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The map label for this gene is yycF [H]

Identifier: 192288717

GI number: 192288717

Start: 305420

End: 306106

Strand: Reverse

Name: yycF [H]

Synonym: Rpal_0286

Alternate gene names: 192288717

Gene position: 306106-305420 (Counterclockwise)

Preceding gene: 192288719

Following gene: 192288716

Centisome position: 5.33

GC content: 65.36

Gene sequence:

>687_bases
ATGCCGAACGCCCGCAAGATCCTGATCGTGGACGACGACAATGATCTGCGCGACGCGCTGGTCGAGCAGCTGTCGCTGCA
CGAGGAATTCGAGGCGTCCGCGGTCGATACCGGCGCCAAGGGCGTGCAGACGGCCAAGGCGCTGTCGCCCGACCTGGTGC
TGATGGACGTCGGCCTTCCCGACACCGACGGCCGCGAAGTGGTGCGAAGCTTGCGCAAGGGCGGCTTCAAGGCGCCGATC
ATCATGCTGACCGGTCACGACACCGACTCGGACACCATTCTGGGCCTGGAAAGCGGCGCCAATGACTACGTGGCCAAGCC
GTTCAGGTTTGCGGTGCTGCTGGCGCGGATCCGCGCCCAGCTGCGCCAGCACGAAGCCAGCGAAGACGCGGTGTTCACGG
TCGGGCCGTATTCGTTCCGTCCCGGCTCGAAGATGCTGACCGGCGCCAACGCCAAGAAGGTGCGGCTGACCGAGAAGGAA
ACCGCGATTCTCCGCTTCCTGTACCGCGCCGGTCAGGCGCCCGTGTCGCGCGAGACCTTGCTGCAGGAGGTGTGGGGCTA
CAATTCTGGCGTCACCACCCACACGCTCGAGACCCACATCTACCGGCTCCGCCAAAAGATCGAGCGCGATGCGGCGAATC
CGGAGATTCTGGTCACCGAGGCCGGTGGCTACAAACTCGTGCCGTGA

Upstream 100 bases:

>100_bases
GGAATCGCTCCCTATCTGGTGATCTGCGATACAATCGCGCGTGATTTGTGTGCGCGCCCCGACGAGAGCCGCGCCGCCAG
ACGACGGAAGGACAGCGCCC

Downstream 100 bases:

>100_bases
TACCAATAAGGGGCCGATTCACTCGTTGCCCGGTCCCGCATGTCGATCGAAGATGATGTTGCCCTGCTCGCGCGCGTTTC
GACGCTGCGGCTGCTCGGCG

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MPNARKILIVDDDNDLRDALVEQLSLHEEFEASAVDTGAKGVQTAKALSPDLVLMDVGLPDTDGREVVRSLRKGGFKAPI
IMLTGHDTDSDTILGLESGANDYVAKPFRFAVLLARIRAQLRQHEASEDAVFTVGPYSFRPGSKMLTGANAKKVRLTEKE
TAILRFLYRAGQAPVSRETLLQEVWGYNSGVTTHTLETHIYRLRQKIERDAANPEILVTEAGGYKLVP

Sequences:

>Translated_228_residues
MPNARKILIVDDDNDLRDALVEQLSLHEEFEASAVDTGAKGVQTAKALSPDLVLMDVGLPDTDGREVVRSLRKGGFKAPI
IMLTGHDTDSDTILGLESGANDYVAKPFRFAVLLARIRAQLRQHEASEDAVFTVGPYSFRPGSKMLTGANAKKVRLTEKE
TAILRFLYRAGQAPVSRETLLQEVWGYNSGVTTHTLETHIYRLRQKIERDAANPEILVTEAGGYKLVP
>Mature_227_residues
PNARKILIVDDDNDLRDALVEQLSLHEEFEASAVDTGAKGVQTAKALSPDLVLMDVGLPDTDGREVVRSLRKGGFKAPII
MLTGHDTDSDTILGLESGANDYVAKPFRFAVLLARIRAQLRQHEASEDAVFTVGPYSFRPGSKMLTGANAKKVRLTEKET
AILRFLYRAGQAPVSRETLLQEVWGYNSGVTTHTLETHIYRLRQKIERDAANPEILVTEAGGYKLVP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=35.8744394618834, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=34.6320346320346, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=32.8888888888889, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.0807174887892, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=34.5132743362832, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=29.646017699115, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789402, Length=205, Percent_Identity=29.2682926829268, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=31.5555555555556, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=28.5067873303167, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=30.9012875536481, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=30.9322033898305, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=31.9327731092437, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787229, Length=236, Percent_Identity=30.5084745762712, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=32.4074074074074, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25116; Mature: 24985

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNARKILIVDDDNDLRDALVEQLSLHEEFEASAVDTGAKGVQTAKALSPDLVLMDVGLP
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEECCCC
DTDGREVVRSLRKGGFKAPIIMLTGHDTDSDTILGLESGANDYVAKPFRFAVLLARIRAQ
CCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHH
LRQHEASEDAVFTVGPYSFRPGSKMLTGANAKKVRLTEKETAILRFLYRAGQAPVSRETL
HHHCCCCCCCEEEECCCCCCCCCCEEECCCCCEEEECHHHHHHHHHHHHCCCCCCHHHHH
LQEVWGYNSGVTTHTLETHIYRLRQKIERDAANPEILVTEAGGYKLVP
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEECC
>Mature Secondary Structure 
PNARKILIVDDDNDLRDALVEQLSLHEEFEASAVDTGAKGVQTAKALSPDLVLMDVGLP
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEECCCC
DTDGREVVRSLRKGGFKAPIIMLTGHDTDSDTILGLESGANDYVAKPFRFAVLLARIRAQ
CCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHH
LRQHEASEDAVFTVGPYSFRPGSKMLTGANAKKVRLTEKETAILRFLYRAGQAPVSRETL
HHHCCCCCCCEEEECCCCCCCCCCEEECCCCCEEEECHHHHHHHHHHHHCCCCCCHHHHH
LQEVWGYNSGVTTHTLETHIYRLRQKIERDAANPEILVTEAGGYKLVP
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]