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The map label for this gene is gap [H]

Identifier: 192289441

GI number: 192289441

Start: 1076213

End: 1077220

Strand: Reverse

Name: gap [H]

Synonym: Rpal_1014

Alternate gene names: 192289441

Gene position: 1077220-1076213 (Counterclockwise)

Preceding gene: 192289442

Following gene: 192289440

Centisome position: 18.75

GC content: 63.69

Gene sequence:

>1008_bases
ATGGCAGTCCGGGTCGCGATCAATGGGTTTGGCCGTATCGGCCGCAACGTTCTGCGGGCGATCTACGAGTCCGGTCGTAA
GGATATCGAAGTCGTTGCGATCAACGATCTCGGCCCGGTCGAGACCAATGCCCATCTGCTCCGCTTCGACTCCGTCCACG
GCCGCTTCCCGTTCGAGGTCAAGGTCGACGGCGACACCATCGATGCCGGCCGCGGCAAGATCAAGGTGACGGCCATCAAG
GATCCGTCGGCGCTGCCGTACAAGGAAGTCGGCGTCGACATCGCGCTGGAATGCACCGGTATCTTCACCGCGCGCGACAA
GGCCGCCACGCTGCTGACCGCTGGCGCCAAGCGCGTGCTGGTTTCGGCTCCGTCGGACGGCGCTGACGCGACCATCGTGT
ATGGCGTCAACCACGAGACCCTGTCCAAGGACCACATGGTGGTTTCGAACGGCTCGTGCACCACGAACTGCCTGGCTCCG
GTCGCCAAGGTGCTCAACGACACCGTCGGCATCGAAACCGGCTTCATGACCACGATCCACGCCTACACCGGCGACCAGCC
GACGCTGGACACCATGCACAAGGATCTCTACCGCGGCCGCGCTGCGGCGATGTCGATGATCCCGACTTCGACCGGTGCCG
CCAAGGCGATCGGCCTGGTGCTGCCGGAGCTGAAGGGCAAGCTGGACGGCGTCGCGATCCGCGTGCCGACCCCGAACGTC
TCGGTGGTCGACCTCAAGATCATCGCCAAGAAGGCCACCACCAAGGAAGAGATCAACGAAGCGATCAAGCGCGCCGCCGA
GCAGGAGCTGAAGGGCATCCTCGGCTACACCAACGCGCCGAACGTCTCGATCGACTTCAACCACGATCCGCACTCGTCCA
CCTTCCACATGGACCAGACCAAGGTGCAGAACGGCACGCTGGTGCGCGTGATGTCGTGGTACGACAACGAGTGGGGCTTC
TCCAACCGCATGGCCGACACCGCCGTCGCGATTGGCAAGCTGATCTAA

Upstream 100 bases:

>100_bases
CGGATTGCAACTGCTCGGCATTTTGGGCATGAAACCGCGCAAGAGTACGGGGCGGGCCCCGCCATAGAACTGAAAATCAT
CTGCAGCGAGGAGAAATTGG

Downstream 100 bases:

>100_bases
TCGACTAAGTCTCGATCTCGTCGACGAAGTCGCTCAGCGACGAAGTCGAAAACGACACGGCGCCTCATGGACCAGGCTCG
GGTGATTACCCGCTTCTCCC

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAVRVAINGFGRIGRNVLRAIYESGRKDIEVVAINDLGPVETNAHLLRFDSVHGRFPFEVKVDGDTIDAGRGKIKVTAIK
DPSALPYKEVGVDIALECTGIFTARDKAATLLTAGAKRVLVSAPSDGADATIVYGVNHETLSKDHMVVSNGSCTTNCLAP
VAKVLNDTVGIETGFMTTIHAYTGDQPTLDTMHKDLYRGRAAAMSMIPTSTGAAKAIGLVLPELKGKLDGVAIRVPTPNV
SVVDLKIIAKKATTKEEINEAIKRAAEQELKGILGYTNAPNVSIDFNHDPHSSTFHMDQTKVQNGTLVRVMSWYDNEWGF
SNRMADTAVAIGKLI

Sequences:

>Translated_335_residues
MAVRVAINGFGRIGRNVLRAIYESGRKDIEVVAINDLGPVETNAHLLRFDSVHGRFPFEVKVDGDTIDAGRGKIKVTAIK
DPSALPYKEVGVDIALECTGIFTARDKAATLLTAGAKRVLVSAPSDGADATIVYGVNHETLSKDHMVVSNGSCTTNCLAP
VAKVLNDTVGIETGFMTTIHAYTGDQPTLDTMHKDLYRGRAAAMSMIPTSTGAAKAIGLVLPELKGKLDGVAIRVPTPNV
SVVDLKIIAKKATTKEEINEAIKRAAEQELKGILGYTNAPNVSIDFNHDPHSSTFHMDQTKVQNGTLVRVMSWYDNEWGF
SNRMADTAVAIGKLI
>Mature_334_residues
AVRVAINGFGRIGRNVLRAIYESGRKDIEVVAINDLGPVETNAHLLRFDSVHGRFPFEVKVDGDTIDAGRGKIKVTAIKD
PSALPYKEVGVDIALECTGIFTARDKAATLLTAGAKRVLVSAPSDGADATIVYGVNHETLSKDHMVVSNGSCTTNCLAPV
AKVLNDTVGIETGFMTTIHAYTGDQPTLDTMHKDLYRGRAAAMSMIPTSTGAAKAIGLVLPELKGKLDGVAIRVPTPNVS
VVDLKIIAKKATTKEEINEAIKRAAEQELKGILGYTNAPNVSIDFNHDPHSSTFHMDQTKVQNGTLVRVMSWYDNEWGFS
NRMADTAVAIGKLI

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=327, Percent_Identity=48.6238532110092, Blast_Score=291, Evalue=6e-79,
Organism=Homo sapiens, GI7657116, Length=326, Percent_Identity=45.398773006135, Blast_Score=266, Evalue=2e-71,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=48.2035928143713, Blast_Score=340, Evalue=9e-95,
Organism=Escherichia coli, GI1788079, Length=335, Percent_Identity=51.3432835820895, Blast_Score=313, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17534677, Length=332, Percent_Identity=50.3012048192771, Blast_Score=297, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI17534679, Length=332, Percent_Identity=50, Blast_Score=297, Evalue=6e-81,
Organism=Caenorhabditis elegans, GI32566163, Length=332, Percent_Identity=48.4939759036145, Blast_Score=279, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17568413, Length=332, Percent_Identity=48.4939759036145, Blast_Score=279, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=49.8507462686567, Blast_Score=300, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6322468, Length=335, Percent_Identity=49.2537313432836, Blast_Score=300, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6322409, Length=328, Percent_Identity=49.0853658536585, Blast_Score=298, Evalue=1e-81,
Organism=Drosophila melanogaster, GI85725000, Length=326, Percent_Identity=49.6932515337423, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI22023983, Length=326, Percent_Identity=49.6932515337423, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI17933600, Length=326, Percent_Identity=49.6932515337423, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI18110149, Length=326, Percent_Identity=49.6932515337423, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=45.0920245398773, Blast_Score=262, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35957; Mature: 35825

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRVAINGFGRIGRNVLRAIYESGRKDIEVVAINDLGPVETNAHLLRFDSVHGRFPFEV
CEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCEEE
KVDGDTIDAGRGKIKVTAIKDPSALPYKEVGVDIALECTGIFTARDKAATLLTAGAKRVL
EECCCEEECCCCEEEEEEECCCCCCCHHHCCEEEEEEEEEEEEECCCHHHEEECCCCEEE
VSAPSDGADATIVYGVNHETLSKDHMVVSNGSCTTNCLAPVAKVLNDTVGIETGFMTTIH
EECCCCCCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
AYTGDQPTLDTMHKDLYRGRAAAMSMIPTSTGAAKAIGLVLPELKGKLDGVAIRVPTPNV
EECCCCCCHHHHHHHHHHCHHHHHEECCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCC
SVVDLKIIAKKATTKEEINEAIKRAAEQELKGILGYTNAPNVSIDFNHDPHSSTFHMDQT
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEECCHH
KVQNGTLVRVMSWYDNEWGFSNRMADTAVAIGKLI
CCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AVRVAINGFGRIGRNVLRAIYESGRKDIEVVAINDLGPVETNAHLLRFDSVHGRFPFEV
EEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCEEE
KVDGDTIDAGRGKIKVTAIKDPSALPYKEVGVDIALECTGIFTARDKAATLLTAGAKRVL
EECCCEEECCCCEEEEEEECCCCCCCHHHCCEEEEEEEEEEEEECCCHHHEEECCCCEEE
VSAPSDGADATIVYGVNHETLSKDHMVVSNGSCTTNCLAPVAKVLNDTVGIETGFMTTIH
EECCCCCCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
AYTGDQPTLDTMHKDLYRGRAAAMSMIPTSTGAAKAIGLVLPELKGKLDGVAIRVPTPNV
EECCCCCCHHHHHHHHHHCHHHHHEECCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCC
SVVDLKIIAKKATTKEEINEAIKRAAEQELKGILGYTNAPNVSIDFNHDPHSSTFHMDQT
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEECCHH
KVQNGTLVRVMSWYDNEWGFSNRMADTAVAIGKLI
CCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]