| Definition | Rhodopseudomonas palustris TIE-1 chromosome, complete genome. |
|---|---|
| Accession | NC_011004 |
| Length | 5,744,041 |
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The map label for this gene is xecD [H]
Identifier: 192289896
GI number: 192289896
Start: 1571029
End: 1571880
Strand: Reverse
Name: xecD [H]
Synonym: Rpal_1488
Alternate gene names: 192289896
Gene position: 1571880-1571029 (Counterclockwise)
Preceding gene: 192289897
Following gene: 192289894
Centisome position: 27.37
GC content: 68.66
Gene sequence:
>852_bases ATGCCGCATCCCGCCATTGCCAAGGATCAGGTCGCCGTGGTCACCGGCGGCGCATCGGGGATCGGCTTTGCGGCCGCCAA GCGGTTTCTGCAGGCCGGCATGAAGGTGGCGATCGCGGATCTGAACGCCGATCATCTCGCCCGCGCCGCGGAGCTGCTGG CGCATGTCGCCAGCAGCGGAGCCGACGACGTGCTGGCGAAGGAAACTGACGTCGCCAAACCCGACCAGCTCGAGGCGCTG CGCGCCGCCGTCACCGCGCGGTTCGGCGACGTCGACGTGGTGATGAACAATGCCGGCATCGAGCCGCCGAGCACCGCGCT CGGCCCGCGCGAGGCCTATGAGCGCATCCTCAGCGTCAATCTGTGGGGGGTGATCCACGGCTCGCAGATCTTCGCGCCGG ACATGATCGCGCGCGGCCGGCCGGGGCTGATCATCAACACCGGCTCCAAGCAGGGCATTACCACGCCGCCGGGCAATCCG GCCTACAATGTCTCCAAGGCCGGTGTGAAAGCCTATACCGAAGCGTTGGCGCATGAGCTGCGCACCACCGAGGGCTGCGC GGTGACGGCGCATCTGCTCATCCCCGGCTTCGTCTTCACCGCGCTGACCGCGCGCGGGCGCAGCGAGAAGCCGGCCGGCG CCTGGACCGCCGAGCAGACCGTGGACTTCATGCTGGCGCGGCTTGAGGACAGCGACTTCTACATCCTGTGCCCGGACAAT GACGTGCCCCGAAGCCTCGACGAACGCCGCATCGCCTGGGCCGCCGGCGACATCATCGACAACCGCCCCGCGCTGTCGCG CTGGCACCCGGCCTGGGTCGACCGCTTCAGGGCGTTCGTCGAAGGGAAGTAA
Upstream 100 bases:
>100_bases CGCTCGCAATGACGATCAAAGTCCGCACGTCCCCTCGGCTTGCGTCCTCCGCCGCTGCGCTTATCTCCCGGGCATCGCCA TCCGCCTCGAGGAGACCGCC
Downstream 100 bases:
>100_bases CAAGCCACGGCGCCAGCGTCTTCGTGAGAGCCTGACCGGAAATGCGGGCAGCTAATTGAAAGGCTTTGATAAGCCGTTCA ATTGACGATTAGTTTCGTCA
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: R-HPCDH; Aliphatic epoxide carboxylation component III [H]
Number of amino acids: Translated: 283; Mature: 282
Protein sequence:
>283_residues MPHPAIAKDQVAVVTGGASGIGFAAAKRFLQAGMKVAIADLNADHLARAAELLAHVASSGADDVLAKETDVAKPDQLEAL RAAVTARFGDVDVVMNNAGIEPPSTALGPREAYERILSVNLWGVIHGSQIFAPDMIARGRPGLIINTGSKQGITTPPGNP AYNVSKAGVKAYTEALAHELRTTEGCAVTAHLLIPGFVFTALTARGRSEKPAGAWTAEQTVDFMLARLEDSDFYILCPDN DVPRSLDERRIAWAAGDIIDNRPALSRWHPAWVDRFRAFVEGK
Sequences:
>Translated_283_residues MPHPAIAKDQVAVVTGGASGIGFAAAKRFLQAGMKVAIADLNADHLARAAELLAHVASSGADDVLAKETDVAKPDQLEAL RAAVTARFGDVDVVMNNAGIEPPSTALGPREAYERILSVNLWGVIHGSQIFAPDMIARGRPGLIINTGSKQGITTPPGNP AYNVSKAGVKAYTEALAHELRTTEGCAVTAHLLIPGFVFTALTARGRSEKPAGAWTAEQTVDFMLARLEDSDFYILCPDN DVPRSLDERRIAWAAGDIIDNRPALSRWHPAWVDRFRAFVEGK >Mature_282_residues PHPAIAKDQVAVVTGGASGIGFAAAKRFLQAGMKVAIADLNADHLARAAELLAHVASSGADDVLAKETDVAKPDQLEALR AAVTARFGDVDVVMNNAGIEPPSTALGPREAYERILSVNLWGVIHGSQIFAPDMIARGRPGLIINTGSKQGITTPPGNPA YNVSKAGVKAYTEALAHELRTTEGCAVTAHLLIPGFVFTALTARGRSEKPAGAWTAEQTVDFMLARLEDSDFYILCPDND VPRSLDERRIAWAAGDIIDNRPALSRWHPAWVDRFRAFVEGK
Specific function: Catalyzes the oxidation of 2-(R)-hydroxyalkyl thioesters of CoM to 2-oxoalkyl thioesters of CoM. The enzyme highly specific for the R enantiomers [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI31542939, Length=218, Percent_Identity=32.5688073394495, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI20149619, Length=205, Percent_Identity=29.2682926829268, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI7706318, Length=189, Percent_Identity=26.984126984127, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI83715985, Length=186, Percent_Identity=31.7204301075269, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI4758504, Length=186, Percent_Identity=31.7204301075269, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI224922801, Length=177, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI109715829, Length=235, Percent_Identity=28.0851063829787, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI25282469, Length=223, Percent_Identity=26.457399103139, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI40254992, Length=202, Percent_Identity=28.7128712871287, Blast_Score=66, Evalue=5e-11, Organism=Homo sapiens, GI32483357, Length=197, Percent_Identity=27.4111675126904, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1789208, Length=217, Percent_Identity=29.4930875576037, Blast_Score=74, Evalue=8e-15, Organism=Escherichia coli, GI1787335, Length=195, Percent_Identity=29.7435897435897, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787820, Length=192, Percent_Identity=28.6458333333333, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI1787905, Length=130, Percent_Identity=29.2307692307692, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1789057, Length=192, Percent_Identity=30.2083333333333, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1790717, Length=210, Percent_Identity=26.6666666666667, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI87082160, Length=203, Percent_Identity=28.5714285714286, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI17555706, Length=197, Percent_Identity=31.9796954314721, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI25147288, Length=201, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI71994600, Length=219, Percent_Identity=26.9406392694064, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71994604, Length=226, Percent_Identity=29.2035398230088, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17538486, Length=223, Percent_Identity=29.1479820627803, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17567345, Length=230, Percent_Identity=28.2608695652174, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17559104, Length=216, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17560332, Length=215, Percent_Identity=29.3023255813954, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17561402, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17562910, Length=184, Percent_Identity=26.0869565217391, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17562908, Length=229, Percent_Identity=30.1310043668122, Blast_Score=67, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17564282, Length=213, Percent_Identity=24.4131455399061, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17562906, Length=179, Percent_Identity=31.8435754189944, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI193204405, Length=203, Percent_Identity=32.0197044334975, Blast_Score=64, Evalue=1e-10, Organism=Saccharomyces cerevisiae, GI6323882, Length=215, Percent_Identity=26.9767441860465, Blast_Score=67, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6322067, Length=176, Percent_Identity=28.9772727272727, Blast_Score=66, Evalue=6e-12, Organism=Saccharomyces cerevisiae, GI6320089, Length=202, Percent_Identity=25.7425742574257, Blast_Score=65, Evalue=9e-12, Organism=Drosophila melanogaster, GI24644339, Length=198, Percent_Identity=32.3232323232323, Blast_Score=97, Evalue=9e-21, Organism=Drosophila melanogaster, GI21357041, Length=206, Percent_Identity=32.0388349514563, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI21355631, Length=176, Percent_Identity=31.8181818181818, Blast_Score=91, Evalue=6e-19, Organism=Drosophila melanogaster, GI28571526, Length=200, Percent_Identity=32, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI221331218, Length=171, Percent_Identity=36.2573099415205, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24665243, Length=171, Percent_Identity=36.2573099415205, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI221331216, Length=172, Percent_Identity=36.6279069767442, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24665247, Length=172, Percent_Identity=36.6279069767442, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24665264, Length=195, Percent_Identity=31.7948717948718, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=26.7676767676768, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI23397609, Length=193, Percent_Identity=31.6062176165803, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24649181, Length=192, Percent_Identity=26.5625, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI17737361, Length=209, Percent_Identity=28.7081339712919, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI24584752, Length=208, Percent_Identity=29.8076923076923, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI116007232, Length=181, Percent_Identity=31.4917127071823, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI116007234, Length=181, Percent_Identity=31.4917127071823, Blast_Score=65, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.268 [H]
Molecular weight: Translated: 30183; Mature: 30051
Theoretical pI: Translated: 6.40; Mature: 6.40
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPHPAIAKDQVAVVTGGASGIGFAAAKRFLQAGMKVAIADLNADHLARAAELLAHVASSG CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCC ADDVLAKETDVAKPDQLEALRAAVTARFGDVDVVMNNAGIEPPSTALGPREAYERILSVN CCHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHH LWGVIHGSQIFAPDMIARGRPGLIINTGSKQGITTPPGNPAYNVSKAGVKAYTEALAHEL EEEEEECCEECCCHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH RTTEGCAVTAHLLIPGFVFTALTARGRSEKPAGAWTAEQTVDFMLARLEDSDFYILCPDN HCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCC DVPRSLDERRIAWAAGDIIDNRPALSRWHPAWVDRFRAFVEGK CCCCCHHHHHHHHHHCCHHCCCCCHHHCCHHHHHHHHHHHCCC >Mature Secondary Structure PHPAIAKDQVAVVTGGASGIGFAAAKRFLQAGMKVAIADLNADHLARAAELLAHVASSG CCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCC ADDVLAKETDVAKPDQLEALRAAVTARFGDVDVVMNNAGIEPPSTALGPREAYERILSVN CCHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHH LWGVIHGSQIFAPDMIARGRPGLIINTGSKQGITTPPGNPAYNVSKAGVKAYTEALAHEL EEEEEECCEECCCHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH RTTEGCAVTAHLLIPGFVFTALTARGRSEKPAGAWTAEQTVDFMLARLEDSDFYILCPDN HCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCC DVPRSLDERRIAWAAGDIIDNRPALSRWHPAWVDRFRAFVEGK CCCCCHHHHHHHHHHCCHHCCCCCHHHCCHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7704278; 9405410; 12524213 [H]