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The map label for this gene is crt [H]

Identifier: 192289454

GI number: 192289454

Start: 1091065

End: 1091859

Strand: Reverse

Name: crt [H]

Synonym: Rpal_1027

Alternate gene names: 192289454

Gene position: 1091859-1091065 (Counterclockwise)

Preceding gene: 192289455

Following gene: 192289452

Centisome position: 19.01

GC content: 63.02

Gene sequence:

>795_bases
ATGCGGGGACGCCTGGTCTTAGGGGGAAATGCCATGACGGAGCATCTGATCGTCACGGATGAAGACGGCACGCGGGTGAT
CACCATGCGCCGGCCGGAAAAGAAGAACGCGCTGACGCAGGACATGTATCGCGAGATGAGCCACGCGATCGACACCGCGC
AGAACAATCCCGACATCCGCTGCCTGATCATCACCGGCGGTTCCGGCGTGTTCACCGCCGGCAACGATCTCGACGATTTC
CTCAAAGCCGGCACCGATACCAGCGGCGCGGCGCGCGTCACCAACGCCACCAAATTTCTGTATTCGCTGGCTCATAATGT
GAAGCCGATCATTGCGGCCGTCGACGGCATCGCGATCGGCATCGGCACCACGATGCTGTTTCACTGCGACTACGTGCTGG
CCTCGACCACGGCGACGTTCTCGACGCCATTCATCCAGCTCGGACTGGTGCCGGAGGGTGCATCCAGCCTGCTGATGCCG
CGCACCATGGGCTATCAGCGCGCGTTCGCCACGCTGGTGATGGGCCACACCATGACGGCCGAGAACGCGCGCGTCGCCGG
TTTCGTCAACGTCGTCGTGGCGCCCGGCCAGACCGAAATGGAAGCCAAGAAAGCCGCGCGGGAAATCTGCGCGCTGCCGG
CCGAAGCGGTGGCGATCTCACGTAAGCTGCTGCGGCTGGCGCCCGACGAGATCACCCGCCGGATCGATCAGGAAACGCAT
CTGTTCGGCGAGCGAATGAAATCGCCCGAAGCCGTCAACGCCTTCATGCGGTTCTTCCAGCGGAAGAAGGCATGA

Upstream 100 bases:

>100_bases
AAGGCCTGCGCTTCGACAGAAATTCGTCGCGGGCGGCGGGGGCGTCAGCTGACGTCACGGACGAACGTGATACGGTGCGT
ACCGAGGAGCGCTCCGCTCG

Downstream 100 bases:

>100_bases
GCCTGTGCGGCACCCGCCGGGTGCCGCAGCCGAGCTGATTACTTTTTCCCCGGTGCGAAATCCTGATCGCTGAACGGGTT
CGACGATGGCGTCCGCAAAT

Product: Enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MRGRLVLGGNAMTEHLIVTDEDGTRVITMRRPEKKNALTQDMYREMSHAIDTAQNNPDIRCLIITGGSGVFTAGNDLDDF
LKAGTDTSGAARVTNATKFLYSLAHNVKPIIAAVDGIAIGIGTTMLFHCDYVLASTTATFSTPFIQLGLVPEGASSLLMP
RTMGYQRAFATLVMGHTMTAENARVAGFVNVVVAPGQTEMEAKKAAREICALPAEAVAISRKLLRLAPDEITRRIDQETH
LFGERMKSPEAVNAFMRFFQRKKA

Sequences:

>Translated_264_residues
MRGRLVLGGNAMTEHLIVTDEDGTRVITMRRPEKKNALTQDMYREMSHAIDTAQNNPDIRCLIITGGSGVFTAGNDLDDF
LKAGTDTSGAARVTNATKFLYSLAHNVKPIIAAVDGIAIGIGTTMLFHCDYVLASTTATFSTPFIQLGLVPEGASSLLMP
RTMGYQRAFATLVMGHTMTAENARVAGFVNVVVAPGQTEMEAKKAAREICALPAEAVAISRKLLRLAPDEITRRIDQETH
LFGERMKSPEAVNAFMRFFQRKKA
>Mature_264_residues
MRGRLVLGGNAMTEHLIVTDEDGTRVITMRRPEKKNALTQDMYREMSHAIDTAQNNPDIRCLIITGGSGVFTAGNDLDDF
LKAGTDTSGAARVTNATKFLYSLAHNVKPIIAAVDGIAIGIGTTMLFHCDYVLASTTATFSTPFIQLGLVPEGASSLLMP
RTMGYQRAFATLVMGHTMTAENARVAGFVNVVVAPGQTEMEAKKAAREICALPAEAVAISRKLLRLAPDEITRRIDQETH
LFGERMKSPEAVNAFMRFFQRKKA

