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The map label for this gene is bdlA [H]

Identifier: 192288866

GI number: 192288866

Start: 466755

End: 468437

Strand: Reverse

Name: bdlA [H]

Synonym: Rpal_0435

Alternate gene names: 192288866

Gene position: 468437-466755 (Counterclockwise)

Preceding gene: 192288867

Following gene: 192288864

Centisome position: 8.16

GC content: 63.46

Gene sequence:

>1683_bases
ATGTTCTCCTTCACCCGCTCTGCCGGCCATGATCATGCGGCAGCGATGCTCGCGGCGCTCAATCGCTCCCAGGCGGTGAT
CGAGTTTGATCTGGACGGCAACGTCATCGACGCAAACGACAACTTTCTGACCGCGCTCGGCTACTCGCTTCCAGAGATCA
AGGGCAAGCATCACCGGATGTTCGTCGATCCGAGCGAGCACGACAGCACAGCCTATCGCGAGTTCTGGACCGCGTTGCGC
ACCGGCCAGTATCAAGCCGGCGAATTCCACCGCATCGGCAAGGGCGGCCGCGAGGTCTGGATCCAGGCGTCCTACAACCC
GATCCTCGACAAGAACGGCAAACCGACCGGCGTCGTGAAGTTCGCGGCCGACATCACCGCGGCCAAGACCCAATCGCTGG
AGGATGCCGGCAAGCTCGCGGCAATCGGCCGCGCTCAGGCGGTGATCGAGTTTGCGATGGACGGCACCGTCCTCACCGCC
AACGATAACTTTCTCGCCGCGATGGAGTACTCGCTTGGCGAGATCAAGGGCAAGCATCACAGCATGTTTGTCGAGCCGTC
GGTGCGCGAGAGCAGCGACTACCGCGAATTTTGGGCGCGGCTCAACCGCGGCGAATACTTCCCCGGCGAGTTCAAGCGGA
TCGGCAAGGGCGGCAAGGAGGTCTGGATTCTGGCGTCCTACAACCCGATCCTCGACGCACGCGGCAAGCCGTTCAAAGTG
GTGAAATACGCCACCGACGTCACCGCTCAGAAGCTGAAGAACGCCGACTTCTCCGGCCAGATCGATGCGATCCGCAAGTC
ACAGGCGGTGATCGAATTCAGCATCGACGGCACGGTGCTGGACGCCAACGACAACTTCCTGCACGCGCTGGGCTACTCGC
TGGGCGAGATCAAGGGCCGGCATCACAGTATTTTCATCGACCCCGCCGAGCGCGAGAGCGCGGCCTATCGGGCATTCTGG
GCGGCGCTCGGTCGCGGCGATTATCAGGCCGGCGAATACAAGCGCATCGGCAAAGGCGGCAGGGAAGTCTGGATCCAGGC
CTCCTACAACCCGATCCTCGACCTCAATGGGCGGCCTTTCAAGGTGGTGAAATACGCCGCCGACACCACCCGCCAGGTAC
TCACCCGGCTCGGCAACGAGCGCGTCCGCGCCATGATGGAATCGGTCGCGGCCGGAGCGGAGGAGCTGAACGCTTCGGTA
CGCGAGATCTCCGAAGCGATGACCAAGTCGAGGCAGACAGCGATGAACGCCGTCGGCGAAGTCGATGCAGCCGACTCTCA
GGCCAATCAGCTCAACGACGCGGCTCAAGCAATGAGCGGCATCGTCGAACTGATCAACCACATCACCGGGCAGATCAATC
TGCTGGCGCTCAACGCCACGATCGAGTCGGCGCGCGCCGGCGAGGCCGGGCGCGGCTTTGCTGTGGTGGCGGCGGAGGTG
AAGAACCTCGCCAATCAGGCCAAGCAGGCCACCGACAAGATCGGGACCGAGATCAGCAATCTCACCAGCGTCTCCGGCGA
CGTGGTCGGCGCGCTCGGCAAGATCAAGAGCGCGATCCAGAACGTCAGCGAGTACGTCAGCTCGACGGCTGCGGCGGTGG
AGGAGCAGAGCACGGTGACCAGCGAGATGTCGTCGAGCATGCAGCGCGCCGCCGCAGAAGCGGCCGCGATCGCAGCCGGC
TAA

Upstream 100 bases:

>100_bases
GGGGCTAGGCTAAATTTAACGACGTCTTCACCAAAATGGCCGCCAGCTTCTGCTTCCAGGTCGCGCGATCGTGCAAGGCC
GCATCAGGGAAAGGCTTGGA

Downstream 100 bases:

>100_bases
GCGAACCAGCCTCAGGCGACCGCGGACTCGATCGGTGCCGCGCCGCCGATCCCCTGTTTCACGACCTCGCCGAACGCTTC
GAAGTCACCACGGCGGGGCG

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MFSFTRSAGHDHAAAMLAALNRSQAVIEFDLDGNVIDANDNFLTALGYSLPEIKGKHHRMFVDPSEHDSTAYREFWTALR
TGQYQAGEFHRIGKGGREVWIQASYNPILDKNGKPTGVVKFAADITAAKTQSLEDAGKLAAIGRAQAVIEFAMDGTVLTA
NDNFLAAMEYSLGEIKGKHHSMFVEPSVRESSDYREFWARLNRGEYFPGEFKRIGKGGKEVWILASYNPILDARGKPFKV
VKYATDVTAQKLKNADFSGQIDAIRKSQAVIEFSIDGTVLDANDNFLHALGYSLGEIKGRHHSIFIDPAERESAAYRAFW
AALGRGDYQAGEYKRIGKGGREVWIQASYNPILDLNGRPFKVVKYAADTTRQVLTRLGNERVRAMMESVAAGAEELNASV
REISEAMTKSRQTAMNAVGEVDAADSQANQLNDAAQAMSGIVELINHITGQINLLALNATIESARAGEAGRGFAVVAAEV
KNLANQAKQATDKIGTEISNLTSVSGDVVGALGKIKSAIQNVSEYVSSTAAAVEEQSTVTSEMSSSMQRAAAEAAAIAAG

Sequences:

>Translated_560_residues
MFSFTRSAGHDHAAAMLAALNRSQAVIEFDLDGNVIDANDNFLTALGYSLPEIKGKHHRMFVDPSEHDSTAYREFWTALR
TGQYQAGEFHRIGKGGREVWIQASYNPILDKNGKPTGVVKFAADITAAKTQSLEDAGKLAAIGRAQAVIEFAMDGTVLTA
NDNFLAAMEYSLGEIKGKHHSMFVEPSVRESSDYREFWARLNRGEYFPGEFKRIGKGGKEVWILASYNPILDARGKPFKV
VKYATDVTAQKLKNADFSGQIDAIRKSQAVIEFSIDGTVLDANDNFLHALGYSLGEIKGRHHSIFIDPAERESAAYRAFW
AALGRGDYQAGEYKRIGKGGREVWIQASYNPILDLNGRPFKVVKYAADTTRQVLTRLGNERVRAMMESVAAGAEELNASV
REISEAMTKSRQTAMNAVGEVDAADSQANQLNDAAQAMSGIVELINHITGQINLLALNATIESARAGEAGRGFAVVAAEV
KNLANQAKQATDKIGTEISNLTSVSGDVVGALGKIKSAIQNVSEYVSSTAAAVEEQSTVTSEMSSSMQRAAAEAAAIAAG
>Mature_560_residues
MFSFTRSAGHDHAAAMLAALNRSQAVIEFDLDGNVIDANDNFLTALGYSLPEIKGKHHRMFVDPSEHDSTAYREFWTALR
TGQYQAGEFHRIGKGGREVWIQASYNPILDKNGKPTGVVKFAADITAAKTQSLEDAGKLAAIGRAQAVIEFAMDGTVLTA
NDNFLAAMEYSLGEIKGKHHSMFVEPSVRESSDYREFWARLNRGEYFPGEFKRIGKGGKEVWILASYNPILDARGKPFKV
VKYATDVTAQKLKNADFSGQIDAIRKSQAVIEFSIDGTVLDANDNFLHALGYSLGEIKGRHHSIFIDPAERESAAYRAFW
AALGRGDYQAGEYKRIGKGGREVWIQASYNPILDLNGRPFKVVKYAADTTRQVLTRLGNERVRAMMESVAAGAEELNASV
REISEAMTKSRQTAMNAVGEVDAADSQANQLNDAAQAMSGIVELINHITGQINLLALNATIESARAGEAGRGFAVVAAEV
KNLANQAKQATDKIGTEISNLTSVSGDVVGALGKIKSAIQNVSEYVSSTAAAVEEQSTVTSEMSSSMQRAAAEAAAIAAG

