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The map label for this gene is ptrB [H]

Identifier: 192290156

GI number: 192290156

Start: 1887378

End: 1889495

Strand: Reverse

Name: ptrB [H]

Synonym: Rpal_1758

Alternate gene names: 192290156

Gene position: 1889495-1887378 (Counterclockwise)

Preceding gene: 192290162

Following gene: 192290155

Centisome position: 32.89

GC content: 66.24

Gene sequence:

>2118_bases
ATGACCTCTGCCCCGCCCCGTGCCGCCAACCAGCAACCGCCGGTCGCGCCGCGCCGTCCGCATGAATTCACCACCCACGG
CATCACGCTGACCGACGACTATGCCTGGCTGAAGGATCCGAACTGGCAGGAGGTGCTGCGCGATCCGTCGCTGCTCGATC
CCGATATCCGCACCTATCTCGAAGACGAGAACGGCTACACCGACAGCGTGCTTGGCCACACCACGAGTTTGCAGAAGAAG
CTGGTCGCCGAGATGCGCGGGAGGATCAAGGAGGACGATTCCAGCGTCCCCTCGCCGGATGGTCCTTACGCTTACTTGCG
CAAATATCGCGAGGGCGGCCAGCACCCGCTGTACGGCCGCGTCGCGCGCGACGGCAGCGGCGAGATCGACATCGTCCTCG
ACGGTGACGAGCTTGCCAAGGGCCACGACTACTTCCAGTTCGGCGACCGTCGGCACTCGCTCGACCACAAGCTGGAAGGC
TGGAGCGCCGACACCAAGGGCTCCGAATACTACACCATCCGCGTCCGCGACTGGACGACCAAGCAGGACCTGCCCGACGT
GGTCGAGGAGACCGACGGCGGCCTGGTGTGGACCGCGGATTCGACCGCATTCTTCTACGTCAAGCTCGACGACAACCACC
GCCCGATGCAGGTGTGGCTGCACAAGCTCGGCACCCAGCAGGCCGACGATCTTCTGATCTACGAAGAGCCGGACTCCGGC
TGGTTCACCCACATCCACGAGAGCACCAGCGGCCGGTTCTGCGTCATCGCCGGCGGCGATCACGAGACCTCCGAGCAGCG
GCTGATCGATGTCTCCGACCCGACCGCGCCGCCGCGCCTCGTCGCCAAGCGTGAACTCGGCGTGCAATATTCGCTCGGCG
ATCGCGGCGACGAATTGTTCATCCTCACCAATGCCGACGGTGCGATCGACTTCAAGATCGTCACCGCGCCGCTGGCTGAG
CCGACCCGCAACAACTGGCGCGATTTGATTCCGCACCGCGCCGGGATCTATGTGATCGATTTCGATCTCACGACCGGCCA
TCTGATCCGGCTGGAGCGCGCCAATGCGCTGCCCTCGATCACCATCCGCGACCTGAAGACCGGCGACGAGCACGCCATCG
CGTTCGCCGAGACCGCATATTCGCTCGGCACCATCGGCGGCTACGAGTTCGACACCACGAACCTGCGGTTCTCGTATTCG
TCGATGACGACGCCGTCGGAAGTCTATGACTACGACATGGCGACGCGGCAGCGGACCTTGCGCAAGCGCCAGGAAATTCC
CTCCGGCCACAATCCGGCCGACTACGTCACCACCCGGATCATGGCGAAGGCCGGCGACGGCGCCGAGGTGCCGGTGTCGA
TCCTGCATCGGGCCGGCCTCAAGCTCGACGGCCAGGCGCCGCTGCTGCTGTATGGCTACGGCTCCTACGGCCATGCAATG
GGCGCCGGCTTTTCGGCCAACGCACTGTCGCTGGTCGACCGCGGCTTCGTCTATGCGATCGCCCACATCCGCGGCGGCGC
CGACAAGGGCTGGGGCTGGTATCTGGACGGCAAGCGCGAGAAGAAGACCAACTCGTTCGACGATTTCGCCGCCAGCGCCC
GCGCGCTGATTGCGGCGAACTACACCTCGCCCAAGCGCATCGTCGCCCACGGCGGCAGCGCCGGCGGCATGCTGATGGGC
GCCGTCGCCAATCGCGCCGGTGAGCTGTTCGCCGGCATCGTCGCCGAGGTGCCGTTCGTCGACGTGCTCAACACCATGCT
GGACGACACCCTGCCGCTGACCCCTCCCGAGTGGCCGGAGTGGGGCAATCCGATTGCGAGCGAAGCCGACTTCAAGACCA
TCCTGTCGTATTCGCCCTACGACAACGTCGCGGCCAAGGAGTATCCGGCGATCCTGGCGATGGGCGGCCTCACCGATCCG
CGCGTCACCTATTGGGAGCCGGCCAAATGGGTCGCGCGGCTGCGCGCCACCATGACCGGCGGCGGCCCGGTGCTGCTCCG
TATCAACATGGGCGCCGGCCACGGCGGCGCCTCCGGCCGCTTCAGCCGCCTCGACGAGATCGCGATCGTCTATGCGTTCG
CGCTGTGGGCGGTTGGCCTGGCTGACGCCACCGCGTGA

Upstream 100 bases:

>100_bases
CACCGGAACCGGCGCCCCTGCCTATCCAGCGCAATCCGCCCGGCGCCGCAAGGCGGAAACGTGCTAAGCCTGCCTGCCCC
ACCCTGAACGAGACCTGCCG

Downstream 100 bases:

>100_bases
GCGTGGCATAAAGTCTTGGACACCGCCCTCTCCCCGTCATTGCGAGCGAAGCAATCCAGAAGCGCCGAGCACTGAGCCTG
ATTGCTTCGTCGCTCCGCTC

Product: Oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 705; Mature: 704

Protein sequence:

>705_residues
MTSAPPRAANQQPPVAPRRPHEFTTHGITLTDDYAWLKDPNWQEVLRDPSLLDPDIRTYLEDENGYTDSVLGHTTSLQKK
LVAEMRGRIKEDDSSVPSPDGPYAYLRKYREGGQHPLYGRVARDGSGEIDIVLDGDELAKGHDYFQFGDRRHSLDHKLEG
WSADTKGSEYYTIRVRDWTTKQDLPDVVEETDGGLVWTADSTAFFYVKLDDNHRPMQVWLHKLGTQQADDLLIYEEPDSG
WFTHIHESTSGRFCVIAGGDHETSEQRLIDVSDPTAPPRLVAKRELGVQYSLGDRGDELFILTNADGAIDFKIVTAPLAE
PTRNNWRDLIPHRAGIYVIDFDLTTGHLIRLERANALPSITIRDLKTGDEHAIAFAETAYSLGTIGGYEFDTTNLRFSYS
SMTTPSEVYDYDMATRQRTLRKRQEIPSGHNPADYVTTRIMAKAGDGAEVPVSILHRAGLKLDGQAPLLLYGYGSYGHAM
GAGFSANALSLVDRGFVYAIAHIRGGADKGWGWYLDGKREKKTNSFDDFAASARALIAANYTSPKRIVAHGGSAGGMLMG
AVANRAGELFAGIVAEVPFVDVLNTMLDDTLPLTPPEWPEWGNPIASEADFKTILSYSPYDNVAAKEYPAILAMGGLTDP
RVTYWEPAKWVARLRATMTGGGPVLLRINMGAGHGGASGRFSRLDEIAIVYAFALWAVGLADATA

Sequences:

>Translated_705_residues
MTSAPPRAANQQPPVAPRRPHEFTTHGITLTDDYAWLKDPNWQEVLRDPSLLDPDIRTYLEDENGYTDSVLGHTTSLQKK
LVAEMRGRIKEDDSSVPSPDGPYAYLRKYREGGQHPLYGRVARDGSGEIDIVLDGDELAKGHDYFQFGDRRHSLDHKLEG
WSADTKGSEYYTIRVRDWTTKQDLPDVVEETDGGLVWTADSTAFFYVKLDDNHRPMQVWLHKLGTQQADDLLIYEEPDSG
WFTHIHESTSGRFCVIAGGDHETSEQRLIDVSDPTAPPRLVAKRELGVQYSLGDRGDELFILTNADGAIDFKIVTAPLAE
PTRNNWRDLIPHRAGIYVIDFDLTTGHLIRLERANALPSITIRDLKTGDEHAIAFAETAYSLGTIGGYEFDTTNLRFSYS
SMTTPSEVYDYDMATRQRTLRKRQEIPSGHNPADYVTTRIMAKAGDGAEVPVSILHRAGLKLDGQAPLLLYGYGSYGHAM
GAGFSANALSLVDRGFVYAIAHIRGGADKGWGWYLDGKREKKTNSFDDFAASARALIAANYTSPKRIVAHGGSAGGMLMG
AVANRAGELFAGIVAEVPFVDVLNTMLDDTLPLTPPEWPEWGNPIASEADFKTILSYSPYDNVAAKEYPAILAMGGLTDP
RVTYWEPAKWVARLRATMTGGGPVLLRINMGAGHGGASGRFSRLDEIAIVYAFALWAVGLADATA
>Mature_704_residues
TSAPPRAANQQPPVAPRRPHEFTTHGITLTDDYAWLKDPNWQEVLRDPSLLDPDIRTYLEDENGYTDSVLGHTTSLQKKL
VAEMRGRIKEDDSSVPSPDGPYAYLRKYREGGQHPLYGRVARDGSGEIDIVLDGDELAKGHDYFQFGDRRHSLDHKLEGW
SADTKGSEYYTIRVRDWTTKQDLPDVVEETDGGLVWTADSTAFFYVKLDDNHRPMQVWLHKLGTQQADDLLIYEEPDSGW
FTHIHESTSGRFCVIAGGDHETSEQRLIDVSDPTAPPRLVAKRELGVQYSLGDRGDELFILTNADGAIDFKIVTAPLAEP
TRNNWRDLIPHRAGIYVIDFDLTTGHLIRLERANALPSITIRDLKTGDEHAIAFAETAYSLGTIGGYEFDTTNLRFSYSS
MTTPSEVYDYDMATRQRTLRKRQEIPSGHNPADYVTTRIMAKAGDGAEVPVSILHRAGLKLDGQAPLLLYGYGSYGHAMG
AGFSANALSLVDRGFVYAIAHIRGGADKGWGWYLDGKREKKTNSFDDFAASARALIAANYTSPKRIVAHGGSAGGMLMGA
VANRAGELFAGIVAEVPFVDVLNTMLDDTLPLTPPEWPEWGNPIASEADFKTILSYSPYDNVAAKEYPAILAMGGLTDPR
VTYWEPAKWVARLRATMTGGGPVLLRINMGAGHGGASGRFSRLDEIAIVYAFALWAVGLADATA

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI284172420, Length=530, Percent_Identity=30.188679245283, Blast_Score=213, Evalue=5e-55,
Organism=Homo sapiens, GI284172413, Length=530, Percent_Identity=30.188679245283, Blast_Score=213, Evalue=5e-55,
Organism=Homo sapiens, GI70778815, Length=530, Percent_Identity=30.188679245283, Blast_Score=213, Evalue=5e-55,
Organism=Homo sapiens, GI284172438, Length=530, Percent_Identity=30.188679245283, Blast_Score=212, Evalue=8e-55,
Organism=Homo sapiens, GI284172431, Length=530, Percent_Identity=30.188679245283, Blast_Score=212, Evalue=8e-55,
Organism=Homo sapiens, GI41349456, Length=717, Percent_Identity=25.6624825662483, Blast_Score=210, Evalue=4e-54,
Organism=Homo sapiens, GI108860686, Length=313, Percent_Identity=33.2268370607029, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI108860692, Length=239, Percent_Identity=36.4016736401674, Blast_Score=139, Evalue=7e-33,
Organism=Escherichia coli, GI1788150, Length=694, Percent_Identity=38.6167146974063, Blast_Score=454, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24583414, Length=709, Percent_Identity=25.8110014104372, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI221510989, Length=715, Percent_Identity=24.0559440559441, Blast_Score=182, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 77690; Mature: 77558

