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The map label for this gene is cobS [H]

Identifier: 192288929

GI number: 192288929

Start: 542838

End: 543833

Strand: Reverse

Name: cobS [H]

Synonym: Rpal_0499

Alternate gene names: 192288929

Gene position: 543833-542838 (Counterclockwise)

Preceding gene: 192288931

Following gene: 192288928

Centisome position: 9.47

GC content: 62.55

Gene sequence:

>996_bases
ATGACCGCCGCTACGACCACCGCTCCGGAGATCACTGGCTTACCCGACATGAAGGTGTCGGTCCGGCAGGTCTTCGGCAT
CGACAGCGACCTTGAAGTTCCGGCCTATTCCGAGGTCGACCCCCATGTGCCGGATGTTGATCCGGATTACCGTTTCGATC
GCGCCACCACCCTCGCGATTCTGGCAGGCTTCGCCAAGAACCGGCGCGTGATGGTGACCGGCTTCCACGGCACCGGCAAG
TCGACACACATCGAGCAGGTCGCGGCGCGACTCAACTGGCCGTGTGTGCGCGTCAACCTCGACAGCCACATCAGCCGTAT
CGATCTGGTCGGCAAGGACGCCATCGTGGTCCGCGACGGCAAGCAGGTCACCGAATTCCGCGACGGCATCCTGCCCTGGG
CGCTCCAACACAACGTTGCGCTGGTGTTCGACGAATACGATGCCGGCCGCCCGGACGTGATGTTCGTGATCCAGCGCGTG
CTGGAAGTCTCCGGCCGGCTGACGCTGCTCGACCAGAACAAGGTCATCAAGCCGCATCCGGCATTCCGGCTGTTCGCTAC
CGCCAACACCATCGGCCTCGGCGACACGTCGGGCCTGTATCACGGCACGCAGCAGATCAACCAGGGCCAGATGGACCGCT
GGTCGATCGTCACCACACTGAACTATCTGCCGCACGACGAGGAAGTCGAGATCATCCTCGCCAAGGCCAAGCACTATCGC
AATGCCGAAGGGCGCGACATCGTCAACAAGATGGTCCGGCTCGCGGACCTGACGCGCAACGCCTTCGCCAACGGCGATCT
GTCGACCGTGATGAGCCCGCGCACGGTGATCACCTGGTCGGAGAATGCCGAGATCTTCGGCGACATCGGCTTCGCGTTCC
GCGTCACCTTCCTCAACAAATGCGACGAGCTTGAGCGCCCTCTGGTGGCGGAGTTCTATCAGCGCTGCTTCAATGCAGAG
TTGCCGGAGAGCTCGGTCAACATCGCGATGAGCTGA

Upstream 100 bases:

>100_bases
CTTCTGCGGATCGCGGCTCTCTGCTAGGTTCAATTCCGCACTCAACCGCATCCACCAACGAAGATCGGGTTTCGGGCGCG
TCCGGGACCACGGAGGATTG

Downstream 100 bases:

>100_bases
TCCCATGCCTTCAGTTTCCGTCGACCGCACTTATGGCAAGACCAAGAAGGCGGTTCTCGACGGACTGAAGGCCTACAACA
AAGAGCGGTGGGGTCGGCAG

Product: cobalt chelatase, pCobS small subunit

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MTAATTTAPEITGLPDMKVSVRQVFGIDSDLEVPAYSEVDPHVPDVDPDYRFDRATTLAILAGFAKNRRVMVTGFHGTGK
STHIEQVAARLNWPCVRVNLDSHISRIDLVGKDAIVVRDGKQVTEFRDGILPWALQHNVALVFDEYDAGRPDVMFVIQRV
LEVSGRLTLLDQNKVIKPHPAFRLFATANTIGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDEEVEIILAKAKHYR
NAEGRDIVNKMVRLADLTRNAFANGDLSTVMSPRTVITWSENAEIFGDIGFAFRVTFLNKCDELERPLVAEFYQRCFNAE
LPESSVNIAMS

