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The map label for this gene is mmgC [H]

Identifier: 192289839

GI number: 192289839

Start: 1509534

End: 1510730

Strand: Reverse

Name: mmgC [H]

Synonym: Rpal_1429

Alternate gene names: 192289839

Gene position: 1510730-1509534 (Counterclockwise)

Preceding gene: 192289840

Following gene: 192289826

Centisome position: 26.3

GC content: 66.42

Gene sequence:

>1197_bases
ATGGACATGACCTTCGGCGACGCCGAGCTCGCCTTCCAGCAAGAGGTCCGCGATTTCATCGCGGCGAATCTGACGCCCGA
CATGAAGCGGGCCGAGTCGCTCAACGCCTCGGTGTTCTCCGAGCCGGAGACCGGCGTGCCGTGGCAGCGCGCCCTCAACG
CCAAGGGCTGGGGCGCGCCGGGCTGGCCGGTCGAATATGGCGGCACCGGCTGGACGCCGGCACAGCGCTGGATTTTCGAA
ACCGAATGCGCCCATGCGGGCGTGCCCTCCCCGACGCCGATGGGCGTCAAGATGGTCGGCCCCGTGATCATCGGCTTCGG
CTCGCCCGAGCAGAAGAACTACTTCCTGCCGCGGATTCTGTCCTGCGAGGATTATTGGTGCCAGGGCTATTCGGAGCCGG
GCTCGGGCTCGGACCTGTCGTCGCTGAAGACCCGCGCGGTCCGCGACGGCGATGAGTACGTCATCAACGGTACCAAGATC
TGGACCACCCACGCGCACAACGCCAACATGATGTTCGCGCTGGTGCGCACCAGCGACGAGCCGCGGCAGCAGGATGGCAT
CAGCTTCGTGCTGATCGACATGAAGAGCCCCGGCATCACCATCCGCCCGATTCTCACGATCGGCGGCGACCACGAGGTCA
ATCAGGTGTTCTTCGACGACGTCCGGATTCCGGCGTCGAACCTGGTCGGCCAGGAAGGCAAGGGCTGGACCTACGGCAAG
TATCTGCTGGAATTCGAGCGCGGCTCCGGCATCGCCTCGGCCAAGCTCCGCAAGGCACTGCACCGGACGGCGGCGCTCGC
GGAGTCGGAGGCGACCGGCCGGGCGATCGAGGATCCGGAGATCGCGATCCGGATGTCGGAGGCCGAGGTCGATATCGACG
CGCTGGAAATGACCGAGCTGCGGGTGCTATCGGCGCTGCAGAATGGCCAGAACCCAGGCGCGGTGTCGTCGATCCTCAAA
CTGCGCACCAGCGAGATCTACCAGGCGGTGAGCCGGCTCGGCGTCGACGTCATCGGCACCGACGGCCTCTATGTCGAACC
GACCCGCCCGCTGCACCGGCTCAACGCGCCGCCGGCGATTCCGGAGGACGAACTCGCCGTGATGCCGACGCACCTCAACG
GCCGCGCCTACACCATCTTCGGCGGCACCTCCGAGATCCAGCGCGACATCATCAGCAAGCTGGTGCTGGGGTTGTAG

Upstream 100 bases:

>100_bases
CCTGCTGGCGTTCGAGACGCTGTTCGGCGGCAGCACCCATCATTATCGCCGCCACGCCGCGCTCAGCGGCCGGCCTGTTT
AAGCAAAGCGAGGCATCGAC

Downstream 100 bases:

>100_bases
GGAACCAGCACCGTCGTCATTGCGAGCGAAGCGAAGCGATCACGAAGCGCAGTGCGCGACGCTGGATTGCTTCGTAGCTT
CGCTCCTCGCAATGAGAAAT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MDMTFGDAELAFQQEVRDFIAANLTPDMKRAESLNASVFSEPETGVPWQRALNAKGWGAPGWPVEYGGTGWTPAQRWIFE
TECAHAGVPSPTPMGVKMVGPVIIGFGSPEQKNYFLPRILSCEDYWCQGYSEPGSGSDLSSLKTRAVRDGDEYVINGTKI
WTTHAHNANMMFALVRTSDEPRQQDGISFVLIDMKSPGITIRPILTIGGDHEVNQVFFDDVRIPASNLVGQEGKGWTYGK
YLLEFERGSGIASAKLRKALHRTAALAESEATGRAIEDPEIAIRMSEAEVDIDALEMTELRVLSALQNGQNPGAVSSILK
LRTSEIYQAVSRLGVDVIGTDGLYVEPTRPLHRLNAPPAIPEDELAVMPTHLNGRAYTIFGGTSEIQRDIISKLVLGL

Sequences:

>Translated_398_residues
MDMTFGDAELAFQQEVRDFIAANLTPDMKRAESLNASVFSEPETGVPWQRALNAKGWGAPGWPVEYGGTGWTPAQRWIFE
TECAHAGVPSPTPMGVKMVGPVIIGFGSPEQKNYFLPRILSCEDYWCQGYSEPGSGSDLSSLKTRAVRDGDEYVINGTKI
WTTHAHNANMMFALVRTSDEPRQQDGISFVLIDMKSPGITIRPILTIGGDHEVNQVFFDDVRIPASNLVGQEGKGWTYGK
YLLEFERGSGIASAKLRKALHRTAALAESEATGRAIEDPEIAIRMSEAEVDIDALEMTELRVLSALQNGQNPGAVSSILK
LRTSEIYQAVSRLGVDVIGTDGLYVEPTRPLHRLNAPPAIPEDELAVMPTHLNGRAYTIFGGTSEIQRDIISKLVLGL
>Mature_398_residues
MDMTFGDAELAFQQEVRDFIAANLTPDMKRAESLNASVFSEPETGVPWQRALNAKGWGAPGWPVEYGGTGWTPAQRWIFE
TECAHAGVPSPTPMGVKMVGPVIIGFGSPEQKNYFLPRILSCEDYWCQGYSEPGSGSDLSSLKTRAVRDGDEYVINGTKI
WTTHAHNANMMFALVRTSDEPRQQDGISFVLIDMKSPGITIRPILTIGGDHEVNQVFFDDVRIPASNLVGQEGKGWTYGK
YLLEFERGSGIASAKLRKALHRTAALAESEATGRAIEDPEIAIRMSEAEVDIDALEMTELRVLSALQNGQNPGAVSSILK
LRTSEIYQAVSRLGVDVIGTDGLYVEPTRPLHRLNAPPAIPEDELAVMPTHLNGRAYTIFGGTSEIQRDIISKLVLGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=397, Percent_Identity=28.7153652392947, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4557231, Length=404, Percent_Identity=25.4950495049505, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI187960098, Length=404, Percent_Identity=25.4950495049505, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI4501857, Length=407, Percent_Identity=24.0786240786241, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI4501859, Length=242, Percent_Identity=29.7520661157025, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI226958412, Length=395, Percent_Identity=24.0506329113924, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=25, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI7656849, Length=405, Percent_Identity=23.7037037037037, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI21361497, Length=241, Percent_Identity=28.2157676348548, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI4557235, Length=180, Percent_Identity=31.6666666666667, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI76496475, Length=180, Percent_Identity=31.6666666666667, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI38505218, Length=256, Percent_Identity=26.5625, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87081958, Length=355, Percent_Identity=23.943661971831, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786223, Length=251, Percent_Identity=25.8964143426295, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=414, Percent_Identity=24.8792270531401, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17569725, Length=416, Percent_Identity=26.4423076923077, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17538396, Length=252, Percent_Identity=30.5555555555556, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=343, Percent_Identity=28.2798833819242, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17534899, Length=301, Percent_Identity=28.2392026578073, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17551932, Length=351, Percent_Identity=26.7806267806268, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17506239, Length=349, Percent_Identity=28.9398280802292, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32563615, Length=185, Percent_Identity=36.7567567567568, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17505929, Length=295, Percent_Identity=26.4406779661017, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=192, Percent_Identity=32.2916666666667, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI71982178, Length=249, Percent_Identity=24.8995983935743, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71985184, Length=149, Percent_Identity=30.8724832214765, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=145, Percent_Identity=31.0344827586207, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17534353, Length=409, Percent_Identity=23.2273838630807, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24660351, Length=311, Percent_Identity=29.2604501607717, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281363737, Length=199, Percent_Identity=32.1608040201005, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355753, Length=245, Percent_Identity=30.2040816326531, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21356377, Length=404, Percent_Identity=26.4851485148515, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24666513, Length=160, Percent_Identity=36.875, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646207, Length=401, Percent_Identity=25.1870324189526, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43521; Mature: 43521

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMTFGDAELAFQQEVRDFIAANLTPDMKRAESLNASVFSEPETGVPWQRALNAKGWGAP
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCCCCHHHHCCCCCCCCC
GWPVEYGGTGWTPAQRWIFETECAHAGVPSPTPMGVKMVGPVIIGFGSPEQKNYFLPRIL
CCCEECCCCCCCHHHHEEEEECHHHCCCCCCCCCCEEEECEEEEECCCCCCCCCCCCEEE
SCEDYWCQGYSEPGSGSDLSSLKTRAVRDGDEYVINGTKIWTTHAHNANMMFALVRTSDE
CCCHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECEEEEEEECCCCCEEEEEEECCCC
PRQQDGISFVLIDMKSPGITIRPILTIGGDHEVNQVFFDDVRIPASNLVGQEGKGWTYGK
CHHHCCCEEEEEEECCCCEEEEEEEEECCCCCCCCEEECCCCCCHHHHCCCCCCCCEEEE
YLLEFERGSGIASAKLRKALHRTAALAESEATGRAIEDPEIAIRMSEAEVDIDALEMTEL
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHH
RVLSALQNGQNPGAVSSILKLRTSEIYQAVSRLGVDVIGTDGLYVEPTRPLHRLNAPPAI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCCCHHHHCCCCCCC
PEDELAVMPTHLNGRAYTIFGGTSEIQRDIISKLVLGL
CCCCEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDMTFGDAELAFQQEVRDFIAANLTPDMKRAESLNASVFSEPETGVPWQRALNAKGWGAP
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCCCCHHHHCCCCCCCCC
GWPVEYGGTGWTPAQRWIFETECAHAGVPSPTPMGVKMVGPVIIGFGSPEQKNYFLPRIL
CCCEECCCCCCCHHHHEEEEECHHHCCCCCCCCCCEEEECEEEEECCCCCCCCCCCCEEE
SCEDYWCQGYSEPGSGSDLSSLKTRAVRDGDEYVINGTKIWTTHAHNANMMFALVRTSDE
CCCHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECEEEEEEECCCCCEEEEEEECCCC
PRQQDGISFVLIDMKSPGITIRPILTIGGDHEVNQVFFDDVRIPASNLVGQEGKGWTYGK
CHHHCCCEEEEEEECCCCEEEEEEEEECCCCCCCCEEECCCCCCHHHHCCCCCCCCEEEE
YLLEFERGSGIASAKLRKALHRTAALAESEATGRAIEDPEIAIRMSEAEVDIDALEMTEL
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHH
RVLSALQNGQNPGAVSSILKLRTSEIYQAVSRLGVDVIGTDGLYVEPTRPLHRLNAPPAI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCCCHHHHCCCCCCC
PEDELAVMPTHLNGRAYTIFGGTSEIQRDIISKLVLGL
CCCCEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]