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAPPRAANQQPPVAPRRPHEFTTHGITLTDDYAWLKDPNWQEVLRDPSLLDPDIRTYL
CCCCCCCCCCCCCCCCCCCCCCEEECCEEEECCCCCCCCCCHHHHHCCCCCCCCHHHHHC
EDENGYTDSVLGHTTSLQKKLVAEMRGRIKEDDSSVPSPDGPYAYLRKYREGGQHPLYGR
CCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEE
VARDGSGEIDIVLDGDELAKGHDYFQFGDRRHSLDHKLEGWSADTKGSEYYTIRVRDWTT
EECCCCCCEEEEECCHHHCCCCCHHHCCCCHHCCHHCCCCCCCCCCCCEEEEEEEECCCC
KQDLPDVVEETDGGLVWTADSTAFFYVKLDDNHRPMQVWLHKLGTQQADDLLIYEEPDSG
CCCCHHHHHHCCCCEEEEECCCEEEEEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCCC
WFTHIHESTSGRFCVIAGGDHETSEQRLIDVSDPTAPPRLVAKRELGVQYSLGDRGDELF
CEEEEEECCCCCEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHCCEEEECCCCCCEEE
ILTNADGAIDFKIVTAPLAEPTRNNWRDLIPHRAGIYVIDFDLTTGHLIRLERANALPSI
EEECCCCEEEEEEEECCCCCCCCCCHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCE
TIRDLKTGDEHAIAFAETAYSLGTIGGYEFDTTNLRFSYSSMTTPSEVYDYDMATRQRTL
EEEECCCCCCCEEEEHHHHHHHCCCCCCEECCCEEEEEECCCCCCHHHHHHHHHHHHHHH
RKRQEIPSGHNPADYVTTRIMAKAGDGAEVPVSILHRAGLKLDGQAPLLLYGYGSYGHAM
HHHHCCCCCCCCHHHHHHHHHEECCCCCCCHHHHHHHCCCEECCCCCEEEEECCCCCHHH
GAGFSANALSLVDRGFVYAIAHIRGGADKGWGWYLDGKREKKTNSFDDFAASARALIAAN
CCCCCCCHHHHHHCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHCEEEEEEC
YTSPKRIVAHGGSAGGMLMGAVANRAGELFAGIVAEVPFVDVLNTMLDDTLPLTPPEWPE
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCC
WGNPIASEADFKTILSYSPYDNVAAKEYPAILAMGGLTDPRVTYWEPAKWVARLRATMTG
CCCCCCCCCCHHHHEECCCCCCCCHHHCCEEEEECCCCCCCEEEECHHHHHHHHHHHCCC
GGPVLLRINMGAGHGGASGRFSRLDEIAIVYAFALWAVGLADATA
CCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSAPPRAANQQPPVAPRRPHEFTTHGITLTDDYAWLKDPNWQEVLRDPSLLDPDIRTYL
CCCCCCCCCCCCCCCCCCCCCEEECCEEEECCCCCCCCCCHHHHHCCCCCCCCHHHHHC
EDENGYTDSVLGHTTSLQKKLVAEMRGRIKEDDSSVPSPDGPYAYLRKYREGGQHPLYGR
CCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEE
VARDGSGEIDIVLDGDELAKGHDYFQFGDRRHSLDHKLEGWSADTKGSEYYTIRVRDWTT
EECCCCCCEEEEECCHHHCCCCCHHHCCCCHHCCHHCCCCCCCCCCCCEEEEEEEECCCC
KQDLPDVVEETDGGLVWTADSTAFFYVKLDDNHRPMQVWLHKLGTQQADDLLIYEEPDSG
CCCCHHHHHHCCCCEEEEECCCEEEEEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCCC
WFTHIHESTSGRFCVIAGGDHETSEQRLIDVSDPTAPPRLVAKRELGVQYSLGDRGDELF
CEEEEEECCCCCEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHCCEEEECCCCCCEEE
ILTNADGAIDFKIVTAPLAEPTRNNWRDLIPHRAGIYVIDFDLTTGHLIRLERANALPSI
EEECCCCEEEEEEEECCCCCCCCCCHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCE
TIRDLKTGDEHAIAFAETAYSLGTIGGYEFDTTNLRFSYSSMTTPSEVYDYDMATRQRTL
EEEECCCCCCCEEEEHHHHHHHCCCCCCEECCCEEEEEECCCCCCHHHHHHHHHHHHHHH
RKRQEIPSGHNPADYVTTRIMAKAGDGAEVPVSILHRAGLKLDGQAPLLLYGYGSYGHAM
HHHHCCCCCCCCHHHHHHHHHEECCCCCCCHHHHHHHCCCEECCCCCEEEEECCCCCHHH
GAGFSANALSLVDRGFVYAIAHIRGGADKGWGWYLDGKREKKTNSFDDFAASARALIAAN
CCCCCCCHHHHHHCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHCEEEEEEC
YTSPKRIVAHGGSAGGMLMGAVANRAGELFAGIVAEVPFVDVLNTMLDDTLPLTPPEWPE
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCC
WGNPIASEADFKTILSYSPYDNVAAKEYPAILAMGGLTDPRVTYWEPAKWVARLRATMTG
CCCCCCCCCCHHHHEECCCCCCCCHHHCCEEEEECCCCCCCEEEECHHHHHHHHHHHCCC
GGPVLLRINMGAGHGGASGRFSRLDEIAIVYAFALWAVGLADATA
CCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]