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The map label for this gene is pcp [H]

Identifier: 192290425

GI number: 192290425

Start: 2205195

End: 2205845

Strand: Reverse

Name: pcp [H]

Synonym: Rpal_2032

Alternate gene names: 192290425

Gene position: 2205845-2205195 (Counterclockwise)

Preceding gene: 192290426

Following gene: 192290424

Centisome position: 38.4

GC content: 68.51

Gene sequence:

>651_bases
GTGAGTGGCCTGCGCATCCTGATCACCGGCTTCGGGCCGTTTCCCGGAGCGCCTTACAATCCGACTCCGCAATTGGTCGA
TCGCCTCGTCAAGCTGCGGAGGCCGGCATTCGACGACGTGGTTCGCGTCGGGCATATCTTCAACGTCAGCTACCGTGCGG
TCGATCGCGACCTGCCGGCGTTGCTGGCGCAGCACCGTCCCGATGCGCTGCTGATGTTCGGCTTGGCAGCCTCAACCCGT
CACGTTCGGATCGAGACGCGCGCCCGCAACGCCATCACCACGCTGTGGCCCGACGCCGAAAAGGTGACGCTGCGTCACGG
CCAGATCGCACCGGGCGAAGACGCGCGTACGTTCGGCGCCCATGGCGCGCGGCTGGCCCGCGCCGCACGGCTCACCGGGA
TCGATGCGCGACTGTCACGCGACGCGGGTCGCTATCTGTGCAATTATCTCTGCTGGCGTGGGATCGAAGCGACGCAGGTG
CAGAGCGGGCCCCGCCTCGCCGCCTTCGTCCACGTGCCGCTCATCAGCCGCGACGGCACCGCCTGGCCGGGAAGCCGCAT
CACCACCGAGCAGTTGGTCGATGCCGGCGAAGCGATGCTGCTGGAGCTGGTGCGGCTGACCCGGCAGACCCGCCGGGTAG
CGGCCGCTTGA

Upstream 100 bases:

>100_bases
ACCCGGCGATCCGCGCCAAGGTGAAATCGACCGAGGCCGCCGTCGCCGAAGGCTCGATCACGCCCACGCTCGGCGCCGAT
CGGGTCGCGGAGCTGATCGG

Downstream 100 bases:

>100_bases
GATCGCATCGCTCAGGAAAGAACCCCGTGGTGCTGCCCGGCGTTGTCCTCTTCCGAGGAGGAACCGATGCCGTACGCGCT
GTTTTGCGACGATGCCAGGG

Product: peptidase C15 pyroglutamyl peptidase I

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSGLRILITGFGPFPGAPYNPTPQLVDRLVKLRRPAFDDVVRVGHIFNVSYRAVDRDLPALLAQHRPDALLMFGLAASTR
HVRIETRARNAITTLWPDAEKVTLRHGQIAPGEDARTFGAHGARLARAARLTGIDARLSRDAGRYLCNYLCWRGIEATQV
QSGPRLAAFVHVPLISRDGTAWPGSRITTEQLVDAGEAMLLELVRLTRQTRRVAAA

Sequences:

>Translated_216_residues
MSGLRILITGFGPFPGAPYNPTPQLVDRLVKLRRPAFDDVVRVGHIFNVSYRAVDRDLPALLAQHRPDALLMFGLAASTR
HVRIETRARNAITTLWPDAEKVTLRHGQIAPGEDARTFGAHGARLARAARLTGIDARLSRDAGRYLCNYLCWRGIEATQV
QSGPRLAAFVHVPLISRDGTAWPGSRITTEQLVDAGEAMLLELVRLTRQTRRVAAA
>Mature_215_residues
SGLRILITGFGPFPGAPYNPTPQLVDRLVKLRRPAFDDVVRVGHIFNVSYRAVDRDLPALLAQHRPDALLMFGLAASTRH
VRIETRARNAITTLWPDAEKVTLRHGQIAPGEDARTFGAHGARLARAARLTGIDARLSRDAGRYLCNYLCWRGIEATQVQ
SGPRLAAFVHVPLISRDGTAWPGSRITTEQLVDAGEAMLLELVRLTRQTRRVAAA

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 23818; Mature: 23687

Theoretical pI: Translated: 11.49; Mature: 11.49

Prosite motif: PS01334 PYRASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLRILITGFGPFPGAPYNPTPQLVDRLVKLRRPAFDDVVRVGHIFNVSYRAVDRDLPA
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHH
LLAQHRPDALLMFGLAASTRHVRIETRARNAITTLWPDAEKVTLRHGQIAPGEDARTFGA
HHHHCCCCEEEEEEECCCCEEEEEEECCCCCEEEECCCCCEEEEECCCCCCCCCCCHHCC
HGARLARAARLTGIDARLSRDAGRYLCNYLCWRGIEATQVQSGPRLAAFVHVPLISRDGT
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEEEEECCCCC
AWPGSRITTEQLVDAGEAMLLELVRLTRQTRRVAAA
CCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGLRILITGFGPFPGAPYNPTPQLVDRLVKLRRPAFDDVVRVGHIFNVSYRAVDRDLPA
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHH
LLAQHRPDALLMFGLAASTRHVRIETRARNAITTLWPDAEKVTLRHGQIAPGEDARTFGA
HHHHCCCCEEEEEEECCCCEEEEEEECCCCCEEEECCCCCEEEEECCCCCCCCCCCHHCC
HGARLARAARLTGIDARLSRDAGRYLCNYLCWRGIEATQVQSGPRLAAFVHVPLISRDGT
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEEEEECCCCC
AWPGSRITTEQLVDAGEAMLLELVRLTRQTRRVAAA
CCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]