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The map label for this gene is lepB [H]

Identifier: 192289320

GI number: 192289320

Start: 952699

End: 953469

Strand: Reverse

Name: lepB [H]

Synonym: Rpal_0892

Alternate gene names: 192289320

Gene position: 953469-952699 (Counterclockwise)

Preceding gene: 192289321

Following gene: 192289316

Centisome position: 16.6

GC content: 69.0

Gene sequence:

>771_bases
ATGACGACGAAGACGGAGACGGCCGCGAGCACCGCGCGGCGCTGGGGCTCGCAGCTGACGCAGCTCGCCGCCGTGGTGGC
GATCGTGCTGGTCGGCAAGGGCGCGGTCGCCGAGCCGTTCTACGTGCCGTCCGGCTCGATGGAGCCGACGCTGCTGATCG
GCGACGCGCTGCTCGCCTCGAAATATCCGTACGGCTATTCGGCAGCGTCGCTGCCGATCCATGTCTCGGTGCCGGAAAGC
GGCCGCGTGTTCGGCTCTACGCCGCACCGCGGCGACGTGGTGGTGTTTCGCTGGTCCGGCGATCGCTCGCAGGTCTGGGT
CAAGCACGTGGTCGGCCTGCCCGGCGACCGGGTGCAGCTCGACAACGGCCGGGTGTTCATCAACGGCGTCGCCGCCAAGG
TAACGCCGGACGGCGTCGGCCGCGCCGAGGATGACAACGGCTCTTATGAGACCGCCGCGCGCTACATTGAGACGCTGCCC
GGCGGCGTCGCCCACCCGATCTTCAAGCTCTACGACAACGGCCGGCTCGACAACACGGCGGAAGTTACGGTGCCGCCCGG
CCACCTGTTCGTGATGGGCGACAATCGCGACAACTCCGCCGACAGCCGCGTGCCGGTGAGCGAAGGCGGCGTCGGCCTGC
TGCCGATCGACGATCTGGTCGGCCGCGTCGATGCCATTGTCGGCTCGTGGAATCCCGTCGTCCGCCGCCAGCCGGTGACG
GATTGGTTCTCAGGCTTCCGCGTCGCGCGGTTCTTCACCGCGGTGCATTGA

Upstream 100 bases:

>100_bases
ACGGCATCGGCACCTGCGGCAAGAACGGCCAGGGGGTCCCGGTGGGTGTCGGCCAGCCGACGCTGCGCATGGACAAGATT
ACGGTCGGAGGCACCGGCGG

Downstream 100 bases:

>100_bases
GCCATAGGGCTTTGAGTCAGAGCGCTTCGCGCGTCAGCGCACCACGCCGGAGATGAACCCGGCCTTGCGGCGCGGCGGCT
TGATCTGGCTCTTCAGGAAA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTTKTETAASTARRWGSQLTQLAAVVAIVLVGKGAVAEPFYVPSGSMEPTLLIGDALLASKYPYGYSAASLPIHVSVPES
GRVFGSTPHRGDVVVFRWSGDRSQVWVKHVVGLPGDRVQLDNGRVFINGVAAKVTPDGVGRAEDDNGSYETAARYIETLP
GGVAHPIFKLYDNGRLDNTAEVTVPPGHLFVMGDNRDNSADSRVPVSEGGVGLLPIDDLVGRVDAIVGSWNPVVRRQPVT
DWFSGFRVARFFTAVH

Sequences:

>Translated_256_residues
MTTKTETAASTARRWGSQLTQLAAVVAIVLVGKGAVAEPFYVPSGSMEPTLLIGDALLASKYPYGYSAASLPIHVSVPES
GRVFGSTPHRGDVVVFRWSGDRSQVWVKHVVGLPGDRVQLDNGRVFINGVAAKVTPDGVGRAEDDNGSYETAARYIETLP
GGVAHPIFKLYDNGRLDNTAEVTVPPGHLFVMGDNRDNSADSRVPVSEGGVGLLPIDDLVGRVDAIVGSWNPVVRRQPVT
DWFSGFRVARFFTAVH
>Mature_255_residues
TTKTETAASTARRWGSQLTQLAAVVAIVLVGKGAVAEPFYVPSGSMEPTLLIGDALLASKYPYGYSAASLPIHVSVPESG
RVFGSTPHRGDVVVFRWSGDRSQVWVKHVVGLPGDRVQLDNGRVFINGVAAKVTPDGVGRAEDDNGSYETAARYIETLPG
GVAHPIFKLYDNGRLDNTAEVTVPPGHLFVMGDNRDNSADSRVPVSEGGVGLLPIDDLVGRVDAIVGSWNPVVRRQPVTD
WFSGFRVARFFTAVH

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=270, Percent_Identity=34.4444444444444, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 27397; Mature: 27266

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00501 SPASE_I_1 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKTETAASTARRWGSQLTQLAAVVAIVLVGKGAVAEPFYVPSGSMEPTLLIGDALLAS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCEEEECCHHHHC
KYPYGYSAASLPIHVSVPESGRVFGSTPHRGDVVVFRWSGDRSQVWVKHVVGLPGDRVQL
CCCCCCCCCCCEEEEECCCCCCEECCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEE
DNGRVFINGVAAKVTPDGVGRAEDDNGSYETAARYIETLPGGVAHPIFKLYDNGRLDNTA
CCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCE
EVTVPPGHLFVMGDNRDNSADSRVPVSEGGVGLLPIDDLVGRVDAIVGSWNPVVRRQPVT
EEEECCCEEEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCHHCCCCCH
DWFSGFRVARFFTAVH
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTKTETAASTARRWGSQLTQLAAVVAIVLVGKGAVAEPFYVPSGSMEPTLLIGDALLAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCEEEECCHHHHC
KYPYGYSAASLPIHVSVPESGRVFGSTPHRGDVVVFRWSGDRSQVWVKHVVGLPGDRVQL
CCCCCCCCCCCEEEEECCCCCCEECCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEE
DNGRVFINGVAAKVTPDGVGRAEDDNGSYETAARYIETLPGGVAHPIFKLYDNGRLDNTA
CCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCE
EVTVPPGHLFVMGDNRDNSADSRVPVSEGGVGLLPIDDLVGRVDAIVGSWNPVVRRQPVT
EEEECCCEEEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCHHCCCCCH
DWFSGFRVARFFTAVH
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA