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The map label for this gene is gst [H]

Identifier: 192289316

GI number: 192289316

Start: 949277

End: 949891

Strand: Reverse

Name: gst [H]

Synonym: Rpal_0888

Alternate gene names: 192289316

Gene position: 949891-949277 (Counterclockwise)

Preceding gene: 192289320

Following gene: 192289311

Centisome position: 16.54

GC content: 63.74

Gene sequence:

>615_bases
ATGAAGCTGTATTATTCACCCGGTGCATGTTCGCTGTCGCCGCATATCGCGCTCAGCGAGGCCGGCCTGCCGTTCGACCT
GGTCAAGGTCGACATCCGGGCGAAGAAGCTGGAGAACGGCGACGACTACGCCGCGATCAATCCGAAGGGGTCGGTGCCTG
CGCTCGGCCTCGACGACGGCTCGGTGCTGACCGAGGGACCGGCGATCGTGCAGTTCATCGCCGACAAGGAAGGCTCCGGC
AAGCTGGCGCCGGCCAACGGATCGCCGGAGCGCTACCGGCTGCAGGAATGGCTGAACTATATCTCGACCGACCTGCACAA
GAGCTTCGGCCCGCTGTTCGCCCCGACGCTCGGCGACGATGCCAAGAATTTCTTCAAGGACCGCATCGCTCGCCACCTCG
GCTATGTCGACAAGCAGCTCGCCGGCAAAGACTATCTGATGGGCTCGTCGTTCACGGTGGCCGACGGCTATCTGTTCGTG
ATCCTGAGCTGGTGCGACCGGATGAAGATCGACCTCGCCCCCTACCCCAACCTCGCCGCCTTCAAGGCCCGCGTCGCCGC
TCGGCCGAAGGTGCAGGAAGCGATGCAAAGCGAAGGGCTGCTGCAGAAGGCGTAA

Upstream 100 bases:

>100_bases
CTGTAGCGCAGTGTATGCAGGTGCATCAATCTTGACTTGCCCATGCAGCGGCATTTAATCGCCCGCGCGCCTGAATCCAA
TCCCGCCGAGGAGGCACTCC

Downstream 100 bases:

>100_bases
GGGATTTCGTTTCTCGCTCGTCATTGCGAGGAGCGAAGCGACGAAGCAATCCAGTGCGGTGCACTGAACTGGATTGCTTC
GCTTCGCTCGCAATGACGGA

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKLYYSPGACSLSPHIALSEAGLPFDLVKVDIRAKKLENGDDYAAINPKGSVPALGLDDGSVLTEGPAIVQFIADKEGSG
KLAPANGSPERYRLQEWLNYISTDLHKSFGPLFAPTLGDDAKNFFKDRIARHLGYVDKQLAGKDYLMGSSFTVADGYLFV
ILSWCDRMKIDLAPYPNLAAFKARVAARPKVQEAMQSEGLLQKA

Sequences:

>Translated_204_residues
MKLYYSPGACSLSPHIALSEAGLPFDLVKVDIRAKKLENGDDYAAINPKGSVPALGLDDGSVLTEGPAIVQFIADKEGSG
KLAPANGSPERYRLQEWLNYISTDLHKSFGPLFAPTLGDDAKNFFKDRIARHLGYVDKQLAGKDYLMGSSFTVADGYLFV
ILSWCDRMKIDLAPYPNLAAFKARVAARPKVQEAMQSEGLLQKA
>Mature_204_residues
MKLYYSPGACSLSPHIALSEAGLPFDLVKVDIRAKKLENGDDYAAINPKGSVPALGLDDGSVLTEGPAIVQFIADKEGSG
KLAPANGSPERYRLQEWLNYISTDLHKSFGPLFAPTLGDDAKNFFKDRIARHLGYVDKQLAGKDYLMGSSFTVADGYLFV
ILSWCDRMKIDLAPYPNLAAFKARVAARPKVQEAMQSEGLLQKA

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787923, Length=200, Percent_Identity=49.5, Blast_Score=190, Evalue=6e-50,
Organism=Escherichia coli, GI1787726, Length=207, Percent_Identity=24.6376811594203, Blast_Score=67, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17864594, Length=188, Percent_Identity=27.1276595744681, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20130115, Length=196, Percent_Identity=29.5918367346939, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 22242; Mature: 22242

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYYSPGACSLSPHIALSEAGLPFDLVKVDIRAKKLENGDDYAAINPKGSVPALGLDDG
CEEEECCCCCCCCCCEEEECCCCCEEEEEEEHHHHCCCCCCCEEEECCCCCCCEECCCCC
SVLTEGPAIVQFIADKEGSGKLAPANGSPERYRLQEWLNYISTDLHKSFGPLFAPTLGDD
CEEECCCCEEEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
AKNFFKDRIARHLGYVDKQLAGKDYLMGSSFTVADGYLFVILSWCDRMKIDLAPYPNLAA
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCHHHHHHHHHHHHCEEECCCCCCHHH
FKARVAARPKVQEAMQSEGLLQKA
HHHHHHCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLYYSPGACSLSPHIALSEAGLPFDLVKVDIRAKKLENGDDYAAINPKGSVPALGLDDG
CEEEECCCCCCCCCCEEEECCCCCEEEEEEEHHHHCCCCCCCEEEECCCCCCCEECCCCC
SVLTEGPAIVQFIADKEGSGKLAPANGSPERYRLQEWLNYISTDLHKSFGPLFAPTLGDD
CEEECCCCEEEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
AKNFFKDRIARHLGYVDKQLAGKDYLMGSSFTVADGYLFVILSWCDRMKIDLAPYPNLAA
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCHHHHHHHHHHHHCEEECCCCCCHHH
FKARVAARPKVQEAMQSEGLLQKA
HHHHHHCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]