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI45643119, Length=253, Percent_Identity=33.596837944664, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI260275230, Length=253, Percent_Identity=33.596837944664, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI260274832, Length=253, Percent_Identity=33.596837944664, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI4757968, Length=252, Percent_Identity=27.3809523809524, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI49355787, Length=252, Percent_Identity=27.3809523809524, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI221136756, Length=252, Percent_Identity=27.7777777777778, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI221136753, Length=252, Percent_Identity=27.7777777777778, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI221307494, Length=255, Percent_Identity=28.2352941176471, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI25453481, Length=255, Percent_Identity=27.0588235294118, Blast_Score=104, Evalue=6e-23,
Organism=Homo sapiens, GI51538573, Length=255, Percent_Identity=27.0588235294118, Blast_Score=104, Evalue=6e-23,
Organism=Homo sapiens, GI4757966, Length=214, Percent_Identity=29.4392523364486, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI51538581, Length=214, Percent_Identity=29.4392523364486, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI116235487, Length=258, Percent_Identity=25.968992248062, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI194097323, Length=243, Percent_Identity=25.9259259259259, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI31542718, Length=203, Percent_Identity=26.6009852216749, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI68989263, Length=204, Percent_Identity=26.9607843137255, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI20127408, Length=174, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI70995211, Length=179, Percent_Identity=29.0502793296089, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4502327, Length=176, Percent_Identity=26.1363636363636, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787660, Length=257, Percent_Identity=29.1828793774319, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787659, Length=229, Percent_Identity=28.82096069869, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI221142681, Length=217, Percent_Identity=29.4930875576037, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788597, Length=191, Percent_Identity=29.3193717277487, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082183, Length=241, Percent_Identity=26.5560165975104, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790281, Length=177, Percent_Identity=26.5536723163842, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17535521, Length=251, Percent_Identity=35.0597609561753, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17549921, Length=243, Percent_Identity=32.9218106995885, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI25145438, Length=219, Percent_Identity=28.310502283105, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17554946, Length=195, Percent_Identity=27.6923076923077, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17540714, Length=216, Percent_Identity=27.7777777777778, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536985, Length=139, Percent_Identity=30.2158273381295, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=252, Percent_Identity=22.2222222222222, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=165, Percent_Identity=24.8484848484848, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=190, Percent_Identity=25.2631578947368, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24654903, Length=253, Percent_Identity=28.4584980237154, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI20129971, Length=184, Percent_Identity=30.4347826086957, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653477, Length=184, Percent_Identity=30.4347826086957, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19922422, Length=214, Percent_Identity=22.4299065420561, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19920382, Length=176, Percent_Identity=26.7045454545455, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24653139, Length=225, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 28723; Mature: 28723

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGRLVLGGNAMTEHLIVTDEDGTRVITMRRPEKKNALTQDMYREMSHAIDTAQNNPDIR
CCCCEEECCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
CLIITGGSGVFTAGNDLDDFLKAGTDTSGAARVTNATKFLYSLAHNVKPIIAAVDGIAIG
EEEEECCCEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCHHH
IGTTMLFHCDYVLASTTATFSTPFIQLGLVPEGASSLLMPRTMGYQRAFATLVMGHTMTA
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCC
ENARVAGFVNVVVAPGQTEMEAKKAAREICALPAEAVAISRKLLRLAPDEITRRIDQETH
CCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
LFGERMKSPEAVNAFMRFFQRKKA
HHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRGRLVLGGNAMTEHLIVTDEDGTRVITMRRPEKKNALTQDMYREMSHAIDTAQNNPDIR
CCCCEEECCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
CLIITGGSGVFTAGNDLDDFLKAGTDTSGAARVTNATKFLYSLAHNVKPIIAAVDGIAIG
EEEEECCCEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCHHH
IGTTMLFHCDYVLASTTATFSTPFIQLGLVPEGASSLLMPRTMGYQRAFATLVMGHTMTA
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCC
ENARVAGFVNVVVAPGQTEMEAKKAAREICALPAEAVAISRKLLRLAPDEITRRIDQETH
CCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
LFGERMKSPEAVNAFMRFFQRKKA
HHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]