Sequences:

>Translated_331_residues
MTAATTTAPEITGLPDMKVSVRQVFGIDSDLEVPAYSEVDPHVPDVDPDYRFDRATTLAILAGFAKNRRVMVTGFHGTGK
STHIEQVAARLNWPCVRVNLDSHISRIDLVGKDAIVVRDGKQVTEFRDGILPWALQHNVALVFDEYDAGRPDVMFVIQRV
LEVSGRLTLLDQNKVIKPHPAFRLFATANTIGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDEEVEIILAKAKHYR
NAEGRDIVNKMVRLADLTRNAFANGDLSTVMSPRTVITWSENAEIFGDIGFAFRVTFLNKCDELERPLVAEFYQRCFNAE
LPESSVNIAMS
>Mature_330_residues
TAATTTAPEITGLPDMKVSVRQVFGIDSDLEVPAYSEVDPHVPDVDPDYRFDRATTLAILAGFAKNRRVMVTGFHGTGKS
THIEQVAARLNWPCVRVNLDSHISRIDLVGKDAIVVRDGKQVTEFRDGILPWALQHNVALVFDEYDAGRPDVMFVIQRVL
EVSGRLTLLDQNKVIKPHPAFRLFATANTIGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDEEVEIILAKAKHYRN
AEGRDIVNKMVRLADLTRNAFANGDLSTVMSPRTVITWSENAEIFGDIGFAFRVTFLNKCDELERPLVAEFYQRCFNAEL
PESSVNIAMS

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24415404, Length=212, Percent_Identity=25.4716981132075, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323135, Length=192, Percent_Identity=27.0833333333333, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI161076560, Length=210, Percent_Identity=28.0952380952381, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI161076562, Length=210, Percent_Identity=28.0952380952381, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 37003; Mature: 36871

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAATTTAPEITGLPDMKVSVRQVFGIDSDLEVPAYSEVDPHVPDVDPDYRFDRATTLAI
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LAGFAKNRRVMVTGFHGTGKSTHIEQVAARLNWPCVRVNLDSHISRIDLVGKDAIVVRDG
HHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEEECCCEEEEECC
KQVTEFRDGILPWALQHNVALVFDEYDAGRPDVMFVIQRVLEVSGRLTLLDQNKVIKPHP
CHHHHHHCCCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCEECCCC
AFRLFATANTIGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDEEVEIILAKAKHYR
CEEEEEECCEECCCCCCCCCCCHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEEHHHCC
NAEGRDIVNKMVRLADLTRNAFANGDLSTVMSPRTVITWSENAEIFGDIGFAFRVTFLNK
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEECCCCEEEEECCHHEEEHHHHH
CDELERPLVAEFYQRCFNAELPESSVNIAMS
HHHHCCCHHHHHHHHHCCCCCCCCCCEEEEC
>Mature Secondary Structure 
TAATTTAPEITGLPDMKVSVRQVFGIDSDLEVPAYSEVDPHVPDVDPDYRFDRATTLAI
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LAGFAKNRRVMVTGFHGTGKSTHIEQVAARLNWPCVRVNLDSHISRIDLVGKDAIVVRDG
HHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEEECCCEEEEECC
KQVTEFRDGILPWALQHNVALVFDEYDAGRPDVMFVIQRVLEVSGRLTLLDQNKVIKPHP
CHHHHHHCCCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCEECCCC
AFRLFATANTIGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDEEVEIILAKAKHYR
CEEEEEECCEECCCCCCCCCCCHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEEHHHCC
NAEGRDIVNKMVRLADLTRNAFANGDLSTVMSPRTVITWSENAEIFGDIGFAFRVTFLNK
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEECCCCEEEEECCHHEEEHHHHH
CDELERPLVAEFYQRCFNAELPESSVNIAMS
HHHHCCCHHHHHHHHHCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]