDH
SFQMRHAHGHWIWLRMRCELTQEAGATEKHLIGIAVDITEQKSLAERSVEADLRLRDAIETIPEAFVLWDAENRLVLCNS
HFQRLHKLPDSAVTPGTSYETILEVGRMPQLRTRLCDNGAVMPGARTFEAQLDDGSWLHISERRTKDGGYVAVGTDITRI
KAHEQKLVDNDLRLRATVADLKITQSKLEKQALELADLARKYADEKRRAEEANQTKSKFLANMSHELRTPLNAIIGFSEI
MGSGMFGTLGSEKYQEYCHDIMTSGHYLLEVINDILDMSKIEAGRMRLEMEPLDLAKTIGESVKVVAGRAEHKHLELRSE
LNDQIPIVADRRAIKQILINLLSNAVKFTPDAGRVTVRGHVAGGSIVLMIADTGIGIPPQSLRRLGQPFEQVESQLTKSY
HGSGLGLAIAKSLVNLHGGSMRLRSTLGAGTVVMVSLPRTCQQRPLAA

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=262, Percent_Identity=38.9312977099237, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI87081816, Length=257, Percent_Identity=33.4630350194552, Blast_Score=139, Evalue=9e-34,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=33.8842975206612, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=33.4710743801653, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1788713, Length=258, Percent_Identity=34.1085271317829, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1786912, Length=243, Percent_Identity=28.3950617283951, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786783, Length=250, Percent_Identity=28, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=30.0448430493274, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=26.1818181818182, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1788549, Length=277, Percent_Identity=25.6317689530686, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=26.4227642276423, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=26.6666666666667, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1790861, Length=246, Percent_Identity=26.0162601626016, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1788279, Length=226, Percent_Identity=25.6637168141593, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790346, Length=225, Percent_Identity=24, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84590; Mature: 84458

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVQAADACAQSDSIKGLAQSIAKPAYHRLLNAEPVLRRAVPLLIIAFLVTIFFGAAVQ
CCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IIEQSKQKRGAMNRDLSALADLIAERLEHIGVVRLDRPASIERLQNLLPGLIPTWGIAPG
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHCCCCCCCCCCCCC
RHVIVTSADQRILARVPIGTEPSVDNRFLEILGAASLTKSGQQSSISEITLPGGASALAT
CEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHH
MHVVKSLPGQVVIIQEDTGSLLRSDTALQVTLSATTGFVVLILGFAFHWQSTRAREGDLI
HHHHHHCCCCEEEEECCCCHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCHH
NDAVRSRIDTALNRGRCGLWDWDLSRGRIFWSQSMFTILGLESRNDLLTFGEVNALVKGE
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEEEEECCCCCEEEECCCCEEEECC
DIDLFAIADELMAGRVDHIDHSFQMRHAHGHWIWLRMRCELTQEAGATEKHLIGIAVDIT
CCEEHHHHHHHHHCCHHHCCCCCEEEECCCCEEEEEEEEEEHHHCCCCCCEEEEEEEEEC
EQKSLAERSVEADLRLRDAIETIPEAFVLWDAENRLVLCNSHFQRLHKLPDSAVTPGTSY
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECHHHHHHHHCCCCCCCCCCCH
ETILEVGRMPQLRTRLCDNGAVMPGARTFEAQLDDGSWLHISERRTKDGGYVAVGTDITR
HHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCEEEECCCHHH
IKAHEQKLVDNDLRLRATVADLKITQSKLEKQALELADLARKYADEKRRAEEANQTKSKF
HHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANMSHELRTPLNAIIGFSEIMGSGMFGTLGSEKYQEYCHDIMTSGHYLLEVINDILDMS
HHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KIEAGRMRLEMEPLDLAKTIGESVKVVAGRAEHKHLELRSELNDQIPIVADRRAIKQILI
HCCCCCEEEECCHHHHHHHHCCHHEEHCCCCHHHHHHHHHHCCCCCCEEECHHHHHHHHH
NLLSNAVKFTPDAGRVTVRGHVAGGSIVLMIADTGIGIPPQSLRRLGQPFEQVESQLTKS
HHHHHHEEECCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHH
YHGSGLGLAIAKSLVNLHGGSMRLRSTLGAGTVVMVSLPRTCQQRPLAA
HCCCCHHHHHHHHHHHHCCCCEEEHHHCCCCEEEEEECCHHHCCCCCCC
>Mature Secondary Structure 
ARVQAADACAQSDSIKGLAQSIAKPAYHRLLNAEPVLRRAVPLLIIAFLVTIFFGAAVQ
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IIEQSKQKRGAMNRDLSALADLIAERLEHIGVVRLDRPASIERLQNLLPGLIPTWGIAPG
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHCCCCCCCCCCCCC
RHVIVTSADQRILARVPIGTEPSVDNRFLEILGAASLTKSGQQSSISEITLPGGASALAT
CEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHH
MHVVKSLPGQVVIIQEDTGSLLRSDTALQVTLSATTGFVVLILGFAFHWQSTRAREGDLI
HHHHHHCCCCEEEEECCCCHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCHH
NDAVRSRIDTALNRGRCGLWDWDLSRGRIFWSQSMFTILGLESRNDLLTFGEVNALVKGE
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEEEEECCCCCEEEECCCCEEEECC
DIDLFAIADELMAGRVDHIDHSFQMRHAHGHWIWLRMRCELTQEAGATEKHLIGIAVDIT
CCEEHHHHHHHHHCCHHHCCCCCEEEECCCCEEEEEEEEEEHHHCCCCCCEEEEEEEEEC
EQKSLAERSVEADLRLRDAIETIPEAFVLWDAENRLVLCNSHFQRLHKLPDSAVTPGTSY
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECHHHHHHHHCCCCCCCCCCCH
ETILEVGRMPQLRTRLCDNGAVMPGARTFEAQLDDGSWLHISERRTKDGGYVAVGTDITR
HHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCEEEECCCHHH
IKAHEQKLVDNDLRLRATVADLKITQSKLEKQALELADLARKYADEKRRAEEANQTKSKF
HHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANMSHELRTPLNAIIGFSEIMGSGMFGTLGSEKYQEYCHDIMTSGHYLLEVINDILDMS
HHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KIEAGRMRLEMEPLDLAKTIGESVKVVAGRAEHKHLELRSELNDQIPIVADRRAIKQILI
HCCCCCEEEECCHHHHHHHHCCHHEEHCCCCHHHHHHHHHHCCCCCCEEECHHHHHHHHH
NLLSNAVKFTPDAGRVTVRGHVAGGSIVLMIADTGIGIPPQSLRRLGQPFEQVESQLTKS
HHHHHHEEECCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHH
YHGSGLGLAIAKSLVNLHGGSMRLRSTLGAGTVVMVSLPRTCQQRPLAA
HCCCCHHHHHHHHHHHHCCCCEEEHHHCCCCEEEEEECCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]