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=188, Percent_Identity=32.4468085106383, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI2367378, Length=175, Percent_Identity=34.2857142857143, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787690, Length=188, Percent_Identity=35.1063829787234, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788194, Length=200, Percent_Identity=31.5, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1789453, Length=132, Percent_Identity=35.6060606060606, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 60504; Mature: 60504

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSFTRSAGHDHAAAMLAALNRSQAVIEFDLDGNVIDANDNFLTALGYSLPEIKGKHHRM
CCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEECCCCEEEECCCCCCCCCCCCCEE
FVDPSEHDSTAYREFWTALRTGQYQAGEFHRIGKGGREVWIQASYNPILDKNGKPTGVVK
EECCCCCCHHHHHHHHHHHHCCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEE
FAADITAAKTQSLEDAGKLAAIGRAQAVIEFAMDGTVLTANDNFLAAMEYSLGEIKGKHH
EEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEHHHHHHCCCCC
SMFVEPSVRESSDYREFWARLNRGEYFPGEFKRIGKGGKEVWILASYNPILDARGKPFKV
EEEECCCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEE
VKYATDVTAQKLKNADFSGQIDAIRKSQAVIEFSIDGTVLDANDNFLHALGYSLGEIKGR
EEEHHHHHHHHHCCCCCCCCHHHHHCCCEEEEEEECCEEECCCCCCHHHHCCHHHHCCCC
HHSIFIDPAERESAAYRAFWAALGRGDYQAGEYKRIGKGGREVWIQASYNPILDLNGRPF
CEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEEEECCCCEEECCCCCE
KVVKYAADTTRQVLTRLGNERVRAMMESVAAGAEELNASVREISEAMTKSRQTAMNAVGE
EEEEEHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VDAADSQANQLNDAAQAMSGIVELINHITGQINLLALNATIESARAGEAGRGFAVVAAEV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHCCCCCCCCCEEHHHHH
KNLANQAKQATDKIGTEISNLTSVSGDVVGALGKIKSAIQNVSEYVSSTAAAVEEQSTVT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEMSSSMQRAAAEAAAIAAG
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFSFTRSAGHDHAAAMLAALNRSQAVIEFDLDGNVIDANDNFLTALGYSLPEIKGKHHRM
CCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEECCCCEEEECCCCCCCCCCCCCEE
FVDPSEHDSTAYREFWTALRTGQYQAGEFHRIGKGGREVWIQASYNPILDKNGKPTGVVK
EECCCCCCHHHHHHHHHHHHCCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEE
FAADITAAKTQSLEDAGKLAAIGRAQAVIEFAMDGTVLTANDNFLAAMEYSLGEIKGKHH
EEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEHHHHHHCCCCC
SMFVEPSVRESSDYREFWARLNRGEYFPGEFKRIGKGGKEVWILASYNPILDARGKPFKV
EEEECCCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEE
VKYATDVTAQKLKNADFSGQIDAIRKSQAVIEFSIDGTVLDANDNFLHALGYSLGEIKGR
EEEHHHHHHHHHCCCCCCCCHHHHHCCCEEEEEEECCEEECCCCCCHHHHCCHHHHCCCC
HHSIFIDPAERESAAYRAFWAALGRGDYQAGEYKRIGKGGREVWIQASYNPILDLNGRPF
CEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEEEECCCCEEECCCCCE
KVVKYAADTTRQVLTRLGNERVRAMMESVAAGAEELNASVREISEAMTKSRQTAMNAVGE
EEEEEHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VDAADSQANQLNDAAQAMSGIVELINHITGQINLLALNATIESARAGEAGRGFAVVAAEV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHCCCCCCCCCEEHHHHH
KNLANQAKQATDKIGTEISNLTSVSGDVVGALGKIKSAIQNVSEYVSSTAAAVEEQSTVT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEMSSSMQRAAAEAAAIAAG
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]