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The map label for this gene is degU [H]

Identifier: 192290074

GI number: 192290074

Start: 1795639

End: 1796325

Strand: Reverse

Name: degU [H]

Synonym: Rpal_1676

Alternate gene names: 192290074

Gene position: 1796325-1795639 (Counterclockwise)

Preceding gene: 192290075

Following gene: 192290073

Centisome position: 31.27

GC content: 65.79

Gene sequence:

>687_bases
ATGAAAGCAACCGCGATGGACCAGCAATCCCCTTCCCGACTGCGGGTGTTTATCGCCGACGATCACCCGGTGGTGCTCAG
CGGCATGAAGGCGCTGGTCGCAGGCGATCCCGGGCTCGAAGTGGTGGGCGAGGCCAGCGACGGTCCGAACGCCTTGCGCC
GCGCCACGGAATTGAAGCCGGACGTCGCCGTGCTCGATCTGTCGATGCCCGGCCTCAACGGCATCGAGGTGGCGCGCAAG
TTCCTCGCCGCCTGTCCGGACTGCCGCGTGCTGGTGCTGACCGTGCACGAAGACGGCGCTTACTTGCGGCAATTGCTCGA
TCTCGGCGTCGCCGGCTACGTGCTGAAACGCTCCGCCACCGAAGAACTGATCCGCGGCATCCACGCGGTCGGCAGCGGCG
GCATCTATCTCGATCCGGCGATCGCCGGCCGCGCCATCGGACGCACCACGCCGCATCTGCACAATGGCGACGAGCACAAT
GCGGTGTCGGAACTGTCGACGCGCGAGATCGAGGTGCTGCGGCTCGCCGCGATCGGCCATAGTAATAAGACCATCGCCGC
CAAGCTGCAGATCGGCGCCAAGAGCGTCGAAACCTACAAGGCGCGCGGCATGGCAAAGCTCGGCTTCCACAATCGCGTCG
AGGTGGTGCGGTTCGCACTCAGCATGGGCTGGCTGTCGGACCCATAG

Upstream 100 bases:

>100_bases
GGCATCCGTGAGCGGCTGTCGCTGGTCGGCGGCTCGCTCGAAATCGAATCCGCGCCCGGCAAGGGCACTGCGCTGTACGC
GCGCATTCCGCTGTGACCAG

Downstream 100 bases:

>100_bases
CGTCCGTACCATTTCGCCCCGTTGATCCGGTCCGATCGACCCGCTAGCCTGCACCTTCATTGGGCAAGCAACTTCCCGCG
GGCACTGGTGCTTTACGCGC

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKATAMDQQSPSRLRVFIADDHPVVLSGMKALVAGDPGLEVVGEASDGPNALRRATELKPDVAVLDLSMPGLNGIEVARK
FLAACPDCRVLVLTVHEDGAYLRQLLDLGVAGYVLKRSATEELIRGIHAVGSGGIYLDPAIAGRAIGRTTPHLHNGDEHN
AVSELSTREIEVLRLAAIGHSNKTIAAKLQIGAKSVETYKARGMAKLGFHNRVEVVRFALSMGWLSDP

Sequences:

>Translated_228_residues
MKATAMDQQSPSRLRVFIADDHPVVLSGMKALVAGDPGLEVVGEASDGPNALRRATELKPDVAVLDLSMPGLNGIEVARK
FLAACPDCRVLVLTVHEDGAYLRQLLDLGVAGYVLKRSATEELIRGIHAVGSGGIYLDPAIAGRAIGRTTPHLHNGDEHN
AVSELSTREIEVLRLAAIGHSNKTIAAKLQIGAKSVETYKARGMAKLGFHNRVEVVRFALSMGWLSDP
>Mature_228_residues
MKATAMDQQSPSRLRVFIADDHPVVLSGMKALVAGDPGLEVVGEASDGPNALRRATELKPDVAVLDLSMPGLNGIEVARK
FLAACPDCRVLVLTVHEDGAYLRQLLDLGVAGYVLKRSATEELIRGIHAVGSGGIYLDPAIAGRAIGRTTPHLHNGDEHN
AVSELSTREIEVLRLAAIGHSNKTIAAKLQIGAKSVETYKARGMAKLGFHNRVEVVRFALSMGWLSDP

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=211, Percent_Identity=30.8056872037915, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788712, Length=206, Percent_Identity=29.6116504854369, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790102, Length=213, Percent_Identity=35.2112676056338, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788521, Length=204, Percent_Identity=33.8235294117647, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1788546, Length=210, Percent_Identity=31.9047619047619, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787473, Length=209, Percent_Identity=31.5789473684211, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1786747, Length=204, Percent_Identity=25, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24329; Mature: 24329

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKATAMDQQSPSRLRVFIADDHPVVLSGMKALVAGDPGLEVVGEASDGPNALRRATELKP
CCCCCCCCCCCCEEEEEEECCCCEEHHCCHHEECCCCCCEEEECCCCCHHHHHHHHHCCC
DVAVLDLSMPGLNGIEVARKFLAACPDCRVLVLTVHEDGAYLRQLLDLGVAGYVLKRSAT
CEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHCCHHHHHHHHHHH
EELIRGIHAVGSGGIYLDPAIAGRAIGRTTPHLHNGDEHNAVSELSTREIEVLRLAAIGH
HHHHHHHHHCCCCCEEECHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECC
SNKTIAAKLQIGAKSVETYKARGMAKLGFHNRVEVVRFALSMGWLSDP
CCCEEEEEEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKATAMDQQSPSRLRVFIADDHPVVLSGMKALVAGDPGLEVVGEASDGPNALRRATELKP
CCCCCCCCCCCCEEEEEEECCCCEEHHCCHHEECCCCCCEEEECCCCCHHHHHHHHHCCC
DVAVLDLSMPGLNGIEVARKFLAACPDCRVLVLTVHEDGAYLRQLLDLGVAGYVLKRSAT
CEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHCCHHHHHHHHHHH
EELIRGIHAVGSGGIYLDPAIAGRAIGRTTPHLHNGDEHNAVSELSTREIEVLRLAAIGH
HHHHHHHHHCCCCCEEECHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECC
SNKTIAAKLQIGAKSVETYKARGMAKLGFHNRVEVVRFALSMGWLSDP
CCCEEEEEEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]