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The map label for this gene is aroK

Identifier: 192288935

GI number: 192288935

Start: 548412

End: 549014

Strand: Reverse

Name: aroK

Synonym: Rpal_0505

Alternate gene names: 192288935

Gene position: 549014-548412 (Counterclockwise)

Preceding gene: 192288938

Following gene: 192288934

Centisome position: 9.56

GC content: 68.16

Gene sequence:

>603_bases
ATGTCTGAAACCGTACCGACGGCTGCTGCCGGCAGGTCGCCCCAGGAAGCCGAGATCGTCGCGGCGCTGGGCGATCGCCC
GGTCGTGCTCATCGGCATGATGGGCGCCGGCAAATCCACCGTCGGACGCCGGCTGGCGCTGCGACTCGGGCTGCCGTTTC
TCGACGCCGACACCGAGATTGAATCGGCCGCCGCGATGACCATCCCGGAGATCTTCGAAACCCACGGCGAGCCGCATTTT
CGCGACGGCGAGGCCCGGGTGATTTCGCGGCTGCTCGACGGCGGCACCAAGGTGCTGGCGACCGGTGGTGGGGCCTTCAT
GCGCGAGGAAACTCGTGACCGGATTCGCGAGAAGGCGATCTCGATGTGGCTCGAGGCGGAGGCCGACGTGATCCTGCGCC
GGGTCAAGCGCCGCGCGGACCGGCCGCTGCTGAAGACGCCAGATCCGGCCGGCACCATCGCCCGGCTGATCGCCGAACGC
TATCCGCTATACCGCGAAGCCGATATCACCATCGCGTCCCGCGACGTGCCGCACGAGAAGATCGTCGACGAATGCGTCGC
GGCGCTCCACGACTATCTGTGCGCCGCGCCGCCCCAACCTTGA

Upstream 100 bases:

>100_bases
CGCGACTACGACCATGTTCGCCCGTCCCTTGCAAGAGACTCTGGCAAGCCCGGCGACCAGGGTAGTATAGCTTGCCCTTT
CAGTCCCACGGATGCCGAGA

Downstream 100 bases:

>100_bases
GCGAGACTTCATGAACGCCCCGCAGAAACACTCCGCTCCGATCACCGTCGAAGTCGCCCTCGGCGACCGCGCCTATGAGA
TCGTGATCGGCCGCGACGTG

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSETVPTAAAGRSPQEAEIVAALGDRPVVLIGMMGAGKSTVGRRLALRLGLPFLDADTEIESAAAMTIPEIFETHGEPHF
RDGEARVISRLLDGGTKVLATGGGAFMREETRDRIREKAISMWLEAEADVILRRVKRRADRPLLKTPDPAGTIARLIAER
YPLYREADITIASRDVPHEKIVDECVAALHDYLCAAPPQP

Sequences:

>Translated_200_residues
MSETVPTAAAGRSPQEAEIVAALGDRPVVLIGMMGAGKSTVGRRLALRLGLPFLDADTEIESAAAMTIPEIFETHGEPHF
RDGEARVISRLLDGGTKVLATGGGAFMREETRDRIREKAISMWLEAEADVILRRVKRRADRPLLKTPDPAGTIARLIAER
YPLYREADITIASRDVPHEKIVDECVAALHDYLCAAPPQP
>Mature_199_residues
SETVPTAAAGRSPQEAEIVAALGDRPVVLIGMMGAGKSTVGRRLALRLGLPFLDADTEIESAAAMTIPEIFETHGEPHFR
DGEARVISRLLDGGTKVLATGGGAFMREETRDRIREKAISMWLEAEADVILRRVKRRADRPLLKTPDPAGTIARLIAERY
PLYREADITIASRDVPHEKIVDECVAALHDYLCAAPPQP

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=168, Percent_Identity=39.8809523809524, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786587, Length=168, Percent_Identity=32.7380952380952, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_RHOPA (Q6NCG8)

Other databases:

- EMBL:   BX572594
- RefSeq:   NP_945857.1
- ProteinModelPortal:   Q6NCG8
- SMR:   Q6NCG8
- GeneID:   2689302
- GenomeReviews:   BX571963_GR
- KEGG:   rpa:RPA0504
- NMPDR:   fig|258594.1.peg.501
- HOGENOM:   HBG335815
- OMA:   VIYLRAN
- ProtClustDB:   PRK13946
- BioCyc:   RPAL258594:RPA0504-MONOMER
- BRENDA:   2.7.1.71
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 21789; Mature: 21658

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 60-60 BINDING 84-84 BINDING 106-106 BINDING 144-144 BINDING 163-163

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETVPTAAAGRSPQEAEIVAALGDRPVVLIGMMGAGKSTVGRRLALRLGLPFLDADTEI
CCCCCCCHHCCCCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCH
ESAAAMTIPEIFETHGEPHFRDGEARVISRLLDGGTKVLATGGGAFMREETRDRIREKAI
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHH
SMWLEAEADVILRRVKRRADRPLLKTPDPAGTIARLIAERYPLYREADITIASRDVPHEK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCHHH
IVDECVAALHDYLCAAPPQP
HHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SETVPTAAAGRSPQEAEIVAALGDRPVVLIGMMGAGKSTVGRRLALRLGLPFLDADTEI
CCCCCCHHCCCCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCH
ESAAAMTIPEIFETHGEPHFRDGEARVISRLLDGGTKVLATGGGAFMREETRDRIREKAI
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHH
SMWLEAEADVILRRVKRRADRPLLKTPDPAGTIARLIAERYPLYREADITIASRDVPHEK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCHHH
IVDECVAALHDYLCAAPPQP
HHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA