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The map label for this gene is sdhB [H]

Identifier: 192288646

GI number: 192288646

Start: 233760

End: 234542

Strand: Reverse

Name: sdhB [H]

Synonym: Rpal_0215

Alternate gene names: 192288646

Gene position: 234542-233760 (Counterclockwise)

Preceding gene: 192288647

Following gene: 192288645

Centisome position: 4.08

GC content: 62.84

Gene sequence:

>783_bases
ATGGTTGAATTCGCACTTCCGAAGAATTCGAAGATTGTCGGCGGCAAGACCTGGCCGAAGCCGGAAGGCGCGACCGAGGT
TCGTGAATTCCGCGTCTATCGCTGGAATCCGGACGACGGCAAGAACCCGAGCGTCGACACCTACTACGTCGACAAGCACG
ACTGCGGCCCGATGGTTCTCGACGGCCTGATCTGGATCAAGAACAACATCGACCCGACCCTGACCTTCCGCCGCTCCTGC
CGCGAAGGCGTGTGCGGCTCGTGCGCGATGAACATCGACGGCGAGAACACGCTGGCCTGCACCAAGGCGATGGACGACGT
TCGCGACGACGCCGTGAAGATCAACCCGCTGCCGCACCAGCCGGTGGTGAAGGATCTGGTTCCAGACCTGACCAACTTCT
ACGCGCAATACGCCTCGATCCAGCCCTGGCTGCAGACCGTGACACCGACCCCGCAGAAGGAATGGCGGCAGAGCCACTCC
GACCGCGAGAAGCTCGACGGCCTGTACGAGTGCATCCTGTGCGCCTGCTGCTCGACCTCGTGCCCGAGCTACTGGTGGAA
CTCGGATCGCTTCCTCGGCCCGGCCGCGCTGCTGCAGGCGACCCGCTGGGTCGAAGACAGCCGCGATGAAGCCACCGGCG
AGCGCCTCGACAATCTCGAAGATCCGTTCCGGATCTATCGCTGCCACACCATCATGAACTGCGCCAAGGCGTGCCCGAAG
GGTCTCAACCCGTCGGAAGCGATCGCCAACCTCAAGCTCAAGCTGGTTGAACGCCAGATCTGA

Upstream 100 bases:

>100_bases
TCGTCATGCGCGGACTTGATCCGCGCATCCATCTTCTTCCCAACGAGATGGATCGCCGGGTCGAGCCCGGCAATGACCAG
GAGAGACCAGAGGCAGATCC

Downstream 100 bases:

>100_bases
GCGCGCAAATCGTTGCTGATACCAACGGCCGGGCTTTCGCCCGGCCGTTTTGTTTTGATCACCGATCTCTCCCTGTCATT
GCGAGCGAAGCGAAGCAATC

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MVEFALPKNSKIVGGKTWPKPEGATEVREFRVYRWNPDDGKNPSVDTYYVDKHDCGPMVLDGLIWIKNNIDPTLTFRRSC
REGVCGSCAMNIDGENTLACTKAMDDVRDDAVKINPLPHQPVVKDLVPDLTNFYAQYASIQPWLQTVTPTPQKEWRQSHS
DREKLDGLYECILCACCSTSCPSYWWNSDRFLGPAALLQATRWVEDSRDEATGERLDNLEDPFRIYRCHTIMNCAKACPK
GLNPSEAIANLKLKLVERQI

Sequences:

>Translated_260_residues
MVEFALPKNSKIVGGKTWPKPEGATEVREFRVYRWNPDDGKNPSVDTYYVDKHDCGPMVLDGLIWIKNNIDPTLTFRRSC
REGVCGSCAMNIDGENTLACTKAMDDVRDDAVKINPLPHQPVVKDLVPDLTNFYAQYASIQPWLQTVTPTPQKEWRQSHS
DREKLDGLYECILCACCSTSCPSYWWNSDRFLGPAALLQATRWVEDSRDEATGERLDNLEDPFRIYRCHTIMNCAKACPK
GLNPSEAIANLKLKLVERQI
>Mature_260_residues
MVEFALPKNSKIVGGKTWPKPEGATEVREFRVYRWNPDDGKNPSVDTYYVDKHDCGPMVLDGLIWIKNNIDPTLTFRRSC
REGVCGSCAMNIDGENTLACTKAMDDVRDDAVKINPLPHQPVVKDLVPDLTNFYAQYASIQPWLQTVTPTPQKEWRQSHS
DREKLDGLYECILCACCSTSCPSYWWNSDRFLGPAALLQATRWVEDSRDEATGERLDNLEDPFRIYRCHTIMNCAKACPK
GLNPSEAIANLKLKLVERQI

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=232, Percent_Identity=63.3620689655172, Blast_Score=320, Evalue=9e-88,
Organism=Escherichia coli, GI1786943, Length=234, Percent_Identity=52.1367521367521, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI1790596, Length=227, Percent_Identity=33.0396475770925, Blast_Score=135, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17533915, Length=229, Percent_Identity=61.1353711790393, Blast_Score=306, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6322987, Length=233, Percent_Identity=61.8025751072961, Blast_Score=302, Evalue=4e-83,
Organism=Drosophila melanogaster, GI17137106, Length=253, Percent_Identity=58.8932806324111, Blast_Score=327, Evalue=6e-90,
Organism=Drosophila melanogaster, GI24643156, Length=234, Percent_Identity=61.1111111111111, Blast_Score=301, Evalue=4e-82,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29532; Mature: 29532

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEFALPKNSKIVGGKTWPKPEGATEVREFRVYRWNPDDGKNPSVDTYYVDKHDCGPMVL
CCEECCCCCCEEECCCCCCCCCCHHHHHHEEEEEECCCCCCCCCCCEEECCCCCCCHHHH
DGLIWIKNNIDPTLTFRRSCREGVCGSCAMNIDGENTLACTKAMDDVRDDAVKINPLPHQ
HCEEEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCEEECCCCCC
PVVKDLVPDLTNFYAQYASIQPWLQTVTPTPQKEWRQSHSDREKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
CPSYWWNSDRFLGPAALLQATRWVEDSRDEATGERLDNLEDPFRIYRCHTIMNCAKACPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
GLNPSEAIANLKLKLVERQI
CCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVEFALPKNSKIVGGKTWPKPEGATEVREFRVYRWNPDDGKNPSVDTYYVDKHDCGPMVL
CCEECCCCCCEEECCCCCCCCCCHHHHHHEEEEEECCCCCCCCCCCEEECCCCCCCHHHH
DGLIWIKNNIDPTLTFRRSCREGVCGSCAMNIDGENTLACTKAMDDVRDDAVKINPLPHQ
HCEEEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCEEECCCCCC
PVVKDLVPDLTNFYAQYASIQPWLQTVTPTPQKEWRQSHSDREKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
CPSYWWNSDRFLGPAALLQATRWVEDSRDEATGERLDNLEDPFRIYRCHTIMNCAKACPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
GLNPSEAIANLKLKLVERQI
CCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA