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The map label for this gene is fabH [H]

Identifier: 192289897

GI number: 192289897

Start: 1572069

End: 1573184

Strand: Reverse

Name: fabH [H]

Synonym: Rpal_1489

Alternate gene names: 192289897

Gene position: 1573184-1572069 (Counterclockwise)

Preceding gene: 192289900

Following gene: 192289896

Centisome position: 27.39

GC content: 65.05

Gene sequence:

>1116_bases
GTGCGCCCTGCCGTCATTGCCGCGACCGGCCTCTACACCCCGCCCGACAGCGTTTCCAATGCCGAGCTGGTGGAGGCGTT
CAACACCTATGTGGCGAACTTCAACGCGGCGAACAAAGCGCGGATCGAAGCTGGCGAGATCGAGCCGCTGCAGCCGTCGT
CCTCCGAATTCATCGAGAAGGCCTCGGGCATCAAGTCGCGCTACGTCGTGGCCAAGCCGGGCATCGTCGATCCGGAGATC
ATGCGCCCGATCATTCCGGAGCGCTCCAACGACGAATTGTCGATCCTCGCCGAGATGGCGGTGACCGCGGCCGAACAGGC
GATCGAACGCTGGGGCAAGCCGCGCGAGCGGATCGGCGCGGTGCTGTGCGCCTGCTCCAACATGCAGCGCGCCTATCCGG
CGATGGCGATCGAGGTGCAGAACGCGCTGGGGCTCGGCGGCTTCGCGTTCGACATGAACGTCGCCTGCTCGTCGGCGACC
TTCGGGCTGAAGACCGCGGCGGATTTCGTCGGCGGCGGCTCGGTCGATGCGGTGCTGATGGTCAATCCGGAGATCTGCTC
CGGCCATCTCAACTTCCGCGACCGCGACAGTCACTTCATCTTCGGCGACGTCGCCACCGCGGCGATCGTCGAGCGCGCCG
ACGATGCGCAGGGCGGCTGGTCGATCCTCGGCACCAAGCTGAAGACGCAGTTCTCCAACAACATCCGCAACAACGCCGGC
TTCCTCAACCGCGCGTGGCCGGAAGGCCGCGACAACGCCGACAAGCTGTTCGTGCAGCAGGGTCGCAAGGTGTTCAAGGA
AGTGGTGCCGCTGGTGTCGGAGATGATCATCGAGCACGCCCGCGAGATCGGCATCGATCCGCACGGCCTGAAGCGGATGT
GGCTGCACCAGGCCAACATCAACATGAACGAGATCATCGGCCGCAAAGTGCTGGGCCGCGATCCGACGCGGGACGAAAAC
GTCATCATCCTCGACGACTACGCCAACACCTCGTCGGCGGGCTCGATCATCGCCTTCCACAAGCACCAGGATGACATGGC
GTCCGGCGACCTCGGCCTGATCTGCTCGTTCGGCGCCGGCTACTCGGCCGGCACGGTGTTCGTGCAGAAGCGGTAA

Upstream 100 bases:

>100_bases
TCAAAGCAGACGCAGGTGAAACGGCGTCGGATACCGGCAGGGCGCGGCGGATCGCTTGGCCGGCGGTCCTCTCACTCAGC
CACTGAGCCTGGAGCTTTCC

Downstream 100 bases:

>100_bases
CAGTCTCACATCGCGCTGTCCCCGGCATTGCGAGGCGCGAAGCGACGAAGCGATCAGAAGCCAGGTACACGGCGTCGCTG
AATTGCTTCGCTCGCAATGA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MRPAVIAATGLYTPPDSVSNAELVEAFNTYVANFNAANKARIEAGEIEPLQPSSSEFIEKASGIKSRYVVAKPGIVDPEI
MRPIIPERSNDELSILAEMAVTAAEQAIERWGKPRERIGAVLCACSNMQRAYPAMAIEVQNALGLGGFAFDMNVACSSAT
FGLKTAADFVGGGSVDAVLMVNPEICSGHLNFRDRDSHFIFGDVATAAIVERADDAQGGWSILGTKLKTQFSNNIRNNAG
FLNRAWPEGRDNADKLFVQQGRKVFKEVVPLVSEMIIEHAREIGIDPHGLKRMWLHQANINMNEIIGRKVLGRDPTRDEN
VIILDDYANTSSAGSIIAFHKHQDDMASGDLGLICSFGAGYSAGTVFVQKR

Sequences:

>Translated_371_residues
MRPAVIAATGLYTPPDSVSNAELVEAFNTYVANFNAANKARIEAGEIEPLQPSSSEFIEKASGIKSRYVVAKPGIVDPEI
MRPIIPERSNDELSILAEMAVTAAEQAIERWGKPRERIGAVLCACSNMQRAYPAMAIEVQNALGLGGFAFDMNVACSSAT
FGLKTAADFVGGGSVDAVLMVNPEICSGHLNFRDRDSHFIFGDVATAAIVERADDAQGGWSILGTKLKTQFSNNIRNNAG
FLNRAWPEGRDNADKLFVQQGRKVFKEVVPLVSEMIIEHAREIGIDPHGLKRMWLHQANINMNEIIGRKVLGRDPTRDEN
VIILDDYANTSSAGSIIAFHKHQDDMASGDLGLICSFGAGYSAGTVFVQKR
>Mature_371_residues
MRPAVIAATGLYTPPDSVSNAELVEAFNTYVANFNAANKARIEAGEIEPLQPSSSEFIEKASGIKSRYVVAKPGIVDPEI
MRPIIPERSNDELSILAEMAVTAAEQAIERWGKPRERIGAVLCACSNMQRAYPAMAIEVQNALGLGGFAFDMNVACSSAT
FGLKTAADFVGGGSVDAVLMVNPEICSGHLNFRDRDSHFIFGDVATAAIVERADDAQGGWSILGTKLKTQFSNNIRNNAG
FLNRAWPEGRDNADKLFVQQGRKVFKEVVPLVSEMIIEHAREIGIDPHGLKRMWLHQANINMNEIIGRKVLGRDPTRDEN
VIILDDYANTSSAGSIIAFHKHQDDMASGDLGLICSFGAGYSAGTVFVQKR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=331, Percent_Identity=27.7945619335347, Blast_Score=106, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 40243; Mature: 40243

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAVIAATGLYTPPDSVSNAELVEAFNTYVANFNAANKARIEAGEIEPLQPSSSEFIEK
CCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHH
ASGIKSRYVVAKPGIVDPEIMRPIIPERSNDELSILAEMAVTAAEQAIERWGKPRERIGA
HCCCCCEEEEECCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VLCACSNMQRAYPAMAIEVQNALGLGGFAFDMNVACSSATFGLKTAADFVGGGSVDAVLM
HHHHHHCHHHHCCEEEEEEHHHCCCCEEEEECCEEECCCCCCHHHHHHHCCCCCCCEEEE
VNPEICSGHLNFRDRDSHFIFGDVATAAIVERADDAQGGWSILGTKLKTQFSNNIRNNAG
ECCHHHCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCC
FLNRAWPEGRDNADKLFVQQGRKVFKEVVPLVSEMIIEHAREIGIDPHGLKRMWLHQANI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
NMNEIIGRKVLGRDPTRDENVIILDDYANTSSAGSIIAFHKHQDDMASGDLGLICSFGAG
CHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCC
YSAGTVFVQKR
CCCCEEEEEEC
>Mature Secondary Structure
MRPAVIAATGLYTPPDSVSNAELVEAFNTYVANFNAANKARIEAGEIEPLQPSSSEFIEK
CCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHH
ASGIKSRYVVAKPGIVDPEIMRPIIPERSNDELSILAEMAVTAAEQAIERWGKPRERIGA
HCCCCCEEEEECCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VLCACSNMQRAYPAMAIEVQNALGLGGFAFDMNVACSSATFGLKTAADFVGGGSVDAVLM
HHHHHHCHHHHCCEEEEEEHHHCCCCEEEEECCEEECCCCCCHHHHHHHCCCCCCCEEEE
VNPEICSGHLNFRDRDSHFIFGDVATAAIVERADDAQGGWSILGTKLKTQFSNNIRNNAG
ECCHHHCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCC
FLNRAWPEGRDNADKLFVQQGRKVFKEVVPLVSEMIIEHAREIGIDPHGLKRMWLHQANI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
NMNEIIGRKVLGRDPTRDENVIILDDYANTSSAGSIIAFHKHQDDMASGDLGLICSFGAG
CHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCC
YSAGTVFVQKR
CCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA