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The map label for this gene is aroB [H]

Identifier: 192288934

GI number: 192288934

Start: 547256

End: 548401

Strand: Reverse

Name: aroB [H]

Synonym: Rpal_0504

Alternate gene names: 192288934

Gene position: 548401-547256 (Counterclockwise)

Preceding gene: 192288935

Following gene: 192288933

Centisome position: 9.55

GC content: 68.15

Gene sequence:

>1146_bases
ATGAACGCCCCGCAGAAACACTCCGCTCCGATCACCGTCGAAGTCGCCCTCGGCGACCGCGCCTATGAGATCGTGATCGG
CCGCGACGTGATCGCCTCGCTGGGCGAGCGGATCGCCAAGCTGCGGCCCGGCGCACGCACCGCGATCGTCACCGATCGCA
CCGTGGCGAAGACCTGGCTGAAGCGCACCGAGGAGGTGCTGGATCAGGTCGGCATCGCGCATGCGTCGGTGATCGTCGGC
GAAGGCGAAAGCTCCAAAAGCTATGCGGGGCTCGAGCAGGTGTGCGAGGCGCTGATCGCCGCCAAGATCGAGCGCAACGA
TCTGGTGATCGCGCTCGGCGGCGGCGTGATCGGCGATCTTGCCGGTTTCTCGGCCTCGCTGCTGCGCCGCGGCGTCGATT
TCGTGCAGGTGCCGACCTCGCTGCTGGCGCAGGTCGACTCCTCGGTCGGCGGCAAGACCGGCATCAACTCGCCGCAGGGC
AAGAATCTGATCGGCACGTTCCATCAGCCGGTGCTGGTCTTGGCCGACACCGCGATCCTCGACACCCTGTCGCCGCGCCA
ATTCCGCGCCGGCTACGCCGAAGTCGCGAAATATGGCGCGCTCGGTGACGAAGCGTTCTTCGCCTGGCTCGAAGCCAACC
ATGCCGAGCTGTTCAGCGGCGGCGCCGCGCGCGAGCACGCGGTGGCCACCTCATGCCGAGCCAAGGCCGCGATCGTCGCC
CGCGACGAACGCGAGACCGGAGACCGCGCGCTGCTCAATCTCGGTCACACCTTCGGCCATGCGCTGGAAGCAGCGACCGG
GTTCTCCGACCGGCTGTTCCACGGCGAGGGCGTGGCGATCGGCATGGTGCTGGCGGCGGAATTCTCGGCCGAGCGCGGCA
TGATGCCGGCAGCCGACGCGCAGCGGCTAGCCAAGCACCTCGCCGACGTCGGCCTGCCGACCCGGCTGCAGGACATCGCC
GGCTTCACCCAGGAAGGCCTTGCCGACGCCGACCGCCTGATGGCGCTGATGTCGCAGGACAAGAAGGTCAAGCGCGGCGA
ACTCACCTTCATCCTGATGGAAGGCATCGGCCGCGCGGTGATCGCCAACAAGGTCGAGCCGGCGCCGGTGCGCGACTTCC
TGCAGCGGAAACTGGCGCAAGCCTAA

Upstream 100 bases:

>100_bases
GCGTCCCGCGACGTGCCGCACGAGAAGATCGTCGACGAATGCGTCGCGGCGCTCCACGACTATCTGTGCGCCGCGCCGCC
CCAACCTTGAGCGAGACTTC

Downstream 100 bases:

>100_bases
AGGCCGCCGCGGCGCCACGCGGTCACGCAGGCGAACCCAAGAGCATCATGAACTCGACTCTGAGCAACGTTCTGATCGCG
GTCCTGCTGCTGATCGCCAA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MNAPQKHSAPITVEVALGDRAYEIVIGRDVIASLGERIAKLRPGARTAIVTDRTVAKTWLKRTEEVLDQVGIAHASVIVG
EGESSKSYAGLEQVCEALIAAKIERNDLVIALGGGVIGDLAGFSASLLRRGVDFVQVPTSLLAQVDSSVGGKTGINSPQG
KNLIGTFHQPVLVLADTAILDTLSPRQFRAGYAEVAKYGALGDEAFFAWLEANHAELFSGGAAREHAVATSCRAKAAIVA
RDERETGDRALLNLGHTFGHALEAATGFSDRLFHGEGVAIGMVLAAEFSAERGMMPAADAQRLAKHLADVGLPTRLQDIA
GFTQEGLADADRLMALMSQDKKVKRGELTFILMEGIGRAVIANKVEPAPVRDFLQRKLAQA

Sequences:

>Translated_381_residues
MNAPQKHSAPITVEVALGDRAYEIVIGRDVIASLGERIAKLRPGARTAIVTDRTVAKTWLKRTEEVLDQVGIAHASVIVG
EGESSKSYAGLEQVCEALIAAKIERNDLVIALGGGVIGDLAGFSASLLRRGVDFVQVPTSLLAQVDSSVGGKTGINSPQG
KNLIGTFHQPVLVLADTAILDTLSPRQFRAGYAEVAKYGALGDEAFFAWLEANHAELFSGGAAREHAVATSCRAKAAIVA
RDERETGDRALLNLGHTFGHALEAATGFSDRLFHGEGVAIGMVLAAEFSAERGMMPAADAQRLAKHLADVGLPTRLQDIA
GFTQEGLADADRLMALMSQDKKVKRGELTFILMEGIGRAVIANKVEPAPVRDFLQRKLAQA
>Mature_381_residues
MNAPQKHSAPITVEVALGDRAYEIVIGRDVIASLGERIAKLRPGARTAIVTDRTVAKTWLKRTEEVLDQVGIAHASVIVG
EGESSKSYAGLEQVCEALIAAKIERNDLVIALGGGVIGDLAGFSASLLRRGVDFVQVPTSLLAQVDSSVGGKTGINSPQG
KNLIGTFHQPVLVLADTAILDTLSPRQFRAGYAEVAKYGALGDEAFFAWLEANHAELFSGGAAREHAVATSCRAKAAIVA
RDERETGDRALLNLGHTFGHALEAATGFSDRLFHGEGVAIGMVLAAEFSAERGMMPAADAQRLAKHLADVGLPTRLQDIA
GFTQEGLADADRLMALMSQDKKVKRGELTFILMEGIGRAVIANKVEPAPVRDFLQRKLAQA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=354, Percent_Identity=45.1977401129944, Blast_Score=258, Evalue=6e-70,
Organism=Saccharomyces cerevisiae, GI6320332, Length=371, Percent_Identity=36.3881401617251, Blast_Score=195, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40393; Mature: 40393

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPQKHSAPITVEVALGDRAYEIVIGRDVIASLGERIAKLRPGARTAIVTDRTVAKTWL
CCCCCCCCCCEEEEEEECCCEEEEEECHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHH
KRTEEVLDQVGIAHASVIVGEGESSKSYAGLEQVCEALIAAKIERNDLVIALGGGVIGDL
HHHHHHHHHHCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHH
AGFSASLLRRGVDFVQVPTSLLAQVDSSVGGKTGINSPQGKNLIGTFHQPVLVLADTAIL
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHH
DTLSPRQFRAGYAEVAKYGALGDEAFFAWLEANHAELFSGGAAREHAVATSCRAKAAIVA
HCCCCHHHHCCHHHHHHHCCCCHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHEEEEE
RDERETGDRALLNLGHTFGHALEAATGFSDRLFHGEGVAIGMVLAAEFSAERGMMPAADA
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEHHHHHHHHHHHCCCCCCHHH
QRLAKHLADVGLPTRLQDIAGFTQEGLADADRLMALMSQDKKVKRGELTFILMEGIGRAV
HHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHH
IANKVEPAPVRDFLQRKLAQA
HHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNAPQKHSAPITVEVALGDRAYEIVIGRDVIASLGERIAKLRPGARTAIVTDRTVAKTWL
CCCCCCCCCCEEEEEEECCCEEEEEECHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHH
KRTEEVLDQVGIAHASVIVGEGESSKSYAGLEQVCEALIAAKIERNDLVIALGGGVIGDL
HHHHHHHHHHCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHH
AGFSASLLRRGVDFVQVPTSLLAQVDSSVGGKTGINSPQGKNLIGTFHQPVLVLADTAIL
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHH
DTLSPRQFRAGYAEVAKYGALGDEAFFAWLEANHAELFSGGAAREHAVATSCRAKAAIVA
HCCCCHHHHCCHHHHHHHCCCCHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHEEEEE
RDERETGDRALLNLGHTFGHALEAATGFSDRLFHGEGVAIGMVLAAEFSAERGMMPAADA
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEHHHHHHHHHHHCCCCCCHHH
QRLAKHLADVGLPTRLQDIAGFTQEGLADADRLMALMSQDKKVKRGELTFILMEGIGRAV
HHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHH
IANKVEPAPVRDFLQRKLAQA
